1.A case of contact dermatitis due to oak moss.
Korean Journal of Dermatology 1992;30(3):377-380
Oak moss is a lichen extract obtained from Evernia prunastri and Pseudovernia furfuracea. It is the potent,ial allergen in contact dermatitis to perfumes. Sensitivity to oak moss has been atributed mainly to atranorin, evernic acid, usnic acid and fumarprotocetraric acid. We report a 44-year-old female patient presenting with features of contact dermatitis due to oak moss in perfumes. Patch test results revealed positive reactions to fragrance mix, oak moss, atranorin and evernic acid.
Adult
;
Dermatitis, Contact*
;
Female
;
Humans
;
Lichens
;
Patch Tests
2.Generalized Pseudoxanthoma Elasticum.
Ki Hong LEE ; Ju Eun LEE ; Ki Bum MYUNG
Annals of Dermatology 1993;5(1):38-40
We report a patient with a cutis laxa-like, generalized PXE without systemic involvement. A 28-year-old woman had loose, pendulous skin of the neck, axillae, thighs, trunk and body folds which resulted in a prematurely aged appearance. She had no family history of related diseases. Histological examination showed considerable accumulations of swollen and irregularly clumped fibers in the middle and lower dermis and von Kossa s stain revealed calcium deposits along the altered elastic fibers.
Adult
;
Axilla
;
Calcium
;
Dermis
;
Elastic Tissue
;
Female
;
Humans
;
Neck
;
Pseudoxanthoma Elasticum*
;
Skin
;
Thigh
3.Generalized Pseudoxanthoma Elasticum.
Ki Hong LEE ; Ju Eun LEE ; Ki Bum MYUNG
Annals of Dermatology 1993;5(1):38-40
We report a patient with a cutis laxa-like, generalized PXE without systemic involvement. A 28-year-old woman had loose, pendulous skin of the neck, axillae, thighs, trunk and body folds which resulted in a prematurely aged appearance. She had no family history of related diseases. Histological examination showed considerable accumulations of swollen and irregularly clumped fibers in the middle and lower dermis and von Kossa s stain revealed calcium deposits along the altered elastic fibers.
Adult
;
Axilla
;
Calcium
;
Dermis
;
Elastic Tissue
;
Female
;
Humans
;
Neck
;
Pseudoxanthoma Elasticum*
;
Skin
;
Thigh
4.The effect of azelaic acid and retinoic acid on epidermal melanocytes in UVB-irradiated black mice.
Kyung Won HAN ; Ki Hong LEE ; Ki Bum MYUNG
Korean Journal of Dermatology 1992;30(4):492-498
Increased melanin pigmentation following ultraviolet irradiat.ion is due to increasing tyrosinase activity and multiplicatian of functioning melanocytes. After UV-irradiation, the size of melanocytes increases, and melanocyte dendrites elongatc, and branch. In this experiment, we induced the activation of melanocyts in the epidermis of C57BL black mice by ultraviolet-B(UVB) irradiation and observcd ihe effect of azelaic acid and retinoic acid on the UVB activated epidermal melanocytes. Sixty C57BL black mice were irradiated by UVB 100mJ/cm daily for 10 days, and then azeiaic acid and retinoic acid were topically applied daily for 7 weeks. For the estimation of morphologic change of epidermal melanocytes, light microscopic observation with split DOPA stain was performed at the end of the 1st, 3rd, 5th and 7th week of topical application. The results are summerized as follows : 1. The number, size and circumference of DOPA-positive epidermal melanocytes were significantly decreased in 20% azelaic acid applied group and 30% azelaic acid and 0.05% retinoic acid applied group. 2. In 20% azelaic;i.cid and 0.05% retinoic acid applied group, the number, size and circumference of DOPA-positive epidermal melanocytes were nore significantly decreased than in 20% azelaic acid applied group. In summary, the present study suggets that azelaic acid act as a depigmenting agent on epidermal melanocyte; and such depigmenting effect of azelaic acid was increased by addition of retinoic acid.
Animals
;
Dendrites
;
Dihydroxyphenylalanine
;
Epidermis
;
Melanins
;
Melanocytes*
;
Mice*
;
Monophenol Monooxygenase
;
Pigmentation
;
Tretinoin*
5.Comparative Study for the Comedolytic Effects of Several Topical Acne Remedies on Experimentally Induced Comedones in Rabbits.
Mi Kyung LEE ; Ki Bum MYUNG ; Hong Il KOOK
Korean Journal of Dermatology 1990;28(5):543-549
No abstract available.
Acne Vulgaris*
;
Rabbits*
6.A Case of Cutaneous Leishmaniasis Treated with Cryosurgery.
Hai Min CHOI ; Ki Bum MYUNG ; Hong Il KOOK
Korean Journal of Dermatology 1983;21(2):207-211
Cutaneous leishmaniasis (oriental sore) is usually a self-limited infection of the skin caused by the protozoan Leishmania tropica. The disease is endemic to the Mediterranean, Asia, Africa, and the Middle East. It has been seen in this country among many Korean technical experts and labourers working in the endemic areas of the disease. Our patient had acquired cutaneous leishmaniasis in Saudi Arabia and it had remained active for six months. He had been treated with antimony and metronidazole but failed because of severe side effects. And then we treated the patient witb cryosurgery and the skin lesions were followed by resolution with cosmetically acceptable scar in 4 months. The brief review of literature on the treatment of cutaneous leishmaniasis was undertaken.
Africa
;
Antimony
;
Asia
;
Cicatrix
;
Cryosurgery*
;
Humans
;
Leishmania tropica
;
Leishmaniasis, Cutaneous*
;
Metronidazole
;
Middle East
;
Saudi Arabia
;
Skin
7.A Case of Apocrine Hidrocystoma Occurring in the Female Genitalia.
Kyung Won HAN ; Ki Bum MYUNG ; Hong Il KOOK
Korean Journal of Dermatology 1987;25(1):119-122
A 31-year-old female patient has had a translucent cystic papule on the genitalia since 2 years ago. The diagnosis was confirmed by clinical and histopathological findings. This is the rare case of apocrine hidrocystoma occring in the fernale genitalia in the literature.
Adult
;
Diagnosis
;
Female
;
Female*
;
Genitalia
;
Genitalia, Female*
;
Hidrocystoma*
;
Humans
8.A Case of Trichilemmoma on the Scalp.
Kyung Won HAN ; Ki Bum MYUNG ; Hong Il KOOK
Korean Journal of Dermatology 1987;25(1):115-118
Tricilemmoma is a benign, solitary tumor that may be clinically misdiagnosed as basal cell carcinoma or verruca. It affects frequently the face of elderly rnen. We present herein a case of trichilemrnoma in a 70-year-old Korean wornan who had a slowly growing tumor on the scalp for 50 years. The histopathologic findings revealed lobular acanthosis of glycogeri rich clear cells and palisade of columnar cells resting on prominent basement membrane.
Aged
;
Basement Membrane
;
Carcinoma, Basal Cell
;
Humans
;
Scalp*
;
Warts
9.A Case of Gougerot-Blum Syndrome with Leukemia.
Ki Bum MYUNG ; Hong Jin KIM ; Sung Nack LEE
Korean Journal of Dermatology 1977;15(4):499-503
Gougerost-Blum syndrome is a rare disease and characterized by lichenoid papules in association with purpuric lesions. So far as we know there has been no report of, in literatures, Gougerot-Blum syndrome with leukemia. We experienced a case of typical Gougerrot_Blum syndrome with acute myeloblastic leukemia in a 30 year-old female patient. This patient complained of rashes on whole body for 2 months, and frequent epistaxis and gum bleeding for 20 days. The skin revealed miliary to rice sized rusty colored lichenoid papules on whole body especially on legs and arms. Histopathologically the skin showed the picture of Gougerot-Blum syndrome. On peripheral blood examination and bone marrow aspiration myeloblastic leukemia was confirmed. The patient was treated with 6-mercaptopurine, cytoxan and prednisolone with slight improvement of skin lesions, but no improvement of leukumia itselt.
6-Mercaptopurine
;
Adult
;
Arm
;
Bone Marrow
;
Cyclophosphamide
;
Epistaxis
;
Exanthema
;
Female
;
Gingiva
;
Granulocyte Precursor Cells
;
Hemorrhage
;
Humans
;
Leg
;
Leukemia*
;
Leukemia, Myeloid, Acute
;
Prednisolone
;
Rare Diseases
;
Skin
10.A Case of Atypical Linear Porokeraotsis.
Kyung Ok RYU ; Ki Bum MYUNG ; Hong Il KOOK
Korean Journal of Dermatology 1985;23(5):696-700
Porokeratosis is a familial, chronic, progressive disorder which demonstrates a characteristic clinical and histologic picture. Since Mibelli described three cases in 1893, several clinical variants have been identified, all of which are delineated by a diagnostic histopathologic pattern. We reported a case of atypical linear porokeratosis that had three types of skin lesions. One was the plaque type, as originally described by Mibelli. And others were atypical lesions, as papules and verrucoid hyperkeratotic plaques.
Porokeratosis
;
Skin