2.Study on the lead exposure of workers in a litharge making industry.
Sang Bok LIM ; Jung Kyu LIM ; Sung Soo LEE ; Kyu Dong AHN ; Byung Kook LEE
Korean Journal of Preventive Medicine 1995;28(4):875-884
In order to investigate the level of lead exposure of workers in litharge making industry and to evaluate how lead exposure, personal habit such as smoking and drinking affect the prevalence of lead related symptoms and other study variables, we investigate 114 workers(24 office workers and 90 lead exposed workers) in a litharge making industry. Study variables chosen were blood lead(PbB), zinc protoporphyrin in whole blood(ZPP), Hemoglobin(Hb), hematocrit (Hct), SGOT and SGPT. symptom questionnaires which had 15 lead exposure related symptoms were provided to all workers and filled up by themselves and reconfirmed by physician. The results obtained were as follows; 1. The mean value of PbB, ZPP and SGOT in lead exposed group were higher than those of non-exposed group, and there were no differences of means in other study variables. 2. The smoking and drinking rate of study subjects were 65.8% and 71.0% as a whole. Smoking rates were lower in non-exposed group than exposed group, but drinking rate were not. 3. There were no differences of mean values of study variables between smoker and non-smoker in non-exposed and exposed group, but there was a difference of mean value of SGOT between drinker and non-drinker in lead exposed group. 4. while the symptom prevalence of lead exposed group were higher in neuromuscular category than non-exposed group, those of non-exposed group were higher or same with exposed group in gastrointestinal and general symptom category. 5. The symptom prevalence of smoker were higher than non-smoker regardless of exposure. 6. The symptom prevalence of drinker were only higher in gastrointestinal symptom category than non-drinker. 7. In multiple stepwise regression analysis of lead related symptoms as dependent variable and blood lead, smoking habit, drinking habit and work duration as independent variables, drinking habit contributed to the gastrointestinal symptom category, whereas blood lead and smoking contributed to the neuromuscular symptom category. For the total symptoms work duration and smoking habit contributed significantly.
Alanine Transaminase
;
Aspartate Aminotransferases
;
Drinking
;
Hematocrit
;
Humans
;
Prevalence
;
Surveys and Questionnaires
;
Smoke
;
Smoking
;
Zinc
3.A large well marginated round mass containing calcification.
Byung Sung LIM ; Dong Ho SHIN ; Sung Soo PARK ; Jung Hee LEE
Tuberculosis and Respiratory Diseases 1991;38(2):207-211
No abstract available.
4.A Clinical Study of Kawasaki Disease Complicating Coronary Aneurysm.
Chong Sung CHUNG ; Byung Yul LIM ; Sung Ho CHA ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1989;32(9):1240-1247
No abstract available.
Coronary Aneurysm*
;
Mucocutaneous Lymph Node Syndrome*
5.A Clinical Study on Fatal Cases within 30 Days Following Surgery.
Choon Hak LIM ; Hye Ja LIM ; Hae Weon LEE ; Byung Kook CHAE ; Nan Sook KIM ; Sung Ho CHANG
Korean Journal of Anesthesiology 1997;33(1):147-153
BACKGROUND: A retrospective study was performed to evaluate postoperative mortality within 30 days following surgery. METHODS: The records of 31,806 patients who received operation under general anesthesia were reviewed. RESULTS: 1) Postoperative deaths were 184 cases, the ratio of which was comprising 0.57% of all surgical operative cases. 2) The highest ratio of the mortality in age group was 51~60 years group which was 24.5%, and in physical status it was ASA class III which was 36.4%. The highest ratio to the mortality rate in postoperative days was 8~30 days which was 45.1%. 3) The most common causes of death was low cardiac output due to heart failure on operating theater, and hypovolemic shock within postoperative 2 days, and intracranial problem within postoperative 7 days, and pulmonary complication within postoperative 30 days. CONCLUSION: We conclude that fatality rate could be decreased by intensive and multidisciplinary care for postoperaive complications as respiratory and renal failure.
Anesthesia, General
;
Cardiac Output, Low
;
Cause of Death
;
Heart Failure
;
Humans
;
Mortality
;
Renal Insufficiency
;
Retrospective Studies
;
Shock
6.Prevalence of Osteoporosis, Related Factors in 66-Year-Old Women in Korea.
Byung Sung KIM ; Hae Won LIM ; Chang Won WON ; Hyun Rim CHOI
Korean Journal of Health Promotion 2012;12(3):109-114
BACKGROUND: With the rapid increase in the elderly population and the ensuing increase in osteoporosis and subsequent fractures, there has been a rise in socioeconomic costs. This study evaluated the relationship between osteoporosis and physical function in 66-year-old Korean women. METHODS: All of the 193 Korean women aged 66 years were recruited from life-transition health examinations from May to December, 2007. Background information was collected through a self-administered questionnaire; and height, weight, and waist circumference were measured. Bone mineral density of the lumbar spine was measured with the Dual Energy X-ray Absorptiometry and the 'timed up and go (TUG)' and 'one-leg balance (OLB)' tests were administered. Risk factors for osteoporosis were analyzed by correlation coefficients and binary logistic regression analysis. RESULTS: The prevalence of osteoporosis for 66-year-old women was 25.9%. A short stature and lower body mass index (BMI) were associated with osteoporosis of the lumbar spine. A longer time to complete the TUG test (>10 second) was associated with a 4-time higher prevalence of lumbar osteoporosis, which was not observed with the OLB test. CONCLUSIONS: One out of four 66-year-old Korean women had osteoporosis. A longer TUG time, short stature, and lower BMI were associated with osteoporosis.
Absorptiometry, Photon
;
Aged
;
Body Mass Index
;
Bone Density
;
Female
;
Humans
;
Korea
;
Logistic Models
;
Osteoporosis
;
Prevalence
;
Risk Factors
;
Spine
;
Waist Circumference
7.Epidermoid Tumor of Posterior Fossa : Analysis of 10 Cases.
Hyo Joo LIM ; Jae Sung AHN ; Yang KWON ; Jung Kyo LEE ; Byung Duk KWUN
Journal of Korean Neurosurgical Society 2000;29(6):744-747
No abstract available.
8.Bile duct changes in rats reinfected with Clonorchis sinensis.
Dongil CHOI ; Sung Tae HONG ; Shunyu LI ; Byung Suk CHUNG ; Jae Hoon LIM ; Soon Hyung LEE
The Korean Journal of Parasitology 2004;42(1):7-17
This study describes an evaluation of the sonographic, cholangiographic, pathological, and immunological findings, and the protective effect shown by rats reinfected with Clonorchis sinensis. Eight experimental rat groups were, namely, a normal control, a primary infection control, a reinfection I (reinfection 7 week after treatment following 3-week infection), a reinfection II (reinfection 2 week after treatment following 8-week infection), a reinfection III (exploration of the intrahepatic bile ducts 1 week after reinfection 4 week after treatment following 4-week infection), a superinfection, a secondary infection control, and an infection following immunization group. Sonographic and cholangiographic findings showed moderate or marked dilatation of the bile duct confluence in the primary infection control, reinfection II, and secondary infection control groups. Juvenile worms survived in the intrahepatic bile ducts 1 week after reinfection following treatment in the reinfection III group. It was concluded that reinfecting juvenile worms found during the first week following reinfection failed to survive or grow further. Anatomical, pathophysiological, or immunological changes may induce protection from reinfection in rats.
Animals
;
Anthelmintics/administration & dosage/therapeutic use
;
Antibodies, Helminth/blood
;
Antigens, Helminth/administration & dosage/immunology
;
Bile Duct Diseases/parasitology/*pathology/ultrasonography
;
Bile Ducts, Intrahepatic/parasitology/*pathology/ultrasonography
;
Cholangiography
;
Clonorchiasis/parasitology/*pathology/ultrasonography
;
Clonorchis sinensis/*pathogenicity
;
Immunization
;
Praziquantel/administration & dosage/therapeutic use
;
Rats
;
Rats, Sprague-Dawley
;
Sound Spectrography
;
Support, Non-U.S. Gov't
9.Total Protein and Paper Electrophoretic Fractions of the Serum of Syphilitic Patients.
Korean Journal of Urology 1967;8(1):9-15
Many reports have been found in the literature regarding the electrophoretic study of various urogenital diseases, but those on syphilis are relatively rare. It is author's opinion that the correlation between syphilis and the dysfunction of various organs must also be elucidated into detail. On this view point the author has studied the total protein and paper electrophoretic fractions of the serum derived from the patients of syphilis in 17 males and 5 females visited our department during the period from October, 1962 to September, 1964 Age distribution was between 18 and 45 years of age and duration of history was from 3 months to 8 months. The results obtained were as follows: 1. Total protein and electrophoretic fractions of 22 patients' serum: a) The amount of total protein decreased slightly. b) Albumin decreased markedly. c) Alpha 1 globulin decreased remarkably. d) Alpha 2 globulin decreased slightly. e) Beta globulin increased very remarkably. f) Gamma globulin increased markedly. g) A/G ratio decreased very remarkably. All of the above patterns were compared with normal rate. 2. Total protein and electrophoretic fractions of same 22 patients' serum in duration 30 days after complete therapy: a) The amount of total protein, albumin alpha 2 globulin, gamma globulin and A/G ratio etc. are unchanged b) Alpha 1 globulin decreased markedly. c) Beta globulin increased slightly. All of the above pattern were compared with normal rate.
Age Distribution
;
Beta-Globulins
;
Electrophoresis, Paper
;
Female
;
gamma-Globulins
;
Humans
;
Male
;
Syphilis
10.Effects of Inhalational Anesthetics on Contractile Responses and Nitric Oxide Synthase Activity in Endotoxemic Rats.
Jin Woong PARK ; Dong Geon LIM ; Sung Sik PARK ; Byung Young CHOI ; In Kyeom KIM
Korean Journal of Anesthesiology 1997;33(2):204-214
BACKGROUND: Recent studies revealed that inhalational anesthetics (IA) attenuate NO production. But the hemodynamic changes produced by IA in septic syndrome patient are still sufficient to threaten patient, surgeon and anesthesiologist. So we examined which IA is proper to maintain vascular contractile force and evaluated the effects of NOS inhibitors on contractile force of septic rat aorta under IA. METHODS: Aortic ring preparation was obtained from LPS-treated (1.5 mg/kg, i.p. for 18h) rats. The development of sepsis was confirmed by iNOS activity and iNOS expression using RT-PCR. Contractile responses of aorta to phenylephrine admministation in the presence or absence of halothane, enflurane and isoflurane were evaluated. We also evaluated the effects of NOS inhibitors, one is NG-nitro-L-arginine methyl ester (L-NAME) and the other is aminoguanidine. Statistical significances (p<0.05) were analyzed according to data characteristics by unpaired t-test and paired t-test. RESULTS: The contractile responses to phenylephrine admministration were attenuated in LPS-treated rings. Isoflurane, even at the dose of 2 MAC, didn't affect the contractile response while both halothane and enflurane decreased the contractile response even at the dose of 1 MAC. The potentiation of contractile responses by NOS inhibitors were not affected during administeration of IA. CONCLUSIONS: From these results, it is suggested that isoflurane is the safest inhalational anesthetic and NOS inhibitors, especially L-NAME, may be very useful in the therapy of septic shock patients during general anesthesia.
Anesthesia, General
;
Anesthetics*
;
Animals
;
Aorta
;
Enflurane
;
Halothane
;
Hemodynamics
;
Humans
;
Isoflurane
;
NG-Nitroarginine Methyl Ester
;
Nitric Oxide Synthase*
;
Nitric Oxide*
;
Phenylephrine
;
Rats*
;
Sepsis
;
Shock, Septic