Atypical fibroxanthoma(AFX) occurs most on sun-exposed area of the head and neck of elderly person. It has an excellent prognosis after conservative, but complete, excision. However, because of its potential, albeit small, for metastasis, it is widely regarded as a low-grade sarcoma. We present herein two cases of atypical fibroxanthoma. The case 1 was a 86-year-old female who had a small egg-sized, dome shaped nodule with eroive surface on the left cheek. The other case was a 60-year-old male who had solitry bean-sized, nodulo-ulcerative lesion on the vertex. Immunohistochemical studies revealed positive reaction for vimntin and a-antichymo trypsin. These patients have received completely total surgical ecis on and remained free of recurrence for a period of about, 2 years follow up.
Aged ; Aged, 80 and over ; Cheek ; Female ; Follow-Up Studies ; Head ; Humans ; Male ; Middle Aged ; Neck ; Neoplasm Metastasis ; Prognosis ; Recurrence ; Sarcoma ; Skin* ; Trypsin

No abstract available.
Colon* ; Humans* ; Morphine* ; Naloxone* ; Perfusion*

Isolated adrenocorticotropic hormone (ACTH) deficiency is an uncommon disorder for which the pathogenetic mechanism has not yet been identified. It has been reported that isolated ACTH deficiency (ICD) may be accompanied by deficiencies in other pituitary hormones; impaired growth hormone (GH) secretion was noted in 20 to 30% of ICD patients. Here, we describe a female patient with isolated ACTH deficiency accompanied by empty sella syndrome presenting as hypoglycemia, which was confirmed via various endocrine tests and magnetic resonance imaging (MRI) of the sella turcica. The patient's symptoms improved rapidly with prednisolone therapy and, during follow-up, her previously impaired GH response to provocative stimuli and high TSH levels were corrected by glucocorticoid replacement alone. However, treatment failed to normalize plasma IGF-1 levels, suggesting that physiological cortisol levels are necessary for a normal plasma GH response to provocative stimuli.
Adrenal Insufficiency ; Adrenocorticotropic Hormone ; Empty Sella Syndrome ; Female ; Follow-Up Studies ; Growth Hormone ; Humans ; Hydrocortisone ; Hypoglycemia ; Insulin-Like Growth Factor I ; Magnetic Resonance Imaging ; Plasma ; Prednisolone ; Sella Turcica

This paper reports a case of malignant histiocytic lymphoma mainly in the frontal region with intracranial extradural extension. Operation was performed to remove the mass but the tumor began to recur rapidly. And so under the condition that the operative wound was not fully healed, the patient received radiotheray and chemotherapy postoperatively, with remarkable regession of the tumor.
Drug Therapy ; Humans ; Lymphoma ; Lymphoma, Large B-Cell, Diffuse* ; Scalp* ; Wounds and Injuries

Oligodendroglioma that occurs in the ventricle has been reported uncommonly. The case is reported of a 38-year-old man who presented with severe headache and vomiting and was discovered to have an oligodendroglioma in the lateral and third ventricles. The clinical presentation, radiological finding, pathology and response to radiation are described with brief review of general biology in oligodendroglioma.
Adult ; Biology ; Headache ; Humans ; Lateral Ventricles ; Oligodendroglioma* ; Pathology ; Third Ventricle* ; Vomiting

We report a case of immature teratoma arising at the suprasellar region in a 18 year-old-male who presented with bitemporal hemianopsia, nausea and polydipsia. The teratoma is a rare neoplasm consisting of 0.5% to 1.2% of all intracranial tumors. The clinical presentation, radiologic finding, pathology and treatment are briefly described with a review of other cases from the literature in view of clinical features and management.
Chemoradiotherapy ; Hemianopsia ; Nausea ; Pathology ; Polydipsia ; Teratoma*

Myasthenia gravis and autoimmune thyroid disorders often overlap. It is known that hyperthyroidism occurs in 2~17.5% of patients with myasthenia gravis. Thyrotoxicosis may influence the clinical course of myasthenia gravis. Overlapping clinical features may cause diagnostic confusion when Graves' disease and myasthenia gravis co-exist. Thus, various tests may be needed to distinguish these two diseases. It is clinically important to screen patients with myasthenia gravis for the co-existence of autoimmune thyroid disorders and vice versa. We cared for a patient with Graves' disease associated with ocular myasthenia gravis who presented with fluctuating double vision and ptosis. Ocular myasthenia gravis was diagnosed by electrophysiologic study and presence of acetylcholine receptor antibody. The patient had a favorable clinical and laboratory response to treatment with an anticholinesterase (pyridostigmine) and an antithyroid drug (propylthiouracil), and he had minimal symptoms at the 9-month follow-up examination.
Acetylcholine ; Diplopia ; Follow-Up Studies ; Graves Disease ; Humans ; Hyperthyroidism ; Myasthenia Gravis ; Thyroid Gland ; Thyrotoxicosis

A large tumor located at right temporoparietal lobe was found in 25-years-old female. The brain CT scan and MR imaging revealed a large multi-lobulated mass which was composed of solid and cystic portions involving right temporoparietal lobe. Preoperative routine laboratory check showed microcytic hypochromic anemia and monoclonal gammopathy with bate-gamma bridging. The mass was removed totally by operation and histologic diagnosis resulted in chordoid meningioma surrounded by massive polyclonal lymphoplasmacellular infiltrates. After the mass was removed, the blood picture of the patient normalized and the patient discharged with neurologically free stage. We report this case with relative literatures.
Anemia, Hypochromic ; Brain ; Diagnosis ; Female ; Humans ; Magnetic Resonance Imaging ; Meningioma* ; Paraproteinemias ; Tomography, X-Ray Computed

We analyzed 54 cases of spontaneous intracerebral hematoma in the basal ganglia who had been admitted to Pusan National Hospital from June, 1991 to December, 1992 and underwent CT-guided stereotactic aspiration. Fifity four cases had basal ganglia hematoma with or without ventricular rupture. In 12 cases out of them, the residual hematoma could be completely evacuated by urokinase irrigation through a catheter introduced into the cavity of hematoma. Patients with preoperatively poor neurologic condition, large or deep-seated hematoma, or the operation undergone before 6 hours from ictus, had worse outcome. In the case whose hematoma was removed more than 60%, Glasgow Outome Scales were not changed significantly. Patients of spontaneous intracerebral hematoma mostly are older age, so careful observation and medical treatment are required to prevent postoperative complications and improve general condition.
Basal Ganglia* ; Busan ; Catheters ; Hematoma* ; Humans ; Postoperative Complications ; Rupture ; Urokinase-Type Plasminogen Activator ; Weights and Measures

Ganglionneuroma is slow-growing benign neoplasm that orignates from the sympathetic nervous system. A case of dumb-bell shaped Ganglionneuroma at first and second cervical areas is presented on this paper with chief complaint of neck pain and quadriparesis. The tumor was totally removed under operating microscope and the diagnosis was pathohistologically confirmed. The postoperative result was good and relative literatures were reviewed.
Diagnosis ; Ganglioneuroma* ; Neck Pain ; Quadriplegia ; Sympathetic Nervous System