No abstract available.
Aged* ; Humans ; Long-Term Care*

No abstract available.
Dementia*

Disturbances in memory are the most common problem in patients with an organic mental syndrome. Other patients with significant psychiatric disorder also often have memory. So it is very important in the clinical practice of psychiatry to understand the biological and neurocognitive mechanisms of memory proessing, and to develop the assessment tools with which memory function can be evaluated reliably and validly. Moreover, memory researches provide an important viewpoint from which we can understand the pathophysiological mechanisms of major neuropsychiatric illnesses. This article focuses on our understanding of memory function in clinical and neurobiological aspects. The relevant material will be presented in four pats : 1) terminologies needed in defining major stages of various types of memory processing : 2) neurochemical and neuroanatomical basis of memory processing : 3) brief bedside screening and more comprehensive neuropsychological tests for the evaluation of memory function : 4) the characteristics of memory dysfunction in several major psychiatric illnesses.
Humans ; Mass Screening ; Memory* ; Neuropsychological Tests ; Neuropsychology

No abstract available.

Fractures of the pateila Is one of the most important subjects considering the increasing number of such patients Much has been written concerning these fractures during last thirty years or more. In this series, we reviewed 78 fractures of the patella, we could follow up from January 1964 to December 1978. Most of the fractures occurred in man, and occurred In third to forth decades. Traffic accident was the most common cause. Twelve cases were open fractures and most of the fractures were comminuted or transverse type. we treated these 78 cases as followings: 1. Total excision, 8 2. Partial excision, 19 3. Open raduction and Internal flxation, 21 (of these, Circumferential wire loop flxation, 13; Magnuson wire loop fixation, 3; Tension band wiring, 5) 4. Conservative treatment, 30. Average follow-up period was 26.6 weeks and average flexion range of knee at the end of the period was 118.2. The end results of Tension band wiring was much better than those of other methods. It Is considered that the range of motion of the knee jolnt after treatment was Influenced by immobilization period. The shorter the period, the better the result.
Accidents, Traffic ; Clinical Study ; Follow-Up Studies ; Fractures, Open ; Humans ; Immobilization ; Knee ; Patella ; Range of Motion, Articular

No abstract available.
Animals* ; Brain* ; Hypothermia* ; In Situ Nick-End Labeling* ; Models, Animal*

The decline of cognitive functions uses to follow the increase in incidence of various organic mental disorders and systemic diseases, and administration of drugs with increasing age. The assessments of cognitive functions are needed to discriminate normal aging from other cognitive disorders and to differentiate the organic mental disorders. We have to be cautious to interpret the test results of elderly patients who are easily fatigue and frequently have sensory disturbances. There are two basic approaches to assess cognitive function of the elderly patients. One is to use standardized test batteries and another is to use several tests that are relevant to diagnostic purposes. Many assessment tools of cognitive functions have been developed and used clinically but there are a few available standardized test in Korea. It is eagerly needed to develope standardized tests that are pertinent our culture.
Aged* ; Aging ; Neurocognitive Disorders ; Fatigue ; Humans ; Incidence ; Korea

No abstract available.
Acetylcholinesterase* ; Aluminum* ; Animals ; Brain* ; Choline O-Acetyltransferase* ; Choline* ; Rats*

As Alzheimer's disease is the most common cause of dementia in older people, many efforts for accurate and reliable clinical diagnoses have been made all over the world. Generally diagnostic process of Alzheimer's disease is constituted with two steps : 1) to determine whether a patient is actually demented, 2) to determine whether the dementia actually caused by Alzheimer's disease. Newly developed diagnostic criteria, such as diagnostic criteria of the National Institute on Aging-Alzheimer's Association improve their specificity to diagnose Alzheimer's disease. We need Korean specific guideline for diagnosing Alzheimer's disease compatible in Korean clinical situation.
Alzheimer Disease ; Dementia ; Humans ; Sensitivity and Specificity

It has been widely known that the elderly suffer very mild cognitive impairment including memory function that cannot satisfy the criteria of dementia. Koivisti and Hannien et al reported that the prevalences of age-associated memory impairment and age-associated cognitive decline were 38.6% and 26.6%, respectively. The prevalence rate of male was more than that of female and the prevalence rate was increased in younger elderly. The risk factors of age-related cognitive decline were age and myocardiac infarction whereas education and smoking decreased the risk of age-related cognitive decline. The small portion of age-associated memory impairment progressed toward dementia but the most of them were nonprogressive. The probability of progression toward dementia could be predicted by detailed neurocognitive function test. The further epidemiologic studies will reveal the nature of age-associated memory impairment.
Aged ; Dementia ; Education ; Epidemiologic Studies ; Epidemiology* ; Female ; Humans ; Infarction ; Male ; Memory* ; Mild Cognitive Impairment ; Prevalence ; Risk Factors ; Smoke ; Smoking