1.Role of Redistribution and 24 Hour Reinjection Images to assess Myocardial Viability in Patients with Acute Myocardial Infarction.
Seok Nam YOON ; Moon Sun PAI ; Chan H PARK ; Myung Ho YOON ; Byung Il CHOI
Korean Journal of Nuclear Medicine 1998;32(4):325-331
PURPOSE: We evaluated the importance of redistribution and 24 hour reinjection images in Tl-201 SPECT assessment of myocardial viability after acute myocardial infarction (AMI). MATERIALS AND METHODS: We performed dipyridamole stress-4 hour redistribution-24 hour reinjection Tl-201 SPECT in 43 patients with recent AMI (4-16 days). The myocardium was divided into 16 segments and perfusion grade was measured visually with 4 point score from 0 to 3 (absent uptake to normal uptake). A perfusion defect with stress score 2 was considered moderate. A defect was considered severe if the stress score was 0 or l (absent uptake or severe perfusion decrease). Moderate defect on stress image were considered viable and segments with severe defect were considered viable if they showed improvement of 1 score or more on redistribution or reinjection images. We compared the results of viability assess-ment in stress-redistribution and stress-reinjection images. RESULTS: On visual analysis, 344 of 688 segments (50%) had abnormal perfusion. Fifty two (15%) had moderate perfusion defects and 292 (85%) had severe perfusion defects on stress image. Of 292 severe stress defects, 53 were irreversible on redistribution and reversible on reinjection images, and 15 were reversible on redistribution and irreversible on reinjection images. Two hundred twenty four of 292 segments (76.7%) showed concordant results on stress-redistribution and stress-reinjection images. Therefore 24 hour reinjection image changed viability status from necrotic to viable in 53 segments of 292 severe stress defect (18%). However, myocardial viability was underestimated in only 5% (15/292) of severe defects by 24 hour reinjection. CONCLUSION: The 24 hour reinjection imaging is useful in the assessment of rnyocardial viability. It is more sensitive than 4 hour redistribution imaging. However, both redistribution and reinjection images are needed since they complement each other.
Complement System Proteins
;
Dipyridamole
;
Humans
;
Myocardial Infarction*
;
Myocardium
;
Perfusion
;
Tomography, Emission-Computed, Single-Photon
2.Pheochromocytoma of the urinary bladder.
Kyung Tak SUNG ; Sun Kyung LEE ; Jong Byung YOON
Korean Journal of Urology 1991;32(5):829-835
No abstract available.
Pheochromocytoma*
;
Urinary Bladder*
3.A histologic study of initial change and repair of tooth and periodontal tissue in extrusion of young adult dogs.
Byung Sun YOON ; Kyung Suk CHA ; Jin Woo LEE
Korean Journal of Orthodontics 1998;28(3):419-429
This study was carried out in order to study early histologic changes and repair reaction appling to extrusive force for 3rd premolar of adult dogs. After 1 week of extrusive force with elastic chain, one of dogs was sacrified and after 3 weeks retention period, another dog was sacrified. The paraffin sections of samples were stained with Hematoxylin - Eosin and Masson's Trichrome and were examed by light microscopy . The obtained results as follows. 1, In Hematoxylin - Eosin and Masson Trichrome stain of control group , the periodontal ligament width was constant from apical third to cervical third of the root and periodontal fiber arrangement was horizontal or oblique in cervical third, oblique in middle third, oblique in apical third of root. in alveolar bone, smooth appearance was shown. 2. In Group 1, all periodontal fiber arrangement was oblique toward tooth, and the periodontal ligament width increased . Partially PDL was ruptured in apex. In MT stain, immature bone formation was seen at alveolar crest area. Active bone formation was observed along the one side of alveolus, and apical portion of pulp was involved with blood vessel rupture , vacuolization of pulp tissue and hyperemia. 3. In Group 2, most periodontal ligament arrangement and PDL width was repaired and fiber density increased In MT stain, mineralization of immatuie bone on the alveolar crest was progressed. In pulp, vacuole and hyperemia was diminished and fibrotic change was diminished. 4. After 3 week periodontal ligament has more repair ability than pulp tissue. pulp was involved with vacuolization and fibrosis, so it takes more time for repair.
