Background: Our research team aimed at determining the prevalence of depression and mutual interaction of other diseases among elderly in today’s changing period of morbidity of population due to social and economic transition.Goal: To determine the correlation between depression and other diseases among elderlyObjectives:1. To determine the prevalence of depression among elderly2. To find out the correlation between depression and other diseasesMaterials and method: The research was carried out by cross sectional method. In the research was involved 1207 elderly, who are retired, of which 60 and over for male and 55 and over for female from one cluster of each economic and geographic regions of Mongolia. The depression was evaluated by using Geriatric Depression Scale.Results: In the research was involved 392 (32.5 percent) men, 675 (67.5 percent) women and their mean age was 68.1±8.1 (68.9±6.5 in male and 65.7±8.5 in female) from 4 economic and geographic regions of Mongolia. Among survey involved elderly, 16.5 (199) percent of them were found to have depression. Out of survey involved depressed elderly, 27.6 percent were male and 72.3 percent female. The mean age of depressed elderly was 67.9, in which 67.1 in women and 70.2 in men. Due to depression status among survey involved elderly, the share of elderly, who inclined to affect by depression was 158 (13.1%). Furthermore, 169 (14%) of them were affected by slight depression, while 30 (2.5%) of them were with severe depression.Among survey involved elderly, 24.5 percent of elderly with anxiety were inclined to be affected by depression and 29.2 percent of them were with mildly depression. However, 5.6 percent of elderly with severely level of anxiety were affected by severe depression. It was not found severe depressed elderly among elderly, who did not have anxiety. The depression of elderly and their morbidity has direct correlation. Elderly depression and anxiety has direct medium correlation.Conclusions:1. The prevalence of depression among Mongolian elderly refers 16.5 percent.2. Depression among Mongolian elderly has direct correlation to some investigated somatic diseases.

Background: In our country, the survey on mental condition of Mongolian elderly, in particularly on assessing the cognitive status has not provided yet. Goal: To determine the cognitive status of elderly and find out some factors which affect on it. Objectives:1. Determine the cognitive ability of Mongolian elderly2. Find out some factors which affect the cognitive ability of elderlyMaterials and Methods: In this cross sectional study, we had chosen randomizily 1 cluster from each 4 economic and geographic regions of Mongolia and Ulaanbaatar city, and totally comprised of 1207 elderly, of which 60 and over for male and 55 and over for female. The cognitive status of survey involved elderly was evaluated by mini mental examination test (MMET).Results: The mean age of survey involved elderly was 68.1±8.1 (68.9±6.5 in male and 65.7±8.5 in female). While 60.3(728) percent of elderly people were normal, 39.7(479) percent of them estimated to have cognitive decline. Out of elderly with cognitive decline, 59.5 percent had slight cognitive impairment, 35.1 percent moderate cognitive impairment and rest 5.4 percent had severe cognitive impairment. The cognitive impairment predominantly revealed in female and prevailed more in elderly who live in countryside compared to elderly who live in the city (P<0.001). The cognitive impairment was related to educational background of elderly who had cognitive decline. Along the decline of education estimated higher level of cognitive impairment, as well as 47.5 percent of male and 53.8 percent of female, who had lower education, shared most percentage of cognitive impairment, compared to other educational levels.The cognitive impairment is directly correlated to decline of Activity of daily living and Instrumental activity of daily living of elderly (p<0,0001).Conclusions:1. The decline of cognitive status of elderly is correlated to gender. The educational background, income and family are related to their cognitive impairment.2. Activity of daily living and Instrumental activity of daily living have direct correlation to cognitive impairment of elderly.

