The author investigated the effect of Mg++, Ca++, Na+ and K+ on the ATPase activity of mitochondrial fraction isolated from bovine extraocular muscles and ciliary processes and obtained the following results: 1. The mitochondrial fraction isolated from bovine extrocoular muscle and ciliary process appeared to possess the Na+ & K+ activated ATPase in the presence of Mg++, and on the contrary, in the absence of Mg++, the ATPase was not activated by K+, Na+ and Ca++. 2. The ATPase activity was enhanced with the increase of protein concentration in fractions from both, the bovine extraocular muscle and the ciliary process. 3. The ATPase in those fractions was potently activated under the condition of that the sample was modulated at 10 mM of K+ and 100 mM of Na+, respectively. 4. The K+- and Na+-activated ATPase in the presence of Mg++ was stimulated to enhance its activity by the addition of Ca++ up to 5 micro M, thoughby the higher concentration of Ca++ up to 10 micro M, its activity did not correspondingly increase.
Adenosine Triphosphatases* ; Muscles

The author investigated the effect of adrenergic and adrenergic blocking agents on the phosphorylase activity of bovine extraocular muscle in vitro and obtained the following results: 1. The phosphorylase a activity of bovine extraocular muscle was revealed 53.6% in vitro. 2. The phosphorylase a activity of bovine extraocular muscle was slightly enhanced by the adrenergic agents such as epinephrine, norepinephrine and isoproterenol. 3. The phosphorylase a activity of bovine extraocular muscle was not affected by the adrenergic areceptor blocking agent, phenoxybenzamine but slightly inhibited by the adrenergic beta-receptor blocking agent, propranolol. 4. The phosphorylase a activity of bovine extraocular muscle previously treated with the adrenergic agents was blocked by a sole administration of propranolol or combined administrations of propranolol and phenoxybenzamine but not blocked by phenoxybenzamine alene.
Adrenergic Agents ; Adrenergic Antagonists* ; Epinephrine ; Isoproterenol ; Muscles* ; Norepinephrine ; Phenoxybenzamine ; Phosphorylase a ; Propranolol

The authors analysed 340 cases of the ocular injuries among 7633 out and in-patients who visited to the clinic of P.N.U. hospital during 5 years, from Jan. 1964 to Dec. 1968. Followings were discussed. 1. We found that 4.6% of all cases attending our eyes clinic was victims of ocular injuries. 2. The sex incidence showed that 78.9% of such ocular injuries occured in male and 21.1% in female. 3. The incidence was prevalent in young adult 21-30 years of age, and their large number of cases were injured from blowing and industrial accidents, while in children under 10 years of age sharp-pointed toys were more frequent causes. 4. The subconjunctival hemorrhage was the most frequent disturbance of ocular injuries and then came traumatic cataract and corneal foreign bodies in that order. 5. The prognosis of ocular injuries was generally poor, especially, poor, especially in the perforating and penetrating wound of the whether the foreign body was retained or not.
Accidents, Occupational ; Cataract ; Child ; Female ; Foreign Bodies ; Hemorrhage ; Humans ; Incidence ; Male ; Play and Playthings ; Prognosis ; Wounds, Penetrating ; Young Adult

A method of charting and scoring the optic disc and cupping from fundus color photographs is presented. The imase that the color slides were projected on the graphic sheet was traced and calculated C/D ratio as horizontal diameter and mensuration of division by measure. The result showed statiscal significancy in calculation of the C/D ratio as mensuration of division in cases which the cupping showed irregular form.

The orbitll sparganosis is an extremely rare disease which clinical signes were similar to orbital-cellulitia. Authors reported a case of sparganosis which a 59 years old Korean man complained swellina of lid, chemosis and dull ocular pain in the right eye for 5 months. On eye examination, the visual acuity was 0.5 in the right eye and 0.8 in the left which was incorrectable because of bilateral senile cataract. The left eye had no other anomalities. The right eye was markedly chemotic and restricted ocular motility in the 6 cardinal directions but no exophthalmos. There was a soft elevated and mobile nodule subconjunctivally on the upper portion of the globe and the other nodule was palpated along lower orbital margin. Roentgenologic findings showed diffuse increased radiopaque density but no bony changes in the orbit. Chest and skull x-ray were normal. In the laboratory findings, eosinophilia showed in CBC, hookworm, trichuris T., and T. orientalis in stool examination and positive skin test in Paragonimus westermani and Clonorchis sinensis. On the 3rd, Sep., 1971, we found 4 spargana on surgical exploration of which sizes were approximately 8.5, 9.5, 5.0, and 3.6 cm. in length. A sparganum in upper portion freely stirred sluggishIy in the subconjunctiva but the other 3 in the lower orbital portion were found in the seperated long cysts. The cystic tissue showed nonspecific chronic inflammatory reaction in pathological examination. The infected source was suggested to a history of having taken raw flesh of snake about 30 years ago. Orbital signs were much regressed 15 days later after operation.
Ancylostomatoidea ; Cataract ; Clonorchis sinensis ; Eosinophilia ; Exophthalmos ; Humans ; Middle Aged ; Orbit ; Paragonimus westermani ; Rare Diseases ; Skin Tests ; Skull ; Snakes ; Sparganosis* ; Sparganum ; Thorax ; Trichuris ; Visual Acuity

