No abstract available.
Mesenteric Lymphadenitis* ; Yersinia pseudotuberculosis* ; Yersinia*

No abstract available.
Mesenteric Lymphadenitis* ; Yersinia pseudotuberculosis* ; Yersinia*

It has been over 20 years since the Korean government liberalized overseas travel on January 1989. This liberalization on overseas travel resulted in the rapid growth in Korean outbound travel. The number of overseas travelers hit over one million (Approximately 1,213,000 people) in 1989 and has massively increased up to 10 million in 2007 (Approximately 13,324,000 people in 2007, 11,996,000 people in 2008). Because of an impact of swine flu outbreak on tourism industry, the number of overseas travelers has decreased to nearly 9,494,000 in 2009. However, travel experts expect that this number could bounce back to 11,180,000 in 2010. Not only major social and economic changes, but also the improvement of air transportation that allows non-stop flying up to 16 hours has contributed to steady growth of the overseas travelers. According to data from World Tourism Organization, nearly 880 million international trips were made in 2009 and 50% of them were travels to developing countries. According to another study, 1~5% of travelers required the general medical treatment, and 0.01~0.1% of travelers needed to have an adequate and immediate medical care. The common travel health problems are motion sickness, jet lag, the decreased concentration of oxygen and low air-pressure in aircraft, infectious disease, blood clot embolism, economy class syndrome, random accident, etc. Travelers with chronic diseases such as diabetics, chronic obstructive pulmonary disease, ischemic heart disease, sinusitis disease, liver disease, etc, or those who may require comprehensive medical care should be able to obtain appropriate medical treatment to protect themselves during travel. As the demand of pre/post-travel medical care has grown dramatically, the role of qualified physicians for the safe travel has expanded. To help the patients plan healthy travel, I would like to introduce the most common cases of travel medical care in this paper.
Aircraft ; Chronic Disease ; Communicable Diseases ; Developing Countries ; Diptera ; Embolism ; Humans ; Liver Diseases ; Motion Sickness ; Myocardial Ischemia ; Oxygen ; Pulmonary Disease, Chronic Obstructive ; Sinusitis ; Swine ; Transportation ; Travel Medicine ; Vaccination

BACKGROUND: The purpose of this study was identified the level of knowledge, attitudes on tuberculosis for the foreign students of a domestic university, to develop an prevention educational program designed to improve the level of knowledge, attitudes on tuberculosis. METHODS: This study used a descriptive design in the foreign students of Soonchunhyang University. The participants were 118 foreign students, measurements included a socio-demographic and knowledge, attitudes on tuberculosis. Data were collected from November to December, 2016, with a self-reported questionnaire. The statistical analyses were performed with SPSS version 24.0 software (SPSS Inc, Chicago, IL, USA). RESULTS: The mean scores of knowledge, attitudes on tuberculosis for the foreign students were 16.05 (±4.52), 3.20 (±0.38). The knowledge on tuberculosis for foreign students was significantly different in country (F=11.76, P < 0.001), fatigue (t=2.40, P=0.018), smoking (t=2.45, P=0.016). The attitudes on tuberculosis for foreign students was significantly different in country (F=9.94, P < 0.001), fatigue (t=2.25, P=0.026). In the correlation analysis, the knowledge (r=0.760) positively correlated with the attitudes on tuberculosis for the foreign students (P < 0.001). CONCLUSIONS: These finding indicate that development of educational programs to improve the level of knowledge, attitudes on tuberculosis for the foreign students. Also, future research needed to development the tuberculosis prevention educational programs.
Fatigue ; Humans ; Smoke ; Smoking ; Tuberculosis

