1.Effects of Temporary Amniotic Membrane Patch after Surgical Excision of Primary Pterygium.
Byoung Young GU ; Sang Bumm LEE
Journal of the Korean Ophthalmological Society 2012;53(6):749-760
PURPOSE: To investigate the clinical results, recurrence rates, and recurrence-related risk factors of temporary amniotic membrane patch (TAMP) after excision of primary pterygium. METHODS: Recurrence grade was evaluated for 73 eyes with a mean follow-up of 15.5 months (range 9 to 56 months). Surgical results were classified into surgical success (G0/G1), conjunctival recurrence (G2), and corneal recurrence (G3). Recurrence rates were analyzed based on gender, age, Tan's preoperative grading system, horizontal and vertical length of the preoperative pterygium, the corneal involvement size of the preoperative pterygium, planned or unplanned removal of amniotic membrane, and epithelial healing time. Using Kaplan-Meier survival analysis, the cumulative proportion of integrated G0/G1 was evaluated. RESULTS: In the postoperative grading, 58 (79.5%) and 9 (12.3%) eyes were graded as clinically recurrence-free G0 and G1, respectively; 4 (5.5%) and 2 (2.7%) eyes were graded as clinically recurrence-occurred G2 and G3, respectively. The cumulative proportion of integrated recurrence-free G0/G1 at 24 months after surgery was 0.83 +/- 0.08. T3 of Tan's preoperative grading system was identified as the only risk factor for recurrence above G1 through multivariate logistic regression analysis (p = 0.02). CONCLUSIONS: The recurrence rate of the present TAMP study showed better results in comparison with 9.1 to 56.1% of recurrence rates in other studies. The TAMP has advantages of surgical procedure with ease, low complications, and low recurrence rates. Therefore, after surgical excision of primary pterygium, the authors concluded the TAMP is highly recommended for good clinical outcomes and low recurrence rates.
Amnion
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Eye
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Follow-Up Studies
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Logistic Models
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Pterygium
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Recurrence
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Risk Factors
2.Clinical Study for External Fixators of Open Tibial Fractures
Ik Yull CHANG ; Young Kee CHUNG ; Kee Byoung LEE ; Byung Gu YOO
The Journal of the Korean Orthopaedic Association 1987;22(2):405-414
From August, 1981 to November, 19S5, the Hoffmann and Monofixateur apparatus were employed in the treatment of thirty five open tibial fractures that we considered to have a poor prognosis with more conventional forms of treatment. The results were obtained as follows; l. Application of Monofixateur was minimum iatrogenic soft tissue injuries and easier, simpler than Hoffmann and two external fixators were favorable device with rigidity in wound management. 2. Two external fixators could obtained sufficient stability when 3 or more pins were applied at each fragment of fracture in Hoffmann and 2 or more pins in Monofixateur. Monofixateur could obtained high stability with small number of fixation components and more stronger against anterior-posterior bending and in Hoffmann more stronger against lateral bending. 3. External components of Monofixteur was located in anterior surface, therefore dynamization converted tensile force of anterior surface of tibia to compression force and then bone union was activated. 4. After operation, in Hoffmann correction of compression, distraction and angular, rotational deformity were possible and in Monofixateur correction of compression distraction, and anterior or posterior angulation was possible. 5. Because of rigid stability of two external Bxators, these allowed early movement, avoiding joint stiffness and duration ambulation unilateral assembly of device in position biomechanically favorable. 6. The lateral view of fracture site could not be confirmed accurately due to overlapping of Hoffmann's adjustable connecting rod and bony shadow. In Monofixateur A-P and lateral view of Fx. site could be confirmed. 7. Accurate reduction and compression played a important role in bone union. 8. The time to fixation for all of the fractures averaged 20 weeks in Hoffmann and 16 weeks in Monofixateur. The time to union averaged 24 weeks in Hoffmann and 20 weeks in Monofixateur.
Clinical Study
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Congenital Abnormalities
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External Fixators
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Joints
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Prognosis
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Soft Tissue Injuries
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Tibia
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Tibial Fractures
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Walking
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Wounds and Injuries
3.Phacovitrectomy versus Vitrectomy only for Primary Rhegmatogenous Retinal Detachment Repair.
Byoung Young GU ; Min SAGONG ; Woo Hyok CHANG
Journal of the Korean Ophthalmological Society 2011;52(5):537-543
PURPOSE: To compare the outcomes of phacovitrectomy and vitrectomy only for treatment of primary rhegmatogenous retinal detachment. METHODS: The anatomical success, functional success, and complications between Group I patients who underwent vitrectomy only and Group II patients who underwent phacovitrectomy for primary rhegmatogenous retinal detachment were retrospectively compared. RESULTS: Twenty-one eyes (84.0%) in Group I had reattachment after vitrectomy only, and 27 eyes (90.0%) in Group II had reattachment after phacovitrectomy. However, the differences in the measures attributes were not statistically significant (p = 0.271). The logMAR visual acuity improved in both groups with no statistically significant difference between the two groups (p = 0.102). Postoperative complications included cataract progression in 20 eyes (80.0%) in Group I and 17 of the 20 eyes (68.0%) underwent cataract surgery within one year after the first surgery. CONCLUSIONS: Phacovitrectomy, irrespective of severe lens opacity, is a relatively effective combined surgical procedure in older patients with primary rhegmatogenous retinal detachment and impending presbyopia. The procedure allows for easy access to the periphery during vitreous shaving and prevents the need for a second cataract operation.
