No abstract available.
Hematoma*

No abstract available.
Estradiol* ; Female ; Menstrual Cycle* ; Superovulation*

No abstract available.
Poland Syndrome* ; Poland*

The 5'- and 3'-side half of liver type glucose transporter (GLUT2) cDNA was amplified from total RNA or mRNA by reverse transcriptase-polymerase chain reaction (RT-PCR). The amplified 5'-side fragment of GLUT2 cDNA was inserted into pGEM4Z and named pGLGT1, and the 3'-side fragment of GLUT2 cDNA was inserted into the HindIII site of pGLGT1 to construct pGLGT2 which contains an entire open reading frame of GLUT2 cDNA. The GLUT2 cDNA in pGLGT2 was transferred to an eukaryotic expression vector (pMAM) to construct pMLGT, which was expressed in the insulin-sensitive Chinese hamster ovary (CHO) cells. Western blot analysis showed that the GLUT2 gene in pMLGT was expressed in the transfected CHO cells successfully. The GLUT2 content in the plasma membrane fraction of insulin-treated CHO cells expressing GLUT2 increased 3.8-fold compared to that of the control group. This result suggests that GLUT2, which is not subjected to translocation by insulin in the cells of its major distribution, can be translocated if it is expressed in the suitable cells sensitive to insulin action.
Animal ; Base Sequence ; CHO Cells ; *Cloning, Molecular ; Hamsters ; Insulin/*pharmacology ; Liver/*metabolism ; Molecular Sequence Data ; Monosaccharide Transport Proteins/*genetics/*metabolism ; Oligonucleotide Probes/genetics ; Support, Non-U.S. Gov't ; *Translocation (Genetics)

Endometriosis of the rectum is unusual condition, since it represents an invasion of previously normal bowel by hormone-dependent nonmalignant cell from uterus of the same patient. It is estimated that the incidence of endometriosis is about 8-15% of reproductive women, of whom 3-34% show intestinal invasion of rectosigmoid colon, appendix, ileum, and cecum in order of decreasing frequency. Symptoms related bowel involvement may vary from none to complete intestinal obstruction. Because the mucosa is involved infrequently there is rarely rectal bleeding. X-ray and sigmoidoscopic studies are usually negative. It was not reported that colonic endometriosis was confirmed by endoscopic biopsy. Recently we experienced a case of rectal endometriosis which presented itself as a cyclic rectal bleeding with abdominal pain and diagnosed by colonoscopic biopsy.
Abdominal Pain ; Appendix ; Biopsy* ; Cecum ; Colon ; Colonoscopy ; Endometriosis* ; Female ; Hemorrhage ; Humans ; Ileum ; Incidence ; Intestinal Obstruction ; Mucous Membrane ; Rectum ; Uterus

Peripheral nervous system involvement is common in systemic vasculitis, occurring most frequently in the polyarteritis nodosa (PAN) group of disorders and in rheumatoid vasculitis. Within the polyarteritis nodosa group of systemic necrotizing vasculitides, three subgroups have been described: classic polyarteritis nodosa, Churg-Strauss syndrome, and an overlap syndrome. Three patients with evidence of systemic vasculitis and peripheral neuropathy were clinically and electrophysiologically investigated. All cases presented clinically with mononeuropathy multiples considered typical pattern of ischemic involvement of the peripheral nerve. The causes included polyarteritis nodosa, its Churg-strauss variant, and the overlap syndrome. Pain and weakness were frequent symptoms. Nerve conduction studies were abnormal In all cases. Necrotizing vasculitis was present as pathologic findings in two cases. All patients were treated with prednisolone alone or in combination with other immunosuppressive agents or with plasmapheresis.
Churg-Strauss Syndrome ; Humans ; Immunosuppressive Agents ; Mononeuropathies* ; Neural Conduction ; Peripheral Nerves ; Peripheral Nervous System ; Peripheral Nervous System Diseases ; Plasmapheresis ; Polyarteritis Nodosa ; Prednisolone ; Rheumatoid Vasculitis ; Systemic Vasculitis ; Vasculitis*