Introduction: Findings of study on disability types among Mongolian population confirm that 16631 (15.4) refers to visual impairment, speech and language disability 5999 (5.6), hard of hearing 12633 (11.7), mobility impairment 31265 (28.9), intellectual impairment 20898 (19.3) and other disabilities 20645 (19.1). There is no other study which assessed disability prevalence and some determinant factors which lead to disability and health status among older (ages women 55+, men 60+) disabled Mongolians. Goal: To assess the reason and type among disabled older Mongolians Materials and methods: This study was conducted on a random sample of disabled elderly people residing in Ulaanbaatar, Mongolia. Study is based on questionnaire and interview to indicate some health conditions. We used formal methods to assess activities of daily living and instrumental activities of daily living of disabled older people.Result: The sample represented 46.2% of men and 53.8% women in respondents. Median age of respondents was 75.2±10.5 (men 74.2±8.7, women 76.2±11.8). While 72.3% of respondents did physical work, 25.4% respondents did intellectual work and only 2.3% respondents had physical-intellectual work. According to the types of disability, 36.7% of respondents had mobility impairment, 16.7% of elder people had visual disability and 12.2% of respondents had hearing impairment. While 94.6% respondents had acquired disability, 4.6% respondents had congenital disability. In terms of activities of daily living, 76.2% of respondents had difficulty in bathing independently, 38.5% with dressing, and 62.3% had moving limitations at home.Conclusions:1. Mobility disability is higher (36.7%) than other types of disability among disabled older people.2. About 76.2% respondents had disability because of some diseases, about 8.5% about 8.5% from occupational disease, about 3.1% respondents from industrial injuries and about 11.5% respondents because of home injuries.3. Disability with activities of daily living is about 48% among disabled older people and the highest disabled daily activity is bathing, about 76.2%. Disability with instrumental activities of daily living is about 66% in disabled older people and the highest disabled instrumental activity is about 90%, is walking in long distance.4. According to this conclusion, disabled older people will greatly increase to demand health and social care assistance.

Introduction: The issue of meeting need of rehabilitation care service required to elders is one of determinants which influences in enabling quality of life of elderly people. In our country, we lack of survey on determining current need of long term care and one of its form rehabilitation care service for the elderly, so it became the background of the research. Goal: Reveal some needs of rehabilitation care service through determining the Activities of daily living and Instrumental Activities of daily living of Mongolian elderly people Materials and Method: The research was carried out by cross sectional method. In the research was involved 1207 elderly, who are retired, of which 60 and over for male and 55 and over for female from one cluster of each economic and geographic regions of Mongolia. The research was conducted by using ADL and IADL tests as well as questionnaire to determine the needs of rehabilitation care service. Results: Out of survey involved 1207 elderly, 32.5 percent (392) referred to men, 67.5 percent (815) to women, and their mean age was 68.1±8.1 (68.9±6.5 in male and 65.7±8.5 in female). While 473 elderly were from Ulaanbaatar city, 734 of them were from 4 regions of countryside. Among survey involved elderly, the mean of ADL ability was 87.4 percent, of which, the following abilities were better such as: continence (92.5%), toileting (91.3%), dressing (87.9%), while bathing ability was impaired mostly or 18.2 percent. Subsequently, the mean of IADL ability among survey involved elderly was found to be 29.9 percent. The health needs of elderly were differed. Due to extensive indicator, 24.8 percent of elderly wanted to admit in a hospital, 20.8 percent - home nursing care and 32.6 percent -involvement in rehabilitation care service. In terms of amount, the maximum needs were eight, while most of elderly requested 1-3 kinds of needs. Conclusions: 1. The impairment of Activity of Daily Living was found to be approximately 22.6 percent, while Instrumental Activity of Daily Living was 29.9 percent among Mongolian elderly people. 2. The impairment level of Activities of Daily Living and Instrumental Activities of Daily Living indicated the requirement of occupational and physical therapy in health care service for the elderly.