BACKGROUND: The purpose of this study was identified the level of knowledge, attitudes on tuberculosis for the foreign students of a domestic university, to develop an prevention educational program designed to improve the level of knowledge, attitudes on tuberculosis. METHODS: This study used a descriptive design in the foreign students of Soonchunhyang University. The participants were 118 foreign students, measurements included a socio-demographic and knowledge, attitudes on tuberculosis. Data were collected from November to December, 2016, with a self-reported questionnaire. The statistical analyses were performed with SPSS version 24.0 software (SPSS Inc, Chicago, IL, USA). RESULTS: The mean scores of knowledge, attitudes on tuberculosis for the foreign students were 16.05 (±4.52), 3.20 (±0.38). The knowledge on tuberculosis for foreign students was significantly different in country (F=11.76, P < 0.001), fatigue (t=2.40, P=0.018), smoking (t=2.45, P=0.016). The attitudes on tuberculosis for foreign students was significantly different in country (F=9.94, P < 0.001), fatigue (t=2.25, P=0.026). In the correlation analysis, the knowledge (r=0.760) positively correlated with the attitudes on tuberculosis for the foreign students (P < 0.001). CONCLUSIONS These finding indicate that development of educational programs to improve the level of knowledge, attitudes on tuberculosis for the foreign students. Also, future research needed to development the tuberculosis prevention educational programs.

OBJECTIVE: In order to investigate more accurate patterns of intrauterine growth in twin fetuses, we constructed the twin-specific growth curve based on gestational age in live-born non-anomalous infants. METHODS: 563 twin pairs, 1,126 infants delivered between January 1994 and October 1999 were comprised our study population. The newborns were grouped according to gestational age and the median, 10th, 50th, and 90th percentile birth weight for each gestational week were calculated. Curves were plotted for the general population and for each gender and parity and compared with previously reported singleton's growth curve. RESULTS: After 32 weeks gestation, birth weight of twins falls below that of singleton, so that by 38 weeks the 50th percentile for twins falls below the singleton 10th percentile. This difference was also present among all subgroups of twins, such as gender and parity. And the mean birth weight in male twin infant was heavier than in female twin infant throughout all gestational week. CONCLUSION: The pattern of growth in twin infants differed from those of singleton. We recommend twin-specific growth curve for clinical use in the management of twin gestations.
Birth Weight ; Female ; Fetus ; Gestational Age* ; Humans ; Infant ; Infant, Newborn ; Male ; Parity ; Pregnancy ; Twins*

BACKGROUND: Recently authentic human growth hormone(hGH) has produced in the E coli K-12, W3110 by recombinant DNA tecbnology in Korea In this paper, the clinical efficacy and immunogenicity of this GH was shdied in 38 children with growth hormone deficiency during therapy of 1 year. METHODS: The subjects of this study were aged 4.9-13.9 years, diagnosed by failure of plasma GH to respond to insulin-induced hypoglycemia, arginine and/or L-dopa loading and height below -2 standard deviation of mean for their chronological age. Each patient received GH 0.5-0.7IU/kg/week subcutaneously in 6-7 divided doses. During treatment, vital signs, height, body weight and bone age were checked every 3 months. Complete blood count, urinalysis, blood chemistry and thyroid hormone were checked before and every 6 months. The measurement of serum IGF-1 level and antibody against hGH were performed before and every 6 months during therapy of I year. RESULT: The height velocities significantly increased from 3.3 +/- 1.5cm/year to 10.1 +/- 2.5 and 9.0 +/- 1.8cm/year at 6 and 12 months of therapy, respectively. The height standard deviation score for chronological age were significantly improved from -2.141.50 to -1.74 +/- 1.43 and -1.54 +/- 1.38 at 6 and 12 months of therapy with increasing ratio of bone age to chronological age from 0.72 +/- 0.15 at pretreatment to 0.76 +/- 0.15 at 6 month, 0.79 +/- 0.16 at 12 month of therapy. The plasma IGF-1 level significantly increased during treatment. One of 36 patients(2.8%) showed positive antibody against hGH after 1 year of treatment. During therapy of 1 year, unwanted and remarkable clinical side effect were not observed in all subjects. CONCLUSION: These results indicate that this E. coli derived authentic recombinant growth hormone is very effective in stimulating linear growth in children with growth hormone deficiency.
Arginine ; Blood Cell Count ; Body Height ; Chemistry ; Child* ; DNA, Recombinant ; Escherichia coli ; Growth Hormone* ; Human Growth Hormone ; Humans* ; Hypoglycemia ; Insulin-Like Growth Factor I ; Korea ; Levodopa ; Plasma ; Thyroid Gland ; Urinalysis ; Vital Signs

