No abstract available.
Muscular Atrophy, Spinal* ; Spinal Muscular Atrophies of Childhood*

The pancreatic pseudocyst as a sequela of pancreatitis or pancreatic trauma can occur at any site in the abdomen. Its detection seems to be increasing with modern imaging tools such as abdominal ultrasound or abdominal CT scanning. But recently, we experienced a case of a pseudocyst due to a ruptured pancreatic pseudocyst which was misdiagnosed as a simple hepatic cyst by abdominal ultrasonography or abdominal CT scan. A 12-year-old male presented with recurrent epigastric pain during the past 4 years. On the abdominal ultrasound and abdominal CT scan, there was an 8x7.5 cm sized sharply defined thin-walled cyst in the left lobe of the liver. First, percutaneous (cather) drainage guided by ultrasonography was done. An exploratory laparotomy was performed because of signs of hemoperitoneum. A 8x7.5 cm sized cyst was found at the left subhepatic space, which communicated with another smaller cystic lesion in the pancreatic head. Microscopic finding of the cyst showed infiltration of inflammatory cells and granulation tissue without ephithelial lined cells which is compatible to a pseudocyst. So we report this case with a review of literatures.
Abdomen ; Child ; Diagnostic Errors* ; Drainage ; Granulation Tissue ; Head ; Hemoperitoneum ; Humans ; Laparotomy ; Liver ; Male ; Pancreatic Pseudocyst* ; Pancreatitis ; Tomography, X-Ray Computed ; Ultrasonography

Various reconstructive surgery have been performed for repair of the patellar tendon defect due to direct trauma or infected open wound. But most surgical procedure need wide skin incision and soft tissue dissection, that result in joint stiffness or muscle weakness. We carried out two-stage reconstructive surgery used bone-patellar tendon-bone allograft and bioabsorbable interference screw for skin and patellar tendon defect due to repetitive debridment for infected wound management. The result was satisfactroy and the patient achieved nearly full return of knee motion and quadriceps strength.
Allografts* ; Humans ; Joints ; Knee ; Muscle Weakness ; Patellar Ligament* ; Skin* ; Wounds and Injuries

Although the incidence of intracranial multiple aneurysms are not low, the occurrence of multiple aneurysms more than three developing on the ipsilateral carotid artery is quite rare. We present a patient with five aneurysms on the left internal carotid artery. Four aneurysms arising from the left internal carotid artery underwent microsurgical clipping and wrapping, and remnant superior hypophyseal artery aneurysm was treated by using coil embolization. Incidence and risk factors for management of multiple aneurysms were investigated with the literature review.
Aneurysm ; Arteries ; Carotid Arteries ; Carotid Artery, Internal ; Humans ; Incidence ; Risk Factors

A 57-year-old man presented with weakness in both legs upon awakening after drinking. Magnetic resonance imaging (MRI) of the lumbar spine did not reveal any intraspinal abnormalities but MRI of the pelvis revealed lesions with abnormal intensities with heterogeneous contrast enhancement in both gluteal muscles. Serum creatine phosphokinase was markedly elevated. A diagnosis of lumbosacral plexopathy, complicating rhabdomyolysis was made. With supportive care he recovered well but mild weakness of the right ankle remained at 6 month-follow-up. Pelvic MRI is a helpful diagnostic tool in localizing rhabdomyolysis. Lumbosacral plexopathy should be included in the differential diagnosis of the such cases, presenting with sudden weakness of legs.
Ankle ; Creatine Kinase ; Diagnosis ; Diagnosis, Differential ; Drinking ; Humans ; Leg* ; Magnetic Resonance Imaging ; Middle Aged* ; Muscles ; Pelvis ; Rhabdomyolysis* ; Spine

Myxofibrosarcoma is also known as a myxoid variant of malignant fibrous histiocytoma, and this is one of the most common sarcomas in the extremities of elderly people; it is characterized by a high frequency of local recurrence. We herein report on a case of myxofibrosarcoma of the bladder. A 58-year-old man was referred to our hospital because of microscopic hematuria. Computed tomography(CT) and intravenous pyelography(IVP) showed a 12x7cm sized bladder mass in the pelvic cavity. The cystoscopic finding shows a protruding mass at the dome and posterior wall of the bladder. After exploratory laparotomy and tissue frozen biopsy were done, radical cystectomy and uretero-ileo-cutaneous anastomosis were then carried out. The diagnosis of the tumor was confirmed by histopathological examination. The myxofibrosarcoma of the bladder was completely excised, and there was no evidence of recurrence after 10 months of follow-up.
Male ; Humans ; Biopsy

The pipeline(TM) embolization device (PED) is a braided, tubular, bimetallic endoluminal implant used for occlusion of intracranial aneurysms through flow disruption along the aneurysm neck. The authors report on two cases of giant internal carotid artery aneurysm treated with the PED. In the first case, an aneurysm measuring 26.4 mm was observed at the C3-C4 portion of the left internal carotid artery in a 64-year-old woman who underwent magnetic resonance imaging (MRI) for dizziness and diplopia. In the second case, MRI showed an aneurysm measuring 25 mm at the C4-C5 portion of the right internal carotid artery in a 39-year-old woman with right ptosis and diplopia. Each giant aneurysm was treated with deployment of a PED (3.75 mm diameter/20 mm length and 4.5 mm diameter/25 mm length, respectively). Nine months later, both cases showed complete radiological occlusion of the giant intracranial aneurysm and sac shrinkage. We suggest that use of the PED can be a therapeutic option for giant intracranial aneurysms.
Adult ; Aneurysm* ; Carotid Artery, Internal* ; Diplopia ; Dizziness ; Female ; Follow-Up Studies* ; Humans ; Intracranial Aneurysm ; Magnetic Resonance Imaging ; Middle Aged ; Neck

