1.An analysis of contents of inpatients in department of family medicine.
Hae Won LEE ; Ho Yeon SONG ; Ji Hyeon CHO ; Dong Young CHO ; Byeong Yeon YOO
Journal of the Korean Academy of Family Medicine 1993;14(12):804-813
No abstract available.
Humans
;
Inpatients*
2.Effects of aluminum on choline uptake and activities of choline acetyltransferase and acetylcholinesterase in rat brain.
Jong Inn WOO ; Byeong Kil YEON ; Yoo Hun SUH ; Chan Woong PARK ; Chung Kyoon LEE
Journal of Korean Neuropsychiatric Association 1991;30(6):961-973
No abstract available.
Acetylcholinesterase*
;
Aluminum*
;
Animals
;
Brain*
;
Choline O-Acetyltransferase*
;
Choline*
;
Rats*
3.An Experimental Study on the Immune Complex Induced Chronic Arthritis in Rabbits: Reference to Macrophophages and M-type Cells of Synovium
Tae Seung KIM ; Byeong Yeon SEONG ; In joon CHOI ; Yoo Bock LEE
The Journal of the Korean Orthopaedic Association 1984;19(2):219-232
No abstract available in English.
Antigen-Antibody Complex
;
Arthritis
;
Rabbits
;
Synovial Membrane
4.Marginal and internal fit of nano-composite CAD/CAM restorations.
So Hyun PARK ; Yeon Jee YOO ; Yoo Jin SHIN ; Byeong Hoon CHO ; Seung Ho BAEK
Restorative Dentistry & Endodontics 2016;41(1):37-43
OBJECTIVES: The purpose of this study was to compare the marginal and internal fit of nano-composite CAD-CAM restorations. MATERIALS AND METHODS: A full veneer crown and an mesio-occluso-distal (MOD) inlay cavity, which were prepared on extracted human molars, were used as templates of epoxy resin replicas. The prepared teeth were scanned and CAD-CAM restorations were milled using Lava Ultimate (LU) and experimental nano-composite CAD/CAM blocks (EB) under the same milling parameters. To assess the marginal and internal fit, the restorations were cemented to replicas and were embedded in an acrylic mold for sectioning at 0.5 mm intervals. The measured gap data were pooled according to the block types and measuring points for statistical analysis. RESULTS: Both the block type and measuring point significantly affected gap values, and their interaction was significant (p = 0.000). In crowns and inlays made from the two blocks, gap values were significantly larger in the occlusal area than in the axial area, while gap values in the marginal area were smallest (p < 0.001). Among the blocks, the restorations milled from EB had a significantly larger gap at all measuring points than those milled from LU (p = 0.000). CONCLUSIONS: The marginal and internal gaps of the two nano-composite CAD/CAM blocks differed according to the measuring points. Among the internal area of the two nano-composite CAD/CAM restorations, occlusal gap data were significantly larger than axial gap data. The EB crowns and inlays had significantly larger gaps than LU restorations.
Computer-Aided Design
;
Crowns
;
Fungi
;
Humans
;
Inlays
;
Molar
;
Tooth
5.Marginal and internal fit of nano-composite CAD/CAM restorations.
So Hyun PARK ; Yeon Jee YOO ; Yoo Jin SHIN ; Byeong Hoon CHO ; Seung Ho BAEK
Restorative Dentistry & Endodontics 2016;41(1):37-43
OBJECTIVES: The purpose of this study was to compare the marginal and internal fit of nano-composite CAD-CAM restorations. MATERIALS AND METHODS: A full veneer crown and an mesio-occluso-distal (MOD) inlay cavity, which were prepared on extracted human molars, were used as templates of epoxy resin replicas. The prepared teeth were scanned and CAD-CAM restorations were milled using Lava Ultimate (LU) and experimental nano-composite CAD/CAM blocks (EB) under the same milling parameters. To assess the marginal and internal fit, the restorations were cemented to replicas and were embedded in an acrylic mold for sectioning at 0.5 mm intervals. The measured gap data were pooled according to the block types and measuring points for statistical analysis. RESULTS: Both the block type and measuring point significantly affected gap values, and their interaction was significant (p = 0.000). In crowns and inlays made from the two blocks, gap values were significantly larger in the occlusal area than in the axial area, while gap values in the marginal area were smallest (p < 0.001). Among the blocks, the restorations milled from EB had a significantly larger gap at all measuring points than those milled from LU (p = 0.000). CONCLUSIONS: The marginal and internal gaps of the two nano-composite CAD/CAM blocks differed according to the measuring points. Among the internal area of the two nano-composite CAD/CAM restorations, occlusal gap data were significantly larger than axial gap data. The EB crowns and inlays had significantly larger gaps than LU restorations.
Computer-Aided Design
;
Crowns
;
Fungi
;
Humans
;
Inlays
;
Molar
;
Tooth
6.Direction of the J-Tip of the Guidewire to Decrease the Malposition Rate of an Internal Jugular Vein Catheter.
