1.Classifi cation of epileptic seizures and epilepsy syndromes
Neurology Asia 2013;18(s1):1-4
The efforts of ILAE for providing a standardized classifi cation and terminology of epileptic seizures
and epilepsy syndrome; the international classifi cation of epileptic seizures in 1981 and international
classifi cation of epilepsy syndromes and epilepsies in 1989, have provided outstanding achievement
in promoting epilepsy care, research, and education over the past decades. However, further attempts
of ILAE to improve and update the classifi cation systems have not been successful due to signifi cant
heterogeneities and still incomplete knowledge on the fundamental pathophysiology of epilepsies.
Despite these shortcomings, the Commission on Classifi cation and Terminology of ILAE recently
published a new proposal, “Revised Terminology and Concepts for Organization of Epileptic seizures
and Epilepsies”, which has generated lively discussions and debates throughout the international epilepsy
communities. The basic concepts for the change seem to be rational and well taken but the proposal
was not a classifi cation, which made the epilepsy communities somewhat confused and disappointed.
A new proposal of classifi cation is urgently needed to replace the overdue ILAE-classifi cation.
2.Ethical issues of using placebo in antiepileptic drugs trials in Asia
Neurology Asia 2010;15(Supplement 1):29-31
Any human trials should be designed and conducted within the ethical framework of the “Declaration of
Helsinki” stating that any new agent must be tested against standard, proven therapies when available. In
the clinical development of antiepileptic drugs, a double-blinded, placebo-controlled study is generally
considered the gold standard for establishing their clinical effi cacy. However, placing patients with
epilepsy on placebo is unethical because of negative impact of subsequent seizures resulting from
“nontherapy”. The ethical concern is relatively small in an add-on trial but becomes problematic when
a monotherapy is designed. Asia is expected to play a key role for future clinical development of new
antiepileptic drugs. Timely action and collaborations of Asian epilepsy communities for advances in
future clinical trials seems high in priority.
3.Critical Role of Multidisciplinary Team Approach in the New Field of Vascular Surgery - Endovascular Surgery.
Journal of the Korean Society for Vascular Surgery 2003;19(2):121-123
No abstract available.
4.Chronic Venous Insufficiency of Lower Extremity.
Journal of the Korean Medical Association 1998;41(6):635-646
No abstract available.
Lower Extremity*
;
Venous Insufficiency*
6.Congenital Hypothyroidism.
Journal of the Korean Pediatric Society 2003;46(Suppl 3):S363-S371
No abstract available.
Congenital Hypothyroidism*
7.Puberty: a Model for the Study of Hypothalamic Differentiation.
Journal of Korean Society of Pediatric Endocrinology 2005;10(1):1-5
No abstract available.
Adolescent
;
Humans
;
Puberty*
8.Medication Noncompliances.
Journal of the Korean Medical Association 1998;41(12):1243-1251
No abstract available.
9.Clinical effects of yeast derived recombinant methionyl growth hormone in growth hormone deficiency.
Journal of the Korean Pediatric Society 1991;34(3):334-339
No abstract available.
Growth Hormone*
;
Yeasts*
10.Clinical effects of yeast derived recombinant methionyl growth hormone in growth hormone deficiency.
Journal of the Korean Pediatric Society 1991;34(3):334-339
No abstract available.
Growth Hormone*
;
Yeasts*