1.Improvement of titration methods for porcine rotavirus, its serum neutralizing antibody and of virus isolation from feces.
Hyock Jin KWON ; Seok Min YOON ; Rung Kong HA ; Sung Soo CHO ; Ji Byung YOON
Journal of the Korean Society of Virology 1991;21(2):113-117
No abstract available.
Antibodies, Neutralizing*
;
Feces*
;
Rotavirus*
2.Significance of Bethanechol Chloride Induced Voiding Cystourethrography in the Detection of Subclinical Vesicoureteral Reflux.
Kyung Tak SUNG ; Jong Byung YOON
Korean Journal of Urology 1990;31(6):878-882
VUR is usually diagnosed by standard voiding cystourethrography(VCU). However, we are sometimes puzzled not being able to find VUR on VCU in the group of patients in whom VUR is highly suspected from accompanying obvious clinical, urographic and endoscopic features. For the purpose of detecting this type of VUR or 'subclinical VUR, VCU was performed after subcutaneous injection of bethanechol chloride in 3 patients who were highly suspected of VUR and two were diagnosed as subclinical VUR . Case 1 was diagnosed left VUR(grade II ) and case 2 was diagnosed right VUR(grade II) on VCU after' subcutaneous injection of bethanechol chloride. Both underwent unilateral ureteroneocystostomy and are on follow-up. Bethanechol chloride induced voiding cystourethrography is suggested to be a highly method to detect subclinical vesicoureteral reflux.
Bethanechol*
;
Follow-Up Studies
;
Humans
;
Injections, Subcutaneous
;
Vesico-Ureteral Reflux*
3.Pheochromocytoma of the urinary bladder.
Kyung Tak SUNG ; Sun Kyung LEE ; Jong Byung YOON
Korean Journal of Urology 1991;32(5):829-835
No abstract available.
Pheochromocytoma*
;
Urinary Bladder*
4.Treatment results and prognostic factors in advanced carcinoma of the prostate(stage D2).
Jong Byung YOON ; Kyung Tak SUNG
Korean Journal of Urology 1992;33(3):443-452
From January 1974 to December 1990, 54 patients with stage D2 carcinoma of the prostate. androgen deprivation therapy was initiated in 50 and no treatment in 4. The analyzed prognostic factors were age. urinary retention, bone pain, Karnofsky performance index. serum acid and alkaline phosphatase, anemia. Gleason`s sum, and EOD grading system (new EOD grade and EOD score). The 1. 3 and 5-year survival rates were 66.1 %, 40.1% and 21.6 %, respectively. Mean follow-up was 22 months ranging from 1 to 80 months. Evaluation of response to endocrine therapy in 42 evaluable patients based on NPCP criteria, 6 (15%) showed stabilization of disease with mean duration of 23 months, 8 (19%) partial response with mean duration of 28.4 months and 28 (66%) progression with mean duration of 12.1 months. Forty five patients with bone metastasis who received androgen deprivation therapy had their pretreatment bone scans reviewed using a semi-quantitative grading system based upon the extent of disease (EOD) observed on the bone scan. Using Soloway's 4 grade system, the survival of patients in categories between EOD grade 2 and S didn`t differ from each other. Based on Saitt new EOD 3 grade system, the survival in etch new EOD categories significantly differed from each other (p<0.05). When EOD score system was used employing ALP to overcome the false positive findings and inactive metastatic lesion. the mean survival of patients in EOD score system was improved from 59.8% to 60.4 %. Using the stepwise Cox regression procedure with 7 candidate factors. only two factors (anemia. EOD score) were statistically significant (p<0.1). We conclude anemia and EOD score are two most important prognosticators of the analyzed factors.
Alkaline Phosphatase
;
Anemia
;
Follow-Up Studies
;
Humans
;
Neoplasm Metastasis
;
Prostate
;
Prostatic Neoplasms
;
Survival Rate
;
Urinary Retention
5.Neurologic Complications of Infective Endocarditis:Retrospective Review of 100 Cases.
Sung Hun KIM ; Jaseong KOO ; Byung Woo YOON
Journal of the Korean Neurological Association 2001;19(3):202-206
BACKGROUND: Neurological syndromes often complicate the management of infective endocarditis. METHODS: We reviewed the neurological complications in 100 patients with infective endocarditis in a tertiary care hospital. RESULTS: Neurological complications occurred in 25 patients (25%). Ischemic infarctions occurred in 15 patients, hemorrhagic infarctions in 5, intracerebral hemorrhages in 12, subarachnoid hemorrhages in 4, and subdural hemorrhages in 2. Brain abscess was detected in 4 and seizures in 2 patients. Staphylococcus aureus endocarditis (p=0.01) and mitral valvular heart disease (p=0.015) correlated statistically with the development of neurological complications. The mortality rate was significantly higher in patients with neurological complications than those without neurological complications (p=0.00). Age, sex, and type of valve (native versus prosthetic) were not related to the complication rate. CONCLUSIONS: We concluded that (1) hemorrhagic complications occurred at a higher rate in this study than previous reports; (2) S.aureus infection and mitral valvular disease predicted the occurrence of neurological complications; and (3) neurological complications were related to mortality rates. (J Korean Neurol Assoc 19(3):202~206, 2001)
Brain Abscess
;
Cerebral Hemorrhage
;
Endocarditis
;
Heart Diseases
;
Heart Valve Diseases
;
Hematoma, Subdural
;
Humans
;
Infarction
;
Mortality
;
Seizures
;
Staphylococcus aureus
;
Subarachnoid Hemorrhage
;
Tertiary Healthcare
6.A case of Guillain-Barre syndrome in pregnancy.
