Objective To analyze the status and trend of the development of percutaneous coronary intervention (PCI) in Chinese military hospitals from 2003 to 2004. Methods In April 2005, a registry form was dispatched to all army hospitals, and items in regard of PCI during 2003 to 2004 were asked to be filled for analysis. Results From 2003 to 2004, a total of 16842 cases of PCI performed in 61 PLA hospitals (7052 in 2003, 9790 in 2004) were registered and reported. The intervention procedures were performed in a total of 23706 target lesions, of which only 1632 target lesions (6.9%) were dilated by balloon, and 22074 target lesions (93.1%) were implanted with coronary stents, and 8086 stents among all were drug eluted (36.6% of all stents), including 4270 eluted with rapamycin (Cypher and Firebird, 52.8%), 2072 Paclitaxel eluted (25.6%) and 1744 eluted with other kinds of drug (21.6%). Total success rate of PCI was 97.7% (16449/16842), and success rate was 99.8% in patients with stented procedure. The incidence of major complications and major adverse cardiovascular events was 4.2% (708/16842), including acute occlusion of coronary artery (0.3%), subacute occlusion (0.4%), pericardial tamponade (0.1%), falling of stent (0.1%), emergency coronary artery bypass grafting (0.1%), an inhospital mortality of 1.2% (including death resulted in acute myocardial infarction), and slow-flow or no-flow (1.6%). During follow-up period, target vessel revascularization was done in 5.1% of the patients. Emergency PCI for acute myocardial infarction was performed in 2467 cases, PCI for left main coronary artery and grafted vessel was performed in 576 cases and 137 cases, respectively. Trans-radial PCI was done in 3051 cases. 2124 PCI were done for chronic total occlusion lesions, and the number increased tremendously compared with the last registry. In 57.3% of the hospitals enrolled in the registry, the annual PCI number was less than 100 cases, while in 13.2% of the hospitals the annual number of PCI was over 200 cases, and in only 2 hospitals the annual PCI number was over 1000 cases. Conclusions The annual case numbers of PCI in PLA hospitals within the recent two years increased by around 40% every year. The success rates for complicated lesions, the use of new technique, and the complication rate of PCI were comparable with that reported in domestic and foreign literature published in recent years. It is noted that, the development has been quite different among different hospitals, so that technical training and cooperation should be emphasized in the future.