1.Schizophrenia, schizotypal and delusional disoeders: a field trial of DCR-10 1990 draft(1).
Byoung Hoon OH ; Joo Hoon LEE ; Byum Young LEE
Journal of Korean Neuropsychiatric Association 1992;31(2):310-319
No abstract available.
Delusions*
;
Schizophrenia*
2.Fracture of Capitellum Humeri in Weight Lifting Athlete: A Case Reprt
Kee Byoung LEE ; Jin Young LEE ; Young Hoon KIM
The Journal of the Korean Orthopaedic Association 1989;24(6):1739-1743
Fracture of capitellum humeri, so called Kocher fracture, was first described by Haln in 1853. It is rare and has been occured 0.5% to 1% of incidence of all elbow fracture. The mechanism of this fracture mostly results when one tries to break a fall and lands on the hand with the elbow in some degree of flexing or falls directly on the elbow in a position of full flexion. This case had been occured in a secondary motion
Accidental Falls
;
Athletes
;
Elbow
;
Hand
;
Humans
;
Incidence
;
Methods
;
Weight Lifting
3.Effects of hypoxia on rat brain norepinephrine, dopamine and serotonin contents.
Chang Joo KIM ; Moo Hoon LEE ; Byoung Ok PARK
Korean Journal of Aerospace and Environmental Medicine 1993;3(2):56-59
No abstract available.
Animals
;
Anoxia*
;
Brain*
;
Dopamine*
;
Norepinephrine*
;
Rats*
;
Serotonin*
4.Changes in Blood Superoxide Dismutase Activities after Alcohol Withdrawal.
Jin Sook CHEON ; Kyu Cheon LEE ; Byoung Hoon OH
Journal of the Korean Society of Biological Psychiatry 1999;6(2):219-226
OBJECTIVES: The aims of this study were to evaluate changes in plasma superoxide dismutase(SOD) activities in alcohol depedence, to fine out variables to influence on the SOD activities, and finally to identify the correlation of SOD activities with the alcohol-associated cognitive disorders. METHODS: For 24 male alcoholics and 21 healthy male controls, plasma SOD activities were measured by spectrophotometry on 1-2 wks after alcohol withdrawal. Structured interviews and laboratory tests were also performed. RESULTS: 1) Upon comparing SOD activities between controls and alcoholics, the SOD activities were significantly(p<0.01) lower in alcoholics(0.308+/-0.140 units/mL) than in healthy controls(0.313+/-0.086 units/mL). 2) Upon comparing SOD activities according to the presence of alcohol-related cognitive disorders, the SOD activities were significantly(p<0.05) lower in alcoholics with cognitive disorders(0.247+/-0.049 units/mL) than in alcoholics without cognitive disorders(0.317+/-0.148 units/mL). 3) Upon comparing SOD activities according to the presence of alcoholic polyneuropathy or alcohol withdrawal seizure, the SOD activities showed no significant differences between alcoholics with polyneuropathy or epilepsy and those without. 4) Upon analyzing variables influencing on the SOD activities in alcoholics, the SOD activities had the negative correlation with hemoglobin(gamma=-0.433) and severity of alcohol withdrawal symptoms(gamma=-0.375). 5) Upon comparing variables according to the presence of alcohol-related cognitive disorders, the occurrence of alcoholic polyneuropathy(p<0.05) and blood phosphorus concentrations(p<0.01) were significantly higher in alcoholics with cognitive disorders than those without. 6) Upon analyzing an association between SOD activities and variables in alcoholics with cognitive disorders, the SOD activities were positively correlated with the onset age(gamma=0.995), and negatively correlated with the severity of alcohol withdrawal symptoms(gamma=-0.996). CONCLUSIONS: Lower SOD activities in alcohol dependence suggested alcohol-associated cognitive disorders and alcohol withdrawal symptoms might be caused by oxidative stress.
Alcohol Withdrawal Seizures
;
Alcoholic Neuropathy
;
Alcoholics
;
Alcoholism
;
Epilepsy
;
Humans
;
Male
;
Oxidative Stress
;
Phosphorus
;
Plasma
;
Polyneuropathies
;
Spectrophotometry
;
Substance Withdrawal Syndrome
;
Superoxide Dismutase*
;
Superoxides*
5.The Influence of Estrogen on Dopamine Metabolites in Schizophrenia.
Jin Sook CHEON ; Jang hyun LEE ; Byoung Hoon OH
Journal of the Korean Society of Biological Psychiatry 1999;6(2):209-218
OBJECTIVES: The aims of this study were to discriminate the clinical differences, to measure the estrogen and homovanillic acid levels. to evaluate a correlation between estrogen and homovanillic acid. and to identify an association of cognitive deficit with estrogen and homovanilli acid among male and female schizophrenics. METHODS: In addition to the structured interviews, the plasma estrogen levels by radioimmunoassay and the homovanillic acid levels by HPLC were measured in 20 male and 21 female schizophrenics as well as 10 healthy male and 9 female controls. RESULTS: 1) The plasma estrogen levels were higher in females than males, and significantly higher in female schizophenics than female controls. The homovanillic acid levels were higher in female schizophrenics than female controls, and were lower in male schizophrenics than male controls. 2) The onset age seemed to be earlier in male schizophrenics, and the frequency of admission, duration of antipsychotic drug administration. dosage of antipsychotics and duration of illnesses were more in males. The estrogen and homovanillic acid levels were significantly higher in female schizophrenics. 3) The estrogen levels had a significant positive correlation with sex, age and onset age, while the homovanillic acid levels did with sex. However, estrogen wee not correlated with homovanillic acid levels. 4) The estrogen and homovanillic acid levels were not significantly different between male and female schizophrenics with cognitive deficits. In the schizophrenic patients without cognitive deficits, the estrogen levels were significantly higher in females, while here were no significant sex differences in homovanillic acid. 5) In the male and female schizophrenics predominantly with negative symptoms, there were no significant differences in estrogen and homocanillic acid levels. In those predominantly with positive symptoms, the estrogen levels wee significantly higher in females, while there were no sex differences in homovanillic acid levels. 6) In schizophrenics with undifferentiated subtype, the estrogen and homovanillic acid levels were significantly higher in females. In those with paranoid or disorganized subtypes. the estrogen levels were significantly higher females, while there were no sex differences in the homovanillic acid levels. 7) The mean values of PANSS-negative. PANSS-total, PANSS-CF, MMSE-K and estrogen levels were significantly higher in male schizophrenics with cognitive deficits. The mean values of illness duration, CGI PANSS-positive, PANSS-negative, PANSS-total, PANSS-CF and MMSE-K were significantly higher in female schizophrenics with cognitive deficits. 8) The variables which showed significant correlation with cognitive deficits were PANSS-nagative, PANSS-total, PANSS-CF, MMSE-K and estrogen levels in male schizophrenics. The variables which showed significant correlation with cognitive deficits were subtypes, onset age, illness duration, CGI, PANSS-positive, PANSS-negative, PANSS-total, PANMSS-CF and MMSE-K in female schizophrenics. The estrogen levels were significantly correlated with admission frequencies, history of antipsychotic administration, duration of antipsychotic administration and cognitive deficits in male schizophrenics. while age were not correlated with in females. The homovanillic acid levels had a significant correlation with subtypes and onset age in male schizophrenics, while there were no correlation among variables in females. CONCLUSIONS: Although the plasma concentrations of estrogen and homovaillic acid in female schizophrenics were significantly higher than males, we could not find an association between them. Furthermore, the various factors affecting on the cognitive deficits, estrogen and homovanillic acid levels seemed to be somewhat different according to sex.
Age of Onset
;
Antipsychotic Agents
;
Chromatography, High Pressure Liquid
;
Dopamine*
;
Estrogens*
;
Female
;
Homovanillic Acid
;
Humans
;
Male
;
Plasma
;
Radioimmunoassay
;
Schizophrenia*
;
Sex Characteristics
6.Biomechanical Properties of the Growing Long Bone
Han Koo LEE ; Duk Yong LEE ; Sang Hoon LEE ; Byoung Wan AHN ; Chin Youb CHUNG
The Journal of the Korean Orthopaedic Association 1987;22(2):356-368
Bone is a heterogenous and anisotrophic material exhibiting elastic, viscoelastis and plasticproperties. A considerable amount of information is now available regarding biomechanical properties and mechanisms of fractures of mature long bones, but less is known about the properties of the growing bones. In order to assess the biomechanical properties under tension, rabbits growing bones were loaded with Instron Modal 1,000 until fracture occurred. Two hundred tibiae of 100 New Zealand white immature rabbits were divided into 6 experimental groups according to maturity and size. Group I-R(40 right tibiae of 1-month old rabbits), Group I-L (40 left tibiae of 1-month old rabbits), Group II-R(20 right tibiae of 3-month old rabbits), Group II-L (20 left tibiae of 3-month old rabbits), Group III-R(40 rigth tibiae of 5-month old rabbits), and Group III-L(40 left tibiae of 5-month old rabbits). The following results were obtained. 1. Fracture type was transverse.or nearly transverse in 170 out of the total 200 tibiae(85%).
Absorption
;
Elastic Modulus
;
New Zealand
;
Rabbits
;
Tensile Strength
;
Tibia
7.Clinical Observations of Meningitis.
Byoung Hoon LEE ; Myung Ik LEE ; Hyung Keun NAM ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1989;32(2):180-190
No abstract available.
Meningitis*
8.Clinical Evaluation of Gastric Juice Culture of Newborn.
Byoung Hoon LEE ; Back Hee LEE ; Soon Wha KIM ; Keum Chan SOHN
Journal of the Korean Pediatric Society 1989;32(3):342-348
No abstract available.
Gastric Juice*
;
Humans
;
Infant, Newborn*
9.A Case of Laurence-Moon-Biedl Syndrome Including Diabetic Mellitus.
Byoung Hoon LEE ; Byung Rai CHO ; Myoung Ik LEE ; Keun Chan SOHN ; Hyung Joon YOO
Journal of the Korean Pediatric Society 1989;32(6):857-861
No abstract available.
Laurence-Moon Syndrome*
10.A Case of Laurence-Moon-Biedl Syndrome Including Diabetic Mellitus.
Byoung Hoon LEE ; Byung Rai CHO ; Myoung Ik LEE ; Keun Chan SOHN ; Hyung Joon YOO
Journal of the Korean Pediatric Society 1989;32(6):857-861
No abstract available.
Laurence-Moon Syndrome*