Cheol Seong BAE ; Jae Yul LEE ; Byung Seog KIM ; Yoon Kee PARK ; Sung Ho LEE
Korean Journal of Perinatology 1992;3(2):93-98
No abstract available.
Guillain-Barre Syndrome*
;
Pregnancy*
7.Basal Cell Carcinoma and Actinic Keratosis Treated with Intralesional Injection of Recombinant Alpha-2 Interferon.
Sung In CHO ; Yoon Whoa CHO ; Chang Kwun HONG ; Kye Yong SONG ; Byung In RO
Annals of Dermatology 1995;7(2):116-120
BACKGROUND: The effects of intralesional recombinant alpha-2 interferon(IFN) in the treatment of basal cell carcinoma(BCC) and actinic keratosis(AK) would be of value in selected patients. OBJECTIVE: Our purpose is to evaluate the differences of cellular immune reactions between the responded and the unresponded cases treated with IFN. METHODS: We treated five patients with BCC and two patients with AK with the intralesional injection of recombinant alpha-2 IFN. We performed immunohistochemical stainings with paraffin-embedded specimens from the pretreated and posttreated skin lesions. RESULTS: Four patients(three with BCC and one with AK) were healed and three patients showed improvement after treatment. In immunohistochemical stainings, there was an increased number of T cells in the dermal infiltrate of the responded cases but not in the unresponded cases. CONCLUSION: Intralesional IFN may induce T cell-mediated immune response at the site of the tumor by immune modulation.
Actins*
;
Carcinoma, Basal Cell*
;
Humans
;
Injections, Intralesional*
;
Interferons*
;
Keratosis, Actinic*
;
Skin
;
T-Lymphocytes
8.Clinical Study on Renal Cell Carcinoma.
Korean Journal of Urology 1982;23(5):610-616
The clinical observation was made on 28 patients with renal cell carcinoma who admitted to the Dept. of Urology, Busan National University Hospital, during the period from January, 1971 to December, 1980. The following results were obtained: 1. Renal Cell carcinoma was more common in male than female and the left kidney than the right, and was most common in the sixth decade. Hematuria was the most common initial symptom and was followed by flank pain and palpable mass. The classic symptom triad of renal cell carcinoma was found in about one fifth of the cases. 2. The abnormal laboratory findings were anemia (50.0%), positive CRP (53.3%), raised a-globulin {46.7%) and raised ESR (35.7%). Metastasis at admission was seen in one fourth of the cases, and the most common site of distant metastasis was the lung. 3. Of 28 cases of renal cell carcinomas, simple nephrectomy was performed on 19, radical nephrectomy on 6, and explorative laparotomy on 3. Of 19 cases of simple nephrectomies, the adjuvant therapy was done on 7.Of 6 cases of radical nephrectomies, the adjuvant therapy was done on 3. 4. Poor prognosis was correlated with palpable mass, raised ESR, and positive CRP. The radical nephrectomy with or without adjuvant therapy was better than simple nephrectomy. 5. The relative survival rate of the patients with the tumors of low stage and low grade was better than that of high stage and high grade. The weight of the tumor was related with prognosis, but the cell type was not.
Anemia
;
Busan
;
Carcinoma, Renal Cell*
;
Female
;
Flank Pain
;
Hematuria
;
Humans
;
Kidney
;
Laparotomy
;
Lung
;
Male
;
Neoplasm Metastasis
;
Nephrectomy
;
Prognosis
;
Survival Rate
;
Urology
9.A case of seronegative enthesopathy and arthropathy syndrome (SEA syndrome).
Il Su KIM ; Jae Yoon KIM ; Byung Su CHO ; Sung Ho CHA ; Chang Il AHN
Journal of the Korean Pediatric Society 1992;35(10):1459-1462
No abstract available.
Rheumatic Diseases*
;
Spondylarthropathies
10.Comparative Studies of the Renal Vasculature of the Human and the Experimental Animals by Renal Microangiography and Corrosion Casts.
Kyung Tak SUNG ; Jong Byung YOON
Korean Journal of Urology 1990;31(4):471-480
No abstract available.
Animals*
;
Corrosion*
;
Humans*