Byeong Jun AHN ; Sung Uk CHO ; Won Joon JEONG ; Yeon Ho YOU ; Seung RYU ; Jin Woong LEE ; In Sool YOO ; Yong Chul CHO
Korean Journal of Critical Care Medicine 2015;30(4):280-285
BACKGROUND: We hypothesized that the direction of the J-tip of the guidewire during insertion into the internal jugular vein (IJV) might determine its ultimate location. METHODS: In this study, 300 patients between the ages of 18 and 99 years who required central venous catheterization via IJV in the emergency department enrolled for randomization. IVJ catheterization was successful in 285 of 300 patients. An independent operator randomly prefixed the direction of the J-tip of the guidewire to one of three directions. Based on the direction of the J-tip, patients were allocated into three groups: the J-tip medial-directed group (Group A), the lateral-directed group (Group B), or the downward-directed group (Group C). Postoperative chest radiography was performed on all patients in order to visualize the location of the catheter tip. A catheter is considered malpositioned if it is not located in the superior vena cava or right atrium. RESULTS: Of the total malpositioned catheter tips (8 of 285; 2.8%), the majority (5 of 8; 62.5%) entered the contralateral subclavian vein, 2 (25.0%) were complicated by looping, and 1 (12.5%) entered the ipsilateral subclavian vein. According to the direction of the J-tip of the guidewire, the incidence of malpositioning of the catheter tip was 4 of 92 in Group A (4.3%), 4 of 96 in Group B (4.2%), and there were no malpositions in Group C. There were no significant differences among the three groups (p = 0.114). CONCLUSIONS: The direction of the J-tip of the guidewire had no statistically significant effect on incidence of malpositioned tips.
Catheterization
;
Catheterization, Central Venous
;
Catheters*
;
Central Venous Catheters
;
Emergency Service, Hospital
;
Heart Atria
;
Humans
;
Incidence
;
Jugular Veins*
;
Radiography
;
Random Allocation
;
Subclavian Vein
;
Thorax
;
Vena Cava, Superior
7.Two Cases of Mucinous Ductal Ectasia of the Pancreas which Showed Characteristic Pancreatoscopic Findings.
Young Il MIN ; Sung Koo LEE ; Myung Hwan KIM ; Byeong Moo YOO ; Seung Jae MYUNG ; Hyo Sook PARK ; Sung Ae JUNG ; Dong Whn SEO ; Yeon Suk KIM ; Hae Kyung KIM ; Kyung Yub GONG
Korean Journal of Gastrointestinal Endoscopy 1996;16(4):674-679
We report two cases of mucinous ductal ectasia of the pancreas which showed characteristic pancreatoscopic findings. They also showed characteristic duodenoscopic findings such as patulous ampullary orifice and mucus leakage from the papilla, and underlying pathology was hyperplasia in one case and adenoma in the other case, The insertions of pancreatoscope into the main pancreatic duct were easy without previous sphincterotomy and whitish frog egg-like mucosa was noted in one case and finger-like papillary projection was noted in the other case.
Adenoma
;
Dilatation, Pathologic*
;
Hyperplasia
;
Mucins*
;
Mucous Membrane
;
Mucus
;
Pancreas*
;
Pancreatic Ducts
;
Pathology
8.Diagnostic mutational analysis of MECP2 in Korean patients with Rett syndrome.
In Joo KIM ; Yeon Joo KIM ; Byeong Hee SON ; Sang Ook NAM ; Hoon Chul KANG ; Heung Dong KIM ; Mi Ae YOO ; Ook Hwan CHOI ; Cheol Min KIM
Experimental & Molecular Medicine 2006;38(2):119-125
Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder affecting 1 per 10,000- 15,000 female births worldwide. The disease-causing gene has been identified as MECP2 (methyl- CpG-binding protein 2). In this study, we performed diagnostic mutational analysis of the MECP2 gene in RTT patients. Four exons and a putative promoter of the MECP2 gene were analyzed from the peripheral blood of 43 Korean patients with Rett syndrome by PCR-RFLP and direct sequencing. Mutations were detected in the MECP2 gene in approximately 60.5% of patients (26 cases/43 cases). The mutations consisted of 14 different types, including 9 missense mutations, 4 nonsense mutations and 1 frameshift mutation. Of these, three mutations (G161E, T311M, p385fsX409) were newly identified and were determined to be disease-causing mutations by PCR- RFLP and direct sequencing analysis. Most of the mutations were located within MBD (42.3%) and TRD (50%). T158M, R270X, and R306C mutations were identified at a high frequency. Additionally, an intronic SNP (IVS3+23C>G) was newly identified in three of the patients. IVS3+23C>G may be a disease-related and Korea-specific SNP for RTT. L100V and A201V are apparently disease-causing mutations in Korean RTT, contrary to previous studies. Disease-causing mutations and polymorphisms are important tools for diagnosing RTT in Koreans. The experimental procedures used in this study should be considered for clinical molecular biologic diagnosis.
Rett Syndrome/diagnosis/*genetics
;
Polymorphism, Single Nucleotide
;
Polymorphism, Restriction Fragment Length
;
Polymerase Chain Reaction
;
*Mutation
;
Molecular Sequence Data
;
Methyl-CpG-Binding Protein 2/*genetics
;
Male
;
Korea
;
Humans
;
Female
;
DNA Mutational Analysis
;
Base Sequence
9.Prevalence and Risk Factors of Dementia and Depression in the Elderly.
