No abstract available.
DiGeorge Syndrome*

Various clinical evaluations in urological aspects were performed on 100 renal transplantations in the Department of Urology, Kosin Medical College from December 1984 to August l988. The following results were obtained. 1. Year distributions were as follows : 1 case was done in 1984, 5 cases in 1986, 31 cases in 1986, 30 cases in 1987, 33 cases in 1988. 2. Of 100 donors 44 cases were male and 56 cases were female. Sixth decade was most common. Of 100 recipients 71 cases were male and 29 cases were female. Fourth decade was must common. 3. Of all living-related donors 89 cases were related donors and 11 cases were unrelated donors. 4. The most common underlying renal disease requiring transplantation was chronic glomerulonephritis (90%) and reflux nephropathy was 2 cases(2 %). 5. All surgical approaches of donor nephrectomy were flank incision, usually with removal of 12th rib(59%). Selected kidney side was follow : 79 cases were left side and 21 cases was right side. 6. The ureteroneocystostomy was performed with modified Politano-Leadbetter method in initial 3 cases and extravesical Mac Kinnon method in 97 cases. 7. Our incidence of urological complications in 100 renal transplantations was 8%(8 cases). 6 cases were ureteral obstructions due to perinephric hematoma, 1 case was ureterotaneous fistula and 1 cases was bladder leakage. 8. Our incidence of complications in 100 donor nephrectomy was 3%(3 cases). 1 case was pleural effusion, 1 case was atelectasis and 1 case was perforation of stomach. 9. Results and prognosis in complicated cases were good.
Female ; Fistula ; Glomerulonephritis ; Hematoma ; Humans ; Incidence ; Kidney ; Kidney Transplantation* ; Male ; Nephrectomy ; Pleural Effusion ; Prognosis ; Pulmonary Atelectasis ; Stomach ; Tissue Donors ; Unrelated Donors ; Ureteral Obstruction ; Urinary Bladder ; Urology

Loss of the urethral floor with total urinary incontinence is a difficult problem that is infrequently encountered by the urologist. The techniques required for the urethral reconstruction are different and can be much more; delicate and demanding than the typical vesicovaginal fistula repair. Herein we report a case of the female urethral loss caused by chemical injury 3 years age and treated using bulbocavernous myocutaneous flap successfully.
Female* ; Humans ; Myocutaneous Flap* ; Urinary Incontinence ; Vesicovaginal Fistula

The horseshoe kidney results from fusion of the two renal blastema at the time when they lie closeset together, usually at the fifth or sixth weeks of intrauterine life and occurs in 0.25% of the general population. Hydronephrosis, infection, calculus formation and concomitant other malformation are associated in the one third of patients. The duplicated ureter occurs in 6 to 10% congenital associated anomalies. This report concerns a case of rare combination of horseshoe kidney, bilateral duplication of ureter with obstruction of one ureteropelvic junction causing symptomatic hydronephrosis due to renal artery of right low moiety, which was treated with heminephrectomy.
Calculi ; Humans ; Hydronephrosis* ; Kidney* ; Renal Artery ; Ureter*

No abstract available.
Humans ; Lung Neoplasms* ; Lung*

For the purpose of investigation to identify the quantities of heavy metals contained in the tissues of the Korean people, a series of analyses was conducted with atomic absorption spectrophotometry to measure the amount of lead, cadmium and copper distributed in various tissues, such as brain, liver, kidney, heart, lung, spleen, large intestine, hair, muscle, fat, stomach, costal cartilage, blood and urine, obtained from 30 cadaverous bodies who were believed not exposed to the said heavy metals during their life time either occupationally or therapeutically. 1. Lead content: Inter-individual difference was noted in lead contents in each tissue, vis., the average content of lead in hair was the highest with 14.90+/-9.74 ppm. The next was in costal cartilage that contained 5.06+/-3.86 ppm. The average contents of lead in liver, kidney and muscle were the lowest in value, showing 1.11+/-0.92 ppm, 0.73+/-0.48 ppm and 0.06+/-0.06 ppm, respectively. The lead contents in tissues of children under the age of 10 were significantly lower than those of adults, and the higher values were shown in finales than in females in general. The lead contents in most of the tissues such as hair, costal cartilage, kidney, lung, fat, stomach, large intestine, heart, muscle and urine were well correlated with age. 2. Cadmium content: The average content of cadmium in kidney appeared to be the highest, of ether tissues showing 20.7+/-29.82 ppm, and liver came nest with the value of 1.17+/-0.99 ppm. It was estimated that 83.9% of the total cadmium absorbed into the body was stored in kidney, 4.7% in liver, and the remaining 11.4% was distributed in the rest of the tissues. Cadmium contents in tissues showed difference between both sexes showing higher values in the females than in the males, which was quite contrary to the lead content. Cadmium contents in tissues steadily increased in amount with age, showing a significant correlation with age in all tissues. 3. Copper content: The average content of copper in hair was the highest with 10.36+/-2.21 ppm, and liver came next with 6.31+/-1.24 ppm. The copper that was absorbed into the body w4s distributed in each tissue: 29.9.% in hair, 18.2% in liver, 5~11% in brain, heart and kidney, and 3.0~3.5% in stomach, blood, and lung. The copper contents in tissues of children under the age of 10 showed significantly higher values in liver, kidney, heart and large intestine than those of the adults. The copper contents in brain, costal cartilage and fat were well correlated with age showing the highest correlation coefficient of 0.870 (p<0.01) in brain tissue. There was no difference in copper contents in tissues between both sexes, and the values were, in general, lower than those for Japanese.
Adult ; Asian Continental Ancestry Group ; Brain ; Cadaver ; Cadmium ; Cartilage ; Child ; Copper ; Ether ; Female ; Hair ; Heart ; Humans ; Intestine, Large ; Kidney ; Liver ; Lung ; Male ; Metals, Heavy* ; Occupations ; Spectrophotometry, Atomic ; Spleen ; Stomach

