The partial splenectomy was performed on the basis of the arterial distribution in order to reduce complications. The spleen consists of the various histologic components that have different functions. But we can not find the reports whether the distribution of red pulp, white pulp and trabecula is uniform or not according to the regions of the spleen. We used 15 spleens from Korean[male 8, female 7 and age 17-74]. The volume was measured with the mass cylinder. The 1cm3 blocks were selected in 5 different regions. Whole splenic slices by celloidin embedding were made from two spleens. The point counting method with eyepeice reticule was used for the measurement of the distribution of red pulp, white pulp and trabecula. The results were as follows : 1. The volume of the spleen was ranged 45-158ml and the individual difference was marked. The male spleen was larger than female`s [p<0.05]. 2. The ratio of red pulp, white pulp and trabecula of the paraffin embedding preparations was 83.2, 10.9, and 5.9% respectively. There was no significant difference in the distribution of the histologic components among five regions[upper, hilum, middle, outer, and lower]. 3. The distribution of red and white pulps in whole splenic slices was not uniformity. The ratio of red pulp, white pulp and trabecula in whole splenic slices was 80.1, 13.4 and 6.5% respectively. These results showed no significant difference with those of five regions of the spleen.
Collodion ; Female ; Humans ; Individuality ; Male ; Paraffin Embedding ; Spleen* ; Splenectomy

No abstract available.
Epilepsy* ; Occipital Lobe* ; Rabeprazole*

No abstract available.
Cobalt* ; Copper* ; Dental Alloys* ; Nickel*

No abstract available.
Adult* ; Humans

Thirty-five cerebello-pontine angle lesions were diagnosed with simple skull X-ray, CT, and angiography atSeoul National University Hospital from Sept. 1978 through Aug. 1982. The radiographic findings were analysed withemphasis on the differential points of CT among the major three cerebello-pontine angle tumors; acousticneurinoma, meningioma and epidermoid. The results are as follows; 1. Among the 35 cases of cerebello-pontine anglelesions, 19 cases were acoustic neurinoma. 4 cases miningioma, 4 cases epidermoid, 2 cases metastasis, 1 caseschoroid plexus papilloma, 1 case arteriovenous malformation, and 3 cases intra-axial posterior fossa tumors. 2.The characteristic radiographic findings of acoustic neurinoma were windening of internal auditory canal, petrousbone erosion, posterior extension of tumor at the level of internal autidory canal, hypo or isodense mass onpre-contrast CT with high enhancement after intravenous contrast infusion, and cystic change within the mass. 3.Meningioma shows anterior extenstion of the lesion at the level of internal auditory canal, broad base and obtuseangle sign of the lesion with petrous bone, hyperdense mass on precontrast CT. with highly homogeneous enhancementafter intravenous contrast infusion. 4. Epidermoid characteristically shows hypodense mass on precontrast CT withno change after intravenous contrast infusion. 5. The differential points of the major 3 cerebello-pontine tumorswere bone change, mass location, attenuation , degree of attachment to petrous bone, and cystic change.
Angiography ; Arteriovenous Malformations ; Infratentorial Neoplasms ; Meningioma ; Neoplasm Metastasis ; Neuroma, Acoustic ; Papilloma ; Petrous Bone ; Skull

Authors reviewed 21 cases of histologically confirmed rib tumor except metastasis and myeloma from Nov. 1973 to Dec. 1982 at Seoul National University Hospital. The resuls are as follows: 1. Major clinical findings are painand mass. 2. Pathologic diagnosis of rib tumors are 5 cases of fibrous dysplasia, 3 chondroma, 2 osteochondroma, 2desmoplastic fibroma, 3 chondroma, 2 osteochondroma, 2 desmoplastic fibroma, 5 osteosarcoma, 1 aneurysmal bonecyst, 1 eosinophilic granuloma, 1 cavernous hemangioma, 1 chondrosarcoma. 3. Radiologic findings are osteolyticchange and cortical expansion without marginal sclerosis in fibrous dysplasia, central location, well-definedosteolytic change with marginal sclerosis and no cortical destruction in desmoplastic fibroma, corticaldestruction, soft tissue mass and pleural effusion in malignant tumors.
Aneurysm ; Chondroma ; Chondrosarcoma ; Diagnosis ; Eosinophilic Granuloma ; Fibroma ; Fibroma, Desmoplastic ; Hemangioma, Cavernous ; Neoplasm Metastasis ; Osteochondroma ; Osteosarcoma ; Pleural Effusion ; Ribs ; Sclerosis ; Seoul

