No abstract available.
Prurigo

No abstract available.
Hypopigmentation ; Lichens

The glucose uptake rate by Eurytrema pancreaticum was a mean value of 16.44 +/- 2.42 micro-mole/hr/g, and total CO(2) production rate by the fluke averaged 5.82 +/- 0.97 micro-mole/hr/g. The relative specific activity of respiratory CO(2) showed a mean value of 5.75 +/- 0.84 per cent. The rate of CO(2) production derived from medium C(14)-glucose was a mean of 0.33 +/- 0.10 micor-mole/hr/g. Therefore, the average value of 0.32 +/- 0.04 per cent of glucose utilized by the flukes from the medium C(14)-glucose was oxidized to respiratory CO(2). The tissue concentration of glycogen in E. pancreaticum was a mean of 45.50 +/- 2.18 mg/g or 4.55 +/- 0.22 %/g. But the turnover rate of glycogen pool was a mean of 0.027 +/- 0.003 %/hr or 0.009 +/- 0.002 mg/hr/g. The average value of 0.64 +/- 0.23 percent of glucose utilized by the flukes from the medium C(14)-glucose was incorporated into the glycogen. These data account for that only 1 per cent of the utilized glucose by the flukes participated in furnishing the oxidation into respiratory CO(2) and the synthetic process into glycogen.
parasitology-helminht-trematoda- Eurytrema pancreaticum ; glucose-biochemistry ; autoradiograhy ; glucose ; glycogen ; CO(2)

BACKGROUND: The histologic distinction of dermatofibrosarcoma protuberans (DFSP) and dermatofibroma (DF) may be difficult, especially in the case of DF extending into the subcutaneous fat. CD34 and Factor XIIIa stains are commonly used in distinguishing the DF from DFSP, but is not always helpful. There are no studies regarding the clinicopathologic comparison of DF and DFSP. OBJECTIVE: The aim of our study was to evaluate the clinicopathologic characteristics and differences between the DF and DFSP. METHODS: Retrospective analysis was performed by reviewing the clinicopatholgic records of 40 patients who were diagnosed with DF, and 11 patients who were diagnosed with DFSP, from 1998 to 2012 in Hallym University Medical Center. RESULTS: The ratio of male to female patients in DF and DFSP were 1:2.1 and 1:1.8, respectively. Disease onset ages were 32.6 years and 34.4 years, respectively. The average size was 0.8 cm and 2.0 cm, respectively. The most frequent location was the lower extremity and the trunk, respectively. No symptom was most common subjective symptom in both DF and DFSP. Most of DF presented as brown colored papules and the lesions of DFSP were reported mainly as brown plaques. Histopathologically, the 40 cases of DF were classified as 24 fibrous types, 12 cellular types and 4 aneurysmal types. Of the 11 DFSP, two cases were classified as myxoid type, one case as pigmented lesion (Bednar tumors) and one case as fibrosarcomatous type. Histopathologic findings of the DF showed more significant epidermal hyperplasia, basal hyperpigmentation and collagen trapping, compared to that of the DFSP. The subcutaneous extension and honeycomb pattern were significantly more present in DFSP than in DF. The immunoreactivity of CD34 in DFSP was generally strong and diffuse, in contrast to absent or focal staining seen in DF. CONCLUSION: We conclude that several cilinicopathologic features, including size, location, epidermal and tumoral component, and immunostaining, for CD34 can be used to distinguish DF from DFSP. Further research regarding the characteristics and differences between DF and DFSP should be performed on larger number of cases.
Aneurysm ; Collagen ; Coloring Agents ; Dermatofibrosarcoma ; Factor XIIIa ; Female ; Histiocytoma, Benign Fibrous ; Humans ; Hyperpigmentation ; Hyperplasia ; Lower Extremity ; Male ; Retrospective Studies ; Subcutaneous Fat

PURPOSE: A prospective study was performed to evaluate the efficacies of two different dosages of aspirin(ASA) in treating Kawasaki disease(KD). METHODS: Thirty-nine children with KD were admitted to this hospital from July, 1992 to May, 1993, and were assigned randomly into 2 groups. Group A(medium-dose group, 20 patients) was given 50mg/kg/d(# 4), and group B(high-dose gorup, 19 patients) was given 100mg/kg/d(# 4) of ASA. Intravenous gammaglobulin(2g/kg) was given to all patients. RESULTS: 1) There were no significant differences in ages, sex ratios, durations of fever before treatment, and laboratory findings on admission between two groups. 2) The durations of ASA administration were similar in 2 groups(group A, 10.1+/-2.77 ; group B, 10.6+/-3.37 days ;?p>0.1). 3) The durations of fever after onset of treatment were not different significantly (group A, 2.65+/-3.28 ; group B, 1.74+/-1.52 days ; p>0.1). 4) There were no significant differences in laboratory findings after treatment between two groups, except hemoglobin(Hgb) and ESR examined in the 3 rd week of illness (Hgb: group A (N=15), 10.1+/-1.24 ; group B(n=14), 11.1+/-0.92g/dl ; p<0.05) (ESR: group A(n=14), 47.7+/-13.0 ; group B(n=14), 37.1+/-13.6mm/hr ; p<0.05). 5) Serum concentrations of ASA were examined 3 to 5 days after onset of treatment in 31 patients(group A, 17 ; group B, 14). Mean concentrations before the lst dose of the day were 3.28+/-3.01mg/dl in group A and 12.6+/-6.22mg/dl in group B(p<0.001). Mean concentrations before the 3 rd dose of the day were 3.58+/-2.36mg/dl in group A and 13.7+/-6.32mg/dl in group B(p<0.001). 6) EKG was examined 2 and 4 weeks after onset of illness. There were no abnormalities in EKG except sinus tachycardia in both groups. 7) Echocardiography was done 2 and 4 weeks after onset of illness. Coronary artery dilatation was observed in 40% of group A (8/20) and 31.6% of group B(6/19) at the lst examination (p>0.1), and in 25% of group A(5/20) and 10.5% of group B(2/19) at the 2 nd examination (p>0.1). In long-term follow-up, only 1 patient in each group showed coronary aneurysm respectively. CONCLUSIONS: Although serum concentrations of ASA were different significantly, there were no significant differences in recovery from KD and incidences of coronary artery lesions between two grous. So we think medium-dose aspirin therapy is safe and effective in the treatment of Kawasaki disease.
Aspirin* ; Child ; Coronary Aneurysm ; Coronary Vessels ; Dilatation ; Echocardiography ; Electrocardiography ; Fever ; Follow-Up Studies ; Humans ; Incidence ; Mucocutaneous Lymph Node Syndrome* ; Prospective Studies ; Sex Ratio ; Tachycardia, Sinus

Trichoblastoma is a rare, benign skin tumor of adnexal origin that differentiates toward the hair germ, the embryonic precursor of a hair follicle. Clinically, it presents as a slow growing, solitary, well-circumscribed nodule located predominantly in the head and neck area, with a predilection for the scalp. The trunk, proximal extremities and perianal and genital regions may also be affected. We herein present a case of trichoblastoma which occurred on the trunk as a solitary subcutaneous mass with a central tiny pore in 53-year-old man.
Epidermal Cyst ; Extremities ; Hair ; Hair Follicle ; Head ; Humans ; Middle Aged ; Neck ; Scalp ; Skin

Plantar vein thrombosis is a rare condition, which can cause foot pain when walking. The cause of thrombosis is not clear. We experienced a case of plantar digital vein thrombosis which occurred in the left big toe. The patient was a 35-year-old man who presented with foot pain when during walking since one month ago. There was a solitary skin colored nodule on the left big toe. Skin punch biopsy was performed, and the diagnosis of plantar digital vein thrombosis was made. Plantar digital vein thrombosis is a very rare cause of toe pain. We herein report this interesting case.
Adult ; Biopsy ; Diagnosis ; Foot ; Humans ; Skin ; Thrombosis* ; Toes ; Veins* ; Walking

Chronic mucocutaneous candidiasis is a rare syndrome characterized by persistent and refractory infection of the skin, nail and mucosal tissue by yeasts of the genus Candida. A 70-year-old woman presented with the following skin lesions: ill-defined annular shaped whitish macules on the upper and lower lips accompanying dryness, pain and burning sensation, and yellowish discoloration with onycholysis of the right 4th finger nail. The upper lip lesion showed histopathologic feature of band-like infiltration of lymphocytes in the upper dermis, consistent with lichen planus. But, systemic glucocorticoid was not effective in treating erosive lip lesions. KOH examination and fungal culture of specimens from the upper lip showed hyphal elements and growth of Candida albicans, respectively. Antifungal agent was administered. After the oral medication, skin lesions were improved but there was repeated recurrence. We report a case of chronic mucocutaneous candidiasis misdiagnosed as lichen planus.
Burns ; Candida ; Candida albicans ; Candidiasis, Chronic Mucocutaneous ; Dermis ; Female ; Fingers ; Humans ; Lichen Planus ; Lichens ; Lip ; Lymphocytes ; Mucous Membrane ; Nails ; Onycholysis ; Recurrence ; Sensation ; Skin ; Yeasts

Balloon cell melanoma, an uncommon histopathological variant of malignant melanoma, was first described by Gardner and Vazquez in 1970. This condition is histopathologically characterized by the presence of balloon cells with varying sizes and atypical nuclei. An 84-year-old woman presented with a solitary, dome-shaped, walnut-sized, brownish nodule on the posterior aspect of the left ear with bleeding, having only detected the nodule 2 weeks prior. Histopathologically, the lobulated tumor mass revealed copious melanin pigment and many balloon cells with clear cytoplasm, atypical nuclei, and variable size. Immunohistochemically, the tumor mass showed positive reaction to S-100 protein and HMB 45 staining. We herein report a typical case of balloon cell melanoma, which developed primarily on the skin.
Aged, 80 and over ; Cytoplasm ; Ear ; Female ; Hemorrhage ; Humans ; Melanins ; Melanoma ; S100 Proteins ; Skin

Fluoroscopy-induced chronic radiation dermatitis (FICRD) is a cutaneous disorder that results from prolonged exposure to ionizing radiation during interventional procedures. With the expanded use of interventional procedures, there is increased fluoroscopic exposure. However, diagnosis and treatment of such disorder remain difficult. Herein, we report on a case of FICRD that occurred in the right subscapular area.
Angioplasty, Balloon, Coronary ; Dermatitis ; Radiation, Ionizing