One hundred and twenty male rabbits were divided into 8 groups in order to studythe effect of castration and sex hormone administration on water and electrolytesdistribution in kidney, small intestine and lung tissue as follows:Group 1: control (non castrated)Group 2: estrogen injectedGroup 3: androgen injectedGroup 4: progesterone injectedGroup 5: castration control (castrated)Group 6: estrogen injected and castrationGroup 7: androgen injected and castrationGroup 8: progesterone injected and castrationFourteen days after castration, each rabbit in groups 6, 7 and 8 was administeredwith 2,000 units of estrogen, 400 units of androgen and 400 units of progesteronddaily for 3 days consecutively. Three days after the final injection, they weresacrificed by means of cardiac puncture. Immediately after sacrificing the animals, kidney, lung and small intestine were removed to determine the contentsof tissue water. Na, K and Cl. Water content was determined by drying method in 1O0 degrees C oven until the weight remained constant. Na and K in serum and tissue wereanalyzed with Baird flame photometer using lithium nitrate as internal standard.Serum Cl was analyzed by the method of Schales and Schales and tissue Cl by theVan Slyke's. The conclusion is as follows: 1) In control rabbits (non castrated), serum concentration of Na and K was decreased while Cl concentration was increased after administration of estrogen, androgen and progesterone. 2) In castrated rabbits, serum concentration of Na was increased, while K was decreased. Na and K were decreased, while Cl was increased by the administration of sex hormone after castration. 3) In kidney tissue of non castrated rabbits, water content was slightly increased by the administration of sex hormone. The changes in concentration of Na, K, Cl. extracellular space and total Na + K were not significant, while K was increased remarkably in the progesterone group. Also the total Na + K [cell water (Na)] was remarkably increased as high as 47%. 4) In kidney tissue of castrated rabbits, water content and Na were increased, whereas K and Cl were decreased. The administration of sexhormone acted inclusively on the restoration of these levels to the precastration state. The androgen injection provided the most effective result. 5) In lung tissue of non castrated rabbits, Na and K were decreased by the administration of sex hormone. In the androgen group, a decrease of Na and K was most remarkable, Cl in the progesterone group, and Na space and total Na+K in the androgen group were decreased remarkably. 6) In lung tissue of castrated rabbits, water content was increased, and Na, K and Cl were all decreased. The administration of sex hormone acted inclusively on the restoration of these levels to the precastration state. In general, the androgen was most effective among hormones given. 7) In small intestine tissue of non castrated rabbits, Na, K and Cl were increased and also the extracellular space and total Na+K were inclusively increased. 8) In small intestine tissue of castrated rabbits, water content and K were increased while Na was decreased. The administration of sex hormone acted on the restoration to the precastration state in the water content and Na. The androgen was most effective among hormones given.
Animals ; Castration* ; Estrogens ; Extracellular Space ; Humans ; Intestine, Small ; Intestines* ; Kidney* ; Lithium ; Lung* ; Male* ; Progesterone ; Punctures ; Rabbits ; Smell*

To use basic data for health planning and evaluation of Kangwha community health project of Yonsei University, a study on death rates and causes of death were investigated in two townships (Naega and Sunwon Myuns) in Kangwha County from April 1, 1975 to March 31, 1977). All death was identified and reported by family health workers who are living in each village and 2 trained public health nurses confirmed the death. The causes of death were investigated by 2 public physicians. Total number of deaths for 2 years was 230 and the followings are brief summary of the study. 1. Age-adjusted crude death rates of study area were 8.69 per 1,000 population in 1975 and 7.18 per 1,000 population in 1976. Age-adjusted crude death rates for male were 9.18 in 1975 and 6.38 in 1976 and for female were 8.33 and 7.80 per 1,000 population. 2. Age specific death rate curves by year and sex showed "U" shapes. 3. Infant and neonatal death rates were 30.08 and 22.56 per 1,000 live births in 1975, and the rates in 1976 were 18.18 and 13.64. 4. The most common cause of death was cerebrovascular disease and average cause specific death rate for the disease was 215.5 per 100,000 population. 5. Four leading causes of death were non-infectious origin ; cerevrovascular disease, malignant neoplasms, senility and suicide. Pulmonaty tubeculosis and pneumonia occupied 5th and 9th causes of death. 6. Stomach cancer and hepatoma occupied 61.3% of total death due to malignant neoplasms. 7. Most frequent cause of neonatal death was birth injury. Two deaths due to tetanus were found in 1975, but no death due to this disease was found in 1976. 8. About half of deceased received care from physician before death.
Birth Injuries ; Carcinoma, Hepatocellular ; Cause of Death* ; Family Health ; Female ; Health Planning ; Humans ; Infant ; Live Birth ; Male ; Mortality* ; Nurses, Public Health ; Pneumonia ; Stomach Neoplasms ; Suicide ; Tetanus

No abstract available.
Gallbladder*

Numerous cicatrizing and granulomatous diseases that simultaneously involve choroid, retina and their intervening Bruch's membrane may cause choroidoretinal vascular anastomoses. Anastomoses at capillary level and in neovascular granulomatous tissue are probably not uncommon under these and related circumstances, but choroidal connections to large-caliber segments of otherwise normal retinal arterioles and venules are unusual. We retrospectively studied 44 eyes of 44 patients with choroidal ruptures after blunt trauma. Of 44 choroidal ruptures, three patients had chorioretinal ruptures and choroidoretinal vascular anastomoses. This report describes three cases of large-caliber choroidoretinal anastomoses after chorioretinal ruptures.

