No abstract available.
Hippocampus* ; Humans*

PURPOSE: Prostaglandins(PGs) are known to produce a remarkably broad spectrum of effects that embraces practically every biological function, and has a particular physiological role in the central nervous system. Significant increases of PGs levels are seen in certain diseases, such as febrile infection, stroke, schizophrenia, and epilepsy. Prostaglandin is also increased in a response to rising body temperature, and prostaglandin E-2(PGE-2) in lumber cerebrospinal fluid is also increased in febrile convulsion. Intracerebroventricular injection of PGE produces a rise in body temperature and also antagonizes convulsions induced by pentylenetetrazole, penicillin, electric shock. Therefore we studied PGE-2 levels in cerebrospinal fluid of afebrile children, children with febrile convulsion, and febrile children without convulsion. METHODS: The subjects comprised 57 cases with febrile convulsion, 24 cases of afebrile diseases and 9 febrile children without convulsion. All patients were undergoing lumbar puncture and PGE-2 levels in CSF were determined by highly specific radio-immunoassay(Prostaglandin E2 [125I] assay system, Biotra Assays, Amersham Inc.). RESULTS: 1) The CSF PGE-2 levels were significantly higher in children with febrile convulsion(147.3+/-79.3pg/ml) than those in febrile children without convulsion(72.4+/-75.4pg/ml) and afebrile children(19.2+/-28.4pg/ml)(p<0.05). 2) There were no statistical significances of the CSF PGE-2 levels between age and fever in both groups. 3) The CSF PGE-2 levels within 4 hours(176.5+/-65.7pg/m1) after convulsions were significantly higher than those 4 hours after convulsion(93.3+/-74.9pg/ml). CONCLUSION: The CSF PGE-2 levels were significantly higher in children with febrile convulsion than those in febrile children without convulsion and those in afebrile child ran. The CSF PGE-2 levels within 4 hours after convulsion were significantly higher than those 4 hours after convulsion.
Body Temperature ; Central Nervous System ; Cerebrospinal Fluid* ; Child* ; Epilepsy ; Fever ; Humans ; Penicillins ; Pentylenetetrazole ; Prostaglandins E ; Prostaglandins I ; Schizophrenia ; Seizures ; Seizures, Febrile* ; Shock ; Spinal Puncture ; Stroke

PURPOSE: We evaluated the role of conventional CT for preoperative staging of gastric carcinoma. MATERIALS AND METHODS: Conventional CT was prospectively performed in 95 patients with gastric adenocarcinoma proved by means of endoscopic biopsy, and findings were compared with those of surgery or pathology. RESULTS: In the evaluation of pancreatic invasion of the primary tumor, the sensitivity, specificity, and diagnostic accuracy of CT were 71%(5/7), 95%(84/88), and 94%(89/95), respectively. CT depicted transverse mesocolon invasion in only one of the 4 cases(25%). In the evaluation of lymph node metastasis, the sensitivity, specificity, and diagnostic accuracy were 33%(24/72), 99%(867/878), and 94%(891/950), respectively. In lymph node staging, 49 patients(52%) were correctly staged, 39(41%) were understaged, and 7(7%) were overstaged with CT. CT failed to demdnstrate peritoneal carcinomatosis in all 10 patients. CONCLUSION: The role of conventional CT in the preoperative evaluation of gastric adenocarcinoma is limited due to poor sensitivity despite of good specificity and accuracy.
Adenocarcinoma ; Biopsy ; Carcinoma ; Humans ; Lymph Nodes ; Mesocolon ; Neoplasm Metastasis ; Pathology ; Prospective Studies* ; Sensitivity and Specificity

