To determine the concentration and the physiologic role of metal components in blood plasma and seminal plasma in relation to male infertility, the concentrations of twelve metal components in blood plasma and seminal plasma including Na, Mg, K, Ca, Cr, Mn, Fe, Cu, Zn, Se, Cd and Pb were measured by atomic absorbance spectrophotometery or ion selective electrode analysis. Semen and blood samples were obtained from a total of 110 men including 70 male infertility patients, 20 vasectomized persons and 20 fertility proven volunteers visited to the Male Infertility Clinic of Pusan National University Hospital. The concentrations of Ca, Zn, Mg, Cr and Cd in control group were higher in seminal plasma than in blood plasma, and additionally Pb were higher in infertility group. The concentrations of all metal components revealed no significant difference according to patients' age, resident, occupation, sperm density, motility and hormone level in blood plasma, but some metal components including Ca, Mg, Cu, Mn, Cd and Pb revealed a significant difference according to each these parameters except patient's age in seminal plasma. The concentrations of Mn, Cd and Pb in the vasectomy persons were higher than in the infertility group III including testicular and epididymal factors, but not in blood plasma. We conclude that the quantitative changes of metal components in the seminal plasma may have effects on not only spermatogenesis and sperm function, but also contribute to diagnostic parameter according to organ specificity of the metal in the male reproduction.
Busan ; Electrodes ; Fertility ; Humans ; Infertility ; Infertility, Male ; Male* ; Occupations ; Organ Specificity ; Plasma ; Reproduction ; Semen* ; Spermatogenesis ; Spermatozoa ; Vasectomy ; Volunteers

In these days, there are two main ways in the treatment of the avascular necrosis of the femoral head in adult by prosthetic replscement; total hip replacement and bipolar endoprosthesis. So far, no study has been performed on the post-operative functional evaluation of them. Therefore it is difficult to decide which one is preferred to the other in the treatment of avascular necrosis of the femoral head in adult. In order to evaluate the functions of the prosthetic joints, the authors reviewed the results of 18 cases of cementless bipolar endoprosthesis(abbreviated as CBE) and 22 csses of cementless total hip replscement arthroplasty(abbreviated as CTHRA), performed at the Department of Orthopedic Surgery, Seoul National University Hospital, during the period from February, 1984 to May, 1986. The following results were obtained. 1. The average ages of CBE and CTHRA groups at the time of operation were 48.5 years and 37.5 years, respectively. 2. The average follow-ups of CBE and CTHRA were 15.7 months and 30.5 months, respectively. 3. By Meyer's modification of Marcus and Enneking classification, the sverage stages of CBE and CTHRA groups were 3.7 and 4.4 respectively. 4. According to Harris hip rating score system, Harris scores were increased as much as 30.5 in CBE group and 30.6 in CTHRA group. 5. In the aspects of functional improvement and relief of pain, the two groups showed no significant difference. However, the operation was essier, and the damage to the acetabular bone was less in CBE group. For these reasons, CBE was believed to be the preferred choice of treatment of avascular necrosis of femoral head in adult.
Acetabulum ; Adult ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Classification ; Follow-Up Studies ; Head ; Hip ; Humans ; Joints ; Necrosis ; Orthopedics ; Seoul

No abstract available.
Antibodies, Neutralizing* ; Feces* ; Rotavirus*

This study was carried out to investigate the localization and change of the cell surface antigens, such as URO-9(Om5) and URO-10 (T43), in transitional cell carcinomas of bladder. The subjects used were normal bladder mucosae of 10 autopsy cases of fetus and 10 biopsy cases of child or adult patients with disease of other organs as controls, and neoplastic tissue of 15 cases of patient with transitional cell in carcinoma of bladder. Avidin-Biotin complex(ABC) kits(Cambridge Research Lab.) and URO-9 and URO-10 monoclonal antibodies were used and the data observed were analyzed. The results obtained were summarized as follows: 1. URO-9 expression was none of 10 fetal bladder mucosae and 3 or 10 normal bladder mucosae and URO-10 expression was none showed. 2. Of 15 cases with transitional cell carcinoma of bladder, URO-9 expression was 5, of which 1 was Ta grade II, 1 T1 grade II and the rest T2 grade III. URO-10 expression was 10, of which I was T1 grade III, 3 T2 grade III, 3 T3 grade III and 3 T4 grade III, of 15 cases of transitional cell carcinoma of bladder. As above results, the transitional cell carcinoma of bladder in low grade and low stage have tendency to express URO-9 monoclonal antibody but not URO-10 monoclonal antibody, whereas the transitional cell carcinoma of bladder in high grade and high stage were inclined to express URO-10 monoclonal antibody with variable expression of URO-9 monoclonal antibody.
Adult ; Antibodies, Monoclonal* ; Antigens, Surface* ; Autopsy ; Biopsy ; Carcinoma, Transitional Cell ; Child ; Fetus ; Humans ; Mucous Membrane ; Urinary Bladder*

To assess the presence and the severity of renal scarring in primary vesicoureteral reflux (VUR), 11 children (3 girls and 8 boys, 19 kidneys) underwent intravenous pyelography (IVP) and 99m Tc-dimercaptosuccinic acid (DMSA) renoscintigraphy and the following results were obtained : 1. Of 19 kidneys, renal margin was shown in 5(26.3% ) and renal scar was revealed only in 3 (15.8%) on IVP. 2. Renal margin in all ( 100.0% ) and renal scar in 12 (63.1%) of the kidney were revealed on 99m Tc-DMSA renoscintigraphy. 3. On the follow-up ranging from 6 months to 13 years after surgical reconstruction, 8 kidneys showed no reversible improvements in renal scar except one, in which progression of renal scar was noted. We concluded that 99m Tc-DMSA renoscintigraphy is more valuable than IVP in evaluating the degree of renal scar and the renal margin.
Child* ; Cicatrix* ; Female ; Follow-Up Studies ; Humans ; Kidney ; Urography ; Vesico-Ureteral Reflux*

