2.The Effects of Glutamine on Blastulation of Human Embryos on Vero Cells In Vitro.
Kee Sang PARK ; In Kyung CHOI ; Jin Shik LEE ; Hai Bum SONG
Korean Journal of Fertility and Sterility 1998;25(1):65-70
This study was conducted to investigate the effects of Tissue Culture Medium 199 (TCM) and Dulecco's Modified Eagle Medium (DMEM) on the blastulation and grade of human oocytes on Vero cells in vitro. A cohort of 79 and 93 oocytes in metaphase II stage were used in TCM 199 and DMEM respectively. No differences were found in the nurser of oocytes showing two-pronuclei between TCM (82.3%) and DMEM (86.0%). The number of fertilized oocytes reaching the blastocyst was not significant in TCM (60.0%) and DMEM (63.1%).4 total of 89 blastocysts were categorized into the four grades (BG1, BG2, BG3 and early) depending on their morphology. The number of embryos achieving the blastocyst grade 1 (BG1) was significantly higher (p<0.05) in DMEM (50.8%) than TCM (15.0%). It is concluded that cultured oocytes in DMEM with glutamine on Vero cells should be significantly increased BG1.
Blastocyst
;
Cohort Studies
;
Eagles
;
Embryonic Structures*
;
Glutamine*
;
Humans*
;
Metaphase
;
Oocytes
;
Vero Cells*
3.Visualization of the Pulmonary Arteries in the Patients with Pulmonary Atresia or Hypoplasia by Pulmonary Vein Wedge Angiography.
Dong Soo KIM ; Jun Hee SUL ; Sung Kyu LEE ; Dong Shik CHIN ; Kyu Ok CHOI ; Bum Koo CHO
Korean Circulation Journal 1986;16(1):19-25
The surgical management of patients whose pulmonary arteries are discontinuous from the ventricular mass depends in part on adequate visualization and quantification of the pulmonary arteries. Pulmonary vein wedge angiography has proven effective technique in demonstrating the true mediastinal(intrapericardial) pulmonary arteries(when present) when standard anterograde injections do not suffice. Pulmonary vein wedge angiography was performed in 11 patients during cardiac catheterization at Serverance Hospital Yonsei University College of Medicine between June, 1984 and December, 1985. In all the patients, venous angiography gave a more complete, clear picture of the pulmonary arteries. We feel that pulmonary venous wedge angiography often is superior to and at least complements standard angiographic methods of opacifying the pulmonary artries in patients with pulmonary atresia or occluded pulmonary arteries. We recommend it as a routine part of the evaluation of these patients.
Angiography*
;
Cardiac Catheterization
;
Cardiac Catheters
;
Complement System Proteins
;
Humans
;
Pulmonary Artery*
;
Pulmonary Atresia*
;
Pulmonary Veins*
4.Complete denture treatment using lingualized occlusion scheme at the edentulous patient with severely absorbed flat residual ridges: a case report.
Journal of Dental Rehabilitation and Applied Science 2017;33(3):207-215
Many factors should be considered for successful denture treatment at edentulous patients: support, retention, stability, occlusion, esthetics, etc. The patient who has severely absorbed residual ridges, however, treatments are challenging to satisfy those factors. The dentures that use anatomic artificial teeth show good mastication efficiency and esthetics but, can easily lose stability at absorbed ridges. On the contrary, the dentures that use non-anatomic artificial teeth perform better stability but, lower masticatory efficiency and esthetics at absorbed ridges. The lingualized occlusion, using both anatomic and non-anatomic teeth, introduced for compromise those of the pros and cons. At lingualized occlusion, buccal cusps of the teeth do not contact on centric relation. Therefore, direction of the occlusal force towards lingually, then stability of dentures increases. This case report shows the results of the treatment flat residual ridges using complete dentures with ligualized occlusion to increase dentures stability and satisfactory of the patient.
Bite Force
;
Centric Relation
;
Denture, Complete*
;
Dentures
;
Esthetics
;
Humans
;
Mastication
;
Tooth
;
Tooth, Artificial
5.Shoulder Manipulation After Distention Arthrography: Does Audible Cracking Affect Improvement in Adhesive Capsulitis? A Preliminary Study.
