Transcatheter arterial chemoembolization(TACE) is an imperative method for the managment of inoperable hepatocellular carcinoma(HCC). It is well known that primary HCC frequently invades the portal venous system and forms a tumor thrombus obstructing the portal blood flow which makes unfavorable prognosis of patiebt. We retrospetively reviewed 58 patients who reveived TACE(minimum 3 times) of HCC invading into portal venous system. Group 1(n=29) which showed peripheral portal vein invasion had better clinical and laboratory response. Group 2(n=17) which showed first order portal branch invasion had similar response to Group 3(n=12), which had main portal invasion. Group 1 showed no difference in survival time between TAC and TACE, but, in Group 2 and 3, emboliation with chemotherapy made longer survival than chemotherapy only. Clinical level of AFP was meaningful in Group 1 and 2 as decreasing value. Our results provides that careful selection of TACE and case by case Coil/Gelfoam embolization can improve the mean survival and clinical response when HCC evidently invades portal venous system.
Carcinoma, Hepatocellular* ; Drug Therapy ; Humans ; Methods ; Portal Vein* ; Prognosis ; Thrombosis

Transcatheter arterial chemoembolization(TACE) is an imperative method for the managment of inoperable hepatocellular carcinoma(HCC). It is well known that primary HCC frequently invades the portal venous system and forms a tumor thrombus obstructing the portal blood flow which makes unfavorable prognosis of patiebt. We retrospetively reviewed 58 patients who reveived TACE(minimum 3 times) of HCC invading into portal venous system. Group 1(n=29) which showed peripheral portal vein invasion had better clinical and laboratory response. Group 2(n=17) which showed first order portal branch invasion had similar response to Group 3(n=12), which had main portal invasion. Group 1 showed no difference in survival time between TAC and TACE, but, in Group 2 and 3, emboliation with chemotherapy made longer survival than chemotherapy only. Clinical level of AFP was meaningful in Group 1 and 2 as decreasing value. Our results provides that careful selection of TACE and case by case Coil/Gelfoam embolization can improve the mean survival and clinical response when HCC evidently invades portal venous system.
Carcinoma, Hepatocellular* ; Drug Therapy ; Humans ; Methods ; Portal Vein* ; Prognosis ; Thrombosis

Metaplastic carcinoma is a rare form of breast carcinoma in which a variety of metaplastic changes occur. These commonly involve squamous or spindle cells, but pure chondroid metaplasia is relatively uncommon. We report a case of metaplastic carcinoma of the breast which mainly involved chondroid metaplasia and in which chondroid calcifications were seen on mammograms.
Breast Neoplasms ; Breast* ; Cartilage ; Metaplasia

PURPOSE: Surgical excision of the subcutaneous tissues, with or without skin excision in the axillary hair-bearing area, has been the treatment of choice in treating osmidrosis for several decades. However, long periods of postoperative immobilization of a shoulder joint, partial necrosis of skin flaps or the possibility of hematoma and scars have occurred frequently. So we used XPS(R) microresector(Shaver) in procedure which requires removal of soft tissue for comparing results between surgical excision and the laters. METHODS: From January 2007 to February 2008, a total of 20 patients(8 male and 12 female) underwent XPS(R) microresector(Shaver) assisted aspiration for treating osmidrosis. The mean age of the subjects was 21.9, and we tried to analyze some advantages of XPS(R) microresector(Shaver). RESULTS: The average operation time was 61.6 minutes. This results can show that the patients who received XPS(R) microresector(Shaver) assisted aspiration can accomplish better outcomes than any other procedures in terms of operation time at least. Moreover, no significant postoperative complications occurred in our studies. Subjects have been followed up from 2 months to 1 year and among these patients, no one suffered from critical complications. CONCLUSION: In brief, XPS(R) microresector(Shaver) is able to shorten the time of operation and simplify the procedures relatively and this device has more superiorities in wound healing by maintaining of vascularized dermal skin flaps. It means that XPS(R) microresector (Shaver) can prevent flap necrosis, axillary hair loss and minimalize scarring and bleeding. Thus, we expect that these advantages can lead to better patient's comfort and self-confidence than several previous procedures.
Cicatrix ; Hair ; Hematoma ; Hemorrhage ; Humans ; Immobilization ; Male ; Necrosis ; Postoperative Complications ; Shoulder Joint ; Skin ; Subcutaneous Tissue ; Wound Healing

Langerhans cell histiocytosis (LCH), previously called histiocytosis X, refers to a spectrum of disease characterized by idiopathic proliferation of histiocytes producing focal or systemic manifestations. Causes and pathogenesis remain unclear. The basic histopatholgic findings are identical in the three well-established clinical syndromes (eosinophilic granuloma, Hand-Shuller-Christian disease, Letterer-Siwe disease). The disease has a predilection for children, although it may occur in adults. We experienced two cases of adult onset Langerhans cell histiocytosis in the ribs. One case was associated with diabetes insipidus and the other case had a solitary lesion.
Adult* ; Child ; Diabetes Insipidus ; Granuloma ; Histiocytes ; Histiocytosis ; Histiocytosis, Langerhans-Cell* ; Humans ; Ribs*

