1.Two cases of a family of benign familial hematuria.
Byung Sik CHANG ; Pyung Kil KIM ; Soon Hee SUNG
Korean Journal of Nephrology 1993;12(4):677-681
No abstract available.
Hematuria*
;
Humans
2.Fracture of the entire posterior process of the talus: A case report.
Byung Joon SHIN ; Hong Sik KIM ; Chang Uk CHOI
The Journal of the Korean Orthopaedic Association 1993;28(3):1177-1181
No abstract available.
Talus*
3.A case of agnogenic myeloid metaplasia.
Byung Jin KIM ; Byung Yeon KIM ; Jung Sik MIN ; Ho SEONG ; Chang Hee CHOI
Journal of the Korean Pediatric Society 1993;36(8):1178-1182
Agnogenic myeloid metaplasia (AMM) is a myeloproliferative disorder characterized by leukoerythroblastosis, tear-drop erythrocytes, extramedullary hematopoiesis with hepatosplenomegaly, and varying degrees of myelofibrosis. The mean age at presentation is about 60 years, and pediatric cases are rare. We experienced a case of AMM in a 9 months old female who was presented with pallor, huge splenomegaly and intermittent fever. Peripheral blood showed leukoerythroblastosis poikilocytosis, and tear drop cells. Bone marrow was difficult to aspirate, and biopsy specimen showed increased reticulin with decreased cellularity, which was compatible with myelofibrosis. We presented a case of AMM with brief review of the literatures.
Biopsy
;
Bone Marrow
;
Erythrocytes
;
Female
;
Fever
;
Hematopoiesis, Extramedullary
;
Humans
;
Infant
;
Myeloproliferative Disorders
;
Pallor
;
Primary Myelofibrosis*
;
Reticulin
;
Splenomegaly
4.The Significance of Monitoring Serum Carcinoembryonic Antigen in the Colorectal Cancer after Curative Resection.
Jin Cheon KIM ; Choon Sik JEONG ; Chang Nam KIM ; Sang Kyu PARK ; Chang Sik YU ; Byung Sik KIM ; Kun Choon PARK
Journal of the Korean Society of Coloproctology 1998;14(3):385-392
BACKGROUND/AIM: Serial measurement of serum carcinoembryonic antigen was assessed to define its significance and to determine the adequacy in detecting recurrence after curative resection for colorectal cancer. METHODS: Six hundred forty-five patients with colorectal cancer underwent curative resection were included. The median follow-up period was 49 months (range, 24~94 months). Serum CEA was analyzed in accordance with location, histologic differentiation, stage of the tumor, recurrence and survival. RESULTS: The incidence of elevated preoperative serum CEA (> 6 ng/ml) was correlated with tumor stage (stage I vs. II, P=0.01; stage II vs. III, P=0.0001). Fifty five patients among 87 patients with recurrence (63.2%) had concomitant elevation of serum CEA, whereas 32 of 558 patients (5.7%) without recurrence showed a false-positive result. Measurement of serum CEA was more sensitive in patients with elevated preoperative serum CEA and liver metastases than in patients without elevated preoperative serum CEA and local recurrence (P=0.0397). The leading time of serum CEA between the first elevated serum CEA and the identification of recurrence was 3.5 months (range, 1~12 month). Tumor stage and preoperative serum CEA level were found to be significant prognostic variables by multivariate analysis. The overall 5-year survival rate in the normal preoperative serum CEA and the elevated group were 76% and 64% respectively (P=0.00019). CONCLUSION: Serum CEA seemed to be closely correlated with survival and to be an useful tool to detect recurrence after curative resection for colorectal cancer. The appropriate measurement of serum CEA might be suggested in stage II and III postoperatively: every three month for two years, every 6 month for succeeding 2 years, and annually thereafter. Monitoring of serum CEA in stage I could be individualized by preoperative serum CEA and clinical course.
Carcinoembryonic Antigen*
;
Colorectal Neoplasms*
;
Follow-Up Studies
;
Humans
;
Incidence
;
Liver
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Recurrence
;
Survival Rate
5.A Case of Fordyce' s Disease Observed Demodex folliculorum.
Do Sik SONG ; Sun Wha LEE ; Kye Yong SONG ; Byung In RO ; Chin Yo CHANG
Korean Journal of Dermatology 1984;22(5):537-541
No abstract available.
6.Studies on the amplification and detection of bovine leukosis proviral DNA by PCR and ECL techniques.
Uh Ho KIM ; Chang Sik RA ; Soo Hwan AN ; Ji Byung YOON
Journal of the Korean Society of Virology 1992;22(1):1-12
No abstract available.
Animals
;
Cattle
;
DNA*
;
Enzootic Bovine Leukosis*
;
Polymerase Chain Reaction*
7.A case of idiopathic midline destructive disease a subgroup of midline granuloma syndrome.
