1. Liver cirrhosis, liver cancer
Undarmaa D ; Myagmardulam B ; Buyankhishig S ; Naran G
Health Laboratory 2016;5(1):52-54
2.Studying arterial hypertension uncontrol among the population of Selenge province
Erdenesuvd S ; Buyankhishig D ; Zulgerel D ; Ser-Od KH ; Davaa G
Mongolian Medical Sciences 2012;160(2):46-50
Background During the last ten years cardiovascular disease has became one of the priority cause of death in Selenge province, while 23.9 cases in 10.000 population. Studying cause of increasing cardiovascular disease by year and year, connecting with arterial hypertension control and influenced factors is our research work background.GoalTo determine uncontrolled arterial hypertension and evaluate its influenced factors among the population with arterial hypertension in Selenge province.Objectives:1. Research uncontrolled arterial hypertension among the population2. Determine factors that influence uncontrolled arterial hypertensionMaterials and Metods: Research model: Population based moment model of analitic research is used to survey control of population with arterial hypertension. Research coverage and Sampling: Eruu, Zuunburen, and Khutul soums were chosen from 23 soums including center of Selenge province through the random sampling. And then 480 people with arterial hypertension, aged above 18 years were participated in the research. Data was analysed by SPSS 17 program. Collecting information method: Situation of arterial hypertension control is taken by questionnaire method developed by collaboration with WHO and International Association of Arterial Hypertension, and whether follow the drug treatment instruction of physicians is evaluated by MMAS questionnaire method developed by Association of Control Case Managment of America. Arterial hypertension, weight and height of participants were measured. Although people with arterial hypertension under 140-90 mm.Hy are reported “people who are controlling their arterial pressure in normal rate”.ResultsTotally 480 people with arterial hypertension, aged above 18 years were chosen from of Eruu, Zuunburen, and Khutul soums and center of Selenge province. Approximetly, 29.1 percent were male, 70.8 percent were female and average age was 52.43. About 34 percent were high education, 85.8 percent were married and 34.4 percent were retired people. According to the survey, 68 people or 14.1 percent were controlled their arterial pressure/hypertension in normal rate, 412 people or 85.8 percent were uncontrolled their arterial pressure/hypertension in normal rate. Because of the arterial hypertension 59 percent of the participants were under control of physicians. Also there was difference on age and gender with statistical benefit. (p=0.001) People who can control arterial pressure in normal rate were 12.7 percent of people under control of physicians.Conclusions:About 85.8 percent or 412 people with arterial hypertension were uncontrolled, 90 percent were male and 84.1 percent were female. Because of the arterial hypertension, 59 percent of the participants were under control of physicians. But 87.3 percent of them cannot control their arterial pressure/ypertension in normal rate. Physicians control, employment, body mass index and following drug treatment instruction were the factors influence on arterial hypertension control.
3.Gene mutation associated with drug resistance in M.tuberculosis strains isolated from national TB prevalence survey in Mongolia
Tsetsegtuya B ; Baasansuren E ; Oyuntuya T ; Tserelmaa B ; Gundsuren Sh ; Tsolmon B ; Naranbat N ; Tsatsralt-Od B ; Buyankhishig B ; Naranzul D
Mongolian Medical Sciences 2019;187(1):3-10
Background:
According to the First National Tuberculosis (TB) Prevalence Survey in Mongolia the prevalence of
bacteriologically-confirmed pulmonary TB among adults was 559.6 (95% CI: 454.5–664.7) per 100000
population in 2014–2015. This was three times as high as previously estimated. Nationwide anti-tuberculosis (TB) drug resistance survey was conducted in 1999 and 2007 in Mongolia. Share of multidrug resistant TB (MDR-TB) cases among newly notified TB cases increased from 1.0% in 1999 to 1.4% in 2007. Accordingly, we aimed to perform drug susceptibility test on strains isolated from TB Prevalence Survey and to determine the prevalence of drug resistant TB.
Material and Methods:
All 242 MTB strains isolated from the survey TB cases were tested GenoTypeMTBDRplus test and conventional 1st line DST on solid medium.
Result:
Conventional DST and GenoTypeMTBDRplus tests done for 93.8% (227/242) of them and 6.2% (15/242) were tested by GenoTypeMTBDRplus only. A 61.6% (95%CI 55.3-67.4) of all cases were susceptible to first line anti-TB drugs, any drug resistance and MDR-TBdetected as 38.4% (95% CI 32.5-44.7)and 9.5% (95% CI 6.4-13.9), respectively. Prevalence of MDR-TB was7.8% (95% CI 4.9-12.4) among new and 17.9% (95% CI 9.0-32.7) among previously treated cases. The 64 strains were identified as a resistant to isoniazid, 32.8% (42/64) and 65.6% (21/64) were katG, and inhAmutation, respectively. One isolate (1.6%) was mutations in both the inhAand katGgenes.The predominant mutations detected in therpoB were S531L (91.3%) among rifampicin resistant isolates and the mutation in inhAwas C–15T (100%) and katG mutation was S315T1 (100%) among isoniazid-resistant isolates.
Conclusion
Prevalence of cases with DR-TB is high among prevalent TB cases, especially prevalence of MDR-TB among new cases. In comparison to previous studies, DR-TB cases seem to be increased. Rifampicin resistant strains have a mutation of the rpoBand resistance to isoniazid is predominantly associated with the inhA mutation.