1.Trichorrhexis Nodosa: report of a case and Scanning Electron Microscopic Findings.
Yoon Kee PARK ; Byoung Moon CHOI ; Sung Nack LEE
Korean Journal of Dermatology 1982;20(3):473-477
Trichorrhexis nodosa is a distinctive response of the hair shaft to physical or chemical trauma, characterized by the development of node-like swelling, through which the shaft readily fractures. We have described here a case of trichorrhexis nodosa with scanning electron microscopic findings. Nodular swelling of the affected hair showed longitudinal fissures and fractures in the cortex with loss of cuticular scales. At the site of fracture, a paintbrush-like effect was seen.
Hair
;
Weights and Measures
2.Electromicroscopic Characterization about Vibrio alginolyticus Phage Isolated from Marine Products.
Jin Woo JU ; Seong A JU ; Moon Soo HEO ; So Gyem YOON ; Joo An OK ; Byoung Gon MOON
Journal of the Korean Society for Microbiology 1997;32(1):91-101
The study of bacteriophage began by F.W. Twort in 1915 and the lytic cycle recognized by d'Herellel in 1917. It repeated about the marine bacteriophage containing Vibrio phage by Smith, Spencer and Ju. Authors isolated 2 virulent phages for the pathogenic V. alginolyticus from marine products. These 2 phages were examined their ultrastructure & host-infection by elecron microscopy and in vivo test using skin of rats. V. alginolyticus phages(VAPs) fomed plaques about 0.5 - 0.9mm in diameter and bands 50 - 60% in sucrose density gradient. VAP had 50 - 120nm tail and 40 - 90nm head in diameter. In vivo test, using rat skin, as well as in vitro test VAP had the activity to V. alginolyticus isolated.
Animals
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Bacteriophages*
;
Coriolaceae
;
Head
;
Microscopy
;
Rats
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Skin
;
Sucrose
;
Tail
;
Vibrio alginolyticus*
;
Vibrio*
3.A case of Henoch-Schonlein purpura nephritis preceded by acute abdomen.
Sung Yoon CHO ; Byoung Soo CHO ; Yong Koo PARK ; Moon Ho YANG
Journal of the Korean Academy of Family Medicine 1992;13(1):79-84
No abstract available.
Abdomen, Acute*
;
Nephritis*
;
Purpura, Schoenlein-Henoch*
4.Clinical observation for postterm pregnancy.
Byoung Tae LEE ; Moon Su KIM ; Young In KIM ; Kyoung Ho LEE ; Heung Gi KWON ; Yoon Sun LEE ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1992;35(7):973-981
No abstract available.
Pregnancy*
5.Active management of premature rupture of membranes at or near term using PGE2 vaginal suppository.
Byoung Young LEE ; Jae Young LEE ; Yoon Keun HUR ; Sin Wook KIM ; Hee Jin SEUNG ; Moon Soo SUNG
Korean Journal of Perinatology 1993;4(2):215-223
No abstract available.
Dinoprostone*
;
Membranes*
;
Rupture*
;
Suppositories*
6.Bacteriology of the biliary tract.
Byoung Seon RHOE ; Sung Sang MOON ; Nam Cheon CHO ; Kwang Soo YOON ; Dae Sung KIM ; Kyung Won LEE
Journal of the Korean Surgical Society 1992;43(3):364-370
No abstract available.
Bacteriology*
;
Biliary Tract*
7.A Case of Penetrating Cranial Injury by a Wooden Foreign Body.
Yeong Tae KIM ; Sung Moon YOON ; Byoung Jo JANG ; Young Woo LEE
Journal of Korean Neurosurgical Society 1986;15(4):855-860
Many objects create penetrating cranial injuries. Metallic objects and low velosity missiles are the most common offenders. Wood as wounding agent of the brain, has some characteristics. It has profound risk of infection, a significant propensity to fragmentation that is virtually undetechable on routine X-ray screening and very low atteunation value in CT scan. Because of its characteristics and rarity, we report a case of penetrating cranial injury by a wooden foreign body with review of literature.
Brain
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Criminals
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Debridement
;
Foreign Bodies*
;
Humans
;
Mass Screening
;
Tomography, X-Ray Computed
;
Wood
;
Wounds and Injuries
8.Hyperinsulinemia in Patients with Chest Pain and Normal Coronary Angiograms.
