To determine the concentration and the physiologic role of metal components in blood plasma and seminal plasma in relation to male infertility, the concentrations of twelve metal components in blood plasma and seminal plasma including Na, Mg, K, Ca, Cr, Mn, Fe, Cu, Zn, Se, Cd and Pb were measured by atomic absorbance spectrophotometery or ion selective electrode analysis. Semen and blood samples were obtained from a total of 110 men including 70 male infertility patients, 20 vasectomized persons and 20 fertility proven volunteers visited to the Male Infertility Clinic of Pusan National University Hospital. The concentrations of Ca, Zn, Mg, Cr and Cd in control group were higher in seminal plasma than in blood plasma, and additionally Pb were higher in infertility group. The concentrations of all metal components revealed no significant difference according to patients' age, resident, occupation, sperm density, motility and hormone level in blood plasma, but some metal components including Ca, Mg, Cu, Mn, Cd and Pb revealed a significant difference according to each these parameters except patient's age in seminal plasma. The concentrations of Mn, Cd and Pb in the vasectomy persons were higher than in the infertility group III including testicular and epididymal factors, but not in blood plasma. We conclude that the quantitative changes of metal components in the seminal plasma may have effects on not only spermatogenesis and sperm function, but also contribute to diagnostic parameter according to organ specificity of the metal in the male reproduction.
Busan ; Electrodes ; Fertility ; Humans ; Infertility ; Infertility, Male ; Male* ; Occupations ; Organ Specificity ; Plasma ; Reproduction ; Semen* ; Spermatogenesis ; Spermatozoa ; Vasectomy ; Volunteers

In these days, there are two main ways in the treatment of the avascular necrosis of the femoral head in adult by prosthetic replscement; total hip replacement and bipolar endoprosthesis. So far, no study has been performed on the post-operative functional evaluation of them. Therefore it is difficult to decide which one is preferred to the other in the treatment of avascular necrosis of the femoral head in adult. In order to evaluate the functions of the prosthetic joints, the authors reviewed the results of 18 cases of cementless bipolar endoprosthesis(abbreviated as CBE) and 22 csses of cementless total hip replscement arthroplasty(abbreviated as CTHRA), performed at the Department of Orthopedic Surgery, Seoul National University Hospital, during the period from February, 1984 to May, 1986. The following results were obtained. 1. The average ages of CBE and CTHRA groups at the time of operation were 48.5 years and 37.5 years, respectively. 2. The average follow-ups of CBE and CTHRA were 15.7 months and 30.5 months, respectively. 3. By Meyer's modification of Marcus and Enneking classification, the sverage stages of CBE and CTHRA groups were 3.7 and 4.4 respectively. 4. According to Harris hip rating score system, Harris scores were increased as much as 30.5 in CBE group and 30.6 in CTHRA group. 5. In the aspects of functional improvement and relief of pain, the two groups showed no significant difference. However, the operation was essier, and the damage to the acetabular bone was less in CBE group. For these reasons, CBE was believed to be the preferred choice of treatment of avascular necrosis of femoral head in adult.
Acetabulum ; Adult ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Classification ; Follow-Up Studies ; Head ; Hip ; Humans ; Joints ; Necrosis ; Orthopedics ; Seoul

No abstract available.
Antibodies, Neutralizing* ; Feces* ; Rotavirus*

This study was carried out to investigate the localization and change of the cell surface antigens, such as URO-9(Om5) and URO-10 (T43), in transitional cell carcinomas of bladder. The subjects used were normal bladder mucosae of 10 autopsy cases of fetus and 10 biopsy cases of child or adult patients with disease of other organs as controls, and neoplastic tissue of 15 cases of patient with transitional cell in carcinoma of bladder. Avidin-Biotin complex(ABC) kits(Cambridge Research Lab.) and URO-9 and URO-10 monoclonal antibodies were used and the data observed were analyzed. The results obtained were summarized as follows: 1. URO-9 expression was none of 10 fetal bladder mucosae and 3 or 10 normal bladder mucosae and URO-10 expression was none showed. 2. Of 15 cases with transitional cell carcinoma of bladder, URO-9 expression was 5, of which 1 was Ta grade II, 1 T1 grade II and the rest T2 grade III. URO-10 expression was 10, of which I was T1 grade III, 3 T2 grade III, 3 T3 grade III and 3 T4 grade III, of 15 cases of transitional cell carcinoma of bladder. As above results, the transitional cell carcinoma of bladder in low grade and low stage have tendency to express URO-9 monoclonal antibody but not URO-10 monoclonal antibody, whereas the transitional cell carcinoma of bladder in high grade and high stage were inclined to express URO-10 monoclonal antibody with variable expression of URO-9 monoclonal antibody.
Adult ; Antibodies, Monoclonal* ; Antigens, Surface* ; Autopsy ; Biopsy ; Carcinoma, Transitional Cell ; Child ; Fetus ; Humans ; Mucous Membrane ; Urinary Bladder*

