1.Analysis of Parasite-Specific-Antibody Positive Patients for Clonorchis sinensis, Paragonimus westermani, Cysticercus and Sparganum using ELISA.
Sun Hwa LEE ; Mi Na KIM ; Byung Yoon BACK ; Jong Yil CHOI ; Tae Hoon KIM ; Yoo Sung HWANG
The Korean Journal of Laboratory Medicine 2003;23(2):126-131
BACKGROUND: Although human parasitic infestations have decreased generally in Korea, Clonorchis sinensis, Paragonimus westermani, Cysticercus and Sparganum are still a serious concern due to their relatively high prevalence and severe complications. A definitive diagnosis, however cumbersome and occasionally invasive, is required in order to detect adult worms, eggs, or cysts. The parasite-specific IgG antibody (PSA) test using the ELISA method has been recently developed to diagnose and monitor the infestations of those four parasites. We analysed PSA positive patients for Clonorchis sinensis, Paragonimus westermani, Cysticercus and Sparganum. METHODS: The serum samples referred to the Neodin Medical Institute for PSA were tested by the ELISA method using crude extracts of C. sinensis, P. westermani, Sparganum and cystic fluid of Cysticercus. The PSA results during the 7-month period from January to July 2001 were retrospectively analysed. The medical records of the patients at Asan Medical Center (AMC) with positive PSA were reviewed with stool examinations for parasites, skin tests for C. sinensis and P. west-ermani, radiological findings and antiparasitic management. RESULTS: A total of 865 specimens were tested for PSA and 84 samples (9.7%) of 76 patients were positive; C. sinensis, Cysticercus, Sparganum, and P. westermani were positive in 26 patients (3.0%), 26 (3.0%), 14 (1.6%) and 10 (1.2%), respectively. 26 specimens from 18 AMC patients were positive for one or more PSA; 6 Cysticercus. 4 C. sinensis, 5 Sparganum and 3 P. westermani. All PSA-positive cases for Cysticercus, C. sinensis and P. westermani were compatible with the clinical diagnosis; however, it was difficult to elucidate in the clinical correlation of 3 out of 5 Sparganum-positive cases. CONCLUSION: Cysticercus, C. sinensis and P. westermani are currently prevalent in Korea. Positive PSA ELISA tests for Cysticercus, C. sinensis and P. westermani are reliable indicators in diagnosing present infestations among the clinically suspected patients.
Adult
;
Chungcheongnam-do
;
Clonorchis sinensis*
;
Complex Mixtures
;
Cysticercus*
;
Diagnosis
;
Eggs
;
Enzyme-Linked Immunosorbent Assay*
;
Humans
;
Immunoglobulin G
;
Korea
;
Medical Records
;
Ovum
;
Paragonimus westermani*
;
Parasites
;
Prevalence
;
Retrospective Studies
;
Skin Tests
;
Sparganum*
2.Clinical Studies on Emergency Anesthesia for 4,436 Cases.
Young Joon YOON ; Sung Back KO ; Hyun Sup LEE ; Byung Jo CHOI
Korean Journal of Anesthesiology 1979;12(1):61-69
The authors analyzed statistically 4436 cases of emergency anesthesia which were performed at the Department of Anesthesiology, Han-Gang Sung Shim Hospital from Dec. 1971 to Dec. 1976 according to sex, age, department, physical status, anesthetic method, anesthetic agent, anesthetic duration, and mortality. The results were as follows: 1) About forty-five percent of all anesthetic patients were emergency cases. 2) About sixty-three percent of all emergency patients were in the 21 40 age group. 3) The most common disease was appendicitis (996 cases). 4) Halothane was the most commonly used anesthetic agent. .5) Closed or semiclosed circuit absorption anesthesia with endotracheal intubation was mainly employed. 4) Hypotension developed in twelve percent of all emergency anesthesia cases and whole blood was transfused in 1128 cases. 7) Intraoperative and postoperative death occurred in 233 cases, mainly with neurosurgical operations.
Absorption
;
Anesthesia*
;
Anesthesiology
;
Appendicitis
;
Emergencies*
;
Halothane
;
Humans
;
Hypotension
;
Intubation, Intratracheal
;
Mortality
3.A Case of Idiopathic Calcinosis of the Scrotum.