Kwi Soon LEE ; Hyuck Moon KWON ; Byoung Kwon LEE ; Dong Hoon CHA ; Young Won YOON ; Hyun Seung KIM
Korean Circulation Journal 1995;25(5):960-966
BACKGROUND: Angina with normal coronary angiogram has been called syndrome X or microvasclar angina. Pathophysiologic mechanisms for chest pain in this group of patients are not known exactly. This study was performed to compare the insulin level of the patients with syndrome X with that of the healthy asymptomatic volunteers. METHODS: The syndrome X group was consisted of 18 patients(11 men and 7 women). All patients had typical chest pain and positive exercise test with a completely normal coronary andgiogram. Patients with hypertension, diabetes mellitus, and there taking any drug known to affect the insulin secretion were excluded. The control group was consisted of 38 healthy subjects(25 men and 11 women) who were not taking any medications. We measured the plasma glucose insulin and C-peptide concentration during oral glucose tolerance test in both groups. RESULTS: Fasting plasma glucose was normal in all patients in both groups. There were no significant differences in plasma glucose level, during the oral grucose tolerance test. There were no significant differences between control and wyndrome X group in the fasting plasma insulin concentration(5.1+/-2.4 vs 5.9+/-2.7 microg/ml, p>0.05). However, the insulin levels at 60min(47.6+/-20.0 vs 84.0+/-68.0 microg/ml) and 120 min(31.4+/-18.2 vs 92.9+/-83.8 microg/ml)were significantly higher in the syndrome X group(p<0.05). THere were no significant differences in the C-peptide concentrations at fasting, 60 min and 120 min after oral glucose tolerance test between control and syndrome X group(p>0.05). CONCLUSION: As shown in above results, there were significant differences in insulin concentrations, but nor in C-peptide concentrations between control and syndrome X group. Thus it can be suggested that the increased dinsulin level in these patients is resulted from the altered insulin action to the target tissues, not from the pancreatic overproduction of insulin. We suggest that this hyperinsulinemia resulted from the insulin resistance play a possible role in the abnormality of microvascular circulation as a mechanism of Syndrome X.
Blood Glucose
;
C-Peptide
;
Chest Pain*
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Diabetes Mellitus
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Exercise Test
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Fasting
;
Glucose Tolerance Test
;
Humans
;
Hyperinsulinism*
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Hypertension
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Insulin
;
Insulin Resistance
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Male
;
Plasma
;
Thorax*
;
Volunteers
9.A proposal of staging system in chronic sinusitis.
Ki Yeun KIM ; Seog In PAIK ; Soon Il PARK ; Byoung Moon YOON ; Jong Chan HONG ; Dong Joon PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):713-720
No abstract available.
Sinusitis*
10.Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells.
Seo Hwa KIM ; Moon Seong BAEK ; Dong Sik YOON ; Jong Seol PARK ; Byoung Wook YOON ; Byoung Su OH ; Jinkyeong PARK ; Hui Jung KIM
Tuberculosis and Respiratory Diseases 2014;77(2):73-80
BACKGROUND: Low levels of serum vitamin D is associated with several lung diseases. The production and activation of matrix metalloproteinases (MMPs) may play an important role in the pathogenesis of emphysema. The aim of the current study therefore is to investigate if vitamin D modulates the expression and activation of MMP-2 and MMP-9 in human lung fibroblasts (HFL-1) cells. METHODS: HFL-1 cells were cast into three-dimensional collagen gels and stimulated with or without interleukin-1beta (IL-1beta) in the presence or absence of 100 nM 25-hydroxyvitamin D (25(OH)D) or 1,25-dihydroxyvitamin D (1,25(OH)2D) for 48 hours. Trypsin was then added into the culture medium in order to activate MMPs. To investigate the activity of MMP-2 and MMP-9, gelatin zymography was performed. The expression of the tissue inhibitor of metalloproteinase (TIMP-1, TIMP-2) was measured by enzyme-linked immunosorbent assay. Expression of MMP-9 mRNA and TIMP-1, TIMP-2 mRNA was quantified by real time reverse transcription polymerase chain reaction. RESULTS: IL-1beta significantly stimulated MMP-9 production and mRNA expression. Trypsin converted latent MMP-2 and MMP-9 into their active forms of MMP-2 (66 kDa) and MMP-9 (82 kDa) within 24 hours. This conversion was significantly inhibited by 25(OH)D (100 nM) and 1,25(OH)2D (100 nM). The expression of MMP-9 mRNA was also significantly inhibited by 25(OH)D and 1,25(OH)2D. CONCLUSION: Vitamin D, 25(OH)D, and 1,25(OH)2D play a role in regulating human lung fibroblast functions in wound repair and tissue remodeling through not only inhibiting IL-1beta stimulated MMP-9 production and conversion to its active form but also inhibiting IL-1beta inhibition on TIMP-1 and TIMP-2 production.
Collagen
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Emphysema
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Enzyme-Linked Immunosorbent Assay
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Fibroblasts*
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Gelatin
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Gels
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Humans
;
Interleukin-1beta
;
Lung Diseases
;
Lung*
;
Matrix Metalloproteinase 9
;
Matrix Metalloproteinases
;
Polymerase Chain Reaction
;
Reverse Transcription
;
RNA, Messenger
;
Tissue Inhibitor of Metalloproteinase-1
;
Tissue Inhibitor of Metalloproteinase-2
;
Trypsin
;
Vitamin D*
;
Wounds and Injuries