No abstract available.
Bilirubin* ; Infant, Newborn ; Jaundice, Neonatal*

No abstract available.
Aneurysm* ; Carotid Artery, Internal*

PURPOSE: To analyze serum markers in proximal femur fracture patients, which are known to be accompanied with osteophorosis or metabolic diseases, and consider it as predictive factor and to study how it affects on the fracture form. MATERIALS AND METHODS: Vit. D3 known as serum marker of Vit. D, 25(OH)D, and 1,25(OH)2D of 152 patients from April, 2013 to March, 2014 who visited our hospital and diagnosed as proximal femur fracture(Femur neck fracture 73, Intertrochanteric fracture 79) were analyzed. Also, serum calcium level corrected by serum protein, phosphate, creatinine, alkaline phosphatase, estradiol, IGF-1, and PTH were compared and analyzed. RESULTS: Femur neck fracture group showed significantly low value of D3, 25(OH)D, and 1,25(OH)2D (P-value<0.05) as the values were 37.72+/-7.21 pg/mL, 27.05+/-8.43 ng/mL, 25.05+/-6.78 pg/mL in femur neck fracture group, and 40.36+/-6.97 pg/mL, 29.54+/-9.12 ng/mL, 28.87+/-7.43 pg/mL in intertrochanteric fracture group respectively. The number of patients who were diagnosed as hypovitaminosis D. due to serum 25(OH)D value lower than 30ng/ml were significantly high in femur neck fracture group as the numbers were 56 in femur neck fracture, and 44 in intertrochanteric fracture. Serum calcium level corrected by serum protein, phosphate, creatinine, alkaline phosphatase, estradiol, IGF-1 and PTH level showed no significant difference between two groups. CONCLUSION: Serum 25(OH)D level was decreased in proximal femur fracture patiens, and was lower as the patient was older and BMD was lower. Therefore it is thought that proximal femur fracture is affected by vitamin D metabolism.
Alkaline Phosphatase ; Biomarkers ; Calcium ; Creatinine ; Estradiol ; Femoral Neck Fractures ; Femur ; Humans ; Insulin-Like Growth Factor I ; Metabolic Diseases ; Metabolism ; Neck ; Vitamin D

OBJECTS: Sanjoin, the seeds of Zizyphus vulgaris var. spinosus has been used as the most important hypnotic agent in chinese medicine to treat insomnia. This research was performed in order to examine the effect of betulinic acid and sanjoinine-A which are components of Sanjoin. METHOD: Sleeping time, sleep recordings of EEG, serum serotonin level, and locomotor activity were measured in rats which received betulinic acid and sanjoinine-A as sleep induction material extracted from Sanjoin. RESULTS: 1) Groups received betulinic acid, sanjoinine-A, and lorazepam showed increased sleep time than control group with saline. 2) Groups with betulinic acid, sanjoinine-A, lorazepam and saline recorded beta-wave in sleep recording of EEG. In there was no significant difference among all groups. 3) No significant difference in serum serotonin level among all groups was found. 4) In autonomic activity testing, groups of betulinic acid, sanjoinine-A, and lorazepam showed significantly more decreased in activity than saline group. In comparison of groups of betulinic acid and sanjoinine-A with a group of lorazepam, there was no significant difference. CONCLUSION: These results suggests that betulinic acid and sanjoinine-A have the sedative effect like lorazepam rather than sleep effect.
Animals ; Asian Continental Ancestry Group ; Brain* ; Electroencephalography* ; Humans ; Hypnotics and Sedatives ; Lorazepam ; Motor Activity ; Rats* ; Serotonin* ; Sleep Initiation and Maintenance Disorders ; Ziziphus

Over the past few decades, interest in minimally invasive spine surgery (MISS) has increased tremendously due to its core principle of minimizing approach-related injury while providing outcomes similar to traditional open spine procedures. With technical and technological advancements, MISS has expanded its utility not only to simple spinal stenosis, but also to complex spinal pathologies such as metastasis, trauma, or adult spinal deformity. In this article, we review the techniques and technology in MISS and discuss the indications, benefits, and limitations of MISS.

Objectives: Little is known about the platforms and functionalities of mobile-based personal health record (PHR) applications. The objective of this study was to investigate these two features of PHR systems. Methods: The unit of analysis was general hospitals with more than 100 beds. This study was based on a PHR survey conducted from May 1 to June 30, 2020 and the National Health Insurance administrative data as of March 31, 2020. The study considered the platform, Android and iPhone operation system (iOS), and types of functionalities of PHR systems. Among the 316 target hospitals, 103 hospitals had adopted PHR systems. A logistic regression analysis was used. Results: This study found that 103 hospitals had adopted mobile-based PHR systems for their patients. Sixty-four hospitals (62.1%) were adopting both Android and iOS, but 36 (35.0%) and 3 (2.9%) hospitals were adopting Android only or iOS only, respectively. The PHR systems of hospitals adopting both platforms were more likely to have functions for viewing prescriptions, clinical diagnostic test results, and upcoming appointment status compared to those adopting a single platform (p < 0.001). The number of beds (odds ratio [OR] = 1.004; confidence interval [CI], 1.001–1.007; p = 0.0029) and the number of computed tomography systems (CTs) per 100 beds (OR = 6.350; CI, 1.006–40.084; p = 0.0493) were significantly associated with the adoption of both platforms. Conclusions More than 60% of hospitals had adopted both Android and iOS platforms for their patients in Korea. Hospitals adopting both platforms had additional functionalities and significant association with the number of beds and CTs.

