1.Leptin: It's Role in Food Intake and Body Weight Control.
Journal of Korean Society of Endocrinology 2000;15(6):722-735
No Abstract Available.
Body Weight*
;
Eating*
;
Leptin*
2.Making the Internet Homepage for a Physician.
Journal of the Korean Medical Association 1999;42(1):48-54
No abstract available.
Internet*
3.Chronic gastritis.
Korean Journal of Medicine 2001;61(2):221-223
No abstract available.
Gastritis*
4.Mechanism of the Epileptic Seizures:A Pathophysiologic Correlation of Clinical and EEG Findings with a Review of the Recent Literature.
Journal of Korean Neurosurgical Society 1975;4(1):73-82
To increase the understanding of the pathophysiologic mechanisms present in epileptic seizures, and to correlate the clinical features with the EEG findings, a review of the recent literature has been made. Epileptic seizures are classified into three types:focal(or partial), generalized and unilateral seizures. In the first type, the focal seizure, there are two sites which have been thought to have one or the other of an initial discharge. The first site is the cortical pole, and the second is the end pole of the interconnected subcortical nuclear system. the cortical pole, and the second is the end pole of the interconnected subcortical nuclear system, the cortical pole is more accessible and vulnerable to seizures. The end pole of the interconnected subcortical nuclear system has two sectors which may be involved. the first sector, the cortico-thalamic system, includes filstly the specific cortico-thalamic system in which the focal stimulation is related to relatively simple somato-motor, sensory and autonomic nervous functions. Secondly, in this first sector, is the non-specific corticothalamic systems which includes the body integrative functions which underlie psychic elaboration of primary sense data. The second sector in the subcortical nuclear system is the amygdalo-brain stem sector. In this non-thalamic system there are the deep temporal structures of the brain such as the amygdalahippocampal complex. These structures are involved in the regulation of emotions, in memory functions and in the maintenance of consciousness. A schematic diagram is prepared to explain the mode of propagation of the epileptic discharge from the initial focus along pathways in the brain structures. This diagram is explained and discussed. The second type of seizure is the generalized seizure. This type is subdivided into two groups:convulsive and non-convulsive. The convulsive group of seizures includes tonic clonic(grandmal), tonic, clonic, infantile spastic, and bilateral myoclonic seizures. These are discussed. The non-convulsive group of seizures includes the following kinds:typical absence(petitmal), atypical absence(petitmal varient), absence status, and atonic seizures. In this group of seizures the initial discharge occurs at the centrencephalon(diencephalo-mesencephalo-rhombencephalon). The intricate mode of propagation of this type of discharge, which involve the recruiting and inhibitory systems, was discussed and also presented schematically.
Brain
;
Consciousness
;
Electroencephalography*
;
Epilepsy
;
Memory
;
Muscle Spasticity
;
Seizures
;
Status Epilepticus
5.Panic Disorder in Primary Care.
Journal of the Korean Academy of Family Medicine 2004;25(3):193-204
No abstract available.
Panic Disorder*
;
Primary Health Care*
6.Therapeutic potential of resveratrol for the treatment of type III Gaucher disease
Neurology Asia 2015;20(1):43-48
Gaucher disease is the most common lysosomal storage disorder. Resveratrol is a natural polyphenol
that possesses a wide range of beneficial effects, including anti-inflammatory, anti-oxidant, and
neuroprotective activities. The aim of this study was to determine if resveratrol has a therapeutic
effect on primary fibroblast cells derived from a patient with type III Gaucher disease. 3-(4,5-
Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays were performed to determine
the effect of resveratrol on cell survival. The expression levels of apoptosis-inducing factor (AIF),
Bcl-2-associated X protein (Bax), caspase-3, acetyl-coenzyme A acetyltransferase 1 (ACAT1), E3-
binding protein (E3BP), and citrate synthase (CS) were evaluated by western blotting to characterize
the effect of resveratrol treatment on Gaucher disease cells. Thin-layer chromatography (TLC) was
carried out to measure changes in glucosylceramide levels in resveratrol-treated patient cells. Resveratrol
increased the viability of patient cells compared to that of untreated control cells. Resveratrol treatment
dose-dependently decreased AIF, Bax, and cleaved caspase-3 levels, whereas ACAT1, E3BP, and CS
expression dose-dependently increased. TLC analysis showed reduced levels of glucosylceramides
in resveratrol-treated patient cells. These findings demonstrate that resveratrol can relieve cellular
stress due to glucosylceramide accumulation, and suggest that it should be studied further as a new
therapeutic approach for the treatment of Gaucher disease.
Gaucher Disease
7.Correlation Between the Expression of Epidermal Growth Factor Receptor and MR Features in Glioma.
Journal of the Korean Society of Magnetic Resonance in Medicine 1997;1(1):125-129
PURPOSE: The aim of this study was to find correlation between the expression of epidermal growth factor receptor (ECFR) and MR findings in the brain glioma. MATERIALS AND METHODS: MR features including edema, margin, necrosis, heterogeneity, hemorrhage and contrast enhancement were retrospectively analyzed with preoperative MR images in 41 patients with proven brain gliomas (8 low grade astrocytomas, 12 anaplastic astrocytomas, 21 glioblastoma multiformes). Immunohistochemical study of EGFR was done and their expressions were graded by both stained distribution and intensity. Correlation analysis between the MR features and EGFR expressions was done. RESULTS: Peritumoral edema was correlated with both distribution (r=0.71, p=0.00) and stain intensity (r=0.69, p=0.00) of EGFR expression. Other MR features showed no statistical correlation with EGFR expression. CONCLUSION: MRI is useful in evaluation of brain glioma, and peritumoral edema is useful findings that suggests EGFR expression as well as malignant histopathologic grade of the tumor.
Astrocytoma
;
Brain
;
Edema
;
Epidermal Growth Factor*
;
Glioblastoma
;
Glioma*
;
Hemorrhage
;
Humans
;
Magnetic Resonance Imaging
;
Necrosis
;
Population Characteristics
;
Receptor, Epidermal Growth Factor*
;
Retrospective Studies
8.Stercoraceous Ulcer of the Cecum: A case report.
Korean Journal of Gastrointestinal Endoscopy 1983;3(1):108-113
Stercoraceous ulcerations of the colon are produced by hard fecaloma that collect in the coton. Bleeding and more seriously perforation are complications of these ulcerations. These are generally thought to be rare, but this may reflect the difficulty of establishing the diagnosis, both before and during operation. This disease is relatively neglected as well. This is reflected by the small number of case reported in the literature. Authors report a case of stercoraceous ulcer of cecum which confirmed under the colonofiberscopy and managed in the Department of General Surgery, College of Medicine, Ewha Womans University,
Cecum*
;
Colon
;
Diagnosis
;
Female
;
Hemorrhage
;
Humans
;
Ulcer*
9.A study on the peripheral anticholinergic effect of quinupramine.
Journal of Korean Neuropsychiatric Association 1991;30(2):296-302
No abstract available.
10.Longitudinal Melanonychia in SLE.
The Journal of the Korean Rheumatism Association 2006;13(2):182-183
No abstract available.