No abstract available.
Pregnancy Rate* ; Pregnancy*

Microform cleft lip is a mild form of incomplete cleft lip, also known as a minimal occult, abortive, forme fruste cleft lip. However, it has no definition and few methods have been reported for its correction. A microform cleft lip is characterized as the incomplete union of the superficial portion of the orbicularis oris muscle. It is more prominent during facial expression than in a resting state. We confined microform cleft lip in our study to the absence of philtral skin change and a contracted position on the top of cupid's bow. During the past 5 years, 17 patients of microform cleft lip were operated on. We corrected the defect of the upper vermilion border and nostril sill with minimal incision, and repaired the underlying lip musculature in superficial discontinuity. Reduction of the widened alar base was performed. Deformed alar cartilage was dissected via rim incision, and suspended in a medial and upper direction with pull-out sutures. The most important thing is precise repair of the superficial portion of the separated orbicularis oris muscle via minimal incision, and it is best to operate after 1-year of age for accurate repair. The results were satisfactory and the parents were also satisfied. The advantages of this procedure are as follows: 1. Less visible, minimal scar on upper lip 2. Simultaneous correction of vermillion notching, deformed cupid's bow and nasal deformity. 3. Eversion of philtral ridge due to tenting effect of horizontal mattress suture 4. Philtral elongation effect by reduction of alar base and Z-plasty of cupid's bow.
Cartilage ; Cicatrix ; Cleft Lip* ; Congenital Abnormalities ; Facial Expression ; Humans ; Lip ; Microfilming* ; Parents ; Skin ; Sutures

It was reported that muscle-scleral tuck with nonabsorbable suture material helps to preserve anterior ciliary artery circulation and to prevEnt anterior segment ischemia. The authors measured maximum adhesion power and obsesved histopathologic findings at 1st, 2nd, 4th, and 8th week following a muscle-scleral tuck procedure with absorbable suture material in rabbits. Maximum adhesion powers were increasing with time, 110, 120, 150, and 250gm at each week respectively, and kept enough tension for using absorbable suture material Histopathologic findings demonstrated that inflammatory and foreign body reactions decreased with time, and collagen fibers were proliferated at muscle scleral contact area, and fibers in muscle and sclera connected each other and formed firm adhesion. We concluded that muscle-scleral tuck with absorbable suture material maintained adhesion power enough as a rectus muscle strengthening procedure.
Ciliary Arteries ; Collagen ; Foreign Bodies ; Ischemia ; Muscles* ; Rabbits* ; Sclera ; Sutures*

Summary: Forty three cases of the pigmentary degeneration of the retina (P.D.R.) visited N.M.C. from Nov. 1958 to Sept. 1964 were analysed clinically in regard to various factors which were also based on a review of litrature. The results of the study include following findings. 1. Among 43 cases, retinitis pigmentosa binocular were the largest (25), Laurens-Moon-Biedl Syndrome (3), Macular Involvement (2), Retinitis Pigmentosa sine pigment (2), Retinitis Pigmentosa monocular (1). 2. 6-15 years group is exceedingly largest in regard to the age of the onset. 3. Male is exceedingly prevalent (32) than female(11). 4. 51-60 years old group is the largest in regard to the duration of illness. 5. The known cases through the family history was only 10. The mode of heredity seems to be rather prevalent as recessive than dominant but the group is too small to make a definite decision. 6. Pigmentary deposits in the retina was the largest in regard to the ophthalmoscopic findings. Coneen tric contraction is the the largest as to the visual field changes. 7. Cataract is the largest (24 cases), myopia (12 cases) in the next, as to the complications. 8. As to the symptoms of the Laurens-Moon-Biedl Syndrome, Obecity, Retinitis Pigmentosa, and Mental retardation is found in all cases, but Polydactly in 2 cases, and Genital dystrophy in 1 case. None of cases were specifically related to this disease through the family history.
Cataract ; Heredity ; Humans ; Intellectual Disability ; Male ; Myopia ; Retina* ; Retinitis Pigmentosa ; Telescopes ; Visual Fields

BACKGROUND: Epidurally administered clonidine represents an approach to control the pain after cesarean section that produces analgesia by an alpha 2-adrenergic mechanism and may provide postoperative analgesia without nausea, pruritus, and respiratory depression associated with systemic or intraspinal opioid administration. This study was undertaken to evaluate the analgesic effect according to the dose of appropriate bolus and the combination of epidural morphine and clonidine after cesarean section. METHOD: Forty five women, ASA physical status 1 or 2, scheduled for elective cesarean section were randomly assigned to receive epidural administration for postoperative pain control. Group A (n=15) received 1 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 150 g clonidine. Group B received 2 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 300 g clonidine. Group C received 3 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 450 g clonidine. Each combination of drug was injected at Bromage scale 1 after surgery. RESULTS: All groups showed relatively stable hemodynamic status. Analgesic effect was significantly better in Group B and C than Group A (p<0.05). Sedative effect was not a problem in all groups. The incidence of side effects in Group C was more than Group B, which than Group A, but almost cases did not require treatment. CONCLUSION: 2 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 300 g clonidine with excellent analgesic effect and less side effects is considered as adequate dose in postoperative pain control after cesarean section with epidural anesthesia.
Analgesia ; Anesthesia, Epidural* ; Cesarean Section* ; Clonidine* ; Female ; Hemodynamics ; Humans ; Hypnotics and Sedatives ; Incidence ; Morphine* ; Nausea ; Pain, Postoperative ; Pregnancy ; Pruritus ; Respiratory Insufficiency