We experienced four patients that had gone unreduced for at least eight weeks and evaluated the results of the operative treatment in these paitents. All four cases were anterior dislocation, and among them three cases were dislocated by direct trauma and one was dislocated during seizure attack. Pain was moderate in one case and mild in three cases. In the preoperative range of motion, the average passive tlexion at the scapular plane was 143 degrees (90 degrees - l70 degrees) and average external rotation at the side was 33 degrees(5 degrees-60 degrees), but the average active flexion was 103 degrees, active external rotation was 16 degrees and the internal rotation at the back was the sacral level except one. All four patients complained of severe limitation of daily living activity due to limitation of motion and weakness and could not occupy their jobs. In all four cases, three dimensional CT scan was performed to evaluate glenoid and humeral bone defect and for preoperative planning. Operation was performed at 8 weeks after initial dislocation in two cases, 1 year later in one case and 2 years later in one case. Open reduction was done and the defect of humeral head was filled with osteochondral allograft in two cases. Fractured humeral head fragment was reduced and fixated with non-ahsorhahle suture in one case and prosthetic head replacement was performed in the other. As a result, three patients had a mild or moderate pain postoperatively and moderate functional restrictions in the activities of daily living, and they were considered to be unsatifactory. Two cases were subluxated during the follow-up. These results show that the overall prognosis for the surgical treatment of the chronic unreduced dislocated shoulder is unpredictable and unacceptable.
Activities of Daily Living ; Allografts ; Dislocations* ; Follow-Up Studies ; Head ; Humans ; Humeral Head ; Prognosis ; Range of Motion, Articular ; Seizures ; Shoulder* ; Sutures ; Tomography, X-Ray Computed

Congenital syphilis is transmitted throuth the placenta by the infected mother after 16 weeks of gestation.Since the incidence of syphilis is again on the increase, syphilis remanis at the present time a public problem ofmajor and increasing proportions. Recently, congenital syphilis has different formas of presentation. The authorsobserved clinically and radiologically 27 cases of congenital syphilis in the neonates and infants treated at thepediatric ward of Chonnam National University Hsopital from Jan. 1977 to Mar. 1982. The results are as follows; 1.The number of observed patients was 27 cases, 22 cases in male, 5 cases in female. 2. Onset of first clinicalsymptoms and signs was within the 4th week life in 14 cases (52%), 1-2 months in 6 cases (22%), 2-3 months in 4cases (15%), 3-4 months in 3 cases (11%). All cases was within 6 months. 3. The order of the frequency of commonclinical manifestations was hepatomegaly (96%). splenomegaly (78%), skin lesions(63%), anemia(63%), nasalsnuffle(56%). 4. Of 11 cases with known birth weight, 10 cases were low birth weight. 5. The serologic test (VDRLslide test) of 27 tested cases revealed reactive response in 26 cases, nonreactive response in 1 case, and that ofsyphilitic mothers except one revealed reactive in 23 cases, non-reactive in 3 cases. 6. Roentgenographicsyphilitic bonychanges were detected in 26 cases (96%), of 27 studied cases, Osteochondritis was present in 24cases (89%), periostitis in 21 cases (78%), osteomyelitis in 11 cases(41%). 7. The most common sites affected wereas follows. Radius and ulna were the most frequently affected, the next were in order of tibia and fibula.Considering osteochondiritis only, the distal end of radius and ulna(78% respectively) and proximal end of tibia(67%) were the most frequently affected sites, the proximal en of femur (33%) was least frequently affected site.8. On chest films of 27 cases, osseous chanages(Mainly periostitis) of clavicle were noted in 14 cases and thoseof rib in 2 cases.
Birth Weight ; Clavicle ; Female ; Femur ; Hepatomegaly ; Humans ; Incidence ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; Jeollanam-do ; Male ; Mothers ; Osteochondritis ; Osteomyelitis ; Periostitis ; Placenta ; Radius ; Ribs ; Serologic Tests ; Skin ; Splenomegaly ; Syphilis ; Syphilis, Congenital ; Thorax ; Tibia ; Ulna

