No abstract available.
Animals ; Rats*

Although many different attempts have been made to reduce adhesions after tendon surgery, this complicated problem continues to be foremost among factors compromising tendon surgery and repair. The results of the finest tendon surgery and repair are frequently compromised by adhesions that restrict motion, decrease function and often lead to permanent deformation. Many substances and materials have been introduced into the area around primary flexor tendon repairs in an effort to prevent or diminish the adhesion formation. Various biochemical agents including antihistamines, anaboilic agents, lathyrogenic drug, betaamino-propionitrile and steroids, have been investigated and material such as nylon, cellophane, polyethylene film and silastic have been used to form pseudosheath. However the results with all of these method have been disappointing. Recently, interest has grown in a mucopolysaccharide found in synovial fluid hyaluronic acid. Synovial fluid normally contains a concentration of 2-3 mg/ml of hyaluronic acid. Preliminary investigations suggest that hyaluronic acid placed between the tendon and its sheath promote tendon healing and decrease adhesion formation. With this in mind, the present study was designed to examine the effect of hyaluronic acid on injured chicken flexor tendon healing and to determine the quantity and quality for adhesions in hyaluronic acid treated chicken compared to control. The stereomicroangiographic technique has enabled us to study the vascular process inside the tendon and surrounding tissues after injury of the tendon. For the study, the deep flexor tendon of the third toe of adult chicken with initial weight of about 2kg was used. Animals were divided into three groups and treated with different levels of hyaluronic acid. After 1,3,7,21,35 and 42 days postoperation, the animals were sacrificed and specimen were prepared. Obtained specimen were examined macroscopically and microscopically. At 1,3,5, and 7 weeks postoperation, microangiographic study were done and examind specimen by stereomicroscope. The results were as follows: 1. Though both the treated and control groups showed adhesion, hyaluronic acid treated tendon showed less adhesion tissue and better sliding properties as compared to the controls. 2. During the first week after operation, microangiographic studies showed failure of filling of all the vessels within the injured tendon. At 3 weeks highly vascular adhesions which extended throughout the injured site were observed. After then, the amount of vascularity decreased. 3. There were no difference microscopically between hyaluronic acid treated and control group at first week. After one week hyaluronic acid treated group showed less granulation tissue and less formation of collagen fibers. 4. There were no difference of healing process between hyaluronic acid treated and control group. From this results, it is suggested that hyaluronic acid is effective in reducing the adhesions after the tendon surgery.
Adult ; Animals ; Cellophane ; Chickens ; Collagen ; Granulation Tissue ; Histamine Antagonists ; Humans ; Hyaluronic Acid ; Methods ; Nylons ; Polyethylene ; Steroids ; Synovial Fluid ; Tendons ; Toes

No abstract available.
Eyelids* ; Transplants*

No abstract available in English.
Clinical Study ; Extremities ; Fractures, Spontaneous

Immunoblot analysis utilizing bovine sera from naturally or experimentally infected with Theileria sergenti were used to determine the immunodominant polypeptides of T. sergenti (Korea isolate).The previously recognized major bands, 18 kDa, 29 kDa, 34 kDa, and 45 kDa, were excised after electrophoresis and trasferred to PVDF membrane. The individual bands were sequenced. The 34 kDa polypeptide which was the most antigenic and immunogenic peptide was observed in the Western blot. However, Chou-Fasman prediction sites (antiginic site) for antigen determinants of the 45 kDa,34 kDa, 29 kDa and 18 kDa polypeptide were 6, 4, 2 and 0, respectively. However, the 45 kDa polypeptide showed no reaction with anti-T. sergenti hyperimmune serum.
parasitology-protozoa ; Theileria sergenti ; amino acid sequence ; synthetic peptide ; predicted antigenic value ; amino acid

No abstract available.
Angiomyolipoma* ; Lymph Nodes*

The orbitozygomatic area occupies a key anatomic position in midface, is prone to injury, and plays a prominent role in facial aesthetics. So the facial appearance including orbital shape can be altered by complications of orbitozygomatic fractures. Most possible initial complications include blindness, hyphema, retinal detatchment, and paralysis or entrapment of extraocular muscles. Long term sequelaes include infraorbital nerve dysfunction, loss of malar projection, enophthalmos, and dystopia. Accurate anatomic reduction and rigid fixation is essential for management of orbitozygomatic fractures to minimize those late sequelaes. Conventional fixation devices to fix displaced fracture of facial bone are interosseous wire and miniplate. But interosseous wirings are unstable for primary bone healing and time consuming. Miniplates have great deal in rigid fixation but their high profile and palpability are the main complaints in many patients, especially in orbital rim area. In this article, we reviewed the 30 cases of zygomamaxilla complex fractures with orbital rim fracture fixed with microplates, and discussed the stability of microplate and superiorities in final aesthetics result. The use of microplates in these area permits enough stability of fracture segment with ease of procedures and superiorities in final results without any palpability.
Blindness ; Enophthalmos ; Esthetics ; Facial Bones ; Humans ; Hyphema ; Muscles ; Orbit* ; Paralysis ; Retinaldehyde

OBJECT: Pre-ALL is a very rare preteukemic state, which percedes acute lymphocytic leukemia, while MDS(pre-ANLL), usually the well-known type of preleukemic state, precedes acute non-lymphocytic leukemia. Initially it shows transient pancytopenia without any evidence of leukemia in bone marrow findings, followed by acute lymphocytic leukemia after recovery from pancytopenia of a short period within weeks or months. We report a case with pre-ALL in childhood. CASE: A 15-month-old male baby was admitted with the complaints of fever and cough for 5 days and pallor for 2 weeks prior to admission. On admission, CBC showed pancytopenia without any evidence of leukemia, which was recovered spontaneously in a short period, and then was followed by acute lymphocytic leukemia of CALLA negative, early pre-B cell type. During antileukemic chemotherapy, he had suffered from severe bacterial infections and was finally died of sepsis 8 months after first admission. CONCLUSION: We report a case of pre-ALL in childhood, which was preceded by CALLA negative, early pre-B cell ALL, with a review of the literatures, briefly.
Bacterial Infections ; Bone Marrow ; Cough ; Drug Therapy ; Fever ; Humans ; Infant ; Leukemia ; Male ; Pallor ; Pancytopenia ; Precursor Cell Lymphoblastic Leukemia-Lymphoma* ; Precursor Cells, B-Lymphoid ; Sepsis

No abstract available.
Heart* ; Thoracic Surgery*

No abstract available.
Abscess*