Introduction: The mental and behavioral diseases affect in loneliness and discrimination of elderly people and mostly reduce the quality of life of elderly people compared to injury and accidence. Wulf Rossler, Switzerland mentioned that all kinds of mental diseases require long term care, especially rehabilitation. In our country, we lack of survey on determining psychosocial rehabilitation needs for the elderly, therefore it became the background of the research. Goal: Determine the psychosocial rehabilitation needs of Mongolian elderly people Method and materials: The research was carried out by cross sectional method. In the research was involved 1207 elderly, who are retired, of which 60 and over for male and 55 and over for female from one cluster of each economic and geographic regions of Mongolia. The research was conducted by using Geriatric depression test, Spielberg Hanin test to reveal anxiety, Mini mental examination test to assess the cognitive status and AUDIT test to evaluate the alcohol usage. The diagnoses were put according to ICD-10 based on geriatric examination. Results: Out of survey involved 1207 elderly, 32.5 percent (392) referred to men, 67.5 percent (815) to women, and their mean age was 68.1±8.1 (68.9±6.5 in male and 65.7±8.5 in female). While 473 elderly were from Ulaanbaatar city, 734 of them were from 4 regions of countryside. In terms of mental and behavioral diseases, anxiety and depression were prevailing among Mongolian elderly. Thirty eight point five percent of survey involved elderly investigated to have depression and 44 percent - anxiety. Moreover, dementia was found 36 and sleep disorder 28 per 1000 elders. Twenty three point six percent of elderly had slight cognitive impairment, 13.9 percent moderate cognitive impairment, while 2.1 percent had severe cognitive impairment. The cognitive impairment is differed in terms of region. The moderate cognitive impairment predominantly revealed in mountainous and eastern regions, while the severe cognitive impairment was prevailing in central and eastern regions. Due to classification of needs of elderly into medical, financial and other needs, found that, 37 percent of elderly required medical, 33 percent financial and 37 percent other needs. In terms of psychosocial needs, 30.4 percent wanted to have a place for spending free time, 23.9 percent to make new friends and 6.1 percent to hire a job. Also 4.4 percent of elderly had a need of having a caregiver. Conclusions: 1. Out of mental and behavioral diseases, anxiety (38.5 percent) and depression (44 percent) were prevailing among elderly. 2. Each Mongolian elderly had need of 1-2 psychosocial needs. 3. All kinds of psychosocial rehabilitation including the medical, adaptation enhancing and social rehabilitation are equally required for the elderly people.

Coronary heart disease is a leading cause of mortality in many countries. Acute coronary syndrome is the basis pathophysiology of coronary heart disease. Complication of coronary atherosclerosis composes rupture of plaque and erosion of vulnerable plaque. Endothelial dysfunction is main influence of coronary plaque erosion. But then recently research oxidative stress and reaction of immunocomplex is leading cause of coronary plaque rupture. So the research background will study markers of endothelial dysfunction, oxidative stress, immune reaction in the complication of coronaryatherosclerosis. Aim: Determine the effect of some marker for causing complication of the coronary atherosclerosis. The research has been conducted using case-control study method. In the case group, patients with complication of the coronary atherosclerosis as determined by coronary angiography (stenosis >85%) as in the control group healthy people with carotid artery stenosis (<0.7mm) has been involved. In the study we defined Anti-oxLDL (anti-oxidized low density lipoprotein) using ELISA Kit (Eucardio Lab, USA) and oxLDL (oxidized low density lipoprotein) titer by ELISA Kit (Mercadio, USA), ADMA (Asymmetric dimethylarginine) titer by ELISA kit (Eucardio Lab, USA) reagents in the enzyme binding reaction. Total antioxidant capacity (TAC) was determined by using spectrophotometer method. The average age of people involved in the research is 57.2±9.72 and for the average age is case group 28 (32%) and 50 (68%) for the control group. ADMA titer level for complication of coronary atherosclerosis or case group is (30.1±1.98 ng/ml) which is (13.2±0.57 ng/ml) greater than the control group. It was statistically significant result (p<0.001). Also titer level for case group is oxLDL (72±2.75 mU/l), anti-oxLDL antibody (766±29.8 mU/ml), which is oxLDL (45.1±2.28 mU/l), anti-oxLDL antibody(603±17.74 mU/ml) greater than the control group. It was statistically significant result (p<0.001). But TAC titer level for control group is (116±2.47 nmol/l) which is (108.3±5.43 nmol/l) greater than the case group. It was not statistically significant result (p=0.098). According to the Binary Logistic Regression test the anti-oxLDL (OR=0.992, p<0.001), ADMA (OR=0.681, p<0.001), TAC (OR=1.017, p=0.105), oxLDL (OR=0.900, p<0.001) levels significantly influence the complication of coronary atherosclerosis. Therefore according to the Binary Logistic Regression test the anti-oxLDL level high significantly influence the complication of coronary atherosclerosis. Anti-oxLDL antibody titer are correlated directly with oxLDL (r=0.413, p<0.01), ADMA (r=0.42, p<0.001) levels. However, correlated negative directly with TAC (r=-0.233, p<0.01) level. Markers of endothelial dysfunction (ADMA OR=0.681, p<0.001) and oxidative stress (oxLDL, OR=0.900, p<0.001), (anti-oxLDL antibody, OR=0.992, p<0.001) high influence causing of complication of coronary atherosclerosis.