No abstract available.
Pregnancy Rate* ; Pregnancy*

Recently transurethral incision of prostate (TUIP) is suggested to be a useful method in treating BPH weighting less 35gm, short prostatic urethra. mild bladder outlet obstruction by cystoscopy, and subjective obstructive symptoms with no concomitant prostate cancer. The therapeutic effects of TUIP is compared with those of transurethral resection of prostate (TURP) in small BPH (less than 35gm in weight). 1. The mean prostatic weight of TUIP group (14 cases) and TURP group (15 cases) was 23.9+/-7.2 gm and 25.3+/-7.1gm, each respectively. 2. Pre-and postoperative average flow rates were 4.1 and 10.3 ml/sec in TUIP group and 2.9 and 13.2 ml/set in TURP group. Pre- and postoperative maximum flow rates (MFR) were 7.4 and 13.0 ml/sec in the former and 5.6 and 19.4 ml/sec in the latter (p<0.01). 3. Voiding time (sec/100 ml) improved from 32.2 to 12.8 sec/100 ml in TUIP group and from 41.2 to 6.5 sec/100 ml in TURP group. The initiation time (sec) was shortened From 8.3 to 2.0 sec in the former and from 6.3 to 4.O sec in the latter. 4. In operative time, TUIP group necessitated 25+/-14 minutes, and TURP group. 52+/-10 minutes (p<0.001). 5. Mean duration of catheterization and hospitalization were 3.9 and 5.3 days in TUIP group, an 5.5 and 7.6 days in TURP group (p>0.05). 6. Improvements in the subjective symptoms were noted in 13 (92.2%) of 14 cases in TUIP group and 12 (80%) of 15 cases in TURP group. 7. In complications, l of hematuria requiring transfusion and 1 of incomplete incision in TUIP group and l of hematuria, 1 of retrograde ejaculation and 1 of urinary incontinence in TUIP group were experienced. In comparison to TURP. TUIP is easier in technique, less invasive with fewer complications and shows improvements in the subjective symptoms. Therefore. TUIP is a useful method in treating small BPH. especially in sexually active patients.
Catheterization ; Catheters ; Cystoscopy ; Ejaculation ; Hematuria ; Hospitalization ; Humans ; Male ; Operative Time ; Prostate* ; Prostatic Hyperplasia* ; Prostatic Neoplasms ; Transurethral Resection of Prostate ; Urethra ; Urinary Bladder Neck Obstruction ; Urinary Incontinence

No abstract available.
Female ; Hydatidiform Mole* ; Pregnancy ; Trophoblasts*

BACKGROUND: Epidurally administered clonidine represents an approach to control the pain after cesarean section that produces analgesia by an alpha 2-adrenergic mechanism and may provide postoperative analgesia without nausea, pruritus, and respiratory depression associated with systemic or intraspinal opioid administration. This study was undertaken to evaluate the analgesic effect according to the dose of appropriate bolus and the combination of epidural morphine and clonidine after cesarean section. METHOD: Forty five women, ASA physical status 1 or 2, scheduled for elective cesarean section were randomly assigned to receive epidural administration for postoperative pain control. Group A (n=15) received 1 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 150 g clonidine. Group B received 2 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 300 g clonidine. Group C received 3 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 450 g clonidine. Each combination of drug was injected at Bromage scale 1 after surgery. RESULTS: All groups showed relatively stable hemodynamic status. Analgesic effect was significantly better in Group B and C than Group A (p<0.05). Sedative effect was not a problem in all groups. The incidence of side effects in Group C was more than Group B, which than Group A, but almost cases did not require treatment. CONCLUSION: 2 mg morphine and 75 g clonidine bolus followed by 4 mg morphine and 300 g clonidine with excellent analgesic effect and less side effects is considered as adequate dose in postoperative pain control after cesarean section with epidural anesthesia.
Analgesia ; Anesthesia, Epidural* ; Cesarean Section* ; Clonidine* ; Female ; Hemodynamics ; Humans ; Hypnotics and Sedatives ; Incidence ; Morphine* ; Nausea ; Pain, Postoperative ; Pregnancy ; Pruritus ; Respiratory Insufficiency

IgE-mediated sensitization to natural rubber latex can induce immediate hypersensitivity reactions ranging from contact urticaria to life threatening anaphylaxis. Recent reports suggest that asthma is also relatively frequent manifestation of latex allergy. In this case report, lat,ex induced asthma is described in an operat.ing room nurse regularly exposed t,o latex gloves. Her latex sensitivity was detected by skin prick testing. Specific bronchial provocation test with latex extract showed an early asthmatic reaction. Her symptoms had been much improved after avoidance. Occupational asthma induced by latex may be not uncommon among health care workers.
Anaphylaxis ; Asthma ; Asthma, Occupational* ; Bronchial Provocation Tests ; Delivery of Health Care ; Humans ; Hypersensitivity, Immediate ; Latex ; Latex Hypersensitivity ; Personnel, Hospital* ; Rubber ; Skin ; Urticaria

Microform cleft lip is a mild form of incomplete cleft lip, also known as a minimal occult, abortive, forme fruste cleft lip. However, it has no definition and few methods have been reported for its correction. A microform cleft lip is characterized as the incomplete union of the superficial portion of the orbicularis oris muscle. It is more prominent during facial expression than in a resting state. We confined microform cleft lip in our study to the absence of philtral skin change and a contracted position on the top of cupid's bow. During the past 5 years, 17 patients of microform cleft lip were operated on. We corrected the defect of the upper vermilion border and nostril sill with minimal incision, and repaired the underlying lip musculature in superficial discontinuity. Reduction of the widened alar base was performed. Deformed alar cartilage was dissected via rim incision, and suspended in a medial and upper direction with pull-out sutures. The most important thing is precise repair of the superficial portion of the separated orbicularis oris muscle via minimal incision, and it is best to operate after 1-year of age for accurate repair. The results were satisfactory and the parents were also satisfied. The advantages of this procedure are as follows: 1. Less visible, minimal scar on upper lip 2. Simultaneous correction of vermillion notching, deformed cupid's bow and nasal deformity. 3. Eversion of philtral ridge due to tenting effect of horizontal mattress suture 4. Philtral elongation effect by reduction of alar base and Z-plasty of cupid's bow.
Cartilage ; Cicatrix ; Cleft Lip* ; Congenital Abnormalities ; Facial Expression ; Humans ; Lip ; Microfilming* ; Parents ; Skin ; Sutures