Myelography has been generally regarded as a safe procedure. However, epidural hematoma and some allergic reactions have been reported, although rarely, as complications of myelography. Herein, we report a patient who experienced seizure and rhabdomyolysis after iopamidol injection with a review of the pertinent literature. A 75-year-old man with no medical history of seizure underwent lumbar spine myelography for the evaluation of the lumbar spine stenosis. After several hours following injection with water-soluble nonionic contrast medium(Iopamidol), he had a generalized tonic-clonic seizure, which progressed into a complex partial. In spite of the efforts of injecting anti-seizure medications, intermittent short-lasting seizure activity continued for hours and brain computed tomographic scan showed a large amount of hyperdense iopamidol in the subarachnoid space. As a consequence, he suffered from rhabdomyolysis-induced acute renal failure. The patient recovered from the contrast-induced acute renal failure after several days of treatment in the intensive care unit and hemodialysis. Fatal complications, such as seizure and rhabdomyolysis, can occur after myelography. Prompt diagnosis and treatment are needed.
Acute Kidney Injury ; Aged ; Brain ; Constriction, Pathologic ; Hematoma ; Humans ; Hypersensitivity ; Intensive Care Units ; Iopamidol ; Myelography ; Renal Dialysis ; Rhabdomyolysis ; Seizures ; Spine ; Subarachnoid Space

OBJECTIVE: The reaccumulation of hematoma is one of the most frequent problems on the chronic subdural hematoma. The aim of this study is to determine the factors affecting the reaccumulation of hematoma and the reasonable site for the burr-hole trephination to achieve a low reaccumulation rate after burr-hole trephination and closed-system drainage METHODS: The authors studied 93 patients with chronic subdural hematoma in whom the location of burr-hole trephination was randomly placed and precisely determined on postoperative brain computerized tomographic scans or skull roentgenogram. Eighty five patients with chronic subdural hematoma were obtained with brain computerized tomographic scans the postoperative 3 day. The location of the burr-hole trephination, the location of subdural catheter tip, the maximum postoperative width of the subdural space, and the percentage of the ipsilateral subdural space occupied by air postoperatively were measured and analyzed the correlation with the postoperative reaccumulation rates. RESULTS: Patients with the parietal trephination had much more subdural air and a higher of chronic subdural hematoma reaccumulation than those with the frontal one. In addition, patients with residual subdural air on brain computerized tomographic scans obtained the postoperative 3 day also had a higher reaccumulation rate than those without subdural air collections. CONCLUSION: The incidence of postoperative subdural fluid reaccumulation can be reduced by the burr-hole trephination on the frontal convexity and by preventing subdural air accumulation during operation.
Brain ; Catheters ; Drainage* ; Hematoma ; Hematoma, Subdural ; Hematoma, Subdural, Chronic* ; Humans ; Incidence ; Rabeprazole ; Skull ; Subdural Space ; Trephining*

We report a case of meningeal hemangiopericytoma presenting as metastasis in the vertebral body and pedicle of the thoracic spine. Hemangiopericytoma is a rare vascular neoplasm. Although the tumor has a strong propensity for both local recurrence and extracranial metastasis, metastasis to thoracic spine is very rare and only two cases were found in the literature. A 44-year-old woman with paraparesis and pain in the thoracic and lower legs was examined by plain radiographs and magnetic resonance imaging. The intracranial hemangiopericytoma was operated 3 years ago. Magnetic resonance imaging demonstrated a tumor invading the left vertebral body and pedicle of the 11th thoracic spine, and compressing the dural sac. The patient was gradually improved after surgical removal of the lesions and the histologic findings were characteristics of hemangiopericytoma.
Adult ; Female ; Hemangiopericytoma* ; Humans ; Leg ; Magnetic Resonance Imaging ; Neoplasm Metastasis* ; Paraparesis ; Recurrence ; Spine* ; Vascular Neoplasms

OBJECTIVE: About 40% of patients who admit to the hospital after subarachnoid hemorrhage are poor clinical grade(Hunt-Hess grade IV, V). The majority of these patients have been excluded from early, aggressive treatment. The current study was undertaken to evaluate the outcome of urgent surgery for Hunt-Hess grade IV aneurysmal subarachnoid hemorrhage. MATERIALS AND METHODS: We reviewed hospital records and radiographic studies of 36 patients who were Hunt-Hess grade IV among 201 cases with ruptured intracranial aneurysm admitted between Sep. 1995 and Dec. 2000. Operated patients were treated with urgent angiography and surgery within 24 hours of presentation, except six patients, and medical records of these patients were reviewed for the clinical course and Glasgow outcome scale(GOS). RESULTS: Overall management results of the 36 patients were good recovery in 13(36.1%), moderate disability in 12 (33.3%), severe disability in 1(2.8%), vegetative state in 1(2.8%) and 9(25.0%) of surgically treated patients had died. CONCLUSION: Although with limited number of patients, we conclude that urgent surgery for Hunt-Hess grade IV patients results in a better neurologic outcome and urgent surgery combined with aggressive postoperative management can minimize mortality.
Angiography ; Hospital Records ; Humans ; Intracranial Aneurysm* ; Medical Records ; Mortality ; Persistent Vegetative State ; Subarachnoid Hemorrhage