Partial lipoatrophy is a relatively rare disease characterized by depression in certain areas of body due to absence of subcutaneous fat tissue. In the typical case, the face is affected first, and gradually spreads to the upper half of the body. Recently, Imamura et al reported an atypical form of partial lipoatrophy characterized by involvement of abdomen and neighboring regions and centrifugal enlargement of the lesions with re4dish and scaly change in the surrounding area. They proposed. the name lipodystrophia centrifugalis a,bdominalis infantilis for this disorder. The authors reported two cases of partial lipoatrophy sirnilar to the cases of Imamura et al. Case 1 was 5 year-old female with depressed Iesions on the lower abdomen, inguinal areas, and around the external genital and perineal areas. Eliopsy specimen showed absence of subcutaneous fat tissue. Case 2 was 5 year-old. female with depressed lesions on the left lower abdomen and inguinal region Riopsy specimen showed decrease in subcutaneous fat and inflammatory infiltrates in the dermis and subcutis.
Abdomen ; Child, Preschool ; Depression ; Dermis ; Female ; Humans ; Rare Diseases ; Subcutaneous Fat

Numerous cicatrizing and granulomatous diseases that simultaneously involve choroid, retina and their intervening Bruch's membrane may cause choroidoretinal vascular anastomoses. Anastomoses at capillary level and in neovascular granulomatous tissue are probably not uncommon under these and related circumstances, but choroidal connections to large-caliber segments of otherwise normal retinal arterioles and venules are unusual. We retrospectively studied 44 eyes of 44 patients with choroidal ruptures after blunt trauma. Of 44 choroidal ruptures, three patients had chorioretinal ruptures and choroidoretinal vascular anastomoses. This report describes three cases of large-caliber choroidoretinal anastomoses after chorioretinal ruptures.

The pilomatricoma (Calcifying Epithelioma of Malherbe) is rare benign tumor of adnexal keratinocytes. It is occuring usually as a single, asymptomatic, 0. 5 cm to 3. 0 cm sized, deep seated, firm nodule, covered by normal or pink skin. Multiple pilomatricoma is relatively rare, as 3. 5% of reported cases of pilomatricoma. A 21-year-old male patient had 7 subcutaneous nodules on the neck, both upper extremities and trunk for 9 years. We excised one of them, under the impression of calcinosis cutis, cysticercosis cutis or benign skin tumor. But histopathologic findings of the lesion showed the typical pattern of pilomatricoma with shadow cells, calcification and foreign body giant cells. Five of remainders were excised and they showed same histopathological findings of pilomatricoma. The authors presented herein one case of multiple pilomatricoma with the review of literature.
Calcinosis ; Carcinoma ; Cysticercosis ; Giant Cells, Foreign-Body ; Humans ; Keratinocytes ; Male ; Neck ; Pilomatrixoma* ; Skin ; Upper Extremity ; Young Adult

Two cases of hyperlipoproteinemia is reported, Hyperlipoproteinemia is characterized by various kinds of cutaneous xanthomatosis associated with or without arteriosclerotic changes due to increasing lipoprotein fraction of the serum. Case I . 37-year old housewife had multiple, pea to nut sized, various shaped, cutaneous and subcutaneous nodular masses has been developed last 3 years. Some of her family member have similar symptoms. Serum cholesterol level was 790 mg% and serum triglyceride level was 270 mg% after 14 hour fasting. Case II. 52-year old housewife was suffered from pea sized, multiple, subcutaneous nodular and cutaneous eruptions last 2 years. There was no family histories. Serum cholesterol level was 895 mg% and serum triglyceride level was 350 mg% after 14 hour fasting. Typical Touton giant cells were found in biopsy specimens taken from cutaneous lesons. ECG, X-ray, glucose toleranc test and other laboratory examinations showed within normal limits. Tne agarose electrophoresis pattern of serum lipoprotein fractions are very similiar with that of hyperlipoproteinemia type II. These two patients were treated with nicotinic and 1. 0 gm and clofibrate 2.0 gm daily by mouth and restricted animal fatty foods. Total serum cholesterol level was markedly decreasea 2 months after treatment in case I.
Adult ; Animals ; Biopsy ; Cholesterol ; Clofibrate ; Electrocardiography ; Electrophoresis ; Fasting ; Giant Cells ; Glucose ; Humans ; Hyperlipoproteinemia Type II ; Hyperlipoproteinemias ; Lipoproteins ; Middle Aged ; Mouth ; Nuts ; Peas ; Sepharose ; Triglycerides ; Xanthomatosis

No abstract available.
Child* ; Dinitrochlorobenzene* ; Humans ; Immunotherapy* ; Warts*

This study was performed in order to explore the immunologic relationship between the skin lesions induced by the human serum and the lymphatic organs. For these purposes, the authors induced the dermatitis in the rabbits by the injections of pooled human serum with Freunds complete adjuvant into the skin, and administered prednisolone and azathioprine as immunosuppressive drugs to the rabbits. Immunologic asmy was performed by the measurement of the plasma ceIls and immunogobulin-bearing B lymphocytes in lymph node and spleen. The results were as follows: 1. By the injections of human serum pyroninophilic cells and immunoglobulining B lymphocytes in lymph node and spleen were increased. 2. By the administrations of prednisolone and azathioprine, pyroninophilic cells and immunoglobulin-bearing B lymphocytes in lymph node and spleen were all decre RSCd.
Azathioprine ; B-Lymphocytes ; Dermatitis* ; Humans ; Immunoglobulins ; Lymph Nodes ; Plasma ; Prednisolone ; Rabbits* ; Skin ; Spleen

Trichotillomania is the cllinical syndrome of alopecia resulting from the repetative pulling, plueking and breaking of ones own hair. We report four cases of trichotillomania in 10 year old children. The lesions were limited to the scalp. All of them had psychiatric problems in the school or home according to a psychiatric consultation. The histopathologic examinatiorii revealed a normal number of hair follices, empty hair follicles and no inflammatory reaction. The treatment led to hair growth in three cases but one case did not respond to the treatment.
Alopecia ; Child ; Hair ; Hair Follicle ; Humans ; Scalp ; Trichotillomania*

A 6-year-old male patient had been suffering from angular cheilitis and paronychia with fragmentation and dystrophic change of the finger nails. Laboratory findings showed low serum iron level and anemia. Immunologic studies revealed defects in cell mediated immunity. KOH examination and culture of specimens from the lesions showed hyphal elements and growth of Candida albicans respectively. Concomitantly itraconazole and iron sulfate were administered. Four months after treatment he was free of any clinical evidence of the disease.
Anemia ; Candida albicans ; Candidiasis, Chronic Mucocutaneous* ; Cheilitis ; Child ; Fingers ; Humans ; Immunity, Cellular ; Iron ; Itraconazole ; Male ; Paronychia

Tinea barbae is one of the relatively rare chronic dermatophytosis of adult male, developing on the beard and moustache area of the face. We observed in a 50-year-old male patient who showed atypical clinical findings of tinea barbae. Initially, we impressed sycosis vulgaris, due to diffuse multiple pustular nodules with swelling on the beard area and both cheek of the face. We had treated him by antibiotics anri no improvement was noticed. On the 20th day from first visit, Trichophyton mentagrophytes was identified, and histopathologic exam revealed many spores and hyphae on the hair follicle. His skin lesions were almostly cleared after injestion of 5 months period of griseofulvin.
Adult ; Anti-Bacterial Agents ; Cheek ; Folliculitis ; Griseofulvin ; Hair Follicle ; Humans ; Hyphae ; Male ; Middle Aged ; Skin ; Spores ; Tinea* ; Trichophyton

A case of a 21-year old female with Maffucci's syndrome is presented where the patient developed multiple cutaneous spindle-cell hemangioendotheliomas. She had multiple pea to walnut sized, non-tender, normal skin colored or slight bluish nodules and bony mass-like lesions on the left upper extremity and hand. A histological examination of the lesions showed that they were composed of irregularly dilated, thin walled cavernous blood spaces containing phleboliths and collapsed vascular spaces separated by spindled fibroblastic cells. Radiologically, the bony lesions showed radiolucent densities with calcified spots within the second proximal phalanx and metacarpal bone of the left hand, which were consistent with enchondromas.
Chondroma ; Female ; Fibroblasts ; Hand ; Hemangioendothelioma* ; Humans ; Juglans ; Peas ; Skin Pigmentation ; Upper Extremity