Cataract
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Eye
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Humans
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Phacoemulsification
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Postoperative Complications
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Presbyopia
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Retinal Detachment
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Retinaldehyde
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Retrospective Studies
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Visual Acuity
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Vitrectomy
4.Learning Curve for Endonasal Dacryocystorhinostomy.
Byoung Young GU ; Won Jae KIM ; Jun Hyuk SON
Journal of the Korean Ophthalmological Society 2011;52(5):519-523
PURPOSE: To determine the learning curve of dacryocystorhinostomy (DCR) performed by a single oculoplastic surgeon after one year of fellowship training. METHODS: This retrospective review study comprised nasolacrimal duct obstruction patients that underwent endonasal DCR at our hospital between February 2006 and February 2008. The patients that completed at least six months of follow-up were included in the analysis. Exclusion criteria were patients less than 20 years of age and NLD obstructions due to malignancy or canalicular obstructions. Success was defined as duct patency on syringing at the final follow-up and no complaints of epiphora. RESULTS: Out of 161 eyes, the overall surgical success rate was 83.2% (134/161 eyes) and the mean postoperative follow-up period was 6.5 months (6-18 months). Success rates gradually increased as follows: 71.2% (37/52 eyes) for the first group, 88.7% (47/53 eyes) for the second group, and 89.3% (50/56 eyes) for the third group (second and third group compared to first group, p = 0.025, p = 0.017, respectively). CONCLUSIONS: To ensure high DCR success rates, the novice surgeon should perform at least 50 surgeries.
Dacryocystorhinostomy
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Dietary Sucrose
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Eye
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Fellowships and Scholarships
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Follow-Up Studies
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Humans
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Learning
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Learning Curve
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Nasolacrimal Duct
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Retrospective Studies
5.A Demonhstration of a Tracheal Bronchus by Bronchoscopy and Computed Tompgraphy.
Byoung Gu KONG ; Youn Kyung LEE ; Eun Young JEONG ; Woo Ki LEE ; Kwang Woo KIM ; Jung Kon KOH
Journal of the Korean Pediatric Society 2000;43(11):1501-1504
Tracheal bronchus is an aberrant bronchus that arises most often from the right tracheal wall above the carina and is the result of an additional tracheal outgrowth early in embryonic life. It; incidence ranges between 0.1 and 5%. This anomaly is usually diagnosed incidentally during bronchoscopy, bronchography or computed tomography. Occasionally, it represents the underlying etiology for chronic pulmonary disease, especially if it involves the right upper lobe and reflects an abnorrnal pulmonary clearing mechanism. The tracheal bronchus may be associated with other bronchopulmonary anomalies, tracheal stenosis, or Down's syndrome. Asymptornatic tracheal bronchus does not require any treatment. In case of tracheal bronchus associated recurrent right upper lobe diseases, tracheal bronchus therapy should include resection of the aberrant bronchus as well as the lob it supplies. (J Korgan Pediatr Soc 2000;43:1501-1504)
Bronchi*
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Bronchography
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Bronchoscopy*
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Down Syndrome
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Equipment and Supplies
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Incidence
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Lung Diseases
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Tracheal Diseases
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Tracheal Stenosis
6.A case of Wernicke-Korsakoff syndrome associated with severe hyperemesis gravidarum.
Dong Gyu LEE ; Jun Young SEO ; Sun Jung GU ; Ok Rang PARK ; Hang Jin KIM ; Byoung Young KIM
Korean Journal of Obstetrics and Gynecology 2001;44(4):822-825
Hypermesis gravidarum is a complication defined as vomiting severe enough to require hospital admission during early pregnancy. Thiamine deficiency is known to lead to certain neurological seguelae including Wernicke-Korsakoff syndrome. Wernicke's encephalopathy is an illness of acute onset characterized by global confusion, paralysis of eye ball movements, and gate ataxia due to a deficiency of thiamine. The immediate administration of thiamine prevents progression of the disease and reverses brain lesions that have not yet progressed to the point of fixed structural change. We have experienced a case of Wernicke-Korsakoff syndrome associated with hyperemesis gravidarum, which seemed to be developed by prolonged thiamine-free fluid therapy. We emphasize the need for thiamine supplementation in hyperemesis gravidarum patients.
Ataxia
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Brain
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Female
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Fluid Therapy
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Humans
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Hyperemesis Gravidarum*
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Korsakoff Syndrome*
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Paralysis
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Pregnancy
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Thiamine
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Thiamine Deficiency
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Vomiting
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Wernicke Encephalopathy
7.Cytolagic Diagnosis of Colon Cancer by Colon Cleansing Solution.
