No abstract available.
Antibodies, Neutralizing* ; Feces* ; Rotavirus*

BACKGROUND: Neurological syndromes often complicate the management of infective endocarditis. METHODS: We reviewed the neurological complications in 100 patients with infective endocarditis in a tertiary care hospital. RESULTS: Neurological complications occurred in 25 patients (25%). Ischemic infarctions occurred in 15 patients, hemorrhagic infarctions in 5, intracerebral hemorrhages in 12, subarachnoid hemorrhages in 4, and subdural hemorrhages in 2. Brain abscess was detected in 4 and seizures in 2 patients. Staphylococcus aureus endocarditis (p=0.01) and mitral valvular heart disease (p=0.015) correlated statistically with the development of neurological complications. The mortality rate was significantly higher in patients with neurological complications than those without neurological complications (p=0.00). Age, sex, and type of valve (native versus prosthetic) were not related to the complication rate. CONCLUSIONS: We concluded that (1) hemorrhagic complications occurred at a higher rate in this study than previous reports; (2) S.aureus infection and mitral valvular disease predicted the occurrence of neurological complications; and (3) neurological complications were related to mortality rates. (J Korean Neurol Assoc 19(3):202~206, 2001)
Brain Abscess ; Cerebral Hemorrhage ; Endocarditis ; Heart Diseases ; Heart Valve Diseases ; Hematoma, Subdural ; Humans ; Infarction ; Mortality ; Seizures ; Staphylococcus aureus ; Subarachnoid Hemorrhage ; Tertiary Healthcare

No abstract available.
Guillain-Barre Syndrome* ; Pregnancy*

No abstract available.
Animals* ; Corrosion* ; Humans*

BACKGROUND: The effects of intralesional recombinant alpha-2 interferon(IFN) in the treatment of basal cell carcinoma(BCC) and actinic keratosis(AK) would be of value in selected patients. OBJECTIVE: Our purpose is to evaluate the differences of cellular immune reactions between the responded and the unresponded cases treated with IFN. METHODS: We treated five patients with BCC and two patients with AK with the intralesional injection of recombinant alpha-2 IFN. We performed immunohistochemical stainings with paraffin-embedded specimens from the pretreated and posttreated skin lesions. RESULTS: Four patients(three with BCC and one with AK) were healed and three patients showed improvement after treatment. In immunohistochemical stainings, there was an increased number of T cells in the dermal infiltrate of the responded cases but not in the unresponded cases. CONCLUSION: Intralesional IFN may induce T cell-mediated immune response at the site of the tumor by immune modulation.
Actins* ; Carcinoma, Basal Cell* ; Humans ; Injections, Intralesional* ; Interferons* ; Keratosis, Actinic* ; Skin ; T-Lymphocytes

The clinical observation was made on 28 patients with renal cell carcinoma who admitted to the Dept. of Urology, Busan National University Hospital, during the period from January, 1971 to December, 1980. The following results were obtained: 1. Renal Cell carcinoma was more common in male than female and the left kidney than the right, and was most common in the sixth decade. Hematuria was the most common initial symptom and was followed by flank pain and palpable mass. The classic symptom triad of renal cell carcinoma was found in about one fifth of the cases. 2. The abnormal laboratory findings were anemia (50.0%), positive CRP (53.3%), raised a-globulin {46.7%) and raised ESR (35.7%). Metastasis at admission was seen in one fourth of the cases, and the most common site of distant metastasis was the lung. 3. Of 28 cases of renal cell carcinomas, simple nephrectomy was performed on 19, radical nephrectomy on 6, and explorative laparotomy on 3. Of 19 cases of simple nephrectomies, the adjuvant therapy was done on 7.Of 6 cases of radical nephrectomies, the adjuvant therapy was done on 3. 4. Poor prognosis was correlated with palpable mass, raised ESR, and positive CRP. The radical nephrectomy with or without adjuvant therapy was better than simple nephrectomy. 5. The relative survival rate of the patients with the tumors of low stage and low grade was better than that of high stage and high grade. The weight of the tumor was related with prognosis, but the cell type was not.
Anemia ; Busan ; Carcinoma, Renal Cell* ; Female ; Flank Pain ; Hematuria ; Humans ; Kidney ; Laparotomy ; Lung ; Male ; Neoplasm Metastasis ; Nephrectomy ; Prognosis ; Survival Rate ; Urology

