The clinical and mycological investigation was made with 68 cases of tinea corporis who had visited the Dermatologic Clinic of N.M.C. from Nov. 1985 to Oct. 1988. The results were as follows : 1. The ratio of male to female was 1.1: 1, and tinea corporis was most preva lent in the twenties. 2. 25 cases (36.8%) had a history of contact with infected animals or soil. 3. 75% of cases had less than 2 lesions. The exposed area was more frequently affected, and the face being the most frequent site. 4, Concurrent infection of tinea corporis with other types of dermatophytosis were noted in 33 cases (48.8%), and the most common was tinea pedis. 5. From the 68 cases, 49 organisms composed of 4 species were isolated, which were T. rubrum (32 cases), M. Canis (11 cases), T. mentagrophytes (5 cases) and M. gypseem (1 case). 6. Of the clinical variants of tinea corporis, the annular type was most comm only noted. No species specificity was noted in annular type, but T. rubrum was the major causative organism of eczematous and plaque type, and M. canis was the only isolated organism in herpetiform type. 7. As compared with other dermatophytes, M. canis was more commonly isolated from the smaller lesion.
Animals ; Arthrodermataceae ; Female ; Humans ; Male ; Soil ; Species Specificity ; Tinea Pedis ; Tinea*

We report a case of hereditary trichilemmal cyst with proliferating trichilemmal tumor in a 64-year-oid man, who has generalized 157, variable sized firm cutaneous nodules for 40 years. The cystic nodules are chiefly located on the scalp and trunk which showed characteristic histopathologieal findings of trichilemmal cyst and proliferating trichilemmal tumors. His son also has multiple trichilemmal cysts and his mother seems to have had clinically similar lesions. The patient and his son were treated with surgical excision and therapeutic trial of oral isotretinoin for 2 months. Isotretionoin was ineffective in the patient, but the lesions of his son were decreased in size.
Humans ; Isotretinoin ; Mothers ; Scalp

We report, a 1-day-old male with congenital cutaneous candidiasis who had generalized erythematous papules and pustules on the whole body including palms and soles from birth. At 5th month of pregnancy, his mother had a history of vaginal candidiasis for a month KOH mount of pus from pustules of several different sites showed budding spores and pseudohrphae and fungus culture revealed the growth of Candida albicans We believe this to he the first documented case of congenital cutaneous candidiasis in Korean literature.
Candida albicans ; Candidiasis ; Candidiasis, Cutaneous* ; Fungi ; Humans ; Male ; Mothers ; Parturition ; Pregnancy ; Spores ; Suppuration

We describe a case of typical cytophagic histiocytic panniculitis occuring in 10-year-old male. He had recurrent subcutaneous nodules, fever, pancytopenia and abnormal liver function tests since 5 months of his age, and recently showed hemorrhagic diathesis. The histologic picture showed lobular histiocytic panniculitis with "bean bag" cytophagic cells.
Child ; Fever ; Hemorrhagic Disorders ; Humans ; Liver Function Tests ; Male ; Pancytopenia ; Panniculitis*

No abstract available.
Hemorrhagic Fever with Renal Syndrome* ; Humans ; Proteinuria*

No abstract available.
Animals ; Captopril* ; Cisplatin* ; Nifedipine* ; Rats*

No abstract available.
Animals ; Cricetinae* ; Cryopreservation* ; Oocytes*

No abstract available.
Gonadotropins* ; Oocytes*

No abstract available.
Humans ; Hypophosphatemia*

BACKGROUND: Mechanisms of secondary injury(post-ischemic injury) in the central nervous system have recently reported in a vast of amount of experiments. Among many factors which give rise to post-ischemic neuronal damage, glial deterioration probably mediated by calcium paradox, could be another of the aggravating deleterious factors to the already ischemic neurophil. METHODS: here we have designed experiment to investigate calcium paradox in astroglial cell line, human astrocytoma U1242MG. Intracellular calcium alterations in experimental cells were monitored by using calcium indicating dye fura-2 and epifluorescent photometry system. RESULTS: Intracellular free calcium changes during reperfusion phase after exposure to low calcium led to a prompt increase in intracelluar calcium level after 10 and 30 minutes. The way of calcium entry during the reperfusion phase was mediated by the reverse mode of NA+/Ca2+ exchanger. Cells that had a reduction of reperfusate calcium to 10uM increased cell viability. Also we observed an inverse relationship between major enzymatic activity in the astrocytoma cells(i.e., gultamine synthetase activity) and the duration of reperfusion in the the same protocols. CONCLUSIONS: A relatively small amount of intracellular clcium increase by the reverse mode of Na+/Ca2+ exchanger during the reperfusion period is related to a limitation of enzyme activity and viability 24hours later.
Astrocytoma ; Brain ; Calcium ; Cell Line ; Cell Survival ; Central Nervous System ; Fura-2 ; Humans ; Ions ; Ligases ; Neuroglia* ; Neurons ; Photometry ; Reperfusion Injury* ; Reperfusion*