1.A Case of Azygos Vein Thombosis Associated with Transient Antiphospholipid Syndrome in Urinary Tract Infection with Escherichia coli.
Hong Joo LEE ; Young Mo KANG ; Eun LEE ; Byum Jin JEONG ; Young Jun JO ; Ji Seok SEONG ; Yong Moon WOO ; Kyung Hwan JEONG
Journal of Rheumatic Diseases 2016;23(2):118-121
A 73-year-old female with diabetes admitted for treatment of an intertrochanter fracture of the femur and a urinary tract infection (UTI) with Escherichia coli developed thrombosis in her right azygos vein, which was thought to be associated with antiphospholipid and immunoglobulin M anticardiolipin antibodies. After antibiotic therapy, antiphospholipid antibody was undetectable, and a repeat chest computed tomography showed complete resolution of the azygos vein thrombosis. A wide variety of infections can be associated with thrombotic events in patients with transient antiphospholipid syndrome (APS), and this case serves as a reminder that the possibility of transient APS should be considered in patients with venous thrombosis in the setting of a UTI.
Aged
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Antibodies, Anticardiolipin
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Antibodies, Antiphospholipid
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Antiphospholipid Syndrome*
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Azygos Vein*
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Escherichia coli*
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Escherichia*
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Female
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Femur
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Humans
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Immunoglobulin M
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Thorax
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Thrombosis
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Urinary Tract Infections*
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Urinary Tract*
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Venous Thrombosis
2.S-phase Fraction as an Independent Prognostic Factor in Invasive Breast Carcinoma -A Study of Long-term Follow-up.
Jin Hae BAE ; Jeong Won BAE ; Sang Uk WOO ; Chul Whan KIM ; Jae Bok LEE ; Gil Soo SON ; Byum Whan KOO
Journal of Breast Cancer 2007;10(1):36-42
PURPOSE: To evaluate the significance of the S-phase fraction (SPF) and DNA ploidy, determined by DNA flow cytometry, as prognostic markers in invasive breast cancer. METHODS: Between October 1986 and June 1999, 143 breast carcinoma patients, treated by surgery, were analyzed. Flow cytometry was performed for the identification of the SPF and DNA ploidy, with immunohistochemistry performed on paraffin embedded material for the hormone receptor. Two SPF classes were defined on the basis of the median value (10) by using a log rank test (high SPF>10, low SPF<10). The correlation between SPF and the clinicopathological factors (tumor size, lymph node status, histological grade and steroid receptor status) and between the SPF and 5 yr disease-free survival (DFS) were investigated. RESULTS: DNA ploidy was not associated with tumor size, lymph node status, histological grade, overall survival and DFS. In a univariate analysis, high SPF values were associated with shorter 5 yr DFS in individual groups. In the node negative group, the 5 yr DFS of the low SPF group was higher than that of the high SPF group, but in the node positive group, the SPF values showed statistical significance with the 5 yr DFS. In a multivariate analysis, the SPF was independently associated with the 5 yr DFS in the node negative group. CONCLUSION: These results suggested the SPF is an independent prognostic factor in lymph node negative, estrogen receptor positive and progesterone receptor negative breast cancers.
Breast Neoplasms*
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Breast*
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Disease-Free Survival
;
DNA
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Estrogens
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Flow Cytometry
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Follow-Up Studies*
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Humans
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Immunohistochemistry
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Lymph Nodes
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Multivariate Analysis
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Paraffin
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Ploidies
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Prognosis
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Receptors, Progesterone
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Receptors, Steroid