No abstract available.
Adenocarcinoma* ; Estrogens*

No abstract available.
Arnold-Chiari Malformation*

Tetrodotoxin (TTX) cause neurologic dysfunction by blocking the voltage-gated sodium channels located in all of the peripheral nerves and muscles. We experienced two patients presenting with generalized motor weakness after ingestion of pufferfish. The nerve conduction study showed diffuse slowing of motor and sensory nerve conduction velocity, prolonged motor terminal latency and decreased sensory nerve action potentials without temporal dispersion or conduction block. Abnormal findings of nerve conduction study improved rapidly without any deterioration. Clinical symptoms and signs ameliorated in accordance with findings of nerve conduction study without any neurologic sequelae. These imply that tetrodotoxication is reversible and functional neurologic disorder. We suggest that nerve conduction studies can be available in serial monitoring of tetrodotoxication as an objective means.
Action Potentials ; Eating ; Humans ; Muscles ; Nervous System Diseases ; Neural Conduction ; Neurologic Manifestations ; Peripheral Nerves* ; Tetraodontiformes ; Tetrodotoxin ; Voltage-Gated Sodium Channels

No abstract available.
Lymph Nodes* ; Rectal Neoplasms* ; Rectum*

No abstract available.
Carcinogenesis* ; Colorectal Neoplasms*

Clinical observation was performed on the 71 hips of 52 patients which were replaced by total hip arthroplasty, who were treated at department of Orthopedic Surgery, College of Medicine, Kyungpook National University, from 1980 to 1985. The follow up period of each case varied from 2 to 7 years. The results obtained were as follows : 1. The peak age incidence ranged from 40 to 49 years, which was comprised 55.8%(29 patients) of total cases. Male was predominant(46 patients of total cases). 2. The cause of hip diseases were ; 49 cases of idiopathic avascular necrosis, which comprised highest incidence, 15 posttraumatic avascular necrosis, 4 osteoarthritis, 3 old pyogenic hip. 3. The lesion site were ; 23 right side, 10 left side and 19 both sides. All cases were Muller type which performed the Watson-Jones approach. 4. Seversl complications were developed; 1 subtrochanteric spiral fracture, 1 perforation of acetabulum, 1 perforation of femur shaft, 1 perforation of lesser trochanter of femur, 1 nerve palsy during the operation, post-operative superficial wound infection in 1 case, deep seated infection in 1 case, and wire breakage in 6 cases. 5. Preoperative and post-operstive functional evaluation by the Harris method was done ; 1) Average improvement was 49 points from 38.2 to 87.2 points. 2) Relief of pain was the most prominent effect of the total replacement surgery.
Acetabulum ; Arthroplasty, Replacement, Hip ; Femur ; Follow-Up Studies ; Gyeongsangbuk-do ; Hip ; Humans ; Incidence ; Male ; Methods ; Necrosis ; Orthopedics ; Osteoarthritis ; Paralysis ; Wound Infection