PURPOSE: To determine the degree and effect of contrast enhancement of the hepatic parenchyma according to different injection rates, amounts and types of contrast materials. MATERIALS AND METHODS: A total of 270 patients were divided into nine groups. Each group received different volumes(120, 130, or 140ml) and was scannedwith different injection rates of 2, 3 or 4 ml/sec. Three kinds of contrast materials(Ultravist 370, Iopamiro 370, Optiray 320) were used. Hepatic enhancement was measured by comparing quantitative regions of interest(ROI) beforeand after bolus injection of contrast material which were evaluated on arterial, portal and delayed phase duringdouble spiral scanning. RESULTS: There was no significant statistical difference in contrast enhancement between the three kinds of contrast materials. In noncirrhotic patients, hepatic enhancement was greatest on portal phase and was greater at a rate of 4ml/sec than 2ml/sec or 3ml/sec on arterial phase. At the same injection rate, thevolume of contrast material was an important factor on portal and delayed phase. In the cirrhotic patients, Child's C showed more delayed peak enhancement than did Child's A. CONCLUSION: The important factors in contrast enhancement were injection rate on arterial phase and volume on portal and delayed phase. The optimal choice mustbe made after considering intrinsic variables ; in addition, our results are helpful for determining enhancement protocol during double spiral CT scanning.
Contrast Media ; Humans ; Iopamidol ; Liver* ; Tomography, Spiral Computed*

Clinicostatistical study was carried out on 130 cases of children with malignant tumors admitted in pediatric ward of Severance Hospital from 1965 to 1974 and the following results were obtained: 1) The incidence of malignancies on all admitted cases was 1.0% and males were more affected(68.5%) than females. 2) The annual increase of incidence on childhood malignancies couldn't be observed. 3) The highest incidence of malignancies (50.0%) was noted in preschool age group of children (1~6 Yrs). 4) The most common malignancy was leukemia (59.1%) and tumors arising from neural origin were next common. 5) The common sites of organ involvement by malignancies were RES including blood (77 cases), brain (17 cases) and sympathetic nerve (14 cases) in order of incidence. 6) The tentative diagnosis of malignancy was made on 80.8% of all cases at the time of admission. 7) Anemia and bleeding tendency were main problems in leukemic children (40 casse) on admission and mass or abdominal distension in the children with neuroblastoma, lymphoma and hepatoma. 8) Mean admission days of children with malignancy were 2 weeks and 20% of all cases were died in the hospital. 28.5% of all cases were improved at the time of discharge and 19.2% wree discharged against advice.
Anemia ; Brain ; Carcinoma, Hepatocellular ; Child* ; Diagnosis ; Female ; Hemorrhage ; Humans ; Incidence ; Infant* ; Leukemia ; Lymphoma ; Male ; Neuroblastoma

No abstract available.
alpha-Tocopherol* ; beta Carotene* ; Humans ; Retinoids*

PURPOSE: To analyze the clinical results of the treatment of Mason type II radial head fractures using closed reduction and K-wire internal fixation under C-arm guide by radiologically and functionally. MATERIALS AND METHODS: Between March 2001 and October 2003, 7 patients with Mason type II radial head fracture were treated by closed reduction and internal fixation using K-wires under C-arm guide. The average age of the patients was 38 (5 to 57) years old, and average duration of follow up was 20 (5 to 36) months. At last follow up, we evaluated the radiological results and functional results by classifying excellent, good, fair and poor according to functional rating system of Broberg and Morrey. RESULTS: The range of motion of the elbow at last follow up, average flexion contracture was 1.4 (0 to 10) degrees, further average flexion was 146.4 (140 to 150) degrees, average supination was 74.2 (70 to 80) degrees and average pronation was 75 (70 to 80) degrees. In the functional results, 6 cases were excellent and 1 case was good. In the radiological evaluations, the average time of union was 5 (4 to 6) weeks after the operation and no serious complication was occurred in any cases. CONCLUSION: In the treatment of Mason type II radial head fracures, closed reduction and K-wire internal fixation under C-arm guide was an effective method of treatment with satisfactory results and no complications.
Contracture ; Elbow ; Follow-Up Studies ; Head* ; Humans ; Pronation ; Range of Motion, Articular ; Supination

PURPOSE: To evaluate the efficacy of this operative method, which includes removal of infected materials, insertion of a bone graft and fixation with pedicle screws through a posterior-only approach in spondylitis with advanced bone destruction and radicular pain. MATERIALS AND METHODS: Ten patients with refractory single level spondylitis of the lumbosacral spine, who underwent the above operation and were followed-up for more than 2 years, were analyzed retrospectively. Six cases were tuberculous and 4 cases were pyogenic in etiology. Radiologically, bone union and restoration of sagittal alignment were assessed. Clinically, Visual Analog Scales (VAS) for back pain, leg pain and resolution of neurologic symptom were analyzed. RESULTS: Bone union was achieved in all cases. Sagittal angle was corrected significantly from -3.6+/-12.5 degrees to -11.4+/-9.3 degrees (p=0.007). However, loss of correction was noted from -16.2+/-10.2 degrees at immediate after surgery to -11.4+/-9.3 degrees at last follow-up (p=0.005). Back pain VAS was improved from 8.3+/-0.7 to 2.6+/-1.6 (p=0.005) and leg pain VAS was improved from 6.8+/-2.1 to 0.5+/-0.9 (p=0.005). There was strong positive correlation between age and final back pain (r=0.79, p=0.011) and leg pain VAS (r=0.75, p=0.020). There was no meaningful correlation between the sagittal angle and back pain (r=0.30, p=0.430) and leg pain VAS (r=0.41, p= 0.274). Implant related complications and deep wound infections did not occur. CONCLUSION: In single level spondylitis of the lumbosacral spine, a posterior-only surgical approach is a useful method in which debridement, bone graft placement and pedicle screw fixation can be performed. This procedure did not provide increased risk with respect to infection control, and it allowed correction of the sagittal angle. The younger the age of the patients, the better the back pain and leg pain VAS results.
Back Pain ; Debridement ; Follow-Up Studies ; Humans ; Infection Control ; Leg ; Neurologic Manifestations ; Retrospective Studies ; Spine ; Spondylitis* ; Transplants ; Visual Analog Scale ; Wound Infection