1.Diagnostic and treatment of functional constipation in infant
Journal of Chinese Physician 2017;19(3):349-351
Infant functional constipation is one of the common clinical symptoms in infancy stage,so far we do not have a specific diagnostic criteria and treatment for infant functional constipation.In this paper,we reviewed the diagnostic methods,clinical evaluation,differential diagnosis,and treatment recommendations according to recent research results for infant functional constipation.
2.Application of low power laser irradiation and olfactory ensheathing cell transplantation in treatment of spinal cord injury
Chinese Journal of Tissue Engineering Research 2007;0(51):-
Spinal cord injury has been considered the disease seriously suffering people.Their oligodendrocyte cells cannot form the channel guide to axons' migrating and secrete inhibitors,as well as astrocytes format glial scar in the injured district after rapidly reactive proliferation and inhibit axon growth.Thus,the treatment of spinal cord injury is still a thorny issue in medical field at present.Olfactory ensheathing cells have a good specific process axis linking of axon regeneration and accurately target.The effects of low power laser irradiation on the nervous system and olfactory ensheathing cells not only included its reservations and even promotion of the activity of damaged neurons,decrease in scar formation,prevention of the degeneration of neurons,but also increase in olfactory ensheathing cell activity by intervening some factors.Olfactory ensheathing cell transplantation and low power laser irradiation play an important role in the repair of spinal cord injury.
3.Comparison of Validity of the Methods for Estimating Target Height
Weibin ZHU ; Peizheng CHEN ; Longmei QIU
Journal of Chinese Physician 2002;0(S1):-
18 years(n=160) were included. CMH method and FPH model were applied to analyse statistically final height of Shanghai children and their midparental height. Results There was a considerable disparity in stature between the Chinese and the Swedish study populations(P
4.Observation of Clinical Efficacy of Dong’s Pushing Epiglottis Cartilage Method for the Treatment of Children Food Retention
Shuxia WANG ; Haiqiong HAN ; Weibin CHEN
Chinese Journal of Information on Traditional Chinese Medicine 2015;(10):21-24
Objective To observe the clinical efficacy of Dong’s Pushing Epiglottis Cartilage Method for the treatment of children food retention through randomized, parallel and controlled clinical trial.Methods Totally 72 children diagnosed with children food retention were randomly divided into treatment group and control group, 36 cases for each group. Children of the treatment group were treated with Dong’s Pushing Epiglottis Cartilage Method, while children of the control group were treated with acupuncture Four Seam. The clinical symptoms, gastric half-emptying time and antral contraction frequency of the two groups before and after the treatment were compared. Results After treatment, integral of clinical symptom in both groups were obviously improved compared with before treatment (P<0.05), but there was no significant difference between the two groups (P>0.05). After treatment, gastric half-emptying time and antral contraction frequency of the both groups were obviously improved, with significant difference (P<0.05), but there was no significant difference between the two groups (P>0.05). The total effectiveness of the treatment group was 97.2% (35/36) and the control group was 94.4% (34/36), with no significantly difference (P>0.05).Conclusion Dong’s Pushing Epiglottis Cartilage Method has relatively good clinical efficacy for the treatment of children food retention.
5.Research and development of a computer-based patient record system
Weibin WU ; Qiang XIAO ; Lianzhong CHEN
Chinese Journal of Hospital Administration 1996;0(04):-
Objective To research and develop a computer-based patient record (CPR) system so as to realize the collection, processing, storage, transmission and application of patient information. Methods A CPR system was accomplished through developing a structural patient record, a text editor, techniques of database security, a knowledge base of on-line help, real-time monitoring, print control and function expansion. Results The CPR system, established with the above techniques, was put into use in two third-tier hospitals. It was proved via practice that the system, sound in operation, safe and stable, easy to maintain, and compatible, enhanced medical quality and clinical efficiency. Conclusion ①Creating a structural patient record is the basis of realizing CPR. ②Developing a specialized editor is the key to bringing about CPR. ③Possessing perfect database security techniques is the guarantee for starting CPR. ④Constructing a knowledge base of on-line help is an effective way to help doctors raise the level of their clinical decisions. ⑤The CPR system is an effective means of improving the quality of patient records.⑥The CPR system is also an effective means of improving the efficiency of patient record writing.