Heung Sik CHANG ; Byung Dae KWUN ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1992;30(1):93-98
Idiopathic midline destructive disease(IMDD) is a subgroup of midline granuloma syndrome, which is a clinical entity characterized by a relentless uilcer ation of the upper air way involving the nose, the palate, and the face, with a fatal outcorne. A 32 year-old male had symptoms of nasal obstruct.ion and rhinorrhea for about 4 months prior to visiting the hospital ad was referred to our Department for evaluation of a verely destruct.ive skin lesions on his face. The patient, revealed unique clinopatholcgic featurs compat with IMDD. These were : 1) prescence of locally destructive lesion which were restricted to the upper respiratory tract. 2) abscence of systemic disease durin the follow up peroid, 3) The histologic features consisted of acute and chronic inflarnmation with a variable dearel of necrosis on the examination of repeated biopsy specimens, 4) inabiliy to demonst rate an infectious causative organisms on repeated laboratory tests.
Adult
;
Biopsy
;
Follow-Up Studies
;
Granuloma*
;
Humans
;
Male
;
Necrosis
;
Nose
;
Palate
;
Respiratory System
;
Skin
8.Traumatic rupture of thoracic aorta with pericardial rupture.
Hwan Kyu ROH ; Byung Chul CHANG ; Kye Jun LEE ; Nam Sik JUNG
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(10):1125-1131
No abstract available.
Aorta, Thoracic*
;
Rupture*
9.Nevus Lipomatosus Cutaneous superficialis (Hoffmann-Zurhelle): Report of Two Cases.
Dong Sik BANG ; Chang Jo KOH ; Sung Nack LEE ; Byung Moon CHOI ; Jung Bock LEE
Korean Journal of Dermatology 1981;19(3):359-363
Nevus lipomatosus cutaneous superficialis is a very rare skin disease which usually is present from birth. This uncommon condition is due to collections of ectopic. fat cells within the upper and mid dermis. There are two clinical varieties. The first is a lesion of zonal distribution, present from birth or childhood, usualIy on the buttocks or the lower back. The second form, a dome or sessile, papule, begins. in adult life and is less restricted in distribution. Cerebriform plaques tend to form from the coalescence of soft, yellowish papules. The authors observed two cases of typical nevus lipomatosus cutaneous superficialis. The first case is a 25-year-old female who has had asymptomatic, soft, skin colored, and huge confluent nodules on the right infragluteal fold and upper thigh for 15 years; and the second case is a 15-year-old male who has had multiple, skin colored and soft papules or nodules in zosteriform distribution affecting the right side of the lower back and coccygeal area and right buttock for 4 years. The authors made the diagnosis of nevus lipomatosus cutaneous superficialis from the characteristic clinical and histopathological findings.
Adipocytes
;
Adolescent
;
Adult
;
Buttocks
;
Dermis
;
Diagnosis
;
Female
;
Fluconazole
;
Humans
;
Male
;
Nevus*
;
Parturition
;
Skin
;
Skin Diseases
;
Thigh
10.Use of Tissue Adhesive for Prevention of Fibrotic Breakdown of Filtration Bleb.
Chang Sik KIM ; Byung Heon AHN
Journal of the Korean Ophthalmological Society 1989;30(2):267-275
In this experiment using 30 rabbits(40 normal eyes), the applicability of ocular adhesive, HISTOACRYL blue, as an implant beneath the scleral and conjunctival flap. Group 1 consisted of 10 left eyes. These eyes had undergone a fornix-based conjunctival flap and a triangular lamellar scleral flap without sclerectomy and served as a control on histologic examination. Group 2 consisted of 10 right eyes of the rabbits used in group 1. The Histoacryl was pasted on the sclera under the lamellar scleral flap and the conjunctiva. The pasted Histoacryl turned into a thin membrane. Group 3 consisted of 10 right eyes which had undergone a conventional trabeculectomy. Group 4 consisted of 10 right eyes. These eyes had undergone a trabeculectomy and placement of a Histoacryl membrane. The adhesive was applied closely to the limbus in 5 eyes and posteriorly away from the limbus in the remaining 5 eyes of group 4. At the eighth week after operation a filtering bleb was observed in all of the eyes in group In contrast to this, only two eyes showed filtering blebs in group 3. Filtering blebs were so confined over the Histoacryl membrane that their size and location was in accordance with the membrane. The vessels of the conjunctiva overlying the Histoacryl membrane were dilated and congested. This vascular congestion lasted long. The light microscopic examinations of the operation site showed a thick layer composed of macrophages, eosinophils, neutrophils, foreign body giant cells, and fibroblasts surrounding the Histoacryl membrane with cystic space between them. At the eight postoperative week, this wall remained thick measuring about 50-70 micro thick. From the result, Histoacryl appeared to be effective in preventing the fibrotic scarring down of the filtering bleb, but postoperative inflammatory changes indicated that the Histoacryl seemed to be rather unsuitable for clinical application.
Adhesives
;
Blister*
;
Cicatrix
;
Conjunctiva
;
Enbucrilate
;
Eosinophils
;
Estrogens, Conjugated (USP)
;
Fibroblasts
;
Filtration*
;
Giant Cells, Foreign-Body
;
Macrophages
;
Membranes
;
Neutrophils
;
Rabbits
;
Sclera
;
Tissue Adhesives*
;
Trabeculectomy