No abstract available.
Facial Paralysis* ; Humans ; Malocclusion*

PURPOSE:Hypochondroplasia is a skeletal dysplasia characterized by poor childhood growth and an inadequate pubertal growth spurt. Final height attainment of hypochondroplasia has been reported to range between 120 and 152cm. Increased availability of growth hormone with the introduction of recombinant human growth hormone has allowed for clinical trials in a number of growth hormone sufficient children with growth problems. The purpose of this study was to assess the growth promoting effect of human growth hormone in children with hypochondroplasia. METHODS:Five patients with hypochondroplasia diagnosed by clinical and radiological findings between 1993 and 1997 at our hospital was aged 3 and 1/2 -11 and 1/2 years. Each patients continuously received human growth hormone 0.6-0.7U/Kg/week, intramuscularly or subcutaneously in 6-7 divided dose for 2 years. Standard auxologic assessment was carried out every 3 month interval in the first year after commencement of therapy and then same assessment was 6 monthly. Bone age was assessed 6 monthly using Gleurich-Pyle method. RESULTS:Mean height velocity of pretreatment and year 1 and 2 of GH treatment were 3.9+/-0.7, 6.5+/-1.8 and 5.7+/-1.5cm/year, respectively. Mean height standard deviation score for chronological age of pretreatment and year 1 and 2 of GH treatment were -2.7+/-0.3, -2.4+/-0.3 and -2.2+/-0.4, respectively. The increase in the height velocity diminishes over the subsequent year. The increment of bone age after GH treatment were same as the increments of chronological age. CONCLUSION: Short-term GH therapy increases the height velocity of children with hypochondroplasia, but the effect of GH therapy on final height remains unknown.
Child* ; Growth Hormone* ; Human Growth Hormone ; Humans

Glucose-6-phosphate dehydrogenase(G6PD) deficiency is the most common X- linked inherited disorder and is estimated to affect 400 million people worldwide. But the incidence of this disease is very rare in far-east Asia, especially in Korea. Many drugs and infections cause hemolytic anemia in patients with G6PD deficiency. We experienced a case of G6PD deficiency with chronic hepatitis B. The diagnosis was made by clinical symptoms, laboratory data including serologic test and bone marrow findings. We report a case of G6PD with chronic hepatitis with a brief review of related literatures.
Anemia, Hemolytic ; Asia ; Bone Marrow ; Diagnosis ; Glucose-6-Phosphate* ; Glucosephosphate Dehydrogenase Deficiency ; Hepatitis B ; Hepatitis B, Chronic* ; Hepatitis, Chronic* ; Humans ; Incidence ; Korea ; Serologic Tests

Tamoxifen is a nonsteroidal triphenylethylene delivative that has been widely used in the treatment of breast cancer. tamoxifen is indicated for the adjuvant treatment of breast cancer in women following total mastectomy or segmental mastectomy, breast irradiation and chemotherapy. tamoxifen has been shown to have significant benificial effect in the treatment of breast cancer patient as hormonal therapy. However ,there is mounting evidence that tamoxifen may affect other hormon sensitive organs, including the uterus and ovaries. An increased risk of endometrial polyps, endometrial hyperplasia and adenocarcinoma has been reported in tamoxifen treated women. We have met cases of endometrial polyp and endocervical polyp which were associated with tamoxifen use, after modified radical mastectomy for infilterating ductal carcinoma of breast . So we report these cases with the brief review of literatures.
Adenocarcinoma ; Breast ; Breast Neoplasms ; Carcinoma, Ductal ; Drug Therapy ; Endometrial Hyperplasia ; Female ; Humans ; Mastectomy, Modified Radical ; Mastectomy, Segmental ; Mastectomy, Simple ; Ovary ; Polyps* ; Tamoxifen* ; Uterus