The capillary hemangioblastoma, as originally defined by Lindau and by Cushing and Bailey, is widely regarded as being of Vascular origin and relatively uncommon. The most frequent site of this neoplasm is the cerebellum and second frequency is the spinal cord. We experienced a case of capillary hemangioblastoma arising at the upper thoracic spinal cord with the paraplegia and the sensory disturbance below the nipple line. The total laminectomy with mass excision was taken and the patient have shown good improvement of the neurological defecits in postoperative period.
Capillaries ; Cerebellum ; Hemangioblastoma ; Humans ; Laminectomy ; Nipples ; Paraplegia ; Postoperative Period ; Spinal Cord

Supracondylar fractures of the femur following total knee arthroplasty are rare complication with reported rates ranging from 0.3% to 2.5%. Union of the fracture in proper alignment, without disruption of prosthetic component fixation and with maintenance of 90 of knee motion, is impotant in treatment of this type of fracture. Modalties of treatment are conservative or operative methods and operative treatment are open reduction 4 internal fixation, intramedullary nailing, revision arthroplasty using a prosthesis with a long stem and closed reduction and external fixation, but there are controversies in the method of treatment. Between Apr. 1989 and Jul. 1994, 10 patients were treated for supracondylar fracture of the ipsilaterai femur following total knee atthroplasty and 2 cases of them had arthrop]asty at other hospital. Average age of patients was 53 years (29-68 years), nine patients were women and one was man. The preoperative diagnosis was rheumatoid arthritis in four, degenerative osteoaithritis in three, posttraumatic osteoarthritis in one and tuberculosis sequelae of the knee in two. In nine cases mechanism of injury were slip down and in one was fall down. The interval hetween arthroplasty and fracture was an average of 22 months (9-79months). Two cases we.re treated with closed reduction and cast immobilization, one case was treated with open eduction and in1ernal fixation and seven patients of' ten cases were treated with closed intramedullay Ender nailing. The average foIlow-up period after fracture was 25 months (3 - 74months). We evaluated the results as the range of motion, bony union at simple radiograph and Knee Rating Score of Hospital for Special Surgery at last follow up. Eight cases of supracondylar fracture occuned among 350 patients, 514 cases of total knee arthroplasty which were operated at Kyung Hee Univcrsity Hospital between Apr. 1989 and Jul. 1994 and incidence was 1.6%. At the last follow up, all 10 cases achieved bony union and 7 cases using Ender naiIing achieved clinical bony union which enabled patients to do weight-bearing without pain at postoperative 6-8 weeks and radiological union was achieved at postoperative 12 weeks. Range of motion were average 105 degrees (80 J.20 degrees) hefore fracture and 86 degrees (6S 120 degrees) at the last follow up and HSS Knee rating score were average 80.3 points (59 94 points) before fracture and average 78.8 points (66-89 points) at the last follow up. At 7 cases using Ender nailing, range of motion were average 106 degrees (90 11S degrees) hefore fracture and 91 degrees (6S-105 degrees) at last follow up and HSS Knee rating score were average 80.6 points (59-94 points) before fracture and average 80.3 points (72-89 poiints) at the last follow up. Closed iintramedullary Ender nailing is a gecommendable operative method in the treatment of supracondylar fracture following total knee arthroplasty considering to good bony union, satisfactory functional result, easy operative technique and less postoperative complication.
Arthritis, Rheumatoid ; Arthroplasty* ; Diagnosis ; Female ; Femur ; Follow-Up Studies ; Fracture Fixation, Intramedullary ; Humans ; Immobilization ; Incidence ; Knee* ; Osteoarthritis ; Postoperative Complications ; Prostheses and Implants ; Range of Motion, Articular ; Tuberculosis ; Weight-Bearing

No abstract available.
Colon* ; Rectum*

PURPOSE: To evaluate the relative value of arterial, portal venous and delayed phase images of spiral CT in the detection of metastatic tumor of the liver. MATERIALS AND METHODS: Forty-three metastatic tumors in twelve patients were underwent tri-phasic spiral CT examination with injection of 120 ml ionic contrast material (36 g of iodine) at the rate of 3 ml/sec. Arterial, portal venous and delayed phase CT images were obtained 35, 65, and 360 seconds after the start of contrast injection, respectively. RESULTS: Arterial phase images detected 35(81%), portal venous phase images 43(100%), and delayed phase images 34(79%) lesions, respectively(p<0.05). All masses larger than 2cm(n=23) were detected in all three phases, whereas 60%, 100%, 55%of the masses smaller than 2cm(n=20) were detected in arterial, portal venous and delayed phase CT, respectively. The best contrast between masses and the hepatic parenchyma was in portal venous phase followed by arterial and delayed phase(p<0.01). In two hypervascular masses, the contrast was better in arterial phase. CONCLUSION: Portal venous phase of spiral CT is optimal in the detection of metastatic tumor of the liver. Arterial phase may be helpful for the detection of hypervascular metastasis. Delayed phase should be used restrictively.
Humans ; Liver* ; Neoplasm Metastasis ; Tomography, Spiral Computed*