No abstract available.
Child* ; Epilepsy* ; Humans

PURPOSE: To evaluate the relative value of arterial, portal venous and delayed phase images of spiral CT in the detection of metastatic tumor of the liver. MATERIALS AND METHODS: Forty-three metastatic tumors in twelve patients were underwent tri-phasic spiral CT examination with injection of 120 ml ionic contrast material (36 g of iodine) at the rate of 3 ml/sec. Arterial, portal venous and delayed phase CT images were obtained 35, 65, and 360 seconds after the start of contrast injection, respectively. RESULTS: Arterial phase images detected 35(81%), portal venous phase images 43(100%), and delayed phase images 34(79%) lesions, respectively(p<0.05). All masses larger than 2cm(n=23) were detected in all three phases, whereas 60%, 100%, 55%of the masses smaller than 2cm(n=20) were detected in arterial, portal venous and delayed phase CT, respectively. The best contrast between masses and the hepatic parenchyma was in portal venous phase followed by arterial and delayed phase(p<0.01). In two hypervascular masses, the contrast was better in arterial phase. CONCLUSION: Portal venous phase of spiral CT is optimal in the detection of metastatic tumor of the liver. Arterial phase may be helpful for the detection of hypervascular metastasis. Delayed phase should be used restrictively.
Humans ; Liver* ; Neoplasm Metastasis ; Tomography, Spiral Computed*

Calcaneus is the largest tarsal bone and serves weight bearing of the body. The calcaneus has a pattern of cancellous bone enclosed with a very thin cortical shell. It is difficult to reduce the bony fragments accurately when there are comminution and displacement on the calcaneal fractures. Retrospective study was carried out of 18 patients(21 feet) of calcaneus fractures after axial fixation in Soonchunhyang University Hospital from July, 1982 to July, 1988. Minimum follow up period was 8 months(average 2 years 6 months). The clinical analysis of them are reported with a review of the literature and the results are follows:l. According to the Rowe's unit system, the results of treatment were excellent or good in 9 cases of 13 tongue types and 5 cases of 8 joint depression types. 2. The results were satisfactory in the calcaneal fractures of well reestablished Bohler angle to 21-30 degrees. 3. The results were excellent or good in 5 cases operated within post-trauma 1 week and in 9 cases operated from 1 week to 2 weeks. 4. The results were poor in the 2 joint depression type with severe comminution. And subtalar joint fusion was performed on the previous 2 cases. Then pain on the lateral malleolar area was subsided.
Calcaneus ; Depression ; Follow-Up Studies ; Joints ; Retrospective Studies ; Subtalar Joint ; Tarsal Bones ; Tongue ; Weight-Bearing

Malignant neuroepithelioma is a rare neoplasm arising within the peripheral nervous system and usually occurs in the lower extremities. It may involve patients in any age group and have no gender predisposition. In adolescents and adults the tumor must be distinguished from other malignant round-cell tumors. The poor prognosis and the need for aggressive, combined surgical and chemotherapeutic modalities in treating this tumor necessitate a prompt and accurate diagnosis. Authors have experienced a case of malignant neuroepithelioma developed in left sciatic nerve. The diagnosis was confirmed by CT scan, M.R.I., light and electron microscopic findings.
Adolescent ; Adult ; Diagnosis ; Humans ; Lower Extremity ; Neuroectodermal Tumors, Primitive, Peripheral ; Peripheral Nervous System ; Prognosis ; Sciatic Nerve ; Tomography, X-Ray Computed

Mirizzi syndrom is a rare disorder characterized by obstruction of common hepatic duct due to impacted gallbladder neck or dystic duct stone and is an uncommon cause of obstructive jaundice. Authors experienced one case of Mirizzi syndrome mimicked lobulated intraductal tumor.
Gallbladder ; Hepatic Duct, Common ; Jaundice, Obstructive ; Mirizzi Syndrome ; Neck

Recently data about performances in radiology department tend to increase rapidly and appropriate use of computer system is needed to monitor variuos jobs including scheduling of the patient, reporting of radiologic examination and film library management. The authors describe experiences in computerizing several jobs of radiology departement using Aplle II personal computer during last uear, and our experiences suggest that with appropriate soft ware and peripheral devices, personal computer can handle relatively large amount of informations about a certain functions in radiology department. The authors also put emphasis on the point that meticulous characterization and cocumentation of data is mandatory for effective use of computer system and should be done by radiologist who use or want to use computer system.
Computer Systems ; Humans ; Microcomputers

No abstract available.
Talus*