Adult
;
Animals
;
Bicuspid
;
Blood Vessels
;
Dogs*
;
Eosine Yellowish-(YS)
;
Fibrosis
;
Hematoxylin
;
Humans
;
Hyperemia
;
Microscopy
;
Osteogenesis
;
Paraffin
;
Periodontal Ligament
;
Rupture
;
Tooth*
;
Vacuoles
;
Young Adult*
4.Scalp Extender for Hair Replacement Surgery and Treatment of Male Pattern Baldness.
Eul Sik YOON ; Sang Whan KOO ; Seung Ha PARK ; Duck Sun AHN ; Byung Kyu SOHN
Journal of the Korean Society of Aesthetic Plastic Surgery 1998;4(1):5-14
Scalp extension involves the continuous nonvolumetric expansion of the hair-bearing scalp, via biologic creep, using implanted surgical device consists of cutting a 5 cm wide strip of plain silastic (0.02 inch thick) from a larger 16x8 inch sheet, then gluing dacron-reinforced silastic strip (5x1 cm, 0.015 inch thich) to the distal ends. A stainless steel plate from hooks is then secured to each end of the extender. During the period from March 1996 to September 1997, 21 patients including 16 patients of male pattern baldness were treated for alopecia of the scalp using internal scalp extender in the department of plastic surgery Korea university hospital. All cases were successfully reconstructed without major complications. It not only reduces the number of scalp reductions and time necessary to totally excise bald vertex scalp, but also appears to decrease the amounts of stretch back and atrophic scarring that may accompany some reductions. Scalp extension appears to be a useful adjunctive technique in hair replacement and reconstructive surgery, and has distinct advantages over standard scalp reduction and tissue expansion techniques.
Alopecia*
;
Cicatrix
;
Hair*
;
Humans
;
Korea
;
Male*
;
Scalp*
;
Stainless Steel
;
Surgery, Plastic
;
Tissue Expansion
5.10 cases of malignancies after allograft kidney transplantation.
Dong Chan JIN ; Young Suk YOON ; Sun Ae YOON ; Yong Soo KIM ; Byung Kee BANG ; Yong Bok KOH
Korean Journal of Nephrology 1993;12(3):420-425
No abstract available.
Allografts*
;
Kidney Transplantation*
;
Kidney*
6.A nocardial infection in the renal transplant recipient.
Chang Ki MIN ; Dong Chan JIN ; Sun Ae YOON ; Yong Soo KIM ; Young Suk YOON ; Byung Kee BANG
The Journal of the Korean Society for Transplantation 1992;6(1):55-59
No abstract available.
Transplantation*
7.Clinical study on cesarean hysterectomy.
Sang Yoon JUNG ; Hyung Woo RYU ; Byung Tae LEE ; Moon Su KIM ; Young In KIM ; Yoon Sun LEE ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1991;34(2):209-215
No abstract available.
Hysterectomy*
8.Clinical study on cesarean hysterectomy.
Sang Yoon JUNG ; Hyung Woo RYU ; Byung Tae LEE ; Moon Su KIM ; Young In KIM ; Yoon Sun LEE ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1991;34(2):209-215
No abstract available.
Hysterectomy*
9.Clinical Study of a Laparoscopic Cholecystectomy after a Percutaneous Cholecystostomy.