An increase in the number of patients with infectious diseases in Korea, can be attributed to various factors, such as the prevalence of new infectious diseases of the 21st century, the re-emergence of past infectious diseases, an increase in the number of elderly individuals, patients with chronic diseases, immune deficiency, and globalization. In this context, vaccination becomes vital for the adult population. Although, the guidelines for adult immunization are currently being updated, the rate of adult vaccination remains lower than that of infant vaccination. At present, the major challenges for increasing the rate of adult immunization include negative views on the need for some immunizations and a lack of understanding of group immunity among the youth. Consequently, a successful immunization program will be required to direct efforts towards educating patients and spreading awareness. Based on the current guidelines and practical applications, varicella zoster; Japanese encephalitis; tetanus, diphtheria, and pertussis; pneumococcus; measles, mumps, and rubella; and hepatitis A vaccines could effectively be considered for adult vaccination.
Adolescent ; Adult ; Aged ; Chickenpox ; Chronic Disease ; Communicable Diseases ; Diphtheria ; Encephalitis, Japanese ; Hepatitis A Vaccines ; Herpes Zoster ; Humans ; Immunization Programs ; Immunization ; Infant ; Internationality ; Korea ; Measles ; Mumps ; Pneumococcal Vaccines ; Prevalence ; Rubella ; Streptococcus pneumoniae ; Tetanus ; Vaccination ; Whooping Cough

Background: This study compared the neutralizing antibody kit using the Enzyme-Linked Immunosorbent Assay (ELISA) method with the rapid antibody diagnostic kit using the Lateral Flow Immunoassay (LFIA) method to evaluate the clinical effectiveness of the COVID-19 Biokit IgG/IgM regarding evaluation of antibody formation after COVID-19 vaccination. Methods: The neutralizing antibody test was performed with antibody detection kit of diagnostic medical devices for the qualitative method using the standard ELISA method. The rapid antibody diagnostic kit was measured with the COVID-19 Biokit IgG/IgM using the LFIA method. Based on the results of the neutralizing antibody measurement test of the standard test method, the test results of the rapid antibody diagnostic kit are compared and analyzed to confirm its the sensitivity and specificity. Results: When the consistency was determined as positive and negative for the two test results, 118 cases were matched and two cases were inconsistent, showing a 98.3% consistency rate. That is, sensitivity 98%, specificity 100% and correctly classified proportion 98%. Conclusions Although the positive results of antibody formation of this kit would mean that individual has immunity to COVID-19, the result cannot be used to confirm or evaluate for re-infection. But the strong agreement between rapid antibody diagnostic kit results and ELISA results suggests that the kit used in this study is available as a screening test for antibody and neutralizing antibody responses, which could help evaluate the need for additional vaccinations, collect data quickly and cheaply and monitor individual immune responses.

An increase in the number of patients with infectious diseases in Korea, can be attributed to various factors, such as the prevalence of new infectious diseases of the 21st century, the re-emergence of past infectious diseases, an increase in the number of elderly individuals, patients with chronic diseases, immune deficiency, and globalization. In this context, vaccination becomes vital for the adult population. Although, the guidelines for adult immunization are currently being updated, the rate of adult vaccination remains lower than that of infant vaccination. At present, the major challenges for increasing the rate of adult immunization include negative views on the need for some immunizations and a lack of understanding of group immunity among the youth. Consequently, a successful immunization program will be required to direct efforts towards educating patients and spreading awareness. Based on the current guidelines and practical applications, varicella zoster; Japanese encephalitis; tetanus, diphtheria, and pertussis; pneumococcus; measles, mumps, and rubella; and hepatitis A vaccines could effectively be considered for adult vaccination.