Introduction: Electrolyte values are measured by two different analyzers: arterial blood gas (Point of care) and auto-analyzers. Those two has different methods to measure electrolytes and have several pros and cons. We evaluated if there was agreement between whole blood electrolytes measured by a point-of-care device and serum electrolytes measured using indirect ion-selective electrodes. Materials and methods: An observational cohort study was conducted in 50 paired venous samples from patients admitted in Gurvan gal central hospital. Those were analyzed on OPTC blood gas devise and Roche c-501 auto-analyzer. Statistical analyses were performed using paired t-test and persons’ correlation test. Results: Sodium mean range was 138.54 mmol/l (SD=3.69) by blood gas analyser, but by the automated analyser mean range was 140.75 mmol/l (SD=4.45). Mean difference of the normal sodium group was 1.77 (SD=1.65, p=0.039), and hyposodium group was 4.4 (SD=0.33, p=0.007). Pottasium mean range was 3.13 mmol/l (SD=0.53) by blood gas analyser, but by the automated analyser mean range was 4.42 mmol/l (SD=0.45). Mean difference of the normal sodium group was 0.18 (p<0.001), and hypokalemi group was 1.44 (p<0.001). Conclusion Clinicians should be aware of the difference between whole blood and serum electrolytes. A correction factor needs to be determined at each laboratory.

BackgroundOut of total 209550 cases of cardiovascular diseases in 2011, 66,7% were newly registered cases.Cardiovascular diseases are the number one cause of mortality in Mongolia; an estimated 6291 peopledied from CVDs in 2011, representing 36.7% of all deaths. It shows that CVD mortality level is higherthan in other countries.Materials and MethodsOur survey is a cross sectional study. We have investigated 600 people of the age of 20-40 whowere randomly selected from 6 urban districts of Ulaanbaatar city. With a permission #4 issued bythe Medical Ethics Control Committee of the Ministry of Health on 25th March 2011, our survey wascarried out between the 1st of July 2011 and the 1st of January 2012 based on the Functional DiagnosticLaboratory, Department of Physiology and Pathophysiology, School of Biomedicine, Health SciencesUniversity of Mongolia.ResultsThe CAVI was significantly higher (p<0.001) in 30-40 aged adults (6.68, 95% CI 6.58-6.78) than 20-29 aged adults (6.42, 95% CI 6.32-6.52). Also CAVI has a direct correlation with the cholesterol level(p<0.05, R2=0,011). Serum cholesterol, triglycerides and LDL levels were significantly higher (p<0.05)in men than women. Framingham Heart Score was in the normal range in 99.2% of the participantswith 4 cases having the score of 10% or higher representing a risk score.ConclusionsDislipidemia, overweight and obesity in young adults are the main causes of vascular dysfunctionsleading to cardiovascular diseases. Thus, the findings of the study demonstrate that helping youths todevelop healthy lifestyles including healthy eating and physical activities shall play a critical role for theprevention and intervention programs designed for development of healthy behavior and lifestyle fromchildhood, especially for the male population, are vital for fulfillment of this role.

