No abstract available.
Korea* ; Orientia tsutsugamushi* ; Rickettsia*

No abstract available.
Pre-Eclampsia* ; Toxemia*

No abstract available.
Athletes* ; Dysmenorrhea* ; Female ; Humans

No abstract available.
Athletes* ; Female ; Humans

Extravasation of toxic chemotherapeutic 'agents cause severe skin ulceration and necrosis which often need secondary surgical intervention. Still, there were not established antidote agent in case of extravasation with mitomycin-c. Dimethyl sulfoxide is known as an effective chemical scavenger of toxic hydroxyl free radical and sodium thiosulfate also was demonstrated significant protector from mitomycin-c induced ulceration by a few experimental studies. Author investigated necrotic area of mitomycin-c injected site and compare to the effectiveness of topical treatment with dimethyl sulfoxide and intradermal injection of sodium thiosulfate according to starting times, forty five mice were divided into 3 groups. Control group(n=5) had no treatment after subcutaneous injection of mitomycin-c. Experimental group I and 11 were 20 mice treated dimethyl sulfoxide and sodium.
Animals ; Dimethyl Sulfoxide ; Injections, Intradermal ; Injections, Subcutaneous ; Mice ; Mitomycin* ; Necrosis* ; Skin Ulcer ; Sodium* ; Ulcer

No abstract available.
Free Tissue Flaps*

No abstract available.
Porphyria, Acute Intermittent* ; Pregnancy*

The authors investigated diurnal change of urinary pH in control group and urine alkalizing group. The control group composed of normal group and hydration group (water 2000 cc/day). The urine alkalizing agent group composed of sodium bicarbonate group (4gm/day, 6mg./day, 8gm/day and 12gm./day) and citrate agent groups (Eisenberg`s solution; 60cc/day and CG-120 or Uralyt-U;4gm./day) in 15 normal healthy adult male. The results were summarized as follows; 1. In normal control group and hydration group, diurnal urinary pH were 5.89+0.47 and 6.00 + 0.44 respectively, There was no significant difference between normal control group and hydration group (p<0.05). 2. In urine alkalizing agent foup, diurnal urinary pH of sodium bicarbicar-bonate groups (4gm./day, 6gm./day, 8gm./day and 12gm./day) were 6.26+0.51, 6.64+0.41, 6.74+0.53 and 7. 15+0.64 respectively, and diurnal urinary pH of citrate agent foups (Eisenberg`s solution and CG-120) were 7.04+0.78 and 6.48+0.60 respectively. The urinary pH was increased about 0.1 every 1gm./day addition of sodium bicarbonate. For maintenance of urinary pH between 6.2-7.0 administration 4-8gm./day of sodium bicarbonate was favorable. It was 5 times as much as CG-120 (4gm./day) in amount that Eisenberg`s solution contains 19.12gm of citrate in diurnal administration volume (60cc/day). So the augment effect of urinary pH of CG-120 was significantly great and its side effect was relatively less.
Adult ; Citric Acid ; Humans ; Hydrogen-Ion Concentration ; Male ; Sodium ; Sodium Bicarbonate

The authors obtained the following results through comparative investigation between experiences from authors clinical study of ureterolithotomy by posterior vertical incision devised by Gil-Vernet and Yoon`s clinical study of ureterolithotomy by posterior vertical incision and his lumbar incision. 1. Operation time was average 62 min. and blood loss was average about 50cc. So operation time and blood loss were similar to Yoon`s result but more or less reduced as compared with lumbar incision. 2. Postoperative urine leakage and ambulation time were 1 day and 2 day that were more or less reduced as compared with Yoon`s result. 3. Ipsilateral lower abdominal wall protrusion was noted postoperatively. We think, this is from subcostal nerve injury. 4. Postoperatively sensation change on subcostal nerve, ilohypogastric nerve and ilioinguinal nerve innervation sites were noted in half of all, but disappeared in several weeks. Considering above results, while posterior vertical incision has merits such as minimal operative invasion and early postoperative ambulation time, but it often notes inevitable nerve damage. So, we think better results would be gained by careful attention to nerve and vascular distribution.
Abdominal Wall ; Sensation ; Walking

BACKGROUND: Esmolol has been applied to lower myocardial oxygen consumption and creates a quieter operative field by reducing systemic blood pressure and heart rate but can cause a certain amount of hemodynamic instability during minimally invasive direct vision coronary artery bypass graft (MIDCAB). The aim of this study was to compare the hemodynamic differences between two methods; inducing hypotension and bradycardia between esmolol infusion alone, and concomitant use of neostigmine during MIDCAB anesthesia. METHODS: Twenty MIDCAB patients were randomly allocated into two groups, group E (n = 10) receiving esmolol 0.3 mg/kg/min, group EN (n = 10) receiving esmolol 0.2 mg/kg/min and neostigmine 1.0 mg for induced hypotension and bradycardia during coronary anastomosis. The hemodynamic parameters were evaluated 10 minutes after induction of anesthesia (T1), 10 minutes after beginning of operation (T2), 5 minutes before the end of anastomosis (T3) and 10 minutes after the end of anastomosis (T4). Data were analyzed by ANOVA test for intragroup comparisons, and by T-test for intergroup comparisons with significance set at a P value of < 0.05. RESULTS: Heart rate significantly decreased at T3 in both groups and more in group EN. Systolic blood pressure decreased at T3 in both groups and there were no group differences but more episodes of extreme hypotension in group E. The cardiac index significantly decreased at T3 in both groups and more in group E. There was a small but significant increase in pulmonary capillary wedge pressure at T3 and T4 in group E and no change of central venous pressure in both groups. CONCLUSION: Concomitant use of neostigmine during esmolol infusion produces more reliable induced hypotension and bradycardia than esmolol infusion alone for MIDCAB anesthesia in terms of prevention of myocardial ischemia and easiness of anastomosis technique.
Anesthesia* ; Blood Pressure ; Bradycardia* ; Central Venous Pressure ; Coronary Artery Bypass ; Heart Rate ; Hemodynamics ; Humans ; Hypotension* ; Myocardial Ischemia ; Neostigmine* ; Oxygen Consumption ; Pulmonary Wedge Pressure ; Transplants