1.Leiomyosarcoma of the left external iliac vein
Byung Jun SO ; Kwon Mook CHAE ; Byung Suk ROH ; Hyung Bae MOON
Journal of the Korean Society for Vascular Surgery 1992;8(1):96-102
No abstract available.
Iliac Vein
;
Leiomyosarcoma
2.Effect of Taxol on the Function of Murine Microglial Cells.
Byung Moon CHAE ; Jong Moon KIM
Journal of Korean Neurosurgical Society 1996;25(3):519-525
The effect of taxol on the production of nitric oxide(NO) and reactive oxygen radicals(O2- and H2O2)and on the function of phagocytic activity of murine microglial cells were investigated. Stimulated cells also showed increased production such reactive oxygen radicals as surperoxide and hydrogen peroxide measured by luminometer after stimulated with phorbolmyristate acetate(PMA). Taxol alone had only being small effect on NO synthesis, whereas taxol in combination with rIFN-gamma synergistically increased NO synthesis in a dose dependent manner. The production of NO by taxol plus rIFN-gamma was reduced by such L-arginine analogues as N(G)-mono-metyl-L-arginine Monohydrate(N(G)MMA), and N-amino-L-arginine(NAA) and arginase which decomposes L-arginine. Collectively, the data illustrate the potential for taxol to activate microglia-mediated anticancer mechanisms in the brain in addition to its better characterized effects on ovarian, beast, and lung cancer.
Arginase
;
Arginine
;
Brain
;
Hydrogen Peroxide
;
Lung Neoplasms
;
Oxygen
;
Paclitaxel*
;
Reactive Oxygen Species
3.Comparison of Clinical Outcomes according to the Catheters undergoing Intrauterine Insemination.
Hee Dong CHAE ; Eun Hee KANG ; Chung Hoon KIM ; Byung Moon KANG ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 2000;43(2):254-259
OBJECTIVE: To compare the clinical outcomes of intrauterine insemination (IUI) according to the catheter used. MATERIALS AND METHOD: From March 1998 to September 1998, total 95 infertile patients were included in this study. Patients were randomly allocated to TomCat group (n = 39) and Mackler group (n = 56) according to the catheter for insemination. The controlled ovarian hyperstimulation (COH) using luteal long protocol of gonadotropin releasing hormone agonist (GnRH-a) was used in all patients. Statistical analysis was performed using Student's t-test, Fisher's exact test, and x2 test as appropriate. Statistical significance was defined as p < 0.05. RESULTS: The total dose and duration of exogeneous gonadotropin required were similar between the two groups. There were also no significant differences in serum estradiol (E2) level, endometrial thickness and texture on the day of hCG administration between the two groups. However, the percentage of uterine souding due to failure of initial approach was significantly higher in TomCat group compared to Mackler group (23.1% vs. 0%, p < 0.01). The percentage of bleeding after IUI in TomCat group seemed to be higher than that in Mackler group (15.4% vs. 3.6%, p = 0.06), although there was no statistically significant difference between the two groups. There was also no significant difference in the clinical pregnancy rate per patient between the two groups. CONCLUSION: These results suggested that using Mackler catheter might be effective for IUI, especially for the patients with cervical factor infertility.
Catheters*
;
Estradiol
;
Gonadotropin-Releasing Hormone
;
Gonadotropins
;
Hemorrhage
;
Humans
;
Infertility
;
Insemination*
;
Pregnancy Rate
4.A case of Mullerian adenocarcinoma of ovary.
Sook CHO ; Byung Moon KANG ; Gu Sang KIM ; Young Chae CHU
Korean Journal of Obstetrics and Gynecology 1992;35(4):608-612
No abstract available.
Adenocarcinoma*
;
Female
;
Ovary*
5.Clinical Usefulness of Intracytoplasmic Sperm Injection of 1-day-old Unfertilized Oocyte during IVF-ET.
Chung Hoon KIM ; Hyung Sik CHU ; Eun Hee KANG ; Hee Dong CHAE ; Byung Moon KANG ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1999;42(11):2440-2445
OBJECTIVE: To analyze the efficacy of intracytoplasmic sperm injection (ICSI) for totally unfertilized oocytes by the conventional insemination during in vitro fertilization and embryo transfer (IVF-ET) METHODS: From March 1996 to April 1998, 15 couples who experienced total fertilization failure after conventional IVF without severe male factor infertility in semen analysis were evaluated. Fertilization were assessed by the presence of 2 pronucleus (PN) after 14-16 hours of conventional insemination. All unfertilized oocytes were reinseminated by ICSI and checked for signs of fertilization between 6-10 hours after ICSI. The embryos with fertilization and development were transferred to the uterine cavity and the outcome was analyzed. RESULTS: Total numbers of unfertilized oocytes were 120, and total numbers of oocytes injected on day 1 using ICSI were 102. Total numbers of oocytes with normal fertilization after ICSI were 74 and mean fertilization rate of 71.1 +/- 24.0% was obtained. The numbers of embryos transferred was 3.6 +/- 1.7. The biochemical pregnancy rate was 13.3% (2/15) and the clinical pregnancy rate was 6.7% (1/15) per cycle. CONCLUSION: ICSI to totally unfertilized oocytes by conventional insemination technique during IVF-ET on the next day of oocyte retrieval seems to be a relatively successful mean and afford a chance of pregnancy to the infertile couples whom the ET could not perfomed to because of total fertilization failure."