PURPOSE: Pancretojejunostomy leakage is the most dreaded complication after a pancratoduodenectomy. However, little is known about what causes the leakage and how to prevent it. The aim of this study was to dentify the risk factors for pancreatic leakage. This paper describes our experience of its management. METHODS: Between Aug. 1996 and Aug. 2003, 75 consecutive patients with periampullary cancer or benign disease received a pancreatoduodenectomy. The patients' clinical characterisitcs, pathological features and surgical findings were retrospectively evaluated. The patients were classified into those with major complication and rhose with no complications and the risk factors were analyzed. Pancreatic leakage, intraabdomnial fluid collection and abscess, intraabdomnial bleeding were categorized as major complications related to a pancreatic fistula. RESULTS: The postoperative mortality and morbidity rate was 2.6% and 36%, respectively. Univariate analysis showed that the pancreatic texture, pathologic diagnoses and comorbidity were significant risk factors for major complications (P= 0.003, 0.045, 0.02). Multivariate analyses revealed that the, pancreatic texture was the only significant risk factor (P=0.003). The preoperative serum albumin level and pancreatic texture were significant risk factors for pancreatic leakage (p=0.03, 0.025) and multivariate analysis showed that the pancreatic texture was also the most significant risk factor. CONCLUSION: Considering that the pancreatic texture is the most significant risk factor for a pancreatic fistula, the technical skill and experience of the surgeon appears to be important for its prevention.
Abscess ; Comorbidity ; Diagnosis ; Hemorrhage ; Humans ; Mortality ; Multivariate Analysis ; Pancreatic Fistula* ; Pancreaticoduodenectomy ; Retrospective Studies ; Risk Factors* ; Serum Albumin

A retrospective analysis of 219 mild head injured patients who were admitted to Chung-Ang University Hospital from January 1990 to December 1991 was made to correlate outcome to initial Glasgow coma scale(GCS) score, combined injuries and radiologic findings. The results were as follows: 1) The young males were most frequently affected. 2) The most common cause was motor vehicle accident followed by fall. 3) The most common combined injury was cervical sprain followed by subgaleal hematoma. 4) The skull fractures were shown in 29.2% but there was no correlation between outcome and skull fracture. 5) The most common abnormal CT finding was the subdural hematoma(20.3%). 6) The positive blood alcohol test was not correlated with the outcome. 7) The majority of the patients(91.8%) made a good recovery. 8) Thirteen patients(5.9%) were performed cranial operation under the diagnosis of epidural hematoma(5 patients), subdural hematoma(4 patients), contusion and FCCD.
Coma ; Contusions ; Craniocerebral Trauma* ; Diagnosis ; Glasgow Coma Scale ; Glasgow Outcome Scale ; Head* ; Hematoma ; Humans ; Male ; Motor Vehicles ; Prognosis ; Retrospective Studies ; Skull Fractures ; Sprains and Strains

PURPOSE: To review the treatment outcomes of patients with limited-stage small-cell lung cancer (LS-SCLC) receiving daily thoracic irradiation (RT) to > or = 60 Gy. Materials and M ethods: The records of patients treated with RT for LS-SCLC between 1990 and 2002 at Pusan National University Hospital were retrospectively reviewed. Fifty-six patients were identified who had received once-daily 1.8~2 Gy fractions from 40 Gy to 63 Gy. All patients received sequential chemotherapy and then RT. These patients were arbitrary divided two groups according to thoracic radiation dose, <60 Gy and > or =60 Gy. The time to death was assessed using actuarial method. RESULTS: Two- and 5-year overall survival rates for <60 Gy and > or =60 Gy group was 32% and 41% and 14% and 21%, respectively (p=1.6). Median overall survival for <60 Gy group and > or =60 Gy group was 17 and 20 months, respectively. Two case of acute Grade 3 esophagitis and one case of acute Grade 4 pneumonitis developed in > or =60 Gy group. The first relapse sites of chest for <60 Gy group and > or =60 Gy group were 9/15 (60%) and 3/8 (38%), respectively (p=0.4). CONCLUSION: > or =60 Gy once-daily thoracic radiotherapy was generally well tolerated and moderately improves local control compared to <60 Gy in patients with LS_ SCLC who are treated with combination chemotherapy
Busan ; Chemoradiotherapy ; Drug Therapy ; Drug Therapy, Combination ; Esophagitis ; Humans ; Lung Neoplasms* ; Lung* ; Pneumonia ; Radiotherapy ; Recurrence ; Retrospective Studies ; Survival Rate ; Thorax

Pseudoaneurysm is one of the undesirable complications of interventional cardiology procedures involving peripheral puncture site. Nowadays, it is not uncommon as a consequences of more complex interventional preocedures, larger catheters and prolonged anticoagulation treatment. Surgical repair has been mainstay of treatment for pesudoaneurysm. However, sucessful closures of pseudoaneurysms have been reported recently by using direct compression guided by color doppler ultrasound. We report a case of pseudoaneurysm in femoral artery, which was developed at the right inguinal puncture site in 38 year old male patient with unstabel angina who had received continuous intravenous infusion of heparin and had undergone coronary angiography treated successfully with direct compression guided by color doppler ultrasound.
Adult ; Aneurysm, False* ; Cardiology ; Catheters ; Coronary Angiography ; Femoral Artery* ; Heparin ; Humans ; Infusions, Intravenous ; Male ; Punctures ; Ultrasonography*