6.Therapeutic Effect of Urinary Retention due to Hyperplasis of Prostate Gland by Combining Electric Acupuncture to Ciliao and Zhongliao Acupoints with Ultrashort Wave Therapy
Xianghua YU ; Weibin GAO ; Lina CHEN
Journal of Zhejiang Chinese Medical University 2006;0(04):-
[Objective ] To evaluate the curative effect of urinary retention caused by hyperplasia of prostate gland after treatment of electric acupuncture to Ciliao and Zhongliao acupoints combined with ultrashort wave therapy.[Methods] 35 patients were treated by electric acupuncture to Ciliao and Zhongliao acupoints cooperating with ultrashort wave therapy.Residual urine volumn(RUV),frequency of urinary retention,the therapeutic effect and follow-up were recorded and statistically analyzed.[Results] 29 patients were able to urinate after the therapy,except for 6 patients who were still in urinary retention condition.Effective rate were up to 82.8%.[Conclusion] It proved that the less the frequency was,the better the clinical effect would be.However,no matter how frequent the retention was,our combination therapy still worked,and both effects of the near future and long-term were proved to be fine.Special therapeutic action from Shu acupoint,electric acupuncture's electric current effect,and physical therapy of ultrashort wave contributed to the outcome.
7.Effects of Ganoderma lucidum and it combined with Radix Salvia e Miltiorrhizae, Radix Bupleuri, and Fructus Schisandrae Chinensis respectivel y on experimental hepatic injuries in mouse
Xiaoli CHEN ; Shengchun WANG ; Weibin TIAN ; Yongwu HU
Journal of Third Military Medical University 2001;23(5):567-570
Objective To investigate the protective effects of alcoholic extracts of Ganoderma lucidum (GL) and its combination with Rad ix Salviae Miltiorrhizae (RSM), Radix Bupleuri (RB), and Fructus Schisandrae Chi nensis (FSC) respectively on experimental hepatic injuries. Methods Hepatic injury models were established with the injections of carbon tetrac hloride (CCl4) or D-galactosamine(D-GlaN) into mouse, and then the therapeut ic agents at same dose were given respectively. The activity of cholinesterase(C hE) and alaline aminotransferase(ALT) in the serum and hepatic homogenate, the c ontents of malonyl dialdehyde (MDA), alkaline phosphatase (ALP) and reduced glut athione (GSH) in hepatic homogenate from all mouse were determined. The morpholo gic changes of the livers were also observed with VG staining. Results In CCl4 treated mice, serum ALT activity was increased markedly wh ile ChE acti vity decreased significantly. GL and GL+RB, GL +FSC could relieve these changes ; GL combined with all other agents could inhibit the GSH accumulation, but only GL+FSC had a suppressive effect on MDA increase and made it return to normal. For D-GlaN treated mice, all agent groups had little effect on the activity of ChE; Only GL dramatically reduced the increased activity of ALT; GL +RSM could e liminate the GSH, but not significant; GL and all GL combinations could decrease the increased MDA (P<0.01). Pathological observation showed that hepatocyte damage in GL group and GL+FSC group incline d to recover. Conclusion The results indicate that Ganoderma lucidum is an effective agent against hepatic injuries, especially combined wi th F ructus Schisandrae Chinensis, which may be associated with its anti-hepatocyte oxidation.
8.Effects of leptin on hypoxia-induced apoptosis in cultured alveolar typeⅡ cells of fetal rat and its mechanism
Hui CHEN ; Dongzi YANG ; Weibin CAI ; Zhenhua WANG ; Jianping ZHANG
Chinese Journal of Pathophysiology 1989;0(05):-
AIM: To investigate the effects of leptin (LEP) on the alveolar type Ⅱ cells(AECⅡ) apoptosis induced by Na2S2O4 and explore the molecular mechanisms. METHODS: Primary AECⅡ culture was prepared according to a specific immunosorption procedure with slight modification and the cells were identified by transmission electron microscope and immunocytochemistry. AECⅡ damage was induced by 5 mmol/L Na2S2O4. LEP group cells were treated with LEP at concentrations from 100 ?g/L to 1 600 ?g/L. The cell survival rate was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays. Cell cycle and apoptosis were analyzed by flow cytometry and the level of caspase-3 was measured by Western blotting. RESULTS: Highly purified AECⅡ, obtained by the method of modified immunosorption, were identified with the positive expression of SP-A and intracellular lamellarbodies were found under electron micrography. The cells, exposed to 5 mmol/L Na2S2O4, showed characteristic changes of apoptosis and activation of caspase 3. These damages were relieved by the treatment of LEP (100-1 600 ?g/L), with survival increasing, apoptosis peak decreasing, cell morphology restoring and caspase 3 activation inhibiting.CONCLUSION: Leptin prevents AECⅡ from apoptosis induced by Na2S2O4 or hypoxia. The potential mechanism of its action may be related to promoting cell cycle from G1 phase to S phase and inhibiting the activating of caspase 3.