Coronary heart disease is a leading cause of mortality in many countries. Acute coronary syndrome is the basis pathophysiology of coronary heart disease. Complication of coronary atherosclerosis composes rupture of plaque and erosion of vulnerable plaque. Endothelial dysfunction is main influence of coronary plaque erosion. But then recently research oxidative stress and reaction ofimmunocomplex is leading cause of coronary plaque rupture. So the research background will study markers of endothelial dysfunction, oxidative stress, immune reaction in the complication of coronaryatherosclerosis. Aim: Determine the effect of some marker for causing complication of the coronary atherosclerosis.The research has been conducted using case-control study method. In the case group, patients with complication of the coronary atherosclerosis as determined by coronary angiography (stenosis >85%) as in the control group healthy people with carotid artery stenosis (<0.7mm) has been involved. In the study we defined Anti-oxLDL (anti-oxidized low density lipoprotein) using ELISA Kit (Eucardio Lab, USA) and oxLDL (oxidized low density lipoprotein) titer by ELISA Kit (Mercadio, USA), ADMA (Asymmetric dimethylarginine) titer by ELISA kit (Eucardio Lab, USA) reagents in the enzyme binding reaction. Totalantioxidant capacity (TAC) was determined by using spectrophotometer method. The average age of people involved in the research is 57.2±9.72 and for the average age is case group 28 (32%) and 50 (68%) for the control group. ADMA titer level for complication of coronaryatherosclerosis or case group is (30.1±1.98 ng/ml) which is (13.2±0.57 ng/ml) greater than the control group. It was statistically significant result (p<0.001). Also titer level for case group is oxLDL (72±2.75 mU/l), anti-oxLDL antibody (766±29.8 mU/ml), which is oxLDL (45.1±2.28 mU/l), anti-oxLDL antibody(603±17.74 mU/ml) greater than the control group. It was statistically significant result (p<0.001). But TAC titer level for control group is (116±2.47 nmol/l) which is (108.3±5.43 nmol/l) greater thanthe case group. It was not statistically significant result (p=0.098). According to the Binary LogisticRegression test the anti-oxLDL (OR=0.992, p<0.001), ADMA (OR=0.681, p<0.001), TAC (OR=1.017, p=0.105), oxLDL (OR=0.900, p<0.001) levels significantly influence the complication of coronary atherosclerosis. Therefore according to the Binary Logistic Regression test the anti-oxLDL level high significantly influence the complication of coronary atherosclerosis. Anti-oxLDL antibody titer arecorrelated directly with oxLDL (r=0.413, p<0.01), ADMA (r=0.42, p<0.001) levels. However, correlated negative directly with TAC (r=-0.233, p<0.01) level.Markers of endothelial dysfunction (ADMA OR=0.681, p<0.001) and oxidative stress (oxLDL, OR=0.900, p<0.001), (anti-oxLDL antibody, OR=0.992, p<0.001) high influence causing of complication of coronary atherosclerosis.

Introduction. Stigma and discrimination against patients with mental illness is very common amongst the society. Therefore, this study aims to study the knowledge and understanding of mental illness and attitudes to patient with mental illness, among the general population.Goal. To assess the knowledge and understanding of mental illness and attitude to patient with mental illness among population of Ulaanbaatar city and compare its results with a similar research in carried out in 2002.Methods. The study was conducted in Ulaanbaatar city from February to April, 2008 and included 991 people aged over 18 years. The sample was selected from 30 micro districts of Ulaanbaatar city, The method of sampling was using primary dot in first step, sampling households in mid step and selecting people by using method of Sweden key from household in final step. The study used 30 item standardized questionnaires. Also there were 2 extra cards to read for respondents.Result. Among the respondents, 45% were males and 55 % females. Average age was 37 years. In view of identifying negative attitude of patient with schizophrenia, majority of respondents answered as “loony person” (n=136) and “mad person” (n=83). Conclusion. Although there was stigma amongst the study population, 66% of subjects who were involved in study could give right diagnosis in non professional level and were able to identify symptoms of mental illness suggesting that more than half of the sample studied had some knowledge of mental illness.