No abstract available.
Child* ; Humans ; Mass Screening*

No abstract available.
Rickets*

A case of primary malignant fibrous histiocytoma(MFH) of the lung occurring in a 62-year-old man is presented. After preoperative bronchial brushing and washing cytologic diagnosis of poorly differentiated carcinoma, surgical resection and lymph nodes dissection were performed. Subsequent histologic examination revealed a primary MFH. The diagnosis was confirmed by electron microscopic and immu- nohistochemical examinations. The review of the bronchial brushing and washing cytologic features disclosed many bipolar and a few unipolar spindle tumor cells with a "comet" configuration, mainly single cells, but also forming loose clusters. The nuclei were elongated and hyperchromatic and contained one or more irregular nucleoli. Scattered bizarre, multinucleated tumor giant cells were also present.
Carcinoma, Papillary ; Child* ; Diagnosis ; Giant Cells ; Humans ; Korea* ; Lung ; Lymph Nodes ; Middle Aged ; Nephrotic Syndrome* ; Thyroid Gland

CT guided percutaneous fine-needle aspiration (FNA) of the liver for both cytologic and histologic examination has great value in diagnosing liver malignancy. From March, 1986 to April, 1990, 62 patients with the clinical impression of liver mal- ignancy underwent CT guided percutaneous FNA biopsy. Of these, 43 cases were revi- ewed for this study, 19 were reported to be liver cell carcinoma, 2 were adenocarcinoma, 11 were reported as anaplastic cell present, and the rest (11 cases) were negative (9) or necrotic (2). Among the 11 cases of the last group, 9 were diagnosed as liver cell carcinoma and 2 were necrotic histologically. Retrospective review, in order to clarify the cause of cytologic diagnostic error, of both cytologic and histologic slides of all cases showed discordance of 23% between these diagnoses and sensitivity is 93.9% and specificity is 90.9%. The reasons were as follows ; 1) the lack of awareness of tumor cells of well differentiated liver cell carcinoma (4 cases), 2) missed tumor cells due to too scanty cellularity (1 case), 3) improper smear (2 cases) and no tumor cell in the cytologic smears (3 cases). In such cases, at the initiation of FNA, a correct diagnosis of liver malignancy could only be made by a combination of cytologic and histologic examinations. However after three years' exper- ience we can conclude that cytomorphologic features of liver cell carcinoma are sufficiently distinctive from other liver malignancies to be diagnostic.
Adenocarcinoma ; Biopsy ; Biopsy, Fine-Needle ; Carcinoma, Hepatocellular ; Diagnosis ; Diagnostic Errors ; Humans ; Liver ; Nephrotic Syndrome* ; Retrospective Studies ; Sensitivity and Specificity

No abstract available.
Adult* ; Child* ; Chin* ; Humans

No abstract available.
Animals ; Histamine Release* ; Histamine* ; Mast Cells* ; Rats*

No abstract available.
Mesenchymal Stromal Cells* ; Osteogenesis*

PURPOSE: To analyze the variable MRI features and clinical significance of intracranial cavernous realformation. MATERIALS AND METHODS: Forty patients(mean age 35.4) with cavernous malformation were evaluated by MRI. Eleven patients were surgically confirmed. Cavernous malformations were divided into four categories on the basis of the MR imaging characteristics, especially on T2-weighted image. Type I lesion was defined as an extralesional subacute hemorrhage outside the low signal rim, type II as an intralesional hemorrhage surrounded by low signal rim, type III lesion as an intralesional thrombosis with variegated central core surrounded by low signal rim, and type IV lesion as a focal old hemorrhagic core with small low signal intensity. Type IV was further divided into IVa and IVb, whether the lesion has small iso- or hypersignal central core (IVa) or not (IVb). Follow-up MRI was evaluated in 12 patients who were managed conservatively. Follow-up intervals ranged from 2 weeks to 29 months (mean 6months). RESULTS: Total 80 lesions were detected in 40 patients. Multiple lesions were noted in 10 patients. The topography of the cavernous malformations was supratentorial in 75% and infratentorial in 23%. There were 10 lesions in type I, 15 in type 11, 21 in type III, 14 in type IVa, and 20 in type IVb. Type I lesions mainly showed mass effect and edema. Type III lesions showed minimal contrast enhancements in 7 lesions on delayed images. Type II lesions showed the characteristics of both type I and type III lesions. On follow up images, decrease in size in 5, change of type in 7, rebleeding in 2 and no change in 12 lesions were demonstrated. Hemorrhage, edema and mass effect were combined in the cases of rebleeding. On follow-up study, the estimated risk of bleeding was 32.3%/person-year and 13.7%/lesion-year. CONCLUSION: Cavernous realformations show as variable appearance, on MR imaging suggesting variable stages of evolution. The MR morphologic classification and evaluation of secondary findings are helpful to predict natural course and possibility of rebleeding of the lesion.
Classification ; Edema ; Follow-Up Studies ; Hemorrhage ; Humans ; Magnetic Resonance Imaging* ; Thrombosis

Meningioma is the most common neoplasm of central nervous system which is hardly diagnosed by cytologic examination. However, preoperative cytologic diagnosis can be easily made in the case of extracranial meningioma, especially in head and neck lesion. We recently experienced a case of fine needle aspiration cytology of meningioma in submandibular area of a 24 year-old male patient. The smear revealed high cellularity in the clean background. Individual tumor cell of nests or syncytium had round or oval nuclei with fine chromatin and moderate amount of lightly stained cytoplasm with indistinct mar- gin. Characteristic cellular whorls, intranuclear inclusions and scattered psammoma bodies made it easy to diagnose a meningioma.
Biopsy, Fine-Needle ; Carcinoma, Small Cell ; Central Nervous System ; Chromatin ; Cytoplasm ; Diagnosis ; Fanconi Syndrome* ; Giant Cells ; Head ; Humans ; Intranuclear Inclusion Bodies ; Male ; Meningioma ; Neck ; Salivary Glands ; Young Adult

No abstract available.
Immunoglobulin M*