Jun Kyu CHOI ; Seok Beom SON ; Bum Jun PARK ; Seung Nam YANG ; Joon Shik YOON
Annals of Rehabilitation Medicine 2015;39(5):745-751
OBJECTIVE: To investigate whether an audible cracking sound during shoulder manipulation following distention arthrography is clinically significant in patients with adhesive capsulitis of the shoulder. METHODS: A total of 48 patients (31 women, 17 men) with primary adhesive capsulitis of the shoulder completed the study. All participants underwent C-arm-guided arthrographic distention of the glenohumeral joint with injections of a corticosteroid and normal saline. After distention, we performed flexion and abduction manipulation of the shoulder. The patients were grouped into sound and non-sound groups based on the presence or absence, respectively, of an audible cracking sound during manipulation. We assessed shoulder pain and disability based on a Numeric Rating Scale (NRS), the Shoulder Pain and Disability Index (SPADI), and passive range of motion (ROM) measurements (flexion, abduction, internal and external rotation) before the procedure and again at 3 weeks and at 6 weeks after the intervention. RESULTS: The patients were divided into two groups: 21 were included in the sound group and 27 in the non-sound group. In both groups, the results of the NRS, SPADI, and ROM assessments showed statistically significant improvements at both 3 and 6 weeks after the procedure. However, there were no significant differences between the two groups except with respect to external rotation at 6 weeks, at which time the sound group showed a significant improvement in external rotation when compared with the non-sound group (p<0.05). CONCLUSION: These findings showed that manipulation following distention arthrography was effective in decreasing pain and increasing shoulder range of motion. In addition, the presence of an audible cracking sound during manipulation, especially on external rotation, was associated with better shoulder range of motion.
Adhesives*
;
Arthrography*
;
Bursitis*
;
Female
;
Humans
;
Range of Motion, Articular
;
Shoulder Joint
;
Shoulder Pain
;
Shoulder*
6.A Case of Pulmonary Siderosis.
Min Soo HAN ; Dong Il KIM ; Young Soo CHA ; Jin Hwan KOOK ; Ki Heon YOON ; Jeung Sook KIM ; Yoon Jung CHOI ; Hee Jeong AHN ; Bum Shik KIM
Korean Journal of Medicine 1997;53(5):731-735
Pulmonary siderosis is one kind of pneumoconiosis caused by the long term inhalation of iron dust. Iron is deposited in the lungs, usually in the form of iron oxides. Iron oxides are relatively inert particles with a minimal fibrotic response. It occurs in a number of occupations including welding, steel rolling and grinding, casting, iron ore mining and oxyacetylene cutters. We have experienced the first case of pulmonary siderosis in Korea. A 42-year-old woman who had engaged in a metalware manufacturing factory as a manager for 7 years was admitted because of dyspnea on exertion. A pulmonary function test disclosed a mildly obstructive ventilatory defect. Open lung biosy revealed deposition of iron-laden macrophages in most alveolar spaces by which confirmed the diagnosis of pulmonary siderosis. We report a case of pulmonary siderosis with a review of the literature.
Adult
;
Diagnosis
;
Dust
;
Dyspnea
;
Female
;
Humans
;
Inhalation
;
Iron
;
Korea
;
Lung
;
Macrophages
;
Mining
;
Occupations
;
Oxides
;
Pneumoconiosis
;
Respiratory Function Tests
;
Siderosis*
;
Steel
;
Welding
7.Subvalvular Aortic Stenosis Developed after Patch Closure of VSD in A Child: Case Report.
Yong In KIM ; Gun LEE ; Bum Shik KIM ; Suk Min CHOI ; Chung Hyun PARK
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(11):1125-1127
Subvalvular aortic stenosis developed after patch closure of perimembranous VSD is rarely reported. A 18-month-old, 8 kg child with this complication after VSD closure 8 months ago in other hospital has been treated medically and was admitted to this hospital because of severe cardiomegaly and sign of heart failure. Cardiac catheterization revealed 55 mmHg of pressure gradient between aorta and LV cavity. We report one successful redo case of surgically relieved subvalvular aortic stenosis in a child after patch closure of perimembranous VSD.
Aorta
;
Aortic Stenosis, Subvalvular*
;
Cardiac Catheterization
;
Cardiac Catheters
;
Cardiomegaly
;
Child*
;
Heart Failure
;
Humans
;
Infant
8.A Case of Granular Cell Tumor of the Vocal Fold.
Hong Shik CHOI ; Jae Yol LIM ; Jong Bum YOO ; Ji Hoon KIM ; Eun Ah SHIN
Korean Journal of Otolaryngology - Head and Neck Surgery 2002;45(12):1196-1198
Granular cell tumor is a rare, usually benign neoplasm that can occur in various parts of the body. Half of all granular cell tumors occur in the head and neck, with 33% of these occurring in the tongue. The larynx is relatively an uncommon location, accounting for approximately 7% to 10% of all reported cases. Typically, the most common presenting symptom is hoarseness, with some patients also presenting stridor, hemoptysis, dysphagia, and otalgia. But the tumor may be asymptomatic and discovered only incidentally during a routine examination. The diagnosis is usually made on the histopathological findings, characterized by abundant eosinophilic cytoplasm filled with granules of varying sizes. Complete excision with an attempt to maintain normal structures generally results in cure. We experienced a 16-year-old man with laryngeal granular cell tumor, which involves the right true vocal fold. He was successfully treated with local excision under laryngomicroscopic fine dissection. So we present this case with a review of literature.