BACKGROUND: It can be difficult to select an appropriate flap for various defects on the hand. Although defects of the hand usually must be covered with a skin flap, some defects require a flap with rich blood supply and adequate additive soft tissue volume. The authors present their experience with the anconeus muscle free flap in the reconstruction of various defects and the release of scar contractures of the hand. METHODS: Ten patients underwent reconstruction of the finger or release of the first web space using the anconeus muscle free flap from May 1998 to October 2013. Adequate bed preparations with thorough debridement or contracture release were performed. The entire anconeus muscle, located at the elbow superficially, was harvested, with the posterior recurrent interosseous artery as a pedicle. The defects were covered with a uniformly trimmed anconeus muscle free flap. Additional debulking of the flap and skin coverage using a split-thickness skin graft were performed 3 weeks after the first operation. RESULTS: The average flap size was 18.7 cm² (range, 13.5–30 cm²). All flaps survived without significant complications. Vein grafts for overcoming a short pedicle were necessary in 4 cases. CONCLUSIONS: The anconeus muscle free flap can be considered a reliable reconstructive option for small defects on the hand or contracture release of the web space, because it has relatively consistent anatomy, provides robust blood supply within the same operative field, and leads to no functional loss at the donor site.
Arteries ; Cicatrix ; Contracture ; Debridement ; Elbow ; Fingers ; Free Tissue Flaps* ; Hand* ; Humans ; Muscle, Skeletal ; Osteomyelitis ; Skin ; Tissue Donors ; Transplants ; Veins

BACKGROUND: It can be difficult to select an appropriate flap for various defects on the hand. Although defects of the hand usually must be covered with a skin flap, some defects require a flap with rich blood supply and adequate additive soft tissue volume. The authors present their experience with the anconeus muscle free flap in the reconstruction of various defects and the release of scar contractures of the hand. METHODS: Ten patients underwent reconstruction of the finger or release of the first web space using the anconeus muscle free flap from May 1998 to October 2013. Adequate bed preparations with thorough debridement or contracture release were performed. The entire anconeus muscle, located at the elbow superficially, was harvested, with the posterior recurrent interosseous artery as a pedicle. The defects were covered with a uniformly trimmed anconeus muscle free flap. Additional debulking of the flap and skin coverage using a split-thickness skin graft were performed 3 weeks after the first operation. RESULTS: The average flap size was 18.7 cm² (range, 13.5–30 cm²). All flaps survived without significant complications. Vein grafts for overcoming a short pedicle were necessary in 4 cases. CONCLUSIONS: The anconeus muscle free flap can be considered a reliable reconstructive option for small defects on the hand or contracture release of the web space, because it has relatively consistent anatomy, provides robust blood supply within the same operative field, and leads to no functional loss at the donor site.
Arteries ; Cicatrix ; Contracture ; Debridement ; Elbow ; Fingers ; Free Tissue Flaps* ; Hand* ; Humans ; Muscle, Skeletal ; Osteomyelitis ; Skin ; Tissue Donors ; Transplants ; Veins

BACKGROUND AND OBJECTIVES: Platelet-activating factor (PAF) in middle ear effusion is thought to induce hearing loss. The purpose of this study is to determine the effects of PAF placed on round window membrane (RWM) on hearing and cochlear hair cells in guinea pigs, and we also wanted to investigate the role of nitric oxide (NO) in the mechanism of PAF-induced hearing loss by comparing its immunoreactivity to iNOS between the control group and PAF application group. MATERIALS AND METHOD: Guinea pigs were divided into 2 groups: PBS, PAF. The PBS group received phosphate buffered saline (PBS) and the PAF groups received 10, 20, and 40 mug/ml of PAF soaked in gelfoam placed on the RWM. The following three tests were performed on each animal group: hearing was tested with an auditory brainstem response (ABR) test through 24 hours. At the end of 24 hours, cochlear hair cells were examined by scanning electron microscopy (SEM) and immunohistochemistry was carried out on the cochlea to test the expression of inducible nitric oxide (iNOS). RESULTS: The PAF group developed significant elevation of ABR threshold and cochlear hair cell damage in SEM compared with the PBS control group. Strong expression of iNOS on cochlea was observed in the PAF group and lighter expression was seen in PBS group. CONCLUSION: This study demonstrated that PAF placed on the RWM induced hearing loss, and cochlear hair cell damage, and strong iNOS expression in the cochlea. These findings suggest that the PAF-induced hearing loss caused by cochlear hair cell damage may have been mediated by NO. PAF-antagonists and NOS inhibitor may have future therapeutic implications in preventing sensorineural hearing loss associated with chronic otitis media.
Animals ; Cochlea ; Ear, Inner* ; Evoked Potentials, Auditory, Brain Stem ; Gelatin Sponge, Absorbable ; Guinea Pigs* ; Guinea* ; Hair ; Hearing ; Hearing Loss ; Hearing Loss, Sensorineural ; Immunohistochemistry ; Membranes ; Microscopy, Electron, Scanning ; Nitric Oxide ; Otitis Media ; Otitis Media with Effusion ; Platelet Activating Factor