Chung Bum LEE ; Chol Jong BACK ; Byung Ha IN ; Tae Kyoung YUN ; Yoon Bo LEE ; Dae Haeng CHO
Korean Journal of Urology 2001;42(5):553-555
The idiopathic calcinosis of the scrotum is multiple and asymptomatic nodules of scrotal skin which can onset either in childhood or early adulthood. It increases in size and number, while breakingdown to discharge chalky contents on occasions. We report a case of a 68-year-old-man who was effectively treated with a simple excision of the affected skin with an idiopathic scrotal calcinosis. There is no family history of scrotal calcification. Histopathologically, multiple nodules showed the epidermal cyst with partially degenerated wall and calcium deposits with a foreign body reaction in the dermis in this case. In most reported cases, some intact epidermal cysts are also present, and dystrophic calcification, and possible inflammation and rupture of epidermal cysts regarded as be the main pathogenetic mechanism of the disease.
Calcinosis*
;
Calcium
;
Dermis
;
Epidermal Cyst
;
Foreign-Body Reaction
;
Humans
;
Inflammation
;
Rupture
;
Scrotum*
;
Skin
4.Smoking Status and the Related Factors in the Rural Elderly.
Dal Hyun BEAK ; Byung Deog HWANG ; Hyo Jung MOON ; Hee Jung YOON ; Young Doo BACK ; Sung Kook LEE
Journal of Agricultural Medicine & Community Health 2008;33(2):243-254
OBJECTIVE: The purpose of this study was to examine smoking status and the relates factors in the rural elderly. METHODS: This study was conducted with 2,421 elderly people(male 1,273 and female 1,148) residing in the selected 25 villages, and face-to-face interviews with the subjects were made from January 1 through March 30, 2002. RESULTS: The average age of the male subjects was 72.7 and that of the female subjects 72.8. The investigation of smoking states showed that for male subjects, smokers accounted for 49.4%, nonsmokers 26.9%, and abstainers from smoking 23.7% and that for female subjects, smokers accounted for 18.3%, nonsmokers 75.4%, and abstainers from smoking 6.3%. The level of 'low ADL' was significantly higher in abstainers. In men, smoking rate had higher in alone, non-job, queerstreet, 'high ADL'. In women, smoking rate had higher in younger age, queerstreet, unhealthy, 'high ADL'. CONCLUSIONS: The smoking rate of the elderly was relatively high, especially at abstainers. The smoking status of elderly was correlated with age, family type, job, economic status by self-assessment, Self-recognition of health status, ADL level.
Activities of Daily Living
;
Aged
;
Female
;
Humans
;
Male
;
Self-Assessment
;
Smoke
;
Smoking
5.Breast Cancer Screening of 51,170 Women.
Min Hee HUR ; Back Hyun CHO ; Hae Kyung LEE ; Sung Soo KANG ; Kyung Sang LEE ; Byung Jae CHO ; Ja Sung GU ; Sei Ok YOON ; Sung Kong LEE ; Jee Hyun LEE
Journal of the Korean Surgical Society 2002;63(1):11-17
PURPOSE: The purpose of this study was to evaluate the efficacy of annual breast screening, which includes a mammography and a clinical physical examination. METHODS: From April 1995 to March 2000, we performed 51,170 annual clinical examinations and mammographies on 26,354 women, who wanted to undergo breast screening, at the breast center. Ninety-five breast cancers were detected during screening, and of these, only 76 breast cancers were operated on. The result were compared with 650 symptomatic breast cancers from the outpatient department (OPD). RESULTS: Of the 51,170 cases screened, the recall rate for further examination was 9.9% (n=5,066), and the biopsy rate was 2.1% (n=1,096). Ninety-five breast cancers were detected; a detection rate of 0.19%. Fourteen breast cancers were detected after more than 2 screening rounds. On the analysis of the medical audit data based on the screening mammographies, the positive predictive value, confirmed when a biopsy from a surgical consultation was recommended (PPV), was 8.6%. Further, 41 cases involving tumors found at stage 0 or I (54%). There were 25 cases of axillary lymph node metastasis (32.9%). These results were compatible with the ideal rates for medical audits, except for PPV and axillary lymph node metastases. The pathologic stages of the screened group were: 0, 22.4%; I, 31.6%; II, 40.8%; III, 5.2%, whereas those of the OPD group were 0, 3.4%; I, 27.4%; II, 52.8%; III, 15.5%, and IV, 0.8%. Early breast cancers were detected more frequently through screening than by the OPD (P<0.05). Breast conservation surgery was carried out on 32.9% (25 cases) from the screened group, but only 12.8% (83 cases) from the OPD group (P<0.05). CONCLUSION: Our breast cancer screening was properly performed. Further, these findings indicate that breast cancer screening using a clinical examination and a mammography is very effective in the early detection of breast cancer.
Biopsy
;
Breast Neoplasms*
;
Breast*
;
Female
;
Humans
;
Lymph Nodes
;
Mammography
;
Mass Screening*
;
Medical Audit
;
Neoplasm Metastasis
;
Outpatients
;
Physical Examination