The effect of saponin on the Na+ - K+ ATPase of anterior capsule and epithelium of cattle lens has been investigated. The experiment also designed to determine the cation of saponin on the Na+ - K+ ATPase activity in anterior capsule and epithelium of cattle lens. The following results are observed. 1. The Na+ - K+ ATPase activity of cattle lens epithelial cell membrane is inhibited by low concentration of saponin, but increased by high concentration. The strongest activity showed at the dose of 50mg% saponin concentration. 2. The activating effect of saponin on the cattle epithelial cell membrane Na+ - K+ ATPase activity is inhibited by ouabain, but the stimulation of the Mg++ ATPase by high concentration of saponin is not inhibited by ouabain. 3. The activity ratio of Na+ - K+ ATPase by high concentration of saponin is increased by raising the sodium concentration but decreased by raising the potassium concentration. 4. The Na+ - K+ ATPase activity is increased by small amount of calcium but completely inhibited by over 5mM concentration of calcium.
Adenosine Triphosphatases* ; Animals ; Calcium ; Cataract ; Cattle* ; Epithelial Cells* ; Epithelium ; Membranes ; Ouabain ; Potassium ; Saponins* ; Sodium

BACKGROUND: There has been a change in the causes of aortic stenosis when comparence of rheumatioc aortic stenosis in recent year. Therefore, we studied the etiology factor of pure aortic stenosis. METHODS: The gross surgical pathologic features of the aortic valves were reviewed in 92 patients with pure aotic stenosis whom underwent aortic valve replacement at Yonsei University, Cardiovascular center between July 1989 and June 1994. RESULTS: The three most frequent causes were 1) calcification of congenital bicuspid valve in 30%, 2) degenerative calcification of aortic valve in 22%, 3) rheumatioc valvular change in 48%. The mean age at the time of aortic valve replacement for the entire series of patients was 54.4 years. The range of age was from 18 years to 77 years. Males predominated for degenerative disease and congenital bicuspid valves, but there were reversed rheumatic origin. One or more complications occured in 17% of patients undergoing operation. The surgical mortality was 3.3%. CONCLUSION: Our data suggest that more common cause of aortic stenosis is non-rheumatic disease rather than rheumatinc origin.
Adult* ; Aortic Valve ; Aortic Valve Stenosis ; Constriction, Pathologic* ; Humans ; Male ; Mitral Valve ; Mortality

No abstract available.
Abscess*

No abstract available.
Aspirin* ; Epithelial Cells*

Authors experienced a case of a huge intrathoracic teratoma in the right uppet mediastinum in male 7 months of age who had dyspnes of 1 month of duration, which was aggravated with cough and fever, and cyanosis 2 days prior to admission. He was relieved dramatically by open chest surgery, resecting the tumor measured 8X5X5 cm. The review of literatures was made.
Cough ; Cyanosis ; Fever ; Humans ; Male ; Mediastinum ; Teratoma* ; Thorax

This paper represents the clinical observations including the causes of admission and of deaths in pediatric age admitted during Jan. 1971 to Dec. 1975, into the pediatric ward of St. Paul's Hospital, Catholic Medical College located in the east zone of Seoul, covering the middle socio-economical classes in the regional and suburban populations. The results obtained were as follows: 1. Total admissions during 5 year-period were 2005, with the ratio of male to female 1.63/1. 2. In age distribution, the neonates and the infants less than 1year of age occupied 47.5%of total admissions and 65.9% of total deaths. 3. Major leading diseases of admission were bronchitis and pneumonia, gastroenteritis, pre-maturity, tuberculosis and upper respiratory tract infections, in order of incidence. 4. Total deaths were 129 and the mortality rate was 6.4%. 5. Major leading causes of deaths were pneumonia, pre-maturity, tuberculosis, septicemia, in order of incidence. The diseases of higher fatality rate were idiopathic respiratory distress syndrome, septicemia, encephalitis and encephalopathy, birth trauma and heart disease. 6. The death occurred within 48 hours after admission was 65.9% of total deaths.
Age Distribution ; Bronchitis ; Cause of Death ; Encephalitis ; Female ; Gastroenteritis ; Heart Diseases ; Humans ; Incidence ; Infant ; Infant, Newborn ; Inpatients* ; Male ; Mortality* ; Parturition ; Pneumonia ; Respiratory Tract Infections ; Seoul ; Sepsis ; Suburban Population ; Tuberculosis

No abstract available.
Aneurysm*

This study has been examined different morphologic measurements in the evaluation of patients with lumbar spinal stenosis. Preoperative CT-Myelography from 30 patients who underwent surgery for central lumbar stenosis were analyzed. Based on this, we concluded as follows : 1) Bony measurement alone did not reliably identify patients with spinal stenosis. 2) Measurement of the transverse area of the dural sac on CT-Myelography was the most accurate method for identifying stenosis. 3) Lumbar myelography was still considered to have an important role in the valuation of a patient with stenosis because of correlation between the cross-sectional area of the dural sac and the anteroposterior diameter of the dural sac was excellent. 4) We identified soft-tissue problems as the main cause of stenosis. 5) The most common level of maximum stenosis was L4-5.
Constriction, Pathologic ; Humans ; Myelography* ; Spinal Stenosis*

Two cases of Reye's syndrome in an age of 14months and a 3 years female were observed. The laboratory findings revealed increased SGPT, SGOT and hypoglycemia, respectively. Clinical findings were also compatable with this syndrome. In one case, liver biopsy revealed fatty infiltration of the liver cells. A brief review of related literatures was presented.
Alanine Transaminase ; Aspartate Aminotransferases ; Biopsy ; Female ; Humans ; Hypoglycemia ; Liver ; Reye Syndrome*

No abstract available.
Heart Arrest, Induced* ; Oxygen*