Guk Hee SUH ; Jang Kyu KIM ; Byeong Kil YEON ; Sue Kyung PARK ; Keun Young YOO ; Byung Kook YANG ; Yong Sik KIM ; Maeng Je CHO
Journal of Korean Neuropsychiatric Association 2000;39(5):809-824
An epidemiological survey was conducted to estimate the prevalence of and identify the risk factors of dementia and depression in the elderly between December 1997 and August 1998 in Yonchon County, Korea. A total of 1,037 elderly aged 65 years and over underwent a two phase diagnositc procedure. Multiple stage, random cluster sampling method was used to select the subjects. Response rate was 85.4%. For the 1st stage screening survey, the Korean Psychogeriatric Assessment Scale was used as a primary screening tool, which had already been standardized in Korea, and functioning and social support were assessed by ADL, IADL and APGAR. At the 2nd stage, diagnoses were confirmed according to the DSM-III-R. And several other scales were used as supporting information for differential diagnoses and for evaluating severity. 1) Age-sex adjusted prevalence(%)[95% C.I.] of dementia was 6.83[6.12-7.54](male 6.34[5.29-7.40]female 7.09[6.14-8.04]). Prevalence of the dementia of the Alzheimer's type was 4.17[3.61-4.74](male 2.42[1.76-3.08], female 5.31[4.48-6.14]) and that of the vascular dementia was 2.38 [1.95-2.81](male 3.46[2.67-4.25], female 1.63[1.16-2.10]). 2) Age-sex adjusted prevalence(%)[95% C.I.] of depressive disorder was 10.99 [10.11-11.87] (male 7.59[6.44-8.73], female 13.46[12.20-14.73]). Among depressive disorders, prevalence(%) [95% C.I.] of major depressive disorder was 7.50[6.76-8.26](male 4.42[3.54-5.31], female 9.78 [8.68-10.88]), that of dysthymic disorder was 2.02[1.62-2.42](male 1.37[0.86-1.87], female 2.46 [1.88-3.03]) and that of depressive disorder NOS was 1.49[1.15-1.83](male 1.85[1.47-2.23], female 1.28[0.96-1.60]). 3) Five statistically significant risk factors of the dementia of the Alzheimer's type were identified: age over 85(O.R.=10.27), illiteracy(O.R.=4.01), alcohol abuse(O.R.=2.98), smoking[0
Activities of Daily Living
;
Aged*
;
Dementia*
;
Dementia, Vascular
;
Depression*
;
Depressive Disorder
;
Depressive Disorder, Major
;
Diagnosis
;
Diagnosis, Differential
;
Dysthymic Disorder
;
Literacy
;
Female
;
Humans
;
Korea
;
Mass Screening
;
Prevalence*
;
Risk Factors*
;
Smoke
;
Smoking
;
Weights and Measures
10.Direction of the J-Tip of the Guidewire to Decrease the Malposition Rate of an Internal Jugular Vein Catheter
Byeong Jun AHN ; Sung Uk CHO ; Won Joon JEONG ; Yeon Ho YOU ; Seung RYU ; Jin Woong LEE ; In Sool YOO ; Yong Chul CHO
The Korean Journal of Critical Care Medicine 2015;30(4):280-285
BACKGROUND: We hypothesized that the direction of the J-tip of the guidewire during insertion into the internal jugular vein (IJV) might determine its ultimate location. METHODS: In this study, 300 patients between the ages of 18 and 99 years who required central venous catheterization via IJV in the emergency department enrolled for randomization. IVJ catheterization was successful in 285 of 300 patients. An independent operator randomly prefixed the direction of the J-tip of the guidewire to one of three directions. Based on the direction of the J-tip, patients were allocated into three groups: the J-tip medial-directed group (Group A), the lateral-directed group (Group B), or the downward-directed group (Group C). Postoperative chest radiography was performed on all patients in order to visualize the location of the catheter tip. A catheter is considered malpositioned if it is not located in the superior vena cava or right atrium. RESULTS: Of the total malpositioned catheter tips (8 of 285; 2.8%), the majority (5 of 8; 62.5%) entered the contralateral subclavian vein, 2 (25.0%) were complicated by looping, and 1 (12.5%) entered the ipsilateral subclavian vein. According to the direction of the J-tip of the guidewire, the incidence of malpositioning of the catheter tip was 4 of 92 in Group A (4.3%), 4 of 96 in Group B (4.2%), and there were no malpositions in Group C. There were no significant differences among the three groups (p = 0.114). CONCLUSIONS: The direction of the J-tip of the guidewire had no statistically significant effect on incidence of malpositioned tips.
Catheterization
;
Catheterization, Central Venous
;
Catheters
;
Central Venous Catheters
;
Emergency Service, Hospital
;
Heart Atria
;
Humans
;
Incidence
;
Jugular Veins
;
Radiography
;
Random Allocation
;
Subclavian Vein
;
Thorax
;
Vena Cava, Superior