9.To evaluate the application value of 2 5 6-slice spiral CT angiography in lower extremity arteriosclerosis obliterans patients after grafts operation
Weibin CHEN ; Li FENG ; Fengling GONG ; Huiying ZHANG ; Zhilan LIU
Journal of Practical Radiology 2014;(4):600-602,634
Objective To evaluate the application value of 256 slice spiral CT angiography (CTA)in the bridge vessels lesions af-ter grafts operation in lower extremity arteriosclerosis obliterans patients.Methods Taken DSA as the gold standard,using 256 slices spiral CTA to analysis the post-processing image of 76 article Bridge vascular which can be assessed in 65 cases patients with lower extremity arteriosclerosis obliterans,and to evaluated the diagnosis accuracy,sensitivity,specificity,positive predictive rate and negative predictive rate of postoperative bridge intravascular lesions.Results Using 256 slices spiral CTA,the bridge vascular of grafts operation patients can be clearly displayed,stenosis or unobstructed,and the anastomosis of the bridge vascular.5 graft occlu-sion,22bridge intravascular plaque were diagnosed correctly,3 vascular lesions were undiscovered.The accuracy,sensitivity,speci-ficity,positive predictive rate and negative predictive rate were 98.15%,96.15%,97.90%,92.59% and 97.96% respectively. Conclusion Using 256 slices spiral CTA can clearly show the endovascular lesions of lower extremity arteriosclerosis obliterans after grafts operation,and has high accuracy and specificity.It can be safely used as one of noninvasive follow-up means after grafts oper-ation.
10.The anatomical relationship of the internal thoracic artery and coronary artery evaluated by 256 slice spiral CT
Weibin CHEN ; Li FENG ; Fengling GONG ; Huiying ZHANG
Tianjin Medical Journal 2015;(9):1056-1058,1059
Objective To evaluation the anatomy relationship between thoracic artery and coronary artery by using 256 layer spiral CT angiography. Methods The angiographic images of thoracic aortic and coronary artery angiography were re?vealed in 200 patients with chest pain. Values of the major branch length, diameter, length of the aorta-coronary artery by?pass on both sides of the thoracic artery and coronary artery were measured. Results The diameter of thoracic artery was (2.52±0.38) mm, and the length of thoracic artery from the starting point to terminal was (190.12 ±1.90) mm. There were no significant differences in the thoracic artery lumen diameter and length between both sides. The inner diameters of left anteri?or descending coronary artery, left circumflex, diagonal branch, right coronary artery and the posterior interventricular branch were (2.82 ±0.25), (2.60±0.12), (2.22±0.25), (3.02±0.27) and (2.35±0.35) mm respectively. There were no significant differences in thoracic artery diameters except for the right coronary artery diameter, which was higher than that of the thorac?ic artery. About free transplantation the length from 2cm above in the ascending aorta starting to the halfway point of anterior descending coronary artery, to the atrioventricular node along the left circumflex way, to the atrioventricular node along the right coronary artery and from the atrioventricular node to halfway point of posterior interventricular branch was shorter than that of thoracic artery (P<0.05). About situ transplantation in addition to the length from the thoracic artery start department to the point of anterior descending compared with the thoracic artery length, there were no statistical significance ( P>0.05). The length from the thoracic artery start department to the left-hand atrioventricular node, to the right coronary artery atrio?ventricular node was higher than that of the thoracic artery length (P<0.05). Conclusion The branches of internal thoracic artery and coronary artery are similar. About situ transplantation is suitable for the wall blood vessels before the heart. With free thoracic artery transplantation, its length can meet any bridging from the ascending aorta to the coronary arteries.