The subtrochanteric fracture of the femur is often comminuted because the subtrochanteric area is composed mainly of cortical bone and high compression force biomechanically and its proximal fragment is severely displaced by adjacent strong muscles. Therefore, it is difficult to maintain accurate reduction and rigid fixation and delayed or nonunion, limb shortening, varus deformity, metal failure, and many other problems can be encountered. Although various devices of internal fixation have been developed to solve these problems, we found many problems to select the fixation device in different fracture type properly. We studied 40 subtrochanteric fractures treated with various devices at our hospital from 1981 to Feb. 1987. The results were obtained as follows: 1. Male (28 patients, 70%) was predominant. The majority of patients (representing 55%) were between 31 and 60 years of age. While 10 of 12 female patients were after 50 years of age. 2. In 36 of 40 patients, the fracture resulted from high energy trauma, traffic accident or fall from height. 3. Pelvic bone fracture (4 cases)and head trauma (3 cases) were the most common associated injuries. 4. Fielding's type II(19 cases) fracture and Seinsheimer's type IV (10 cases) & V (9 cases) fractures were most common. 5. Of the 40 cases, 38(95%) were treated by open reduction and internal fixation. Of fixation devices, a Jewett nail was most commonly used in 23 cases (60.5%) 6. The average time from operation to partial weight bearing was 12.2 weeks. 7. The mean duration of bony union was 25 weeks. And more longer period was needed in union as fractures goes distally 8. Of the 40 cases, 4 (10%) complications occured, those are : metal failure and fixation screw loosening (2 cases), infection (1 case), varus deformity (1 case). 9. From these series, these fractures should be treated as rigid internal fixation and Jewett nail or many other devices such as compression hip screw, condylar plate, or Judet plate could be applied successfully for the rigid fixation of subtrochanteric fractures of the femur according to the fracture displacement and stability.
Accidents, Traffic ; Clinical Study ; Congenital Abnormalities ; Craniocerebral Trauma ; Extremities ; Female ; Femur ; Hip ; Hip Fractures ; Humans ; Male ; Muscles ; Pelvic Bones ; Weight-Bearing

No abstract available.
Adenosine Deaminase* ; Adenosine* ; Bronchoalveolar Lavage Fluid* ; Bronchoalveolar Lavage* ; Humans ; Tuberculosis, Pulmonary*

We investigated the association between the oxidative stress and the concentration of heavy metals in blood among welders. The study subjects were male manual CO2 welders(N=127) exposed to several heavy metals. The age distribution was from 20 to 63 (GM=33.7) and the geometric mean(GM) of work duration was 4.2 years. We analyze the level of blood lead, cadmium, managese and chromium which was related with the oxidative stress in the animal studies. Blood selenuim, plasma malondialdehyde (MDA), plasma alpha-tocopheol and orythrocyte superoxide dismutase (SOD) were analyzed as biological markers of the oxidative stress. The results of univariate analysis showed that the plasma MDA was significantly correlated with D-tocopherol (r=0.327) and blood selenium (r=0.313) concentration. But we could not find out any relationship between the erythrocyte SOD activities and those metal concentrations. Neither smoking nor alcohol consumption was related to the level of heavy metals and the oxidative stress biomarkers. As the results of multiple regression analysis with stepwise selection method, 1) the change of MDA level were dependant with the level of alpha-tocopherol and blood selenium concentration (R2=19.7), 2) the plasma alpha-tocopherol level was dependant with MDA and blood chromium concentration (R2=15.6), 3) in case of erythrocyte SOD activity, only the duration of work was significantly selected.
Age Distribution ; Alcohol Drinking ; alpha-Tocopherol* ; Animals ; Biological Markers ; Cadmium ; Chromium ; Erythrocytes* ; Humans ; Male ; Malondialdehyde* ; Metals, Heavy* ; Oxidative Stress ; Plasma* ; Selenium ; Smoke ; Smoking ; Superoxide Dismutase* ; Superoxides*

Systemic lupus erythematosus(SLE) is a systemic disease of unknown etiology. Its main pathology is vasculitis and serositis, due to deposition of the immune complex or antibodies. Most findings are nonspecific ; abdominal manifestations include enteritis, hepatomegaly, pancreatic enlargement, serositis, lymphadenopathy, splenomegaly,nephritis, interstitial cystitis, and thrombophlebitis. We described radiologic findings of various organinvolvement of SLE; digestive system, serosa, reticuloendothelial system, urinary system, and venous system.Diagnosis of SLE was done according to the criteria of American Rheumatism Association. Understanding of thevariable imaging findings in SLE may be helpful for the early detection of abdominal involvement andcomplications.
Antibodies ; Antigen-Antibody Complex ; Cystitis, Interstitial ; Digestive System ; Enteritis ; Hepatomegaly ; Lupus Erythematosus, Systemic* ; Lymphatic Diseases ; Mononuclear Phagocyte System ; Pathology ; Rheumatic Diseases ; Serositis ; Serous Membrane ; Thrombophlebitis ; Vasculitis