Embryo Transfer
;
Embryonic Structures
;
Family Characteristics
;
Fertilization
;
Fertilization in Vitro
;
Humans
;
Infertility
;
Insemination
;
Male
;
Oocyte Retrieval
;
Oocytes*
;
Pregnancy
;
Pregnancy Rate
;
Semen Analysis
;
Sperm Injections, Intracytoplasmic*
6.Prognostic Factors of Ovarian Response to Clomiphene Citrate in Patients with Polycystic Ovarian Syndrome.
Dae Jin KIM ; Hee Dong CHAE ; Cherl SOHN ; Chung Hoon KIM ; Byung Moon KANG ; Yoon Seok CHANG ; Jung Eun MOK
Korean Journal of Fertility and Sterility 1998;25(2):141-151
OBJECTIVES: To determine whether the body weight, body mass index (BMI), and basal serum level of LH, FSH, testosterone (T), dehydroepiandrosterone sulfate (DHEA-S) are related to the ovarian response to clomiphene citrate (CC) in patients with polycystic ovarian syndrome (PCOS). MATERIALS AND METHOD: From January 1996 to June 1997, total 57 patients with PCOS were enrolled in the present study. Women who had other infertility factors were excluded from our study. The ovulation induction using CC was used in all patients. The patients were grouped into 50 mg group, 100 mg group, and 150 mg group according to their daily CC dose. The patients were also grouped to ovulatory and non-ovulatory group. The body weight, BMI, arid basal serum level of LH, FSH, T, DHEA-S were measured in all patients on the 2nd or 3rd day of the menstrual cycle. Results were analysed with Student's t-test and Fisher's exact test. RESULTS: The body weight and BMI of the nonovulating group were significantly higher than those of the ovulating group in all groups (50, 100, 150 mg of CC). However, there were no significant differences of the level of LH and FSH between ovulating and nonovulating groups in all CC groups (50, 100, 150 mg). The level of T of nonovulating group was significantly higher in 50 and 100 mg of CC groups, but not in 150 mg group. The level of DHEA-S of the non-ovulating group is significantly higher in 50 mg group, but not in 100 and 150 mg groups. CONCLUSION: The body weight and BMI could be useful predictors of ovarian response to CC in patients with PCOS, and basal T and DHEA-S also might be useful in cases of low-dose CC treatment.
Body Mass Index
;
Body Weight
;
Clomiphene*
;
Dehydroepiandrosterone Sulfate
;
Female
;
Humans
;
Infertility
;
Menstrual Cycle
;
Ovulation Induction
;
Polycystic Ovary Syndrome*
;
Testosterone
7.Anesthesia for Transurethral Resection in 97 Cases .
Sang Ho LIM ; Byung Kuk CHAE ; Sook Hee MOON ; Jung Soon SHIN
Korean Journal of Anesthesiology 1979;12(3):238-242
Consecutive anesthesia records of transurethral resection. (TUR) on 97 patients have been reviewed. The patients' anesthetic management and complications were discussed. Operations in this series were classified as follows: 65 cases of TUR of the benign prostate hypertrophy(BPH), 8 cases of TUR of prostate ca, 24 cases of TUR of the bladder tumor. Of all the 97 cases of TUR, 62 cases had some systemic disease. Circulatory diseases, such as hypertension, abnormal EKG and ischemic heart disease were encountered most frequently, namely in 24 cases(26%). The patients who underwent TUR of the BPH had the highest mean age(70 years old). Spinal anesthesia was given 79.4%, and general anesthesia in 18. 6%. Complications did not occur during or after TUR. There was no death associated with anesthesia and operation in this study.
Anesthesia*
;
Anesthesia, General
;
Anesthesia, Spinal
;
Electrocardiography
;
Humans
;
Hypertension
;
Myocardial Ischemia
;
Prostate
;
Urinary Bladder Neoplasms
8.A Case of Extensive Female Urethral Loss Treated Using Bulbocavernous Myocutaneous Flap.
