1.Inflammatory Bowel Disease and Lymphoproliferative Disorders.
The Korean Journal of Gastroenterology 2011;58(4):171-177
The risk of lymphoproliferative disorders (LPDs) has been reported to be increased in autoimmune diseases and chronic inflammatory diseases. Similar with other chronic inflammatory diseases such as rheumatoid arthritis, there is a concern about the risk of LPDs in patients with inflammatory bowel disease (IBD). Generally, in IBD patients, the risk of LPDs appears to be similar with or very slightly higher, compared to the general population. The association of therapeutic agents with the risk of LPDs is difficult to evaluate due to multiple other potentially involved factors and co-treatment with other agents. To date, data show that thiopurine is associated with a moderately increased risk of LPDs in patients with IBD. Evidence regarding the risk of LPDs in IBD patients using methotrexate is not sufficient, but the risk of LPDs seems low. The responsibility of anti-TNF-alpha agents on the risk of LPDs is difficult to determine, because most of IBD patients receiving anti-TNF-alpha agents are co-treated with thiopurines. Attention should be given to the high risk of hepatosplenic T-cell lymphoma in young male patients treated with anti-TNF-alpha agents together with thiopurines. The risk and benefit of immunosuppressive therapy for IBD should be carefully evaluated and individualized considering the risk of LPDs.
Anti-Inflammatory Agents/therapeutic use
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Antibodies, Monoclonal/therapeutic use
;
Azathioprine/adverse effects/therapeutic use
;
Humans
;
Immunosuppressive Agents/adverse effects/therapeutic use
;
Inflammatory Bowel Diseases/complications/*drug therapy
;
Lymphoproliferative Disorders/chemically induced/*etiology
;
Methotrexate/therapeutic use
;
Risk Factors
2.The Safety of Thiopurine Treatment in Pregnant Women with Inflammatory Bowel Disease.
The Korean Journal of Gastroenterology 2011;58(1):61-63
No abstract available.
3.Colonic Intussusceptions Caused by a Giant Lipoma.
The Korean Journal of Gastroenterology 2012;60(3):186-189
5.Could Early Anti-Tumor Necrosis Factor Therapy Change the Prognosis of Crohn's Disease?.
Intestinal Research 2014;12(4):263-265
No abstract available.
Crohn Disease*
;
Necrosis*
;
Prognosis*
6.Effect of Combination Pretreatment of Polyethylene Glycol Solution and Magnesium Hydroxide for Colonoscopy.
The Korean Journal of Gastroenterology 2010;55(4):270-272
No abstract available.
Administration, Oral
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*Colonoscopy
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Gastric Lavage/*methods
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Humans
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Magnesium Hydroxide/*administration &dosage
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Polyethylene Glycols/*administration &dosage
8.Successful Transition from Pediatric to Adult Care in Inflammatory Bowel Disease: What is the Key?.
Pediatric Gastroenterology, Hepatology & Nutrition 2019;22(1):28-40
The incidence of pediatric-onset inflammatory bowel disease (IBD) is on the rise, accounting for up to 25% of IBD cases. Pediatric IBD often has extensive bowel involvement with aggressive and rapidly progressing behavior compared to adult IBD. Because IBD has a high morbidity rate and can have a lifelong impact, successful transition from pediatric to adult care is important to maintain the continuity of care. Furthermore, successful transition facilitates appropriate development and psychosocial well-being among patients, as well as comprehensive and harmonious healthcare delivery amongst stakeholders. However, there are various obstacles related to patients, family, providers, and organizations that interfere with successful transition. Successful transition requires a flexible and tailored plan that is made according to the patient's developmental abilities and situation. This plan should be established through periodic interviews with the patient and family and through close collaboration with other care providers. Through a stepwise approach to the transition process, patients' knowledge and self-management skills can be improved. After preparation for the transition is completed and the obstacles are overcome, patients can be gradually moved to adult care. Finally, successful transition can increase patients' adherence to therapy, maintain the appropriate health status, improve patients' self-management, and promote self-reliance among patients.
Adult
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Colitis, Ulcerative
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Continuity of Patient Care
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Cooperative Behavior
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Crohn Disease
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Delivery of Health Care
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Humans
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Incidence
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Inflammatory Bowel Diseases*
;
Self Care
;
Transition to Adult Care*
9.Endoscopic Mucosal Healing as a Treatment Target in Ulcerative Colitis: Does It Have the Same Role in Asian Patients?
Suk-Kyun YANG ; Sang Hyoung PARK ; Byong Duk YE
Gut and Liver 2021;15(6):942-943
no abstract available