From January 1974 to December 1990, 54 patients with stage D2 carcinoma of the prostate. androgen deprivation therapy was initiated in 50 and no treatment in 4. The analyzed prognostic factors were age. urinary retention, bone pain, Karnofsky performance index. serum acid and alkaline phosphatase, anemia. Gleason`s sum, and EOD grading system (new EOD grade and EOD score). The 1. 3 and 5-year survival rates were 66.1 %, 40.1% and 21.6 %, respectively. Mean follow-up was 22 months ranging from 1 to 80 months. Evaluation of response to endocrine therapy in 42 evaluable patients based on NPCP criteria, 6 (15%) showed stabilization of disease with mean duration of 23 months, 8 (19%) partial response with mean duration of 28.4 months and 28 (66%) progression with mean duration of 12.1 months. Forty five patients with bone metastasis who received androgen deprivation therapy had their pretreatment bone scans reviewed using a semi-quantitative grading system based upon the extent of disease (EOD) observed on the bone scan. Using Soloway's 4 grade system, the survival of patients in categories between EOD grade 2 and S didn`t differ from each other. Based on Saitt new EOD 3 grade system, the survival in etch new EOD categories significantly differed from each other (p<0.05). When EOD score system was used employing ALP to overcome the false positive findings and inactive metastatic lesion. the mean survival of patients in EOD score system was improved from 59.8% to 60.4 %. Using the stepwise Cox regression procedure with 7 candidate factors. only two factors (anemia. EOD score) were statistically significant (p<0.1). We conclude anemia and EOD score are two most important prognosticators of the analyzed factors.
Alkaline Phosphatase ; Anemia ; Follow-Up Studies ; Humans ; Neoplasm Metastasis ; Prostate ; Prostatic Neoplasms ; Survival Rate ; Urinary Retention

VUR is usually diagnosed by standard voiding cystourethrography(VCU). However, we are sometimes puzzled not being able to find VUR on VCU in the group of patients in whom VUR is highly suspected from accompanying obvious clinical, urographic and endoscopic features. For the purpose of detecting this type of VUR or 'subclinical VUR, VCU was performed after subcutaneous injection of bethanechol chloride in 3 patients who were highly suspected of VUR and two were diagnosed as subclinical VUR . Case 1 was diagnosed left VUR(grade II ) and case 2 was diagnosed right VUR(grade II) on VCU after' subcutaneous injection of bethanechol chloride. Both underwent unilateral ureteroneocystostomy and are on follow-up. Bethanechol chloride induced voiding cystourethrography is suggested to be a highly method to detect subclinical vesicoureteral reflux.
Bethanechol* ; Follow-Up Studies ; Humans ; Injections, Subcutaneous ; Vesico-Ureteral Reflux*

A clinical observation was made on 10 cases with vesicovaginal fistulas and 5 cases with urethrovaginal fistulas admitted to the Department of Urology, Busan National University Hospital, during the period from January, 1976 to June, 1982. The following results were obtained. 1. The most prevalent age group of vesicovaginal fistula was in its forties to fifties. And that of urethrovaginal fistula was in its thirties to forties and up to twenties. 2. The most common cause of vesicovaginal fistula was total hysterectomy (60%), and that of urethrovaginal fistula was trauma (60%). 3. In 4 of 10 patients with vesicovaginal fistula, the duration between onset and repair of the fistula was 3 to 6 months. In 3 of 5 patients with urethrovaginal fistula, the duration was over 5 years. 4. The most common location of vesicovaginal fistula was the posterior wall of the bladder and that of urethrovaginal fistula was proximal one third of the urethra. 5. The two most common size of vesicovaginal fistula and urethrovaginal fistula were below 1.0 cm and 1.1 to 2.0 cm. 6. The surgical repair was performed in 14 patients. Surgical approaches were as follows; transvaginal in 3, transabdominal in 6 (with vesicovaginal fistula), transvaginal in 5 (with urethrovaginal fistula)patients. 7. The most common duration of catheter drainage in vesicovaginal fistula was 3 wks. And that of urethrovaginal fistula was 2 wks. 8. Vesicovaginal fistula was repaired successfully in 7 out of 9 patients (77.8%), and urethrovaginal fistula was repaired completely in all of 5 patients (100.0%). 9. Postoperative complications of vesicovaginal fistula and urethrovaginal fistula were seen in 3 and 2 patients respectively.
Busan ; Catheters ; Drainage ; Fistula* ; Humans ; Hysterectomy ; Postoperative Complications ; Urethra ; Urinary Bladder ; Urology ; Vesicovaginal Fistula

Methanol poisoning is a rare disease but may cause blindness and, in severe cases, results in death. It may develop lesions in optic nerve and retina, which may be accompanied with permanent visual damage. We report a case of Methanol poisoning in a 20 year-old male patient, which is followed by optic atrophy and loss of vision.
Blindness ; Humans ; Male ; Methanol* ; Optic Atrophy* ; Optic Nerve ; Poisoning* ; Rare Diseases ; Retina ; Young Adult