Byoung Gu KIM ; Su Kyoung KIM ; Hyun Sun BAEK ; Duk Su CHO ; Eun Wha KIM ; Young Ou CHOI ; Young Yung LEE ; Hae Kyoung LEE
Korean Journal of Gastrointestinal Endoscopy 1996;16(6):945-951
Colorectal cancer consists of 8.2 percent of all malignancy in korea, and shows more increaing tendency. Despite the advances in the detection of calorectal cancer no single screening technique has achieved both high degree of diagnostic accuracy and minimal patient morbidity. We studied 24 patients, who underwent colonoscopy, with clinical suspicious colon cancer at Presbyterian Medical Center between Jan and Sep.1995, and evaluated the diagnostic feasibility of colon lavage cytology using oral cleansing solution.(continue...)
Colon*
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Colonic Neoplasms*
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Colonoscopy
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Colorectal Neoplasms
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Diagnosis*
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Humans
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Korea
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Mass Screening
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Protestantism
;
Therapeutic Irrigation
8.Cytolagic Diagnosis of Colon Cancer by Colon Cleansing Solution.
Byoung Gu KIM ; Su Kyoung KIM ; Hyun Sun BAEK ; Duk Su CHO ; Eun Wha KIM ; Young Ou CHOI ; Young Yung LEE ; Hae Kyoung LEE
Korean Journal of Gastrointestinal Endoscopy 1996;16(6):945-951
Colorectal cancer consists of 8.2 percent of all malignancy in korea, and shows more increaing tendency. Despite the advances in the detection of calorectal cancer no single screening technique has achieved both high degree of diagnostic accuracy and minimal patient morbidity. We studied 24 patients, who underwent colonoscopy, with clinical suspicious colon cancer at Presbyterian Medical Center between Jan and Sep.1995, and evaluated the diagnostic feasibility of colon lavage cytology using oral cleansing solution.(continue...)
Colon*
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Colonic Neoplasms*
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Colonoscopy
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Colorectal Neoplasms
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Diagnosis*
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Humans
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Korea
;
Mass Screening
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Protestantism
;
Therapeutic Irrigation
9.Nondestructive Assessment of Glycosaminoglycans in Engineered Cartilages Using Hexabrix-Enhanced Micro-Computed Tomography.
Long Hao JIN ; Byung Hyune CHOI ; Young Jick KIM ; Hyun Ju OH ; Byoung Ju KIM ; Xiang Yun YIN ; Byoung Hyun MIN
Tissue Engineering and Regenerative Medicine 2018;15(3):311-319
It is very useful to evaluate the content and 3D distribution of extracellular matrix non-destructively in tissue engineering. This study evaluated the feasibility of using micro-computed tomography (µCT) with Hexabrix to measure quantitatively sulfated glycosaminoglycans (GAGs) of engineered cartilage. Rabbit chondrocytes at passage 2 were used to produce artificial cartilages in polyglycolic acid scaffolds in vitro. Engineered cartilages were incubated with Hexabrix 320 for 20 min and analyzed via µCT scanning. The number of voxels in the 2D and 3D scanning images were counted to estimate the amount of sulfated GAGs. The optimal threshold value for quantification was determined by regression analysis. The 2D µCT images of an engineered cartilage showed positive correlation with the histological image of Safranin-O staining. Quantitative data obtained with the 3D µCT images of 14 engineered cartilages showed strong correlation with sulfated GAGs contents obtained by biochemical analysis (R² = 0.883, p < 0.001). Repeated exposure of engineered cartilages to Hexabrix 320 and µCT scanning did not significantly affect cell viability, total DNA content, or the total content of sulfated GAGs. We conclude that µCT imaging using Hexabrix 320 provides high spatial resolution and sensitivity to assess the content and 3D distribution of sulfated GAGs in engineered cartilages. It is expected to be a valuable tool to evaluate the quality of engineered cartilage for commercial development in the future.
Cartilage*
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Cell Survival
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Chondrocytes
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DNA
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Extracellular Matrix
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Glycosaminoglycans*
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In Vitro Techniques
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Ioxaglic Acid
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Polyglycolic Acid
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Tissue Engineering
10.Arteriovenous Malformation In Oral & Maxillofacial Region : A Case Report.
Na Young KIM ; Ki Hong KIM ; Seong Gon KIM ; Jung Gu LEE ; Byoung Ouck CHO
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2002;28(1):61-63
In the field of oromaxillofacial surgery, it is not common to meet arteriovenous malformation(AVM) patients. AVMs are the result of congenital abnormality, or the result of trauma of adjacent vessels. This patients need special care in surgical procedure. Also, they need management include clinical, radiographic, and angiographic assessment. We report a case of the AVM in right maxillary artery, who embolized PVA and obtained good result.
Angiography
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Arteriovenous Malformations*
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Congenital Abnormalities
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Humans
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Maxillary Artery