No abstract available.
Cervix Uteri* ; Female ; Magnetic Resonance Imaging*

A case, 25-year-old male student who is thought to have been suffered from glaucomatocyclitic crises in the left eye, is presented. Authors have followed this patient for about one and a half years. During the time, 10 times of recurrent unilateral attacks of ocular hypertension have been noted with assoicated mild iridocyclitis. An attempt was made to evaluate the clinical pictures and review the literatures.
Adult ; Humans ; Iridocyclitis ; Male ; Ocular Hypertension

In order to investigate the effects of diathermy and cryosurgery on the scleral shrinkage, nonperforating surface diathermy and cryocautery were applied in rabbits eyes. The premarked scleral segments were measured by corneal microscope with micrometer, and the resultant elevation of the intraocular pressures was pressures was measured by Schiotz tonometer. In the eyes treated by 10 diathermy in 5 X 3mm area, average 20.1% of scleral shrinkage was observed. There was no significant difference between shrinkages in the meridional and latitudinal directions. In the eyes treated by cryopencil no significant changes were found. Diathermy applications in 3 X 10mm area in the sclera induced 36.9% increase in the intraocular pressure which lasted about 9 minutes. On the other hand, cryoapplication did not produce such an elevation in ocular tension.
Cryosurgery ; Diathermy* ; Hand ; Intraocular Pressure ; Rabbits* ; Sclera

The authors presented a case of malignant melanoma of the choroid which had been unsuspected clinically. The patient, 38-year-old female, came to Korea General Hospital on Dec. 5-1973 because of blind painful eye and white pupil in the left side. And she was told at local clinic that she had retinal detachment in that eye about 3 years ago. We thought of this case as secondary glaucoma due to swollen lens behind at first. Therefore cryoextraction of the lens was performed for relieving the ocular pain, on Dec. 5-1973. Increased I.O.P., however, had been persisted and ocular pain had not been improved until the patient entered this hospital again on Jan. 25-1974. Enucleation was performed and choroidal malignant melanoma (spindle type) was proven by histopathological study. The patient was instructive to us that we should always remind the possibilities of intraocular tumor behind the opaque media, in cases of unilateral glaucomatous blind eye with shallow anterior chamber.
Adult ; Anterior Chamber ; Choroid* ; Female ; Glaucoma ; Hospitals, General ; Humans ; Korea ; Melanoma* ; Pupil ; Retinal Detachment

After the immunization of pigmented guinea pigs with bovine rod outer segments in complete Freund's adjuvant, the regional lymph nodes were excised, teased and sedimented by centrifugation. These fresh lymphocytes were injected intravitreally (a single injection of 10 X 10 cells in 50 micro l) in 18 eyes. The involvement of the ciliary body and the choroid with polymorphonuclear leucoytes and later with round cells was noted in 16 eyes. Destructions of the visual cells of the retina were demonstrated in 8 eyes. When the fresh lymphocytes were injected subconjunctivally (50 X 10 cells in 30 micro l) four times. four of the 8 eyes showed slight infiltrations of the ciliary body and the choroid with round cells. No retinal lesion was found. Following repeated freezing and thawing of the lymphocytes. transfer experiments wereperformed with the nonviable cells and their extracts respectively. In 8 eyes injected intravitreally with nonviable cells. 2 eyes showed the infiltration of the uvea with round cells, whereas. of 6 eyes injected subconjunctivally, only one eye showed such changes. The extracts of lymphocytes were injected intravitreally in 8 eyes of which 5 eyes demon-strated moderate degree of infiltration of the uvea. Of 2 eyes injected subconjunctivally, 2 eyes. showed slight histological changes. As control experiments, lymphocytes taken from animals immunized. only with the adjuvant were treated as before and transferred to normal animals. Only one eye of 3 eyes received single intravitreal injection of fresh cells showed slight degree of infiltration of the uvea. Thus it can be concluded that the experimental autoimmune uveitis in guinea pigs could be transferred to normal animals by the transfer of non-viable lymphocytes and especially by their extracts.
Animals ; Centrifugation ; Choroid ; Ciliary Body ; Freezing ; Freund's Adjuvant ; Guinea Pigs ; Immunization ; Intravitreal Injections ; Lymph Nodes ; Lymphocytes ; Retina ; Retinaldehyde ; Rod Cell Outer Segment ; Uvea ; Uveitis*

BACKGROUND: C-fos is a marker of neuronal activity and its expression may be related to various types of stimulation of primary sensory neurons. We evaluated the effect of superior cervical ganglionectomy on c-fos expression in rat brain, which was expected to have the same effect as stellate ganglion block in human. METHODS: Male Sprague-Dawley rats (140-150 g) were divided into 4 groups; a no treatment (control group, n = 10), a 2 hour enflurane inhalation (anesthesia group, n = 10), a cervical skin incision only group (sham group, n = 10) and a superior cervical ganglionectomy group (sympathectomy group, n = 10). Two hours after each procedure, rats were killed and perfused with formaldehyde solution. c-fos protein expressions in the thalamus, hypothalamus, cortex, amygdala and cingulate gyrus were examined by immunohistochemistry using a specific antibody. RESULTS: In the thalamus, c-fos expression increased in the sympathectomy group vs. the control and the anesthesia groups, and in the sham group vs. the control group. In amygdala, the sham group showed significantly higher c-fos expression than the control group. In the hypothalamus and cortex no significant differences among the 4 groups were apparent. In the cingulate gyrus higher c-fos expression was observed than the control and anesthesia group but no differences with sham group. CONCLUSIONS: Superior cervical ganglionectomy itself may not affect c-fos expression in rat brain. For best results special effort should be made to avoid surgical or emotional stress.
Amygdala ; Anesthesia ; Animals ; Brain* ; Enflurane ; Formaldehyde ; Ganglionectomy* ; Gyrus Cinguli ; Humans ; Hypothalamus ; Immunohistochemistry ; Inhalation ; Male ; Neurons ; Rats* ; Rats, Sprague-Dawley ; Sensory Receptor Cells ; Skin ; Stellate Ganglion ; Stress, Psychological ; Sympathectomy ; Thalamus

A 66-year-old man visited author's institute complaining of the swelling on the submandibular gland area. Clinically, the exophytic mass penetrated the skin of the submandibular area. On MRI, the lesion occupied the left submandibular space and extended downward, protruding exterior to the subcutaneous fat layer, but the center of the lesion was located on the side of the skin and the growth exterior to the skin was prominent. Demarcation of the lesion and the submandibular gland was unclear. Histopathologically the epithelial nests and keratin production were seen, then the biopsy result was squamous cell carcinoma. The stroma of lesion showed a myxoid characteristic and some ducts showed metaplasia of the ductal cells, which suggested the gland-origin carcinoma. However, lots of keratin production and carcinomatous change of cells continuous to the normal epithelium of the skin, the skin-origin carcinoma invading into the submandibular gland area could not be excluded.
Aged ; Biopsy ; Carcinoma, Squamous Cell* ; Epithelium ; Humans ; Magnetic Resonance Imaging ; Metaplasia ; Skin ; Subcutaneous Fat ; Submandibular Gland

A 66-year-old man visited author's institute complaining of the swelling on the submandibular gland area. Clinically, the exophytic mass penetrated the skin of the submandibular area. On MRI, the lesion occupied the left submandibular space and extended downward, protruding exterior to the subcutaneous fat layer, but the center of the lesion was located on the side of the skin and the growth exterior to the skin was prominent. Demarcation of the lesion and the submandibular gland was unclear. Histopathologically the epithelial nests and keratin production were seen, then the biopsy result was squamous cell carcinoma. The stroma of lesion showed a myxoid characteristic and some ducts showed metaplasia of the ductal cells, which suggested the gland-origin carcinoma. However, lots of keratin production and carcinomatous change of cells continuous to the normal epithelium of the skin, the skin-origin carcinoma invading into the submandibular gland area could not be excluded.
Aged ; Biopsy ; Carcinoma, Squamous Cell* ; Epithelium ; Humans ; Magnetic Resonance Imaging ; Metaplasia ; Skin ; Subcutaneous Fat ; Submandibular Gland

BACKGROUND: The timing of tracheal extubation in patients undergoing major intraoperative procedures is controversial. Immediate postoperative tracheal extubation after liver transplantation was not popularized. But in these days, early tracheal extubation has been safely performed in certain cases and routine use of mechanical ventilation is being questioned. We performed preliminary study of our 25 liver transplantation cases to evaluate factors affecting duration and indications of postoperative mechanical ventilation. METHODS: Our 25 cases were divided into two groups by periodic difference - early 13 cases (group 1) and late 12 cases (group 2). We evaluated preoperative UNOS (united network for organ sharing) scale, intraoperative transfusion and vasopressor requirement, postoperative multiple organ complications which would have influence upon tracheal extubation. RESULTS: We found great difference between two groups in duration of mechanical ventilation (Group 1: 94.4+/-7.12 hrs, Group 2: 36.1+/-28.3 hrs) and ICU stay (Group 1: 22.8+/-8.3 days, Group 2: 11.8+/-5.5 days). CONCLUSIONS: We concluded that early tracheal extubation in selected liver transplantation cases was safe and effective because it could shorten duration of ICU stay and reduce postoperative mortality. But more experience and knowledge may be needed to get more ideal guidelines for postoperative mechanical ventilation.
Airway Extubation* ; Humans ; Liver Transplantation* ; Liver* ; Mortality ; Respiration, Artificial

Both a laryngeal web and thyroid cartilage anomaly are rare airway abnormalities and can cause the obliteration of the tracheal diameter, which may be asymptomatic or symptomatic. In asymptomatic patients, the presence of unsuspected obliteration of the tracheal diameter may be problematic if endotracheal intubation is indicated. We report a case of unsuspected difficult intubation caused by a combined laryngeal web and congenital anomaly of the thyroid cartilage. A 14-year-old female was scheduled for corrective surgery for idiopathic scoliosis of the spine. After injection of IV induction agent and muscle relaxant, most of the vocal cords were exposed clearly by laryngoscopy, but a 6.0 mm internal diameter (ID) endotracheal tube could not be advanced below the level of the vocal cords because of resistance. Intubation was re-attempted with smaller tube (5.0 mm ID) only to fail. We awakened the patient and consulted an otolaryngologist. An Otolaryngologic examination and radiologic study revealed the narrowing of the trachea was caused by a laryngeal web and congenital anomaly of the thyroid cartilage. Later, a tracheotomy was performed under local anesthesia and then the laryngeal web and anomalous portion of the thyroid cartilage were removed under general anesthesia.
Adolescent ; Anesthesia, General ; Anesthesia, Local ; Female ; Humans ; Intubation* ; Intubation, Intratracheal ; Laryngoscopy ; Laryngostenosis* ; Scoliosis ; Spine ; Thyroid Cartilage* ; Thyroid Gland* ; Trachea ; Tracheotomy ; Vocal Cords