No abstract available.
Publications*

A case oof erythema elevatum diutinum in 30-year old male was described. Reviewing literatures, this disease is very rare and is the first case to be reported in Korea. There were persistant elevated hard brownish red nodulo-infiltrated plaques which were symmetrically distributed especia]ly over the shins, elbows, knees, ear lobes, buttocks, and dorsal surfaces of the hands, feet, fingers, and toes, accompanied by occasional mild itching. These skin eruption were started from the erythematous papulo-vesicular macules which developed on the left shin and wrist about 7 years previously. He has also had a long-standing encapsulated pleural effusion with marked pleural thickening in left lower chest which was diagnosed 3 years ago. The serum IgG was noted to be increased. Histological examination of skin lesions revea]ed leucocytoclastic angiitis and sevrer perivascular fibrosis in older lesions.
Adult ; Buttocks ; Ear ; Elbow ; Erythema* ; Fibrosis ; Fingers ; Foot ; Hand ; Humans ; Immunoglobulin G ; Knee ; Korea ; Male ; Pleural Effusion ; Pruritus ; Skin ; Thorax ; Toes ; Vasculitis ; Wrist

A clinical and histological study of typical sebaceous epithelioma (basal cell epitheioma with sebaceous differentiation) developed secondarily in lesions of nevus sebaceus of Jadassohn is presented. The patient was 42 years old male. The sebaceous epithelioma tends to have about the same clinical characteristics as undifferentiated basal cell epithelioma but it is more often a yellow color. Sebaceous epitheliova may arise from nevus sebaceus and it is preursor of undifferentiated basal ce]1 epithelioma. Histological]y, the preparation showed massive development of sebaceous gland, papillomatous epidermal hyperplasia and maturation of apocrine glands. The tumor cell nests were mostly composed of large sheets of irregularly shaped cells in palisading pattern at the periphery. There were Iarge number of cells with vacuolated cytoplasm resembling sebaceous cell in certain part of the tumor cell masses and several keratin pearls. Diagnosis confirmed by clinical appearance and histological picture. These lesions could be treated sucessfully by wide excision.
Adult ; Apocrine Glands ; Carcinoma* ; Carcinoma, Basal Cell ; Cytoplasm ; Diagnosis ; Humans ; Hyperplasia ; Male ; Nevus* ; Nevus, Sebaceous of Jadassohn* ; Sebaceous Glands

The stability of the Knowles pinning in the intertrochanteric fractures of the femur was studied to determine which state would best support the load and compared with that of others. Experimental stable and unstable four-part fractures of the intertrochanteric region were produced by manual straight cut in 20 embalmed adult femora. These fracture were stabilized using accurate or inaccurate reduction combined with implant of Knowles pin parallel to calcar femorale or femoral neck. Those specimen were examined for the maximum load supported with the Universal Testing Machine. The results obtained are as follows: 1. Those femora of stable fracture with accurate reduction and Knowles pinning parallel to calcar femorale were failed by load of 140±13kg. 2. Those femora of stable fracture with accurate reduction and Knowles pinning parallel to femoral neck were failed by load of 120±11 kg. 3. Those femora of stable fracture with minimal displacement and Knowles pinning parallel to calcar femorale were failed by load of 110±10.4kg. 4. Those femora of unstable four-part fracture with accurate reduction and Knowles pinning parallel to calcar femorale were failed by 80±9kg.
Adult ; Femur Neck ; Femur ; Hip Fractures ; Humans

No abstract available.
Immunoglobulin E*

A case of tinea unguium caused by Aspergillus sydowi in 45 year old female was described. Through the literature this was the first case report in Korea, The characteristic clical findings noted the yellowish discoloration of the affeced nail which including KOH wet mount and culture. However, animal inoculation was failed.
Animals ; Aspergillus* ; Female ; Humans ; Korea ; Middle Aged ; Onychomycosis*

The objective of the present study was to identify the characteristics of phospholipase C (PLC) isozymes purified from bovine brain and to investigate their interrelationship with G protein. The purified PLC isozymes β, γ and δ were obtained and the characteristics of PLC activity on various concentrations of free Ca²⁺ were observed. The activity of PLC was increased with increasing Ca²⁺ concentration and the activity PLC δ was increased higher in the presence of phosphatidyl choline (PC) than in the absence of PC. For vesicle formation as the structure of cell membrane, cholic acid and deoxycholic acid as detergent on phosphatidylinositol bisphosphate (PIP₂) substrate containing PC were used, and then the activity of PLC isozymes were increased with increasing concentration of cholate, from 0.2% to 1% and were increased slightly in deoxycholate. In the PIP₂ containing phospholipid and glycolipid as brain extract, the activity of PLC isozymes were checked in 0.2-1% cholic acid. The activities of PLC isozymes were continuously increased up to 1% cholic acid. The quantitation of PLC isozymes from several bovine organs by radioimmunoassay was made. Brain was the most sufficient organ in terms of amount of PLC β and δ. A large amount of PLC δ was existed in adrenal gland. The binding capacity of GTPrS and G protein was observed and other observations of the binding effect of GTPrS-G protein and PLC monoclonal Ab-Protein A from tissue homogenate with PLC were made. From the observation the binding capacity was revealed the range of 0.11-1.49%. The effects of each type of G protein on the percent activity of purified PLC isozymes were observed. From the observation, activities of isozymes were increased in Goa & Gmix, and the activities of PLC β and δ were increased in Gβγ and Gia. Activities of PLC β and γ were decreased in Gta but PLC δ increased.
Adrenal Glands ; Brain* ; Cell Membrane ; Cholates ; Cholic Acid ; Choline ; Deoxycholic Acid ; Detergents ; GTP-Binding Proteins* ; Isoenzymes ; Phosphatidylinositols ; Phospholipases* ; Radioimmunoassay ; Type C Phospholipases*

Two cases of cutaneous sporotrichosis, especially one of which was verrucous type in baby aged 4 months, were described. Throush the literatures the verrucous manifestation in baby was not yet reported. It is known that verrucous sporotrichosis is to be developed in individual who has had local and general resistance obtained by the previous cutaneous infection or by the infection of internal organ. But no such evidences were noticed in our case.
Sporotrichosis*

A case of 24 years old male with perifolliculitis capitis abscedens et suffodiens was reported This is, I presume the first case to be reparted in Korea. Clinically, the skin lesions were characterized by tbe multiple confluented indolent abscesses and hypertrophic scars which were developed on the vertex. On these lesions, there were also noticed complete alopecia and several dilated hair follicle orifices plugged by keratinous materials. The regional lymphnodes were not enlarged and the abscesses were proved bacteriologically sterile.
Abscess ; Alopecia ; Cicatrix, Hypertrophic ; Hair Follicle ; Humans ; Korea ; Male ; Skin ; Young Adult

No abstract available.
Humans ; Laparotomy* ; Nephrectomy* ; Tissue Donors*