Acute alcoholic myopathy presented with paraparesis, myoglobinuria. And acute renal failure is an uncommon complication of alcoholism. A 34-year-old man had been a heavy alcohol drinker for a year, complained of sudden lower extremity weal; ness and swelling after heavy drinking. On examination, lower extremity was swollen and unable to move. Laboratory data showed markedly elevated GOT, LDH, CK, and myoglobinuria. Initial electrodiagnostic study was indefinite for diagnosis of myopathy and biopsy of the quadriceps muscle showed slight increased eosinophilia of sarcoplasm. But in followup study, myopathic findings and degeneration becarne apparent in electromyography and blopsy.
Acute Kidney Injury ; Adult ; Alcoholics* ; Alcoholism ; Biopsy ; Diagnosis ; Drinking ; Electromyography ; Eosinophilia ; Follow-Up Studies ; Humans ; Lower Extremity ; Muscular Diseases* ; Myoglobinuria ; Paraparesis* ; Quadriceps Muscle ; Renal Insufficiency*

Autoimmune neutropenia is characterized by severe neutropenia with cell-bound neutrophil antibodies or circulating antibodies for neutrophils. Diagnosis of disease is made of the basis of the presence of antibodies for neutrophil. Corticosteroid or rhG-CSF have been reported to be effective in some patients. Recently we experienced one case of autoimmune neutropenia patient who was admitted to our hospital in 1997 because of stomach cancer and degenerative joint disease. She had severe neutropenia without underlying autoimmune disease. And cell-bound neutrophil antibodies were detected by indirect immunofluorescence test. Treatments with rhG-CSF and steroid result in transient improvement of neutropenia and subtotal gastrectomy was done successfully. We herein report one case of autoimmune neutro- penia patient, to our best knowledge, the first report in Korea, with a brief review of literature.
Antibodies ; Autoimmune Diseases ; Diagnosis ; Fluorescent Antibody Technique, Indirect ; Gastrectomy ; Humans ; Joint Diseases ; Korea ; Neutropenia* ; Neutrophils ; Stomach Neoplasms

No abstract available.
Craniocerebral Trauma* ; Head* ; Humans ; Tomography, Emission-Computed, Single-Photon*