The Pierre Robin sequence (PRS)is a congenital abnormality which is not only causally heterogeneous but also with a group of physical findings, characterized by the presence of the combination of underdeveloped(micrognathia) or retropositioned(retrognathia) mandible,glossoptosis that leads to respiratory tract obstruction with or without cleft palate. PRS is clinically defined by obstruction of the upper airways, feeding difficulties, inspiration pneumonia and some accompany with multiple -anomalies that are more frequent and more severe during the immediate postnatal and neonatal period. Diagnosis of PRS may be made immediately when a neonate presents in respiratory distress with micrognathia. Further examination may show the posterior placement of the tongue and possibly a cleft palate. Now that the strong association of PRS with many multiple - anomaly syndromes is recognized, treatment must be individualized to optimize the outcome. Most PRS children have failure to thrive,and long -term outcomes vary greatly,depending on whether the PRS is an isolated occurrence or part of an associated syndrome and on whether the infant experienced any obstructive-hypoxic episodes.

The birth rate of very low birth weight(VLBW)is rising year by year,and its survival rate increases with developing of modern methods of neonatal intensive care.The outcomes of VLBW have become a social concern.VLBW have different brain structure compared with term children,mainly in the reduction of brain volume.including the reduction of gray matter volume and white matter vollame.Because of these pathologic changes in brain.some VLBW show severe neurodevelopmental disorders in childhood,including cognitive problems.behavioral and psychological problems,motor clumsiness and so on.

Purpose CT spectroscopy imaging was used in the preoperative differentiation evaluation of renal clear cell carcinoma, to access its malignant degree preoperatively, and to guide the operation treatment. Materials and Methods The spectral characteristics of 40 patients with renal clear cell carcinoma (RCCC) were analyzed retrospectively, all the RCCC patients underwent gemstone spectral imaging (GSI) scans, to obtain spectral serial images for the arterial phase and medulla phase. Spectral characteristic parameters and spectrum curve between different grades of renal cell carcinoma was compared, and the results were compared with pathology. Results Among the 40 cases of patients, carcinoma of grade I, II and III were 13 cases, 15 cases and 12 cases respectively. CT value ratio of renal clear cell carcinoma of grade I, II and III under 70 keV were 1.17±0.25, 0.84±0.85 and 0.64±0.19 (F=23.697, P<0.05) in arterial phase and 0.83±0.12, 0.64±0.07 and 0.54±0.08 (F=30.975, P<0.05) in medulla phase;iodine concentration ratio was 1.19±0.40, 0.60±0.10 and 0.25±0.94 (F=32.932, P<0.05) in arterial phase, and 0.69±0.18, 0.43±0.94 and 0.26±0.51 (F=28.673, P<0.05) in medulla phase. Spectrum curve slope of renal clear cell carcinoma of grade I, II, III in arterial phase was 4.00±1.24, 2.16±0.95 and 0.92±0.64 (F=23.392, P<0.05), and 3.54±1.20, 2.70±0.71 and 1.20±0.44 (F=24.272, P<0.05) in medulla phase. Differences of water concentration in arterial and medulla phase between renal clear cell carcinoma with different grade were not statistically signiifcant (P>0.05). Conclusion The differences of CT value, energy spectrum curve slope, iodine value under CT spectroscopy single energy imaging between renal clear cell carcinoma with different nuclear grade were statistically signiifcant, which can be expected to provide the basis for preoperative therapy selection.

Inflammasomes are multiprotein complexes that can recognize pathogenic microorganisms and stress -asso-ciated endogenous molecules and play an important role in innate immune system .Inflammasomes cause inflamma-tion response by inducing maturation of inflammatory cytokines interleukin ( IL)-1βand IL-18 through activation of caspase-1 ,and involve in the pathogenesis of various diseases such as cryopyrin-associated periodic syndrome , is-chemia-reperfusion injury and atherosclerosis .

The effects of high frequency jet ventilation(HFJV) on brain resuscitation had been investigated in 28 cats in which simple brain functional failure was produced by occlusion of both carotid and both vertebral arteries. The results suggested that HFJV could improve endurance of cats when subjected to brain ischemia, raise the survival rate of cats with reversible brain functional failure, and prolong the survival time of cats with permernent brain functional failure. The mechanisms of how HFJ would exert beneficial effect on brain resuscitation was discussed.

Objective To evaluate the values of computer tomography in differential diagnosis of parotitis and tumors.Methods CT findings of the 18 parotitis cases and 25 parotid tumors cases proved by pathology was analysed retrospectivety statistically.Results Most of parotitis appeared in both side(10/18),all of the parotid tumors were in unilateral parotid(25/25)(?0.05)).The border of the unilateral and local parititis was clear(2/5),mixed tumors were well-defined(5/6)(?

Malnutrition has traditionally been regarded as a global concern,especially in the developing countries. Malnutrition seems more prevalent in hospitalized patients, with potentially serious consequences, it may increase susceptibility to infection and mortality and lengthen the stays in hospital,which lead to additional health care costs. Along with the development of the screening tools,it plays an increasingly important role in the nutritional problems in adults. Recently several nutritional screening tools have been applied in pediatrics,but the lack of the universal acceptable tools is still a problem demanding prompt solution. This review aims to compare the nutritional screening tools that are currently available in clinic and their drawbacks in daily work.

OBJECTIVE To investigate the distribution and drug resistance of Pseudomonas aeruginosa.METHODS All specimens isolated and cultured from patients in our hospital were identified by using the automatic microorganism analyzer WalkAway-40,Dade Behring made in America,and bacteria′s drug susceptibility test and identifications were performed on strains using NC21 Microscan Panel.RESULTS From sixty-two strains of P.aeruginosa 36 strains were isolated of sputum.The resistance rate to the third generation of cephalosporins cefotaxime and ceftriaxone was 55.6% and 47.5%,respectively.The resistance rate to the other ?-lactamases antibiotics such as ceftazidime was 7.5%,piperacillin/tazobactam 11.0%,cefepime 14.8% and penicillin was 30.0%,the ratio of resistance for imipenem was 20.0%,the lowest one was amikacin(4.6%).CONCLUSIONS P.aeruginosa is one of the main bacteria in the lower respiratory tract infection.The drug-resistant mechanism of P.aeruginosa is very complex,including multidrug resistance characteristics,and it is originally resistant to several antibiotics.To avoid being produced ?-lactamases and result in resisting drug widely,the antibiotics should be selected according to low drug-resistant rate and taking into account sufficiently its drug resistance mechanism in the treatment of P.aeruginosa infection.

Objective To observe the therapeutic effect of Sanzi Yangqing Decoction (Decoction of three kinds of seeds) for mammary cystic hyperplasia.Methods Totally 113 patients with mammary cystic hyperplastia were randomized into a treatment group (58 cases) which was prescribed Sanzi Yangqing Decoction and a control group (55 cases) which was given Ruhe Sanjie Tablet (Tablet for dissolving mammary masses). Both were treated for 3 courses. Before and after treatment the clinical symptoms and signs, hormones in serum of both groups, and the indices of hemodynamics of the treatment group were observed.Results The total effective rate of the treatment group was 89.66%, while that of the control group was 65.45%, there was significant difference (P

Posterior ischemic optic neuropathy is a kind of ischemic optic neuropathy, the incidence rate of which is lower with less obviously clinical features, less positive signs and more difficultly diagnosis when compared with anterior ischemic optic neuropathy.Meanwhile, therapeutic method of posterior ischemic optic neuropathy has remained controversial.This article will summarize the research development of the auxiliary examination, diagnosis, differential diagnosis and therapeutic method of posterior ischemic optic neuropathy.