1.Prevention and treatment of post-prostatectomy incontinence
China Oncology 2014;(3):231-234
Postoperative incontinence is one of the most feared complications of radical prostatectomy with a major impact on patients’ quality of life. There are several ways to treat with the incontinence including pelvic lfoor muscle training and medication as the conservative treatment, nerve-sparing approach during the operation and the urethral sling and the artificial urinary sphincter placement as the operative treatment. The aim of this article is to evaluate the treatment stated above to provide some guidance to deal with post-prostatectomy incontinence.
2.Histologic and Clinical Characteristics of Skin Warts According to the Human Papillomavirus Antigen Expression.
Kun Chang SONG ; Kwang Gil LEE
Korean Journal of Pathology 1993;27(4):379-386
Skin wart is an infectious disease of human papillomavirus(HPV). Its clinical and histopathologic characteristics are largely determined by lesion sties, viral type and host immunity. The infected basal cells and keratinocytes of the epidermis are induced to proliferate by the viral genome. It is, however, not well known how htose factors give rise to histopathologic alterations in the infected basal cells and keratinocytes. So, evaluation of correlation between HPV antigen expression in the wart tissues and clinical and histopathologic charateristics was done on 83 cases of skin warts. The age of patients ranged from 2 to 83 years. Thirty six(43.3%) cases were diagnosed before the age of third decade. The sex ratio was nearly same. Verruca vulgaris was most common(46 cases), followed by verruca plana(26 cases) and verruca palmoplantaris(11 cases). HPV antigen expression was observed in 43 out of total 83(51.8%). It was noted in 47.8%(22/46) of verruca vulgaris, in 46.2%(12/26) of verruca plana and in 81.8%(9/11) of verruca palmoplantaris. HPV antigen-positive groups included more younger patient's age and more higher PCNA than those of HPV negative groups. HPV positive groups also tend to have shorter duration of disease and more numerous mitoses than HPV negative groups. HPV antigen-positive groups showed lower inflammation grade than that of HPV negative groups(p<0.05). The higher the inflammaton grade is, the lower the HPV antigen expression rate. In summary, HPV antigen expression in cutaneous wart tissue is significantly correlated with the proliferative activity of the lesion. It is also significantly correlated with the inflammation that is considered to be the result of cell-mediated immune reaction.
Humans
3.Idiopathic Intestinal Lymphangiectasia.
Korean Journal of Pathology 1994;28(3):319-321
This is a case report of idiopathic intestinal lymphangiectasia occurring in a 3-year-old boy. Idiopathic intestinal lymphangiectasia is believed to be a part of the generalized congenital disorder of lymphatic system. The present case revealed markedly ectatic lymphatics in the lamina propria of duodenal villi with lymphorrhagia. Clinical features were typical of the protein-losing enteropathy; hypoalbuminemia, hypocalcemia, chylous ascites, edema of the lower extremities and mild lymphocytopenia. This case indicates that serious protein loss may ensue, even in cases of intestinal lymphangiectasia without abnormalities of extraintestinal lymphatics.
4.Fine needle aspiration cytology of giant cell tumor of the rib-report of a case-.
Kun Chang SONG ; Kwang Gill LEE
Korean Journal of Cytopathology 1993;4(1):70-73
No abstract available.
Biopsy, Fine-Needle*
;
Giant Cell Tumors*
;
Giant Cells*
5.Identification of the expression of recombinated plasmid pLNCX-EGFP-C1-hri in PA317 packaging cell line
Ning DING ; Kun LI ; Ming CHANG
China Medical Equipment 2014;(9):9-11
Objective:To identify the expression of plasmid pLNCX-EGFP-C1-hri targeting the gene of Human ribonuclease inhibitor (hri) in PA317 cells which is capable of expression in mammalian cells.Methods: The vector of pLNCX-EGFP-C1-hri was transfected into PA317 cells by Lipofectamine 2000 and then the expression of recombinated plasmid was verified in living cells by observing the transcription level of egfp-hri fusion gene mRNA with RT-PCR method and the expression level of egfp-fusion hRI protein with western blotting method respectively.Results: Both RT-PCR and western blotting showed the egfp-hri fusion gene was obviously expression in PA317 cells.Conclusion: The plasmid of pLNCX-EGFP-C1-hri targeting hRI is successfully constructed and the protein of hRI can be expressed in PA317 cells correctly.