Intracavernous papaverine injection may be the first step in the assessment of the impotent patient Since measurement of the rigidity requires a sophisticated procedures that may not be available to the majority of the practitioners, we attempted to find an objective method to evaluate the results or this common test. We tested 44 patients complaining of impotence and 2 normal potent men with intracavernous injection of 30mg. papaverine and measured the angle between the penis and the legs with the patient in the standing position and obtained radioisotope erection penogram. Various penogram indexes were calculated from the time activity curve and their usefulness was evaluated and was compared with the findings of nocturnal penile tumescence. The papaverine test can distinguish between the vasculogenic and psychogenic impotent patients. Measurement of the erectile angle after intracavernous injection of papaverine is a simple, objective and reliable method to evaluate patients with vascular impotence. The penogram indexes were significantly correlated with the penile arterial inflow and venous outflow during erection. but not significantly correlated with nocturnal penile tumescence test.
Erectile Dysfunction ; Humans ; Leg ; Male ; Papaverine ; Penile Erection* ; Penis

BACKGROUND: Serum eosinophil cationic protein(ECP) level has been proposed as a indirect marker of eosinophilic inflammation of the airway in bronchial asthma. OBJECTIVE: To evaluate serum ECP against indirect clinical markers of disease, we compared bronchial obstruction, bronchial hyperresponsiveness and peripheral blood eosinophil counts, total IgE with serum ECP levels in patients with bronchial asthma and normal controls. METHOD: Fourty-two patients with bronchial asthma and twenty-six normal controls were enrolled. Measurement were made by spirometry, inhalation challenge with methacholine, peripheral blood eosinophil counts, total IgE and FEIA(fluoroenzymatic immunoassay) of serum ECP RESULT: Serum ECP levels were significantly higher in asthmatic patients than normal controls(p<0.0,5). Serum ECP levels were correlated with peripheral blood eosinophil counts(p<0.01, r=0.544) and bronchial hyperresponsiveness(PC,)(p<0.01, r=-0.456) in patients with bronchial asthma. Serum ECP levels were correlated with degree of bronchial obstruction(FEV, % to predicted value, FEV1/FVC%) in total subjects, but not in asthmatic patients. CONCLUSION: Serum ECP level may be used as indicator of disease activity in bronchial asthma and be helpful in differentiation between normal person and asthmatic patients on simple serological method. Further studies on the changes of serum ECP levels according to disease course and therapeutic responses are needed.
Asthma* ; Biomarkers ; Eosinophil Cationic Protein* ; Eosinophils ; Humans ; Immunoglobulin E ; Inflammation ; Inhalation ; Methacholine Chloride ; Spirometry

Malakoplakia is a very rare disease which affects middle-aged women and usually involves the urinary tract. Of these, the bladder is the most common site and the renal parenchyme is involved in 16%. It is a type of granulomatous inflammation in which the histiocyte contains distinct basophilic inclusion called Michaelis-Gutmann bodies. It may be caused by a defect of phagocytic activity of the lysosome. We experienced a cases of malakoplakia with duplex kidney in a 59-year old female, which was treated successfully with left nephrectomy and antibiotics. Herein we report this case with a brief review of literature.
Anti-Bacterial Agents ; Basophils ; Female ; Histiocytes ; Humans ; Inflammation ; Kidney* ; Lysosomes ; Malacoplakia* ; Middle Aged ; Nephrectomy ; Rare Diseases ; Urinary Bladder ; Urinary Tract

PURPOSE: The purpose of this study was to evaluate the utility of renal CT scanning and to histologicallycorrelate renal damage induced by renal arterial infusion of 0.2 ml/kg of doxorubicin-lipiodol emulsion. MATERIALS AND METHODS: Renal CT scans of 20 rabbit kidneys were obtained 15 days after transcatheter arterialchemoembolization and were classified into four grades, as follows : Grade 0 - no fleck, Grade 1 - one to threenodular flecks ; Grade 2 - four or more nodular flecks, or one semilunar fleck ; and Grade 3 - two or moresemilunar flecks. The percentage of histological section occupied by lesion was determined using squared paper,and compared with the grades determined on the basis of CT. RESULTS: The histologic findings were interstitialinflammatory cell infiltration, intratubular lipiodol droplets, dystrophic calcification, and cellular necrosis.The mean sizes of grade 0, 1, 2 and 3 histological lesions were 2.2%(n=5), 4.5%(n=4), 21.9%(n=7), and 24%(n=4),respectively. Grades 0 and 1 accounted for nine cases(3.2%), while grades 2 and 3 accounted for 11(22.6%) ; thisdifference was statistically significant(p<0.01). CONCLUSION: CT findings showing nodular or semilunar flecks 15days after infusion into the renal artery of doxorubicin-lipiodol emulsion correlate with the size of the damagedkidney, as seen on histological specimens.
Ethiodized Oil ; Kidney ; Renal Artery* ; Tomography, X-Ray Computed