Adolescent
;
Cytoplasm
;
Deglutition Disorders
;
Diagnosis
;
Earache
;
Eosinophils
;
Granular Cell Tumor*
;
Head
;
Hemoptysis
;
Hoarseness
;
Humans
;
Laryngeal Neoplasms
;
Larynx
;
Neck
;
Respiratory Sounds
;
Tongue
;
Vocal Cords*
9.Usefulness of SPECT Thallium-201 Exercise Myocardial Perfusion Scan in Coronary Artery Disease.
Kee Joon CHOI ; Dong Ju CHOI ; Dae Won SOHN ; June Key CHUNG ; Myoung Mook LEE ; Myung Chul LEE ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE ; Chang Soon KOH ; Bum Woo LEE
Korean Circulation Journal 1992;22(1):77-86
To evaluate the usefullness of SPECT thallium-201 exercise myocardial perfusion scan in coronary artery disease, polar maps processing SPECT images were compared to the exercise treadmill test and the findings of coronary angiographies in 12 normal subjects and 27 patients with the coronary artery disease. The following results were obtained : 1) Sensitivity and specificity of thallium-201 exercise myocardial perfusion scan was 96% and 83%, higher than that of exercise treadmill test(81% abd 61%). 2) In the branches of coronry artery, the sensitivity, specificity and positive predicitive values were 82%, 88%, 90% in left anterior descending artery, 33%, 88%, 57% in left circumflex artery and 69%, 81%, 90% 64% in right coronary artery. 3) The good correlation was observed between the degree of perfusion defect in polar map of thallium-201 myocardial scan in stress and 'myocardial ischemic score' predicted in coronary angiography(p<0.001). Also the degree of reversible perfusion defect had significant correlation with the durtion of exercise. 4) The pulmonary to myocardial ratio of thallium-201 uptake in coronary artery disease group higher than that of angina group. And the perfusion defect with stress and double product at maximal exercise had strongest assocition with the pulmonary to myocardial ratio of thallium-201 uptake by stepwise multiple linear regression. In conclusion, SPECT thallium-201 exercise myocardial perfusion scan is superior to the exercise treadmill test in diagnosing the coronary artery disese and is useful for predicting the sites and degree of coronary arterial stenosis. Also the pulmonary to myocardial ratio of thallium-201 uptake is thought to be good new test index in evaluating the left ventricular function of patients with coronary artery disease.
Arteries
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Exercise Test
;
Humans
;
Linear Models
;
Perfusion*
;
Sensitivity and Specificity
;
Tomography, Emission-Computed, Single-Photon*
;
Ventricular Function, Left
10.Evaluation of Residual Myocardial Ischemia in the Infarct Zone by Dipyridamole Stress SPECT 99mTc-MIBI Myocardial Scan.
Dae Won SOHN ; Dong Jin OH ; Young Dae KIM ; June Key CHUNG ; Myung Mook LEE ; Myung Chul LEE ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE ; Chang Soon KOH ; Bum Woo LEE
Korean Circulation Journal 1990;20(1):68-76
In the recovery phase of acute myocardial infarction, residual ischemia is an important predictor of future cardiac event. To quantitatively evaluate the residual ischemia in the infarct zone and to see whether it can be predicted by particular coronary angiographic characteristics, dipyridamole stress SPECT 99mTc-MIBI myocardial scan was used in 31 patients with uncomplicated acute myocardial infarction. Quantitative assessment of residual ischemia in the infarct zone was made by the ratio of reversible defect in the polar display of SPECT MIBI scan to the total polar map area. Residual ischemia in the infarct zone in these patients does not correlate with patency, collateral circulation or jeopardy score of the infarct related artery. PTCA was performed in 7 patients with significant reversible defect and suitable anatomical lesion to evaluate the reversibility by revascularization. Following the PTCA mean reversible defect decreased significantly from 10.1+/-2.2% to 1.3+/-1.3%(P<0.05). In 10 patients with multivessel disease, 7(54%) out of 13 remote sites showed significant reversible defect showing limited usefulness in the detection of concomitant remote lesion in multivessel disease. Thus dipyridamole stress 99m Tc-MIBI myocardial scan is useful in the evaluation of residual ischemia in the infarct zone, and helpful in the decision making and assessing the result of revascularization.
Arteries
;
Collateral Circulation
;
Decision Making
;
Dipyridamole*
;
Humans
;
Ischemia
;
Myocardial Infarction
;
Myocardial Ischemia*
;
Tomography, Emission-Computed, Single-Photon*