6.An Experimental Study of the Effect of Bone Cement upon the Epiphyseal Plate of Growing Rabbits
The Journal of the Korean Orthopaedic Association 1979;14(2):309-313
Acrylic bone cement is now widely used in surgery for many purposes. Therefore, the effect of bone cement on the growth plate of a growing bone may be an interesting subject, particularly in the orthopedic field. The authors carried out an experiment to study the effect of bone cement on the growth plate of the bone, using 32 growing rabbits weighing from 800 to 1000 gm, which were divided into 2 main groups. In Group I, which was the control group, the growth plates were injured mechanically by inserting a Kirschner wire and a stainless screw, 1.5 mm and 2.5 mm in diameter, respectively, which were then removed. In Group II, the growth plates were also injured by the same method as in Group I, and bone cement was inserted into the holes made by the insertion of the Kirschner wire and the screw. Then the histological findings of the injured plates were studied at 2, 4, 6 and 10 weeks after injury. Following observations were made. 1. In Group I, in which the growth plates were only mechanically damaged, the histologic changes were localized only in that portion of the plate which had been injured by a wire or a screw, leaving the rest of the plate relatively normal. In Group II, the extent and severity of the injury were more wide and severe. 2. Proliferation of mesenchymal fibroblasts and deformity of the growth plate were more severe in Group II. 3. In both groups the extent and severity of growth plate injury were more marked when injured by a screw.
Congenital Abnormalities
;
Fibroblasts
;
Growth Plate
;
Methods
;
Orthopedics
;
Polymethyl Methacrylate
;
Rabbits
7.Ligamentum flavum hematoma in the lumbar spine mimicking epidural tumor: A case report
Cheng-Ta Hsieh ; Chih-Ju Chang ; Kun-Chuan Chang
Neurology Asia 2015;20(3):309-311
Nerve root compression due to ligamentum flavum hematoma is extremely rare, with less than 70
cases reported in the literature. The clinical presentation and images were similar to those of spinal
epidural tumors. Herein, we reported a previously healthy 64-year-old female who presented with
right radicular leg pain. Neurological examination was consistent with right L5 root compression.
The magnetic resonance imaging revealed a mass posterior to the L5 thecal sac, appearing as high
intensity on T1-weighted and T2-weighted images. During operation, the dark hematoma within the
ligamentum flavum was found. The pathological examination confirmed the diagnosis of hemorrhage.
Her prognosis following surgery was excellent.
Sciatica
8.Problems in Humeral Interlocking with Seidel Nail
Koing Woo KWUN ; Sin Kun KIM ; Sang Wook LEE ; Chang Hyuk CHOI ; Jin Kun LEE
The Journal of the Korean Orthopaedic Association 1996;31(2):199-204
Seidel nail is one of locked humeral nail and Seidel himself reported excellent result in his preliminary report using his nail. But our early experience showed disappointing result with high rate of complications, So we reviewed our 16 cases of humeral shaft fracture with polytrauma treated with Seidel nail and studied anatomical fitness of the nail within the distal medullary space using CT scan. The most frequent complication was intraoperative fracture of the proximal humerus < 4 cases> and this seemed to be due to lateral placement of pilot hole. There were 3 cases of nonunion and these cases showed insufficient distal anchorage, either primarily or postoperatively. Anatomical fitness study showed insufficient spreading of nail flanges in 5 cases of distal canal width below 9mm and nonunion cases were in this group. Other problems of Seidel nail were technical difficulties due to occasionally incorrect proximal targeting device and frequent breakage of adaptor screw. Study of more cases may be needed to confirm the design problem of Seidel nail.
Humerus
;
Multiple Trauma
;
Tomography, X-Ray Computed
9.Therapeutic Effect of Iron Deficiency Anemia.
Dong Suk LEE ; Chang Hee HAN ; Kun Soo LEE
Journal of the Korean Pediatric Society 1990;33(6):799-806
No abstract available.
Anemia, Iron-Deficiency*
;
Iron*
10.Atypical Nodule Arising in a Hepatocellular Adenoma.
Kun Chang SONG ; Young Nyun PARK ; Chanil PARK
Korean Journal of Pathology 1995;29(2):251-255
This report presents a case of an atypical nodule arising in a hepatocellular adenoma(HCA) in a non-cirrhotic liver of a 42-year-old man. The patient had been relatively healthy until he developed right upper abdominal pain. Abdominal sonography and computerized tomogram revealed a 7.5x7cm sized mass in the right inferior segment of liver. The mass revealed the histologic features of HCA. At near center of the HCA, was found a I cm sized discrete nodule, a nodule within a nodule. The nodule revealed higher cellularity than the HCA and was composed of monotonous hepatocytes with an increased nuclear-cytoplasmic ratio, resembling atypical adenomatous hyperplasia. Interestingly, the atypical nodule showed a focal pseudoacinar arrangement of tumor cells. The histologic features of the atypical nodule arising in HCA may the morphological sequence of transformation from HCA to hepatocellular carcinoma
Carcinoma, Hepatocellular