Jae Yoon LEE ; Byung Sun CHO ; Yoe Dae YOON ; Yoon Jung KANG ; Ju Seung PARK
Journal of the Korean Surgical Society 1999;56(1):112-116
BACKGROUND: A laparoscopic cholecystectomy has many clinical advantages and is now recognize as the choice for treatment for gallstones. However a laparoscopic cholecystectomy is often not feasible or is converted to the conventional open method in patients with acute cholecystitis because of surrounding adhesion, tissue edema, and high postoperative complications. Lately, good clinical results have been reported by many authors for a percutaneous cholecystostomy followed by a laparoscopic cholecystectomy in the management of acute cholecystitis. METHODS: Between January 1996 and March 1997, 56 acute cholecystitis patients were surgically treated in our institution. Thirteen patients underwent percutaneous drainage followed by a laparoscopic cholecystectomy (Group I). Also a laparoscopic cholecystectomy without a prior percutaneous cholecystostomy was attempted in 43 patients (Group II). RESULTS: There were no differences in the age and the sex distributions, the chief complaints on admission, and the severity of inflammation between the two groups. The only significant difference was the wall thickness of the gallbladder on postoperative pathologic examinations, 4.7 mm for Group I and 6.2 mm Group II (p=0.038). For the patients in Group I, percutaneous drainage of the gallbladder continued for 5.4 days on average, and the cholecystectomy was usually performed about 15 days later. A laparoscopic cholecystectomy was possible in 10 patients (76%) in Group I, but had to be converted to the open method in 3 patients. In Group II, only 17 patients (39.5%) out of 43 underwent a successful laparoscopic cholecystectomy. In other words, the open conversion rate was 24% in Group I and 60.5% in Group II. The wall thicknesses of the gallbladder excised laparoscopically were 3.98 mm and those of the conventionally removed gallbladder were 6.96 mm on average. This difference in the wall thickness was statistically significant (p=0.013) and was the only factor related with the open conversion rate. CONCLUSIONS: We think that a laparoscopic cholecystectomy performed several days after percutaneous drainage of the gallbladder to eliminate acute inflammation may be recommended for management of acute cholecystitis patients with severe clinical symptoms and ultrasonographic findings of marked gallbladder dilatation or pericholecystic fluid collection.
Cholecystectomy
;
Cholecystectomy, Laparoscopic*
;
Cholecystitis, Acute
;
Cholecystostomy*
;
Dilatation
;
Drainage
;
Edema
;
Gallbladder
;
Gallstones
;
Humans
;
Inflammation
;
Postoperative Complications
;
Sex Distribution
;
Tissue Adhesions
10.Expression of Periostin and S100A2- S100A4-Calcium Binding Proteins mRNA in Human Gingival Fibroblasts and Periodontal Ligament Fibroblasts.
Byung Ock KIM ; Kyung Yoon HAN ; Young Sun CHOI ; Se Hoon KIM ; Byung Gi PARK ; Heung Joong KIM ; Joo Cheol PARK
The Journal of the Korean Academy of Periodontology 2001;31(1):109-121
Gingival fibroblasts(GF) and periodontal ligament fibroblasts(PDLF) are the major cellular components of periodontal soft connective tissues, but the precise molecular biological differences between these cells are not yet known. In the present study, we investigated the expression of S100A4, S100A2 calcium-binding protein and osteoblast-specific factor 2(OSF-2, Periostin) mRNA in GF and PDLF in vitro through the process of reverse transcription-polymerase chain reaction(RT-PCR) and Northern blot analysis in each. Human GF and PDLF were isolated from the gingival connective tissue and the middle third of freshly extracted healthy third molars. They were cultured in Dulbecco's Modified Eagle Medium(DMEM) containing 10% fetal bovine serum and cells in the third passage were used in the experiments. After extracting total RNA from cultured cells, RT-PCR and Northern analysis were performed using S100A4-, S100A2- and Periostin-specific oligonucleotide primers and subcloned cDNA probes in each. In RT-PCR and Northern analysis, the expression of S100A4 and Periostin mRNA in GF was slightly detectable. Interestingly, the expression of S100A4 and Periostin mRNA in PDLF was much higher than that in GF. On the other hand, S100A2 mRNA was highly expressed in both GF and PDLF. Since there was a marked difference of S100A4 and Periostin expression between GF and PDLF in vitro, these data suggest that S100A4 and Periostin could be used as a useful marker for distinguishing cultured gingival fibroblasts and periodontal ligament cells.
Blotting, Northern
;
Carrier Proteins*
;
Cells, Cultured
;
Connective Tissue
;
DNA Primers
;
DNA, Complementary
;
Eagles
;
Fibroblasts*
;
Hand
;
Humans*
;
Molar, Third
;
Periodontal Ligament*
;
RNA
;
RNA, Messenger*