1.Clinicoradiologic evaluation of styloid process calcification.
Mun Bhawni BAGGA ; C Anand KUMAR ; Garima YELURI
Imaging Science in Dentistry 2012;42(3):155-161
PURPOSE: This study was performed to investigate the prevalence, morphology, and calcification pattern of the elongated styloid process in the Mathura population and its relation to gender, age, and mandibular movements. MATERIALS AND METHODS: The study analyzed digital panoramic radiographs of 2,706 adults. The elongated styloid process was classified with the radiographic appearance based on the morphology and calcification pattern. The limits of mandibular protrusion were evaluated for each subject. The data were analyzed by using a Student's t-test and chi-squared test with significance set at p=0.05. RESULTS: Bilateral elongation having an "elongated" type styloid process with a "partially mineralized" pattern was the most frequent type of styloid process. No correlation was found between styloid process type and calcification pattern on the one hand and gender on the other, although elongated styloid was more prevalent in older and male populations (p<0.05). Further styloid process elongation showed no effect on mandibular protrusive movement (p>0.05). CONCLUSION: Dentists should recognize the existence of morphological variation in elongated styloid process or Eagle syndrome apparent on panoramic radiographs. We found higher prevalence of elongated styloid process in the population of the Mathura region when compared with other Indian populations. The calcification of the styloid process was more common in the older age group with no correlation to gender, mandibular movement and site. "Type I" with a "partially calcified" styloid process was observed more frequently in the population studied.
Adult
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Dentists
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Eagles
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Hand
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Humans
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Male
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Ossification, Heterotopic
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Prevalence
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Radiography, Panoramic
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Temporal Bone
2.Use of thiopurines in inflammatory bowel disease: an update
Arshdeep SINGH ; Ramit MAHAJAN ; Saurabh KEDIA ; Amit Kumar DUTTA ; Abhinav ANAND ; Charles N. BERNSTEIN ; Devendra DESAI ; C. Ganesh PAI ; Govind MAKHARIA ; Harsh Vardhan TEVETHIA ; Joyce WY MAK ; Kirandeep KAUR ; Kiran PEDDI ; Mukesh Kumar RANJAN ; Perttu ARKKILA ; Rakesh KOCHHAR ; Rupa BANERJEE ; Saroj Kant SINHA ; Siew Chien NG ; Stephen HANAUER ; Suhang VERMA ; Usha DUTTA ; Vandana MIDHA ; Varun MEHTA ; Vineet AHUJA ; Ajit SOOD
Intestinal Research 2022;20(1):11-30
Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD has come under the spotlight. 5-Aminosalicylates, corticosteroids, immunosuppressive agents and biologics are the backbone of treatment of IBD. With the advent of biologics and small molecules, the need for surgery and hospitalization has decreased. However, economic viability and acceptability is an important determinant of local prescription patterns. Nearly one-third of the patients in West receive biologics as the first/initial therapy. The scenario is different in developing countries where biologics are used only in a small proportion of patients with IBD. Increased risk of reactivation of tuberculosis and high cost of the therapy are limitations to their use. Thiopurines hence become critical for optimal management of patients with IBD in these regions. However, approximately one-third of patients are intolerant or develop adverse effects with their use. This has led to suboptimal use of thiopurines in clinical practice. This review article discusses the clinical aspects of thiopurine use in patients with IBD with the aim of optimizing their use to full therapeutic potential.