The authors studied ED50 of bethanechol on the contractilities of the smooth muscles isolated from various organs of rat under the presence of atropine (a classical competitive blocker of cholinergic muscarinic receptor) or minaprine (a newly developed antidepressant drug) to investigate the peripheral anticholinergic effect of minaprine. The results were as follow: 1) There was no significant difference between ED50 of bethanechol in the control group and that under the presence of minaprine 10⁻⁸M and 10⁻⁷M in the smooth muscles isolated from the duodenum. 2) There was no significant difference between ED50 of bethanechol in the control group and that under the presence of minaprine 10⁻⁸M and 10⁻⁷M in the smooth muscles isolated from the ascending colon. 3) There was significant difference between ED50 of bethanechol in the control group and that under the presence of minaprine 10⁻⁸M and 10⁻⁷M in the smooth muscles isolated from the urinary bladder (P<0.01) 4) There was significant difference between ED50 of the atropine 10⁻⁸ and minaprine (10⁻⁸M) in the smooth muscles isolated from the urinary bladder (P<0.05).
Animals ; Atropine ; Bethanechol ; Colon, Ascending ; Duodenum ; Muscle, Smooth ; Rats ; Urinary Bladder

The authors studied anxiety, using Zung's Self-Rating Anxiety Scale (SAS), in the subjects of 3,499 male and 1,335 female college freshmen of Yeungnam University. The authors collected the reports of SAS during the periods from January to February, 1986, and applied ANOVA and t-test on anxiety scores in order to compare them between various psychosocial factors, and sexes. The results are as follows: There was significant difference in the mean averages of total anxiety scores between male and female students: male students scored 32.91±7.70, female students scored 34.48±6.00, (P<0.001). The anxiety scores relating to the items of sweating, apprehension, restlessness, and insomnia were relatively higher in both groups. The anxiety scores relating to the items of faintness, mental disintegration, tremors, dizziness were lower in both groups. Thirty-nine male students (1.1%) showed seriously high anxiety scores of 50 or higher, while twenty-one female students (1.6%) showed the same scores. So the authors inferred that the features of anxiety symptoms were much the same in our country, but female showed more various symptoms and higher level of anxiety than males. Male students attending in pharmacy showed higher level of anxiety scores (P<0.01). There was a strong tendency toward higher anxiety scores in the students who were dissatisfied with their home atmosphere, colleges, department and familiarity of parents, and those who had pessimistic views of self image in the past, present, or future, in both groups (P<0.001).
Anxiety* ; Atmosphere ; Dizziness ; Female ; Humans ; Male ; Parents ; Pharmacy ; Psychology ; Psychomotor Agitation ; Recognition (Psychology) ; Sleep Initiation and Maintenance Disorders ; Sweat ; Sweating ; Tremor

No abstract available.
Hemorrhoidectomy*

BACKGROUND: The cornified cell envelope (CE) is a unique structure found in the terminal differentiation of the skin. The precursor proteins of the CE are composed of many candidate structural proteins, among which invalucrin and filaggrin are important ones to participate in the complicated process of forming, the complex structure. OBJECTIVE: The purpose of this study was to evaluate the usefulness of expression of involucrin and filaggrin as markers of terminal differentiation in various skin disorders including tumors. METHODS: Immunohistochemical studies were performed in the formalin-fixed, paraffin-embedded skin samples of non-tumors (41 cases) and tumors (43 cases).
Skin*

No abstract available.
Chondromatosis, Synovial* ; Knee Joint* ; Knee* ; Osteoarthritis*

No abstract available.
Thanatophoric Dysplasia*

No abstract available.
Thanatophoric Dysplasia*

We report two cases of murine typhus diagnosed by indirect immunofluorescent test. The patients showed cardinal symptoms and signs such as fever and chill, general myalgia, intractable headache and typical rash. Laboratory values and histopathologic findings were compatible with murine typhus. The oral administration of doxycycline improved dramatically the clinical manifestations of the two CCLSPS.
Administration, Oral ; Doxycycline ; Exanthema ; Fever ; Headache Disorders ; Humans ; Myalgia ; Typhus, Endemic Flea-Borne*

The authors studied psychoticism, using Derogatis's SCL-90, in the subjects of 3,499 male and 1,335 female college freshmen of Yeungnam University. The authors collected the reports of Self-Rating Psychoticism Scale during the periods from January to February, 1986, and applied ANOVA and t-test on psychoticism scores in order to compare them between various psychosocial factors, and sexes. The results are as follows: There was significant difference in the mean averages of total psychoticism scores between male and female students: male students scored 4.62+4.01, female students scored 5.03+3.89 (P<0.01). Thirteen male students (0.4%) showed high psychoticism scores of 20 or higher, while seven female students (0.5%) showed the same scores. The male students who have maturated in city and the female students whose educational fees were paid by self, showed higher level of psychoticism scores (P<0.05). The male and female students who believed Protestantism showed higher level of psychoticism scores (respectively P<0.05, P<0.01). There was a strong tendency toward higher psychoticism scores in the students who were dissatisfies with their home atmosphere, college, department and familiarity of parents and those who had pessimistic views of self in the past, present or future in both groups (P<0.001).
Atmosphere ; Fees and Charges ; Female ; Humans ; Male ; Parents ; Protestantism ; Psychology ; Recognition (Psychology)

The authors studied the mental health status of the 1989 freshmen of Yeungnam University using the psychotic scale of Derogatis SCL0-90, Zung anxiety and depression scale and MMPI from January 1988 to February 1988. The subjects of this study were contained 3792 students (1206 female, 2586 male). 392 students (10.3%), out of all respondents were screened to fall on high score ranges. The authors performed a second test to 156(39.8% 47 female (30.1%), 109 male (69.9%) of the high-scored in order to clarify their mental health status and analyze various psychosocial factors; using MMPI. The MMPI results were categorized with Lachar's classification. The results were as follows: 1. By the MMPI scores, 24 respondents (15.4%) had neurotic trends, 20 (12.8%) had psychotic trends and 7 (4.5%) had trends of behavior disorder. It was about 1.4% of all 3792 freshmen. 2. On the close examination of the MMPI, 8 respondents were diagnosed for affect disorder, 6 for anxiety disorder, 9 for schizophrenia and 3 for personality disorder. It was 0.7% of all freshmen. 3. One the analysis of the psychosocial factors, the schizophrenic scores were high in the case of unsatisfy in family atmosphere, unsatisfy in marital intimacy of parents, serious in conflicts between father and I, and serious in conflicts between mother and I. 4. The hypochondriacal scores were high in the case of weak in physical condition, having hospitalization experience and physical illness.
Anxiety ; Anxiety Disorders ; Atmosphere ; Classification ; Depression ; Fathers ; Female ; Hospitalization ; Humans ; Male ; Mental Health ; MMPI* ; Mothers ; Parents ; Personality Disorders ; Psychology ; Schizophrenia ; Surveys and Questionnaires