1.Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report.
Hyekyung LEE ; Dongwook KANG ; Heejin KIM ; Byungsun CHO ; Jeho JANG
Journal of Pathology and Translational Medicine 2017;51(3):320-324
Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.
CD4-Positive T-Lymphocytes
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Child
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Colon, Descending
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Eosinophils*
;
Female
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Ganglion Cysts*
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Humans
;
Intestinal Pseudo-Obstruction
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Middle Aged
;
Myenteric Plexus