The orbitll sparganosis is an extremely rare disease which clinical signes were similar to orbital-cellulitia. Authors reported a case of sparganosis which a 59 years old Korean man complained swellina of lid, chemosis and dull ocular pain in the right eye for 5 months. On eye examination, the visual acuity was 0.5 in the right eye and 0.8 in the left which was incorrectable because of bilateral senile cataract. The left eye had no other anomalities. The right eye was markedly chemotic and restricted ocular motility in the 6 cardinal directions but no exophthalmos. There was a soft elevated and mobile nodule subconjunctivally on the upper portion of the globe and the other nodule was palpated along lower orbital margin. Roentgenologic findings showed diffuse increased radiopaque density but no bony changes in the orbit. Chest and skull x-ray were normal. In the laboratory findings, eosinophilia showed in CBC, hookworm, trichuris T., and T. orientalis in stool examination and positive skin test in Paragonimus westermani and Clonorchis sinensis. On the 3rd, Sep., 1971, we found 4 spargana on surgical exploration of which sizes were approximately 8.5, 9.5, 5.0, and 3.6 cm. in length. A sparganum in upper portion freely stirred sluggishIy in the subconjunctiva but the other 3 in the lower orbital portion were found in the seperated long cysts. The cystic tissue showed nonspecific chronic inflammatory reaction in pathological examination. The infected source was suggested to a history of having taken raw flesh of snake about 30 years ago. Orbital signs were much regressed 15 days later after operation.
Ancylostomatoidea ; Cataract ; Clonorchis sinensis ; Eosinophilia ; Exophthalmos ; Humans ; Middle Aged ; Orbit ; Paragonimus westermani ; Rare Diseases ; Skin Tests ; Skull ; Snakes ; Sparganosis* ; Sparganum ; Thorax ; Trichuris ; Visual Acuity

All physicans regard the fundus as an important guide to prognosis in the systemic disease which permits the retinal changes, especially hypertension. There are fallacies in the ophthalmoscopic examination of as essing arteriolar calibre by the arteriovenous ratio. The selection of comparable vessels by ophthalmoscopy for the estimation of the arteriovenous ratioshould be fully appreciated, and no other reference base is available unless measurments are made on retinal photographs or by means of an ophthalmoscope fitted with a special graticule. Studies were made by a random selection of 30 normal persons (60 fundi) in 2nd decades. This series of fundus color photographs incorporated a field extending to 3-5 disc diameters from the disc margin. This paper is a series on the retinal vessels which was concerned with the arteriovenous comparable pairing and its ratio. The results were: 1. Total comparable pairs ware 142 pairs in the 60 fundi. 2. In the 60 fundi comparable pairs were found in 50, and in 118 out of 240 quadrants(48 percent). 3. Comparable pairs were found more frequently in the temporal half of fundi. 4. The mean A/V ratio was 0.703.
Humans ; Hypertension ; Ophthalmoscopes ; Ophthalmoscopy ; Prognosis ; Retinal Vessels ; Retinaldehyde*

All physicans regard the fundus as an important guide to prognosis in the systemic disease which permits the retinal changes, especially hypertension. There are fallacies in the ophthalmoscopic examination of as essing arteriolar calibre by the arteriovenous ratio. The selection of comparable vessels by ophthalmoscopy for the estimation of the arteriovenous ratioshould be fully appreciated, and no other reference base is available unless measurments are made on retinal photographs or by means of an ophthalmoscope fitted with a special graticule. Studies were made by a random selection of 30 normal persons (60 fundi) in 2nd decades. This series of fundus color photographs incorporated a field extending to 3-5 disc diameters from the disc margin. This paper is a series on the retinal vessels which was concerned with the arteriovenous comparable pairing and its ratio. The results were: 1. Total comparable pairs ware 142 pairs in the 60 fundi. 2. In the 60 fundi comparable pairs were found in 50, and in 118 out of 240 quadrants(48 percent). 3. Comparable pairs were found more frequently in the temporal half of fundi. 4. The mean A/V ratio was 0.703.
Humans ; Hypertension ; Ophthalmoscopes ; Ophthalmoscopy ; Prognosis ; Retinal Vessels ; Retinaldehyde*

The authors presented a case of von Hippel-Lindau's disease. The patient was a 33-year-old man who visited to our hospital with visual disturbance on the right eye for a month and blind in the left eye for 10 years on the 4th May, 1973. On the eye examination, the left eye revealed ocular hypertension, deep chamber, and vitreous opacity which interfered with the visuality of the fundus. The right eye was normotensive and 0.1 incorrectable in visual acuity. The fundus revealed two angioma associated with large feeding vessels, scattered hemorrhages, and massive exudates along the engorged and tortuous vessels at the temporal retina. On general physical examination, no neurological signs were found, but multiple hard corn sized masses were palpated on the both sides of epididymal head. The masses were confirmed as epididymal cyst on microscopic examination. The x-ray findings were pulmonary tuberculosis far advanced on chest, an extrinsic pressure indentation in the floor of bladder on I.V.P., and abnormal intracranial vascularity, on right carotid angiogram. The blood chemistry showed an abnormal increase of amylase and lipase titers.
Adult ; Amylases ; Chemistry ; Exudates and Transudates ; Head ; Hemangioma ; Hemorrhage ; Humans ; Lipase ; Ocular Hypertension ; Physical Examination ; Retina ; Spermatocele ; Thorax ; Tuberculosis, Pulmonary ; Urinary Bladder ; Visual Acuity ; Zea mays

The authors presented a case of Goldenhar's Syndrome which was shown the following findings, such as epibulbar dermoid, bilateral colobomas of upper eye lids, pretragal blind fistulas, preauricular appendages, skin tags, lacrimal fistula, persistant pupillary membrane, myopia and alopecia atropicans with bulae.
Alopecia ; Coloboma ; Dermoid Cyst ; Fistula ; Membranes ; Myopia ; Skin