Animals ; Enflurane* ; Halothane* ; Isoflurane* ; Rats* ; Relaxation* ; Vasodilator Agents*

Serum creatine kinase (CK) and lactic dehydrogenase (LD) isoenzyme concentrations were studied in 44 patients during orthopedic operations that required the application of a pneumatic tourniquet. CK and LD isoenzymes were measured at preoperation, during tourniquet, and after tourniguet release. In the general anesthesia patients, LD isoenzyme values were not significantly changed during and after touniguet release. CK-BB was more significantly increased (p<0.05) after tourniguet (2.65+/-5. 40IU/l) than at preoperation (0.36+/-1.17IU/l). In the regional block patients, LD isoenzyme values were not significantly changed during and after tourniguet application. CK-BB was more significantly increased (p<0.05) at after tourniguet (0.90+/-1.95IU/l) than at preoperation (0.12+0.48IU/l). But regardleas of tourniguet application time, the values of LD isoenzymes were not significantly changed. CK-BB values were more significantly (p< 0.05) increased after tourniguet release than at preoperation, regardless of tourniguet application time.
Anesthesia, General ; Creatine Kinase ; Humans ; Isoenzymes* ; Orthopedics ; Oxidoreductases ; Tourniquets*

It has been reported that the number of patients with hypertension increases yearly, and this imposes many anesthetic problems during surgery. The etiology of essential hypertension is unknown, but it affects primarily the brain, heart and kidney. The main causes of mortality due to hypertension are cerebrovascular accident, congestive heart failure, myocardial infarction and uremia. For the better anesthetic management of patients wuth hypertension, it is essential to clearly understand the pathophysiologic changes and hemodynamic patterns of hypertension. Because of the controversy regarding the appropriateness of preoperative treatment of hypertension, this article will evaluate the effect of preoperative antihypertensive medication on blood pressure during anesthesia of hypertensive patients. Patients with hypertension were divided into two groups, one group consisting of ll patients, who received antihypertensive medication in the preoperative period, and the other group, consisting of 11 patients, who did not received antihypertensive medication for the control of high blood pressure preoperatively. Changes of arterial blood pressure during anesthesia were analyzed, and data were compared between the two groups. The results were as follows: The patient who receivecd antihypertensisve medication for preoperative anesthetic management showed the same arterial blood pressure fluctuation during general anesthesia, as the patients who had not received antihypertensive medication (p < 0. 05). In the treated group, the blood pressure and heart rate changes during preinduction and intubation showed significant increase compared to the ward's values, but did not show a significant increase during operation annd recovery. In the nontreated group, the results showed similar changes with the treated group. It may be suggested from the above observation that the preoperative control of hypertension dose not affect the changes of blood pressure in the perioperative period.
Anesthesia* ; Anesthesia, General ; Arterial Pressure ; Blood Pressure* ; Brain ; Heart Failure ; Heart Rate* ; Heart* ; Hemodynamics ; Humans ; Hypertension ; Intubation ; Kidney ; Mortality ; Myocardial Infarction ; Perioperative Period ; Preoperative Period ; Stroke ; Uremia

The aim of this investigation was to determine whether epidural analgesia has any effect on the uterine activity. Uterine activity was checked by an intermal tocometer and calculated in uterine activity units (UAU) which were expressed as Montevideo units. Twenty two gravidas who had the term pregnancy in labor without any obstertical complications were selected and epidural analgesia was performed in 17 of these patients. Plain lidocaine was used in 10 of them, lidocaine mixed with epinephrine (200,000:1) was used in another 7 gravidas and 5 gravidas were chosen as a control group. The results were as follows: The uterine actvity of the continuous epidural anesthesia group did not differ from that of the control group. The uterine activity changes were not statistically significant between the plain Iidocaine group and the epinephrine mixed group.
Analgesia, Epidural ; Anesthesia, Epidural* ; Epinephrine ; Humans ; Lidocaine ; Pregnancy ; Uterine Contraction*

Glomus tumors are a rare, benign neoplasm and 75% exist in the subungual region. Extradigital glomus tumors are much more difficult to diagnose because of their atypical location and symptoms. Furthermore, if their symptoms are similar to neuropathic pain, the patient can suffer from misdirected treatment due to misdiagnosis. It is essential to perform careful evaluation of the lesion itself in order to reduce misdiagnosis. Ultrasonography is a useful, non-invasive method that can be easily performed in the pain clinic for local evaluation and diagnosis. We report a case of misdiagnosed glomus tumor in the thigh which was properly diagnosed after ultrasonography.
Diagnosis ; Diagnostic Errors ; Glomus Tumor* ; Humans ; Neuralgia ; Pain Clinics ; Thigh* ; Ultrasonography