In Yong CHAE ; Moon Hwan CHO ; Kap Byung KIM ; Hyun Yul RHEW
Korean Journal of Urology 1989;30(6):965-968
Loss of the urethral floor with total urinary incontinence is a difficult problem that is infrequently encountered by the urologist. The techniques required for the urethral reconstruction are different and can be much more; delicate and demanding than the typical vesicovaginal fistula repair. Herein we report a case of the female urethral loss caused by chemical injury 3 years age and treated using bulbocavernous myocutaneous flap successfully.
Female*
;
Humans
;
Myocutaneous Flap*
;
Urinary Incontinence
;
Vesicovaginal Fistula
9.A Case of Combined Ectopic Gestation with Cervical and Tubal Components.
Seung Hwa HONG ; Hye Eun KWON ; Sung Hoon KIM ; Hee Dong CHAE ; Chung Hoon KIM ; Byung Moon KANG
Korean Journal of Fertility and Sterility 2003;30(3):249-254
Ectopic pregnancy is a common medical problem that is difficult to diagnose and potentially may lead to significant mortality or morbidity. The incidence of ectopic pregnancy is definitely increasing due to the rise in pelvic inflammatory disease (PID), pelvic surgery, intrauterine device (IUD), and assisted reproductive technologies, such as in vitro fertilization and embryo transfer (IVF-ET). Combined ectopic gestations are much rare and their true incidence is unknown. Multiple ectopic gestations may occur in a variety of locations. The majority involve one or both fallopian tubes. We report a case of combined tubal and cervical pregnancies, and discuss their management.
Embryo Transfer
;
Fallopian Tubes
;
Female
;
Fertilization in Vitro
;
Incidence
;
Intrauterine Devices
;
Mortality
;
Pelvic Inflammatory Disease
;
Pregnancy*
;
Pregnancy, Ectopic
;
Reproductive Techniques, Assisted
10.Basal Serum Luteinizing Hormone Levels as a Prognostic Indicator of Ovarian Response to Controlled Ovarian Hyperstimulation.
Chung Hoon KIM ; Hee Dong CHAE ; Byung Moon KANG ; Yoon Seok CHANG ; Eun Hee KANG ; Mi Duk SEO ; Cheon HWANGBO
Korean Journal of Obstetrics and Gynecology 1999;42(8):1706-1712
OBJECTIVE: To evaluate whether the basal serum luteinizing hormone (LH) levels in the presence of normal serum follicle stimulating hormone (FSH) are useful as a prognostic indicator of ovarian response to controlled ovarian hyperstimulation (COH). METHODS: From January 1997 to January 1999, 91 infertile women with tubal factor who had undergone in vitro fertilization and embryo transfer (IVF-ET) were enrolled in the present study. COH was performed using long protocol of gonadotropin-releasing hormone (GnRH) agonist. All patients included in this study had blood samples drawn on cycle day 2 or 3 prior to COH for measurement of basal FSH and LH. Women who had other infertility factors or high basal FSH levels (> or = 8.5 mIU/ml) were excluded from this study. The results of COH and IVF-ET were compared between two groups according to the level of basal LH (low LH group [< 3mIU/ml] vs. control group [> or = 3mIU/ml]). RESULTS: Patient's characteristics were comparable in both groups except basal LH level. The number of ampules and duration of exogenous gonadotropins required were significantly higher in the low LH group than those in the control group (p<0.001; p<0.005, respectively). The number of follicles > or = 14mm diameter on the day of human chorionic gonadotropin (hCG) injection was significantly less in the low LH group than that in the control group (p<0.001). The serum estradiol level on the day of hCG injection was also significantly lower in the low LH group, with 1115.5 +/- 380.9 pg/ml compared with 1340.6 +/- 403.0 pg/ml in the control group (p<0.005). There were significantly lower numbers in oocytes retrieved, oocytes fertilized and embryos frozen in the low LH group than those in the control group (< 0.001; < 0.001; <0.005, respectively). However, there was no difference in the fertilization rate between the two groups. The clinical pregnancy rate per cycle seemed to be lower in the low LH group, but the difference did not achieve significance (26.2% vs 39.7%). There were no differences in the miscarriage rate and multiple pregnancy rate between the two groups. CONCLUSION: This study demonstrates that the low basal LH levels ( < 3 mIU/ml) could be predictive of low ovarian response to COH and poor IVF results.
Abortion, Spontaneous
;
Chorionic Gonadotropin
;
Embryo Transfer
;
Embryonic Structures
;
Estradiol
;
Female
;
Fertilization
;
Fertilization in Vitro
;
Follicle Stimulating Hormone
;
Gonadotropin-Releasing Hormone
;
Gonadotropins
;
Humans
;
Infertility
;
Lutein*
;
Luteinizing Hormone*
;
Oocytes
;
Pregnancy